Page last updated: 2024-11-06

thyroxine and Placental Abruption

thyroxine has been researched along with Placental Abruption in 6 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"The aims were to establish a gestational-age specific curve for serum total thyroxine (T4) levels and to compare pregnancy outcomes of euthyroid women with those identified to have subclinical hypothyroidism (SCH) defined by an elevated thyroid-stimulating hormone (TSH) level in conjunction with either total T4 or free T4 determinations."7.80Is total thyroxine better than free thyroxine during pregnancy? ( Casey, BM; Cunningham, FG; McIntire, DD; Wilson, KL, 2014)
"The aims were to establish a gestational-age specific curve for serum total thyroxine (T4) levels and to compare pregnancy outcomes of euthyroid women with those identified to have subclinical hypothyroidism (SCH) defined by an elevated thyroid-stimulating hormone (TSH) level in conjunction with either total T4 or free T4 determinations."3.80Is total thyroxine better than free thyroxine during pregnancy? ( Casey, BM; Cunningham, FG; McIntire, DD; Wilson, KL, 2014)
"The 2 reported cases raise the possibility of uteroplacental ischemia and placental abruption being mechanisms by which hypothyroidism can lead to stillbirth; they also highlight the potential of minimizing this risk via adequate levothyroxine treatment from early pregnancy."3.79Optimal treatment of hypothyroidism associated with live birth in cases of previous recurrent placental abruption and stillbirth. ( Chan, SY; Charlesworth, D; Cox, P; Imtiaz, R; Kilby, MD; Vanes, NK, 2013)
" Women with subclinical hypothyroidism (thyroid-stimulating hormone (TSH) values at or above the 98th percentile with a normal free thyroxine (fT4)) or isolated maternal hypothyroxinaemia (fT4 level at or below the second percentile with a normal-range TSH) were compared with biochemically euthyroid controls."3.79Subclinical hypothyroidism as a risk factor for placental abruption: evidence from a low-risk primigravid population. ( Breathnach, FM; Cooley, SM; Donnelly, J; Geary, M; Malone, FD, 2013)
"Pregnancy is a complex state with many endocrinological challenges to a woman's physiology."2.72Understanding the Pathogenesis of Gestational Hypothyroidism. ( Li, X; Mallawa Kankanamalage, O; Zhou, Q, 2021)
"There was a 73% less chance of gestational hypertension for thyroid autoimmune groups."1.62Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4). ( Islam, N; Kiran, Z; Sheikh, A, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Di Girolamo, R1
Liberati, M1
Silvi, C1
D'Antonio, F1
Kiran, Z1
Sheikh, A1
Islam, N1
Mallawa Kankanamalage, O1
Zhou, Q1
Li, X1
Vanes, NK1
Charlesworth, D1
Imtiaz, R1
Cox, P1
Kilby, MD1
Chan, SY1
Breathnach, FM1
Donnelly, J1
Cooley, SM1
Geary, M1
Malone, FD1
Wilson, KL1
Casey, BM1
McIntire, DD1
Cunningham, FG1

Reviews

2 reviews available for thyroxine and Placental Abruption

ArticleYear
Levothyroxine Supplementation in Euthyroid Pregnant Women With Positive Autoantibodies: A Systematic Review and Meta-Analysis.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Abortion, Spontaneous; Abruptio Placentae; Autoantibodies; Dietary Supplements; Female; Humans; Hype

2022
Understanding the Pathogenesis of Gestational Hypothyroidism.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Abortion, Spontaneous; Abruptio Placentae; Animals; Estrogens; Female; Fetal Death; Humans; Hypothyr

2021

Other Studies

4 other studies available for thyroxine and Placental Abruption

ArticleYear
Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4).
    BMC pregnancy and childbirth, 2021, Feb-15, Volume: 21, Issue:1

    Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Apgar Score; Autoantibodies; Autoimmune Diseases;

2021
Optimal treatment of hypothyroidism associated with live birth in cases of previous recurrent placental abruption and stillbirth.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2013, Volume: 123, Issue:3

    Topics: Abruptio Placentae; Adult; Female; Humans; Hypothyroidism; Ischemia; Live Birth; Placenta; Pregnancy

2013
Subclinical hypothyroidism as a risk factor for placental abruption: evidence from a low-risk primigravid population.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2013, Volume: 53, Issue:6

    Topics: Abruptio Placentae; Adult; Antibodies; Asymptomatic Diseases; Case-Control Studies; Female; Gravidit

2013
Is total thyroxine better than free thyroxine during pregnancy?
    American journal of obstetrics and gynecology, 2014, Volume: 211, Issue:2

    Topics: Abruptio Placentae; Adult; Female; Gestational Age; Humans; Hypothyroidism; Pregnancy; Pregnancy Com

2014