thyroxine has been researched along with Rett Syndrome in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marshall, B | 1 |
| Chernoff, K | 1 |
| Saenger, P | 1 |
| Mytinger, JR | 1 |
| Blackman, JA | 1 |
| Goodkin, HP | 1 |
| Kit, B | 1 |
| Franceschini, B | 1 |
| Cooke, DW | 1 |
| Naidu, S | 1 |
| Plotnick, L | 1 |
| Berkovitz, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004807] | 120 participants | Interventional | 1995-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for thyroxine and Rett Syndrome
| Article | Year |
|---|---|
Index of suspicion.
Topics: Adolescent; Child; Diagnosis, Differential; Esophageal Perforation; Female; Humans; Hyperplasia; Hyp | 2008 |
Abnormalities of thyroid function and glucose control in subjects with Rett syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Blood Glucose; Child; Child, Preschool; Glucose Tolerance Test; | 1995 |