thyroxine has been researched along with Reperfusion Injury in 10 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methimazole exerts a protective role on lungs during hepatic ischemia-reperfusion injury, which can be attributed to its anti-inflammatory and anti-oxidant effects rather than hypothyroidism alone." | 7.74 | Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism. ( Bilgihan, A; Demirci, C; Gözalan, U; Kama, NA; Tütüncü, T; Yüksek, YN, 2007) |
| " The present study evaluated triiodothyronine (T3), thyroxine, and thyroid-stimulating hormone concentrations before and early after transplantation relative to the occurrence of delayed graft function." | 3.77 | Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation. ( Bonakdaran, S; Hekmat, R; Javadi, Z; Javain, ML, 2011) |
| "Methimazole exerts a protective role on lungs during hepatic ischemia-reperfusion injury, which can be attributed to its anti-inflammatory and anti-oxidant effects rather than hypothyroidism alone." | 3.74 | Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism. ( Bilgihan, A; Demirci, C; Gözalan, U; Kama, NA; Tütüncü, T; Yüksek, YN, 2007) |
| " Thyroxine administration increased susceptibility to ischemia-reperfusion injury, whereas the antithyroid agent propylthiouracil reduced the deleterious effects associated with cold storage." | 3.70 | The effects of thyroid hormone modulation on rat liver injury associated with ischemia-reperfusion and cold storage. ( Bellomo, G; Feletti, F; Gualea, MR; Imberti, R; Poma, G; Preseglio, I; Richelmi, P; Vairetti, M, 1998) |
| "Reperfusion injury was assessed by post-ischemic recovery of left ventricular developed pressure (LVDP%) and LDH release." | 1.37 | Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor. ( Brozou, V; Cokkinos, DV; Galanopoulos, G; Kostopanagiotou, G; Mourouzis, I; Pantos, C; Saranteas, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Qi, X | 1 |
| Jia, W | 1 |
| Ellett, JD | 1 |
| Evans, ZP | 1 |
| Fiorini, JH | 1 |
| Fiorini, RN | 1 |
| Haines, JK | 1 |
| Schmidt, MG | 1 |
| Chavin, KD | 1 |
| Peng, PH | 1 |
| Chao, HM | 1 |
| Juan, SH | 1 |
| Chen, CF | 1 |
| Liu, JH | 1 |
| Ko, ML | 1 |
| Hekmat, R | 1 |
| Javadi, Z | 1 |
| Javain, ML | 1 |
| Bonakdaran, S | 1 |
| Pantos, C | 1 |
| Mourouzis, I | 1 |
| Saranteas, T | 1 |
| Brozou, V | 1 |
| Galanopoulos, G | 1 |
| Kostopanagiotou, G | 1 |
| Cokkinos, DV | 1 |
| Erkan, E | 1 |
| Sakarcan, A | 1 |
| Haklar, G | 1 |
| Yalcin, S | 1 |
| Tütüncü, T | 1 |
| Demirci, C | 1 |
| Gözalan, U | 1 |
| Yüksek, YN | 1 |
| Bilgihan, A | 1 |
| Kama, NA | 1 |
| Imberti, R | 2 |
| Vairetti, M | 2 |
| Rastogi, L | 1 |
| Gupta, S | 1 |
| Godbole, MM | 1 |
| Gualea, MR | 1 |
| Feletti, F | 1 |
| Poma, G | 1 |
| Richelmi, P | 1 |
| Preseglio, I | 1 |
| Bellomo, G | 1 |
10 other studies available for thyroxine and Reperfusion Injury
| Article | Year |
|---|---|
3,3',5-triiodothyroxine inhibits apoptosis and oxidative stress by the PKM2/PKM1 ratio during oxygen-glucose deprivation/reperfusion AC16 and HCM-a cells: T3 inhibits apoptosis and oxidative stress by PKM2/PKM1 ratio.
Topics: Apoptosis; Carrier Proteins; Cell Line; Glucose; Humans; Iodide Peroxidase; Membrane Proteins; Myocy | 2016 |
The use of the Papworth cocktail is detrimental to steatotic livers after ischemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Fatty Liver; Liver; Liver Transplantation; Ma | 2008 |
Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Female; Hem | 2011 |
Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation.
Topics: Cross-Sectional Studies; Delayed Graft Function; Female; Humans; Kidney Failure, Chronic; Kidney Tra | 2011 |
Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor.
Topics: Amiodarone; Animals; Dronedarone; Drug Synergism; Heart; In Vitro Techniques; Male; Myocardial Contr | 2011 |
Thyroxine prevents reoxygenation injury in isolated proximal tubule cells.
Topics: Animals; Cell Separation; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Hypoxia; Kidney Tubule | 2003 |
Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antithyroid Agents; Disease Models, Animal; Hepatic | 2007 |
Thyroid hormone therapy in organ donors.
Topics: Animals; Humans; Liver; Liver Transplantation; Oxidative Stress; Rats; Reperfusion Injury; Thyroxine | 2007 |
Pathophysiological basis for thyrotoxicosis as an aggravating factor in post-ischemic brain injury in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dose-Response Relationship, Drug; Glutathione; | 2008 |
The effects of thyroid hormone modulation on rat liver injury associated with ischemia-reperfusion and cold storage.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine Transaminase; Animals; Antithyroid Agents; Bile | 1998 |