Page last updated: 2024-11-06

thyroxine and Pancreatic Neoplasms

thyroxine has been researched along with Pancreatic Neoplasms in 10 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"5% patients had a history of hypothyroidism and all received a replacement hormone therapy with levothyroxine, in particular 20% in metastatic group and 11% in radically resected PDAC patients' group."4.12Should patients on levothyroxine therapy be screened for pancreatic cancer? ( Balsano, R; Coriano', M; Dalla Valle, R; De Lorenzo, S; Del Rio, P; Garajova, I; Gelsomino, F; Leonardi, F; Ravaioli, M; Tovoli, F, 2022)
"Human pancreatic cancer cell (PANC-1 and MPanc96) xenografts were established in nude mice, and the effects of tetrac versus Tetrac NP on tumor growth and tumor angiogenesis were determined."1.39Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles. ( Bharali, DJ; Davis, FB; Davis, PJ; Lin, HY; Meng, R; Mousa, SA; Stain, SC; Sudha, T; Tang, HY; Yalcin, M, 2013)
"Congenital hypothyroidism was diagnosed in related Abyssinian cats."1.28Preliminary studies on congenital hypothyroidism in a family of Abyssinian cats. ( Gruffydd-Jones, TJ; Jones, BR; Lucke, VM; Sparkes, AH, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Garajova, I1
Balsano, R1
Coriano', M1
Gelsomino, F1
Tovoli, F1
De Lorenzo, S1
Del Rio, P1
Dalla Valle, R1
Ravaioli, M1
Leonardi, F1
Strzałka, A1
Hogendorf, P1
Skulimowski, A1
Spychalski, M1
Strzelczyk, J1
Durczynski, A1
Drzayich Antol, D1
Waldman Casebeer, A1
Khoury, R1
Michael, T1
Renda, A1
Hopson, S1
Parikh, A1
Stein, A1
Costantino, M1
Stemkowski, S1
Bunce, M1
Nevo, N1
Abu-Abeid, S1
Hazzan, D1
Lahat, G1
Nachmani, I1
Eldar, SM1
Zhang, L1
Xia, X1
Zhong, Y1
Xie, D1
Liu, S1
Wang, X1
Tu, J1
Faconti, L1
Mills, CE1
Govoni, V1
Gu, H1
Morant, S1
Jiang, B1
Cruickshank, JK1
Webb, AJ1
Lin, J1
Wu, YJ1
Liang, X1
Ji, M1
Ying, HM1
Wang, XY1
Sun, X1
Shao, CH1
Zhan, LX1
Zhang, Y1
Czamara, K1
Karnas, E1
Majka, Z1
Wojcik, T1
Zuba-Surma, EK1
Baranska, M1
Kaczor, A1
Liu, X1
Zhou, F1
Yang, Y1
Wang, W1
Niu, L1
Zuo, D1
Li, X1
Hua, H1
Zhang, B1
Kou, Y1
Guo, J1
Kong, F1
Pan, W1
Gao, D1
Meves, JM1
Sun, H1
Xue, M1
Zhang, Q1
Wang, Y1
Tang, R1
Iso, T1
Haruyama, H1
Sunaga, H1
Matsui, H1
Matsui, M1
Tanaka, R1
Umbarawan, Y1
Syamsunarno, MRAA1
Putri, M1
Yamaguchi, A1
Hanaoka, H1
Negishi, K1
Yokoyama, T1
Kurabayashi, M1
Palomo-Briones, R1
Esquivel-González, S1
Aizpuru, A1
Gómez-Hernández, N1
Casas-Flores, S1
Barba de la Rosa, AP1
Arriaga, S1
Peterson, ME1
Carothers, MA1
Gamble, DA1
Rishniw, M1
Yalcin, M2
Lin, HY2
Sudha, T2
Bharali, DJ2
Meng, R1
Tang, HY1
Davis, FB1
Stain, SC1
Davis, PJ2
Mousa, SA2
Darwish, NH1
Debreli Coskun, M1
Keating, KA1
Murai, H1
Murakami, S1
Ishida, K1
Sugawara, M1
Eriksson, M1
Ajmani, SK1
Mallette, LE1
Jones, BR1
Gruffydd-Jones, TJ1
Sparkes, AH1
Lucke, VM1
Rajatanavin, R1
Liberman, C1
Lawrence, GD1
D'Arcangues, CM1
Young, RA1
Emerson, CH1
Spitsa, AI1
Arkhipenko, VI1

Trials

1 trial available for thyroxine and Pancreatic Neoplasms

ArticleYear
    Journal of patient-reported outcomes, 2018, Volume: 2

    Topics: Adult; Aged; Animals; Astrocytes; Bariatric Surgery; Beta vulgaris; Bioreactors; Biotechnology; Bloo

2018

Other Studies

9 other studies available for thyroxine and Pancreatic Neoplasms

ArticleYear
Should patients on levothyroxine therapy be screened for pancreatic cancer?
    Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6

    Topics: Humans; Hypothyroidism; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Thyroxine

2022
Should patients on levothyroxine therapy be screened for pancreatic cancer?
    Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6

    Topics: Humans; Hypothyroidism; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Thyroxine

2022
Should patients on levothyroxine therapy be screened for pancreatic cancer?
    Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6

    Topics: Humans; Hypothyroidism; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Thyroxine

2022
Should patients on levothyroxine therapy be screened for pancreatic cancer?
    Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6

    Topics: Humans; Hypothyroidism; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Thyroxine

2022
Thyroid hormones concentration in portal and peripheral blood in patients with pancreatic cancer: Preliminary study.
    Cancer biomarkers : section A of Disease markers, 2020, Volume: 29, Issue:3

    Topics: Aged; Biomarkers, Tumor; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged;

2020
Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles.
    Hormones & cancer, 2013, Volume: 4, Issue:3

    Topics: Animals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic

2013
Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug

2017
Elevated serum interleukin-6 and decreased thyroid hormone levels in postoperative patients and effects of IL-6 on thyroid cell function in vitro.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:6

    Topics: Aged; Cholecystectomy; Colorectal Neoplasms; Esophageal Neoplasms; Female; Humans; Interleukin-6; Ma

1996
Hyperthyroidism from thyroid metastasis of pancreatic adenocarcinoma.
    JAMA, 1977, Sep-19, Volume: 238, Issue:12

    Topics: Adenocarcinoma; Humans; Hyperthyroidism; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasm

1977
Preliminary studies on congenital hypothyroidism in a family of Abyssinian cats.
    The Veterinary record, 1992, Aug-15, Volume: 131, Issue:7

    Topics: Animals; Breeding; Carcinoma, Intraductal, Noninfiltrating; Cat Diseases; Cats; Cholesterol; Congeni

1992
Euthyroid hyperthyroxinemia and thyroxine-binding prealbumin excess in islet cell carcinoma.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:1

    Topics: Adenoma, Islet Cell; Aged; Female; Humans; Male; Pancreatic Neoplasms; Prealbumin; Protein Binding;

1985
[The effect of hormones and actinomycin on tumor cell multiplication in in vitro experiments].
    Voprosy onkologii, 1971, Volume: 17, Issue:4

    Topics: Antibiotics, Antineoplastic; Carcinoma; Dactinomycin; Female; Flavonoids; In Vitro Techniques; Insul

1971