Page last updated: 2024-11-06

thyroxine and Poisoning

thyroxine has been researched along with Poisoning in 18 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"Levothyroxine (LT), T4, poisoning is rarely associated with a severe outcome."8.91Levothyroxine Poisoning - Symptoms and Clinical Outcome. ( Dalhoff, K; Jürgens, G; Nygaard, B; Saedder, EA; Wikkelsoe, M, 2015)
"We report a toddler with massive thyroid hormone poisoning in whom the addition of iopanoic acid to the treatment regimen (propylthiouracil and propranolol) resulted in a dramatic clinical and biochemical improvement."7.70Successful treatment of massive acute thyroid hormone poisoning with iopanoic acid. ( Braverman, LE; Brown, RS; Cohen, JH, 1998)
"We report a toddler with massive thyroid hormone poisoning in whom the addition of iopanoic acid to the treatment regimen (propylthiouracil and propranolol) resulted in a dramatic clinical and biochemical improvement."3.70Successful treatment of massive acute thyroid hormone poisoning with iopanoic acid. ( Braverman, LE; Brown, RS; Cohen, JH, 1998)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's4 (22.22)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nygaard, B1
Saedder, EA1
Dalhoff, K1
Wikkelsoe, M1
Jürgens, G1
Calil-Silveira, J1
Serrano-Nascimento, C1
Laconca, RC1
Schmiedecke, L1
Salgueiro, RB1
Kondo, AK1
Nunes, MT1
JACOBZINER, H1
RAYBIN, HW1
de Luis, DA2
Abad, L2
Aller, R2
González-Sagrado, M1
Dueñas, A2
Tunget, CL1
Clark, RF1
Turchen, SG1
Manoguerra, AS1
Matthews, SJ1
Tsuji, H1
Sato, K1
Shimono, J1
Azuma, K1
Hashiguchi, M1
Fujishima, M1
Brown, RS1
Cohen, JH1
Braverman, LE2
Martin, J1
Cuellar, L1
Cavalleri, A1
Roesch, C1
Becker, PG1
Sklar, S1
Azizi, F1
Vagenakis, AG1
Portnay, GI1
Ingbar, SH1
Selye, H5
Solymoss, B1
Gerard, P1
Malvaux, P1
De Visscher, M1
Szabo, S1
Kourounakis, P1

Reviews

3 reviews available for thyroxine and Poisoning

ArticleYear
Levothyroxine Poisoning - Symptoms and Clinical Outcome.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Denmark; Female; Humans; Male; Middle Aged;

2015
[Levothyroxine poisoning: clinical manifestations and therapeutic management].
    Anales de medicina interna (Madrid, Spain : 1984), 2004, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cardiovascular Diseases; Child; Cholestyramine Resi

2004
Acute thyroxine overdosage: two cases of parasuicide.
    The Ulster medical journal, 1993, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Drug Monitoring; Drug Overdose; Electrocardiography; Female; Humans; Ipecac; Pois

1993

Other Studies

15 other studies available for thyroxine and Poisoning

ArticleYear
Underlying Mechanisms of Pituitary-Thyroid Axis Function Disruption by Chronic Iodine Excess in Rats.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:10

    Topics: Animals; Antidotes; Gene Expression Regulation; Iodide Peroxidase; Iodine; Male; Perchlorates; Pitui

2016
Thyroid intoxication.
    New York state journal of medicine, 1958, Feb-01, Volume: 58, Issue:3

    Topics: Child; Humans; Infant; Poisoning; Thyroid Gland; Thyroxine; Triiodothyronine

1958
Raising the decontamination level for thyroid hormone ingestions.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:1

    Topics: Child, Preschool; Emergencies; Humans; Infant; Poisoning; Retrospective Studies; Thyroxine

1995
[Thyroid function in patients with Yusho: 28 year follow-up study].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1997, Volume: 88, Issue:5

    Topics: Aged; Autoantibodies; Female; Follow-Up Studies; Food Contamination; Humans; Middle Aged; Oryza; Pla

1997
Successful treatment of massive acute thyroid hormone poisoning with iopanoic acid.
    The Journal of pediatrics, 1998, Volume: 132, Issue:5

    Topics: Child, Preschool; Contrast Media; Humans; Iopanoic Acid; Male; Poisoning; Thyroid Hormones; Thyroxin

1998
Light symptoms following a high-dose intentional L-thyroxine ingestion treated with cholestyramine.
    Hormone research, 2002, Volume: 57, Issue:1-2

    Topics: Adult; Anion Exchange Resins; Blood Pressure; Cholestyramine Resin; Female; Heart Rate; Humans; Pois

2002
Serum thyroxine in the early diagnosis of carbon disulfide poisoning.
    Archives of environmental health, 1975, Volume: 30, Issue:2

    Topics: Adult; Carbon Disulfide; Cholesterol; Environmental Exposure; Humans; Italy; Middle Aged; Occupation

1975
Management of a child with acute thyroxine ingestion.
    Annals of emergency medicine, 1985, Volume: 14, Issue:11

    Topics: Acute Disease; Emergencies; Humans; Infant; Male; Poisoning; Thyroxine

1985
Thyroxine transport and metabolism in methadone and heroin addicts.
    Annals of internal medicine, 1974, Volume: 80, Issue:2

    Topics: Adult; Biological Transport; Chronic Disease; Female; Humans; Injections, Intravenous; Male; Methado

1974
Protection by catatoxic steroids against meprobamate.
    Neuropharmacology, 1970, Volume: 9, Issue:4

    Topics: Anabolic Agents; Animals; Desoxycorticosterone; Estradiol; Ethylestrenol; Female; Meprobamate; Norst

1970
Protection by catatoxic steroids against cycloheximide intoxication.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Anabolic Agents; Animals; Cycloheximide; Desoxycorticosterone; Estradiol; Ethylestrenol; Female; Nor

1970
Steroids influencing the toxicity of L-tyrosine.
    The Journal of nutrition, 1971, Volume: 101, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Cholesterol; Desoxycorticosterone; Diet; Edema; Ethylestrenol; Eye

1971
Accidental poisoning with thyroid extract treated by exchange transfusion.
    Archives of disease in childhood, 1972, Volume: 47, Issue:256

    Topics: Child, Preschool; Exchange Transfusion, Whole Blood; Female; Humans; Poisoning; Thyroid Hormones; Th

1972
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.
    Neuroendocrinology, 1972, Volume: 9, Issue:5

    Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisonin

1972
Conditioning of catatoxic steroid actions by the thyroid.
    Journal of medicine, 1970, Volume: 1, Issue:1

    Topics: Animals; Ethylestrenol; Female; Poisoning; Rats; Thyroid Gland; Thyroxine

1970
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