thyroxine has been researched along with Polycystic Ovarian Syndrome in 29 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-three patients with PCOS were specifically selected for being either treated with levothyroxine for a previous diagnosis of hypothyroidism (n = 7), untreated subclinically hypothyroid (n = 2) or euthyroid without levothyroxine treatment (n = 24) before the starting of metformin." | 9.15 | Thyroidal effect of metformin treatment in patients with polycystic ovary syndrome. ( Botta, R; Cappelli, C; Castellano, M; Chiovato, L; De Cata, P; Dionisio, R; Iacobello, C; Magri, F; Nappi, RE; Rotondi, M, 2011) |
| "The objective of the present study was to investigate the effect of melatonin and L-thyroxine (T4) on the expression of various receptors, and some metabolic, reproductive, and gonadotropic hormones in letrozole-induced polycystic ovary syndrome (PCOS) in rats." | 8.12 | Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome. ( Brown, GM; Cardinali, DP; Ghosh, H; Manzar, MD; Pandi-Perumal, SR; Rai, S; Reiter, RJ, 2022) |
| "This observational, retrospective study utilized EHR data from 52 hospitals for COVID-19 patients with PCOS or prediabetes treated with metformin or levothyroxine/ondansetron (controls)." | 8.12 | Metformin is associated with reduced COVID-19 severity in patients with prediabetes. ( Antony, B; Blau, H; Bramante, C; Casiraghi, E; Chan, LE; Coleman, B; Gargano, M; Haendel, M; Harris, NL; Laraway, B; Reese, J; Robinson, PN; Sahner, D; Valentini, G; Wilkins, K; Zaman, A, 2022) |
| "Our study aimed to describe levothyroxine prescription patterns and trends over time among pregnant women with subclinical hypothyroidism (SCH) in the United Kingdom." | 8.02 | Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment. ( Filion, KB; Grandi, SM; Platt, RW; Reynier, P; Yu, OHY; Yu, YH, 2021) |
| "Our aim was to determine whether serum leptin level is regulated by thyroid hormones, lipid metabolic products and insulin resistance status in women with polycystic ovary syndrome (PCOS)." | 7.72 | Is serum leptin level regulated by thyroid functions, lipid metabolism and insulin resistance in polycystic ovary syndrome? ( Baysal, B; Erel, CT; Gezer, A; Kaleli, S; Senturk, LM; Tasan, E, 2003) |
| "The purpose of this study was to determine whether polycystic ovary syndrome (PCOS) and nonclassic 21-hydroxylase deficiency (CAH) are related to hyperhomocysteinemia, and to investigate if there is a correlation between homocysteine levels and insulin sensitivity in women with PCOS and CAH." | 7.72 | Plasma homocysteine levels in polycystic ovary syndrome and congenital adrenal hyperplasia. ( Bayraktar, F; Dereli, D; Ozgen, AG; Yilmaz, C, 2004) |
| "Thirty-three patients with PCOS were specifically selected for being either treated with levothyroxine for a previous diagnosis of hypothyroidism (n = 7), untreated subclinically hypothyroid (n = 2) or euthyroid without levothyroxine treatment (n = 24) before the starting of metformin." | 5.15 | Thyroidal effect of metformin treatment in patients with polycystic ovary syndrome. ( Botta, R; Cappelli, C; Castellano, M; Chiovato, L; De Cata, P; Dionisio, R; Iacobello, C; Magri, F; Nappi, RE; Rotondi, M, 2011) |
| "The objective of the present study was to investigate the effect of melatonin and L-thyroxine (T4) on the expression of various receptors, and some metabolic, reproductive, and gonadotropic hormones in letrozole-induced polycystic ovary syndrome (PCOS) in rats." | 4.12 | Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome. ( Brown, GM; Cardinali, DP; Ghosh, H; Manzar, MD; Pandi-Perumal, SR; Rai, S; Reiter, RJ, 2022) |
| "This observational, retrospective study utilized EHR data from 52 hospitals for COVID-19 patients with PCOS or prediabetes treated with metformin or levothyroxine/ondansetron (controls)." | 4.12 | Metformin is associated with reduced COVID-19 severity in patients with prediabetes. ( Antony, B; Blau, H; Bramante, C; Casiraghi, E; Chan, LE; Coleman, B; Gargano, M; Haendel, M; Harris, NL; Laraway, B; Reese, J; Robinson, PN; Sahner, D; Valentini, G; Wilkins, K; Zaman, A, 2022) |
| "Our study aimed to describe levothyroxine prescription patterns and trends over time among pregnant women with subclinical hypothyroidism (SCH) in the United Kingdom." | 4.02 | Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment. ( Filion, KB; Grandi, SM; Platt, RW; Reynier, P; Yu, OHY; Yu, YH, 2021) |
| "To describe 2 cases of primary hypothyroidism, precocious puberty, large multicystic ovaries, possible diagnostic dilemma, unilateral oophorectomies, and subsequent response to levothyroxine replacement therapy." | 3.74 | Precocious puberty and large multicystic ovaries in young girls with primary hypothyroidism. ( Deepak, T; Sanjay, S; Sanjeevaiah, AR; Sharada, A; Srikanta, SS, 2007) |
| "Our aim was to determine whether serum leptin level is regulated by thyroid hormones, lipid metabolic products and insulin resistance status in women with polycystic ovary syndrome (PCOS)." | 3.72 | Is serum leptin level regulated by thyroid functions, lipid metabolism and insulin resistance in polycystic ovary syndrome? ( Baysal, B; Erel, CT; Gezer, A; Kaleli, S; Senturk, LM; Tasan, E, 2003) |
| "The purpose of this study was to determine whether polycystic ovary syndrome (PCOS) and nonclassic 21-hydroxylase deficiency (CAH) are related to hyperhomocysteinemia, and to investigate if there is a correlation between homocysteine levels and insulin sensitivity in women with PCOS and CAH." | 3.72 | Plasma homocysteine levels in polycystic ovary syndrome and congenital adrenal hyperplasia. ( Bayraktar, F; Dereli, D; Ozgen, AG; Yilmaz, C, 2004) |
| "Thus, autoimmune thyroiditis (AIT) could be more prevalent among women with PCOS." | 1.42 | Polycystic ovary syndrome and chronic autoimmune thyroiditis. ( Benetti-Pinto, CL; Garmes, HM; Jales, RM; Juliato, CR; Novais, Jde S, 2015) |
| " No correlation was found between duration or dosage of treatment and BMI-SDS, height-SDS, or androgen level." | 1.34 | Endocrine effects of valproate in adolescent girls with epilepsy. ( de Vries, L; Goldberg-Stern, H; Karasik, A; Kiviti, S; Landau, Z; Phillip, M, 2007) |
| "During a 30 months period, two women of primary hypothyroidism (2/13; 1." | 1.29 | Hypothyroidism presenting with polycystic ovary syndrome. ( Nagamani, G; Sridhar, GR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 4 (13.79) | 2.80 |
| Authors | Studies |
|---|---|
| Ghosh, H | 1 |
| Rai, S | 1 |
| Manzar, MD | 1 |
| Pandi-Perumal, SR | 1 |
| Brown, GM | 1 |
| Reiter, RJ | 1 |
| Cardinali, DP | 1 |
| Chan, LE | 3 |
| Casiraghi, E | 3 |
| Laraway, B | 3 |
| Coleman, B | 3 |
| Blau, H | 3 |
| Zaman, A | 3 |
| Harris, NL | 3 |
| Wilkins, K | 3 |
| Antony, B | 3 |
| Gargano, M | 3 |
| Valentini, G | 3 |
| Sahner, D | 3 |
| Haendel, M | 3 |
| Robinson, PN | 3 |
| Bramante, C | 3 |
| Reese, J | 3 |
| Riaz, M | 1 |
| Ibrahim, MN | 1 |
| Laghari, TM | 1 |
| Hanif, MI | 1 |
| Raza, J | 1 |
| Yu, YH | 1 |
| Filion, KB | 1 |
| Reynier, P | 1 |
| Platt, RW | 1 |
| Yu, OHY | 1 |
| Grandi, SM | 1 |
| Kim, SH | 1 |
| Liu, M | 1 |
| Jin, HS | 1 |
| Park, S | 1 |
| Grolmusz, VK | 1 |
| Stenczer, B | 1 |
| Fekete, T | 1 |
| Szendei, G | 1 |
| Patócs, A | 1 |
| Rácz, K | 1 |
| Reismann, P | 1 |
| Novais, Jde S | 1 |
| Benetti-Pinto, CL | 1 |
| Garmes, HM | 1 |
| Jales, RM | 1 |
| Juliato, CR | 1 |
| Calvar, CE | 1 |
| Bengolea, SV | 1 |
| Deutsch, SI | 1 |
| Hermes, R | 1 |
| Ramos, G | 1 |
| Loyato, M | 1 |
| Muscogiuri, G | 1 |
| Palomba, S | 1 |
| Caggiano, M | 1 |
| Tafuri, D | 1 |
| Colao, A | 1 |
| Orio, F | 1 |
| Yin, D | 1 |
| Ruan, X | 1 |
| Tian, X | 1 |
| Du, J | 1 |
| Zhao, Y | 1 |
| Cui, Y | 1 |
| Li, Y | 1 |
| Mueck, AO | 1 |
| Rotondi, M | 1 |
| Cappelli, C | 1 |
| Magri, F | 1 |
| Botta, R | 1 |
| Dionisio, R | 1 |
| Iacobello, C | 1 |
| De Cata, P | 1 |
| Nappi, RE | 1 |
| Castellano, M | 1 |
| Chiovato, L | 1 |
| Petríková, J | 1 |
| Figurová, J | 1 |
| Dravecká, I | 1 |
| Lazúrová, I | 1 |
| Zou, S | 1 |
| Sang, Q | 1 |
| Wang, H | 1 |
| Feng, R | 1 |
| Li, Q | 1 |
| Zhao, X | 1 |
| Xing, Q | 1 |
| Jin, L | 1 |
| He, L | 1 |
| Wang, L | 1 |
| Erel, CT | 1 |
| Senturk, LM | 1 |
| Kaleli, S | 1 |
| Gezer, A | 1 |
| Baysal, B | 1 |
| Tasan, E | 1 |
| Chattopadhyay, A | 1 |
| Kumar, V | 1 |
| Marulaiah, M | 1 |
| Bayraktar, F | 1 |
| Dereli, D | 1 |
| Ozgen, AG | 1 |
| Yilmaz, C | 1 |
| de Vries, L | 1 |
| Karasik, A | 1 |
| Landau, Z | 1 |
| Phillip, M | 1 |
| Kiviti, S | 1 |
| Goldberg-Stern, H | 1 |
| Mohsin, F | 1 |
| Nahar, N | 1 |
| Azad, K | 1 |
| Nahar, J | 1 |
| Sanjeevaiah, AR | 1 |
| Sanjay, S | 1 |
| Deepak, T | 1 |
| Sharada, A | 1 |
| Srikanta, SS | 1 |
| Puleo, JG | 1 |
| Ory, SJ | 1 |
| Sridhar, GR | 1 |
| Nagamani, G | 1 |
| Geary, M | 1 |
| Hindmarsh, PC | 1 |
| Eagleson, CA | 1 |
| Gingrich, MB | 1 |
| Pastor, CL | 1 |
| Arora, TK | 1 |
| Burt, CM | 1 |
| Evans, WS | 1 |
| Marshall, JC | 1 |
| Dhanwal, D | 1 |
| Tandon, N | 1 |
| Andersen, RN | 1 |
| Givens, JR | 1 |
| Wiser, WL | 1 |
| Umstot, ES | 1 |
| Malarkey, WB | 1 |
| Beck, P | 1 |
| Marsh, M | 1 |
| Burger, HG | 1 |
| Akopian, SS | 1 |
| Mirimanova, RP | 1 |
| Kazarian, LS | 1 |
| Benjamin, F | 1 |
| Deutsch, S | 1 |
| Saperstein, H | 1 |
| Seltzer, VL | 1 |
2 reviews available for thyroxine and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
Childhood influences on adult disease.
Topics: Adult; Age Factors; Antineoplastic Agents; Asthma; Child; Congenital Hypothyroidism; Diabetes Mellit | 1998 |
Update on endocrinology.
Topics: Calcitonin; Diphosphonates; Female; Humans; Osteitis Deformans; Polycystic Ovary Syndrome; Thyroid F | 1992 |
3 trials available for thyroxine and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
Lack of association between C385A functional polymorphism of the fatty acid amide hydrolase gene and polycystic ovary syndrome.
Topics: Adult; Alleles; Amidohydrolases; DNA Mutational Analysis; Female; Gene Frequency; Humans; Insulin; P | 2013 |
Thyroidal effect of metformin treatment in patients with polycystic ovary syndrome.
Topics: Adult; Female; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Polycystic Ovary Syndrome; Th | 2011 |
Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone.
Topics: 17-alpha-Hydroxyprogesterone; Activity Cycles; Adult; Androgen Antagonists; Body Mass Index; Dehydro | 2000 |
24 other studies available for thyroxine and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome.
Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Female; Gene Expression; Gene Expression R | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic Sta | 2022 |
Van Wyk Grumbach Syndrome.
Topics: Child; Female; Humans; Hypothyroidism; Ovarian Cysts; Polycystic Ovary Syndrome; Puberty, Precocious | 2020 |
Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment.
Topics: Adult; Asymptomatic Diseases; Diabetes Mellitus; Female; Humans; Hypothyroidism; Infertility, Female | 2021 |
High Genetic Risk Scores of ASIC2, MACROD2, CHRM3, and C2orf83 Genetic Variants Associated with Polycystic Ovary Syndrome Impair Insulin Sensitivity and Interact with Energy Intake in Korean Women.
Topics: Acid Sensing Ion Channels; Adult; Blood Glucose; Body Mass Index; C-Reactive Protein; Cohort Studies | 2019 |
Polycystic ovary syndrome and chronic autoimmune thyroiditis.
Topics: Adult; Autoantibodies; Comorbidity; Cross-Sectional Studies; Female; Humans; Polycystic Ovary Syndro | 2015 |
[High frequency of thyroid abnormalities in polycystic ovary syndrome].
Topics: Adolescent; Adult; Blood Glucose; Case-Control Studies; Female; Homeostasis; Humans; Insulin; Polycy | 2015 |
Low 25 (OH) vitamin D levels are associated with autoimmune thyroid disease in polycystic ovary syndrome.
Topics: Adolescent; Adult; Autoantibodies; Female; Humans; Iodide Peroxidase; Polycystic Ovary Syndrome; Thy | 2016 |
The relationship between thyroid function and metabolic changes in Chinese women with polycystic ovary syndrome.
Topics: Adult; Apolipoproteins A; Apolipoproteins B; Body Mass Index; China; Cholesterol; Female; Follicle S | 2017 |
[Is polycystic ovary syndrome associated with autoimmune thyroiditis?].
Topics: Adult; Autoantibodies; Female; Humans; Iodide Peroxidase; Middle Aged; Polycystic Ovary Syndrome; Th | 2012 |
Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Estrogens, Catechol; Female; Genetic | 2013 |
Is serum leptin level regulated by thyroid functions, lipid metabolism and insulin resistance in polycystic ovary syndrome?
Topics: Adult; Blood Glucose; Body Mass Index; Case-Control Studies; Cholesterol; Cholesterol, HDL; Choleste | 2003 |
Polycystic ovaries, precocious puberty and acquired hypothyroidism: The Van Wyk and Grumbach syndrome.
Topics: Child; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Polycystic Ovary Syndrome; Puber | 2003 |
Plasma homocysteine levels in polycystic ovary syndrome and congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Adult; Blood Glucose; Cholesterol; Estradiol; Female; Follicle Stim | 2004 |
Endocrine effects of valproate in adolescent girls with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Body Height; Body Mass Index; Child; Comorbidity; Epilepsy; Fema | 2007 |
Vaginal bleeding with multicystic ovaries and a pituitary mass in a child with severe hypothyroidism.
Topics: Child; Female; Humans; Hypothyroidism; Metrorrhagia; Pituitary Neoplasms; Polycystic Ovary Syndrome; | 2007 |
Precocious puberty and large multicystic ovaries in young girls with primary hypothyroidism.
Topics: Adolescent; Child, Preschool; Female; Humans; Hypothyroidism; Ovariectomy; Polycystic Ovary Syndrome | 2007 |
Nonpuerperal mastitis associated with galactorrhea.
Topics: Adult; Bromocriptine; Female; Follicle Stimulating Hormone; Galactorrhea; Humans; Lactation Disorder | 1983 |
Hypothyroidism presenting with polycystic ovary syndrome.
Topics: Adult; Female; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Ovary; Polycystic Ovary Syndr | 1993 |
Isolated menarche and multicystic ovaries in a 7 1/2 year girl with hypothyroidism.
Topics: Child; Female; Follow-Up Studies; Humans; Hypothyroidism; Menarche; Polycystic Ovary Syndrome; Puber | 2001 |
Response of the binding capacity of plasma testosterone-estradiol-binding globulin to norethindrone, 2 mg., and mestranol, 0.1 mg., in polycystic ovarian disease.
Topics: Carrier Proteins; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Mestranol; Norethindrone; Po | 1976 |
Twenty-four-hour prolactin profiles in normal and disease states: failure of thyroxine to modify prolactin secretion.
Topics: Adult; Female; Galactorrhea; Humans; Lactation Disorders; Pituitary Neoplasms; Polycystic Ovary Synd | 1975 |
[Thyroxine, triiodothyronine and thyrotropic hormone levels in the blood of patients with sclerocystic ovary syndrome of central origin].
Topics: Adolescent; Adult; Female; Humans; Hypothalamo-Hypophyseal System; Polycystic Ovary Syndrome; Thyrot | 1986 |
Prevalence of and markers for the attenuated form of congenital adrenal hyperplasia and hyperprolactinemia masquerading as polycystic ovarian disease.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Dehydroe | 1986 |