thyroxine has been researched along with Pulmonary Fibrosis in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 7.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 3.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bagnato, G | 2 |
| Bitto, A | 1 |
| Irrera, N | 1 |
| Pizzino, G | 1 |
| Sangari, D | 1 |
| Cinquegrani, M | 1 |
| Roberts, W | 1 |
| Atteritano, M | 1 |
| Altavilla, D | 1 |
| Squadrito, F | 1 |
| Saitta, A | 1 |
| Foresti, V | 1 |
| Pepe, R | 1 |
| Parisio, E | 1 |
| De Filippi, G | 1 |
| Scolari, N | 1 |
| Frigerio, C | 1 |
2 other studies available for thyroxine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal | 2013 |
Angiotensin-converting enzyme as a possible marker for lung toxicity in amiodarone-treated patients.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Biomarkers; Female; Humans; Lung | 1989 |