thyroxine has been researched along with Retinopathy of Prematurity in 5 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 7.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| " Premature infants often require outpatient care for bronchopulmonary dysplasia, apnea, retinopathy of prematurity, intraventricular hemorrhage, hearing loss, hypothyroxinemia, anemia, neurodevelopmental sequelae, assessment of growth and nutrition, immunizations, and psychosocial stress." | 4.77 | Continuing care for the preterm infant after dismissal from the neonatal intensive care unit. ( Berseth, CL; Swanson, JA, 1987) |
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 3.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Korkmaz, L | 1 |
| Baştuğ, O | 1 |
| Daar, G | 1 |
| Korkut, S | 1 |
| Özdemir, A | 1 |
| Adnan Öztürk, M | 1 |
| Güneş, T | 1 |
| Kurtoğlu, S | 1 |
| Mookadam, M | 2 |
| Leske, DA | 2 |
| Fautsch, MP | 2 |
| Lanier, WL | 2 |
| Holmes, JM | 2 |
| Harrold, J | 1 |
| Schmidt, B | 1 |
| Swanson, JA | 1 |
| Berseth, CL | 1 |
2 reviews available for thyroxine and Retinopathy of Prematurity
| Article | Year |
|---|---|
Evidence-based neonatology: making a difference beyond discharge from the neonatal nursery.
Topics: Breast Feeding; Cryotherapy; Cyclooxygenase Inhibitors; Evidence-Based Medicine; Extracorporeal Memb | 2002 |
Continuing care for the preterm infant after dismissal from the neonatal intensive care unit.
Topics: Anemia, Neonatal; Apnea; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Hearing Loss; Humans; Infa | 1987 |
3 other studies available for thyroxine and Retinopathy of Prematurity
| Article | Year |
|---|---|
The effects of thyroid function on retinopathy of prematurity.
Topics: Bronchopulmonary Dysplasia; Case-Control Studies; Comorbidity; Female; Humans; Infant, Extremely Pre | 2016 |
The anti-thyroid drug methimazole induces neovascularization in the neonatal rat analogous to ROP.
Topics: Animals; Animals, Newborn; Antithyroid Agents; Female; Humans; Infant, Newborn; Insulin-Like Growth | 2004 |
Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity.
Topics: Acidosis; Ammonium Chloride; Animals; Animals, Newborn; Antithyroid Agents; Blood Gas Analysis; Dise | 2005 |