thyroxine has been researched along with Retinal Neovascularization in 3 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Retinal Neovascularization: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 7.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 3.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| "Retinal neovascularization was quantitated at P18." | 1.38 | Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac). ( Duh, EJ; Gong, J; Wei, Y; Xu, Z; Yoshida, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, T | 1 |
| Gong, J | 1 |
| Xu, Z | 1 |
| Wei, Y | 1 |
| Duh, EJ | 1 |
| Mookadam, M | 2 |
| Leske, DA | 2 |
| Fautsch, MP | 2 |
| Lanier, WL | 2 |
| Holmes, JM | 2 |
3 other studies available for thyroxine and Retinal Neovascularization
| Article | Year |
|---|---|
Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac).
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Cell Surviva | 2012 |
The anti-thyroid drug methimazole induces neovascularization in the neonatal rat analogous to ROP.
Topics: Animals; Animals, Newborn; Antithyroid Agents; Female; Humans; Infant, Newborn; Insulin-Like Growth | 2004 |
Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity.
Topics: Acidosis; Ammonium Chloride; Animals; Animals, Newborn; Antithyroid Agents; Blood Gas Analysis; Dise | 2005 |