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thyroxine and Osteoporotic Fractures

thyroxine has been researched along with Osteoporotic Fractures in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Osteoporotic Fractures: Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.

Research Excerpts

ExcerptRelevanceReference
"This case report describes a 38-year-old woman, who presented with bilateral femoral stress fractures and osteoporosis after years of excessive levothyroxine treatment."7.85Case report: fast reversal of severe osteoporosis after correction of excessive levothyroxine treatment and long-term follow-up. ( Laine, CM; Landin-Wilhelmsen, K, 2017)
"This case report describes a 38-year-old woman, who presented with bilateral femoral stress fractures and osteoporosis after years of excessive levothyroxine treatment."3.85Case report: fast reversal of severe osteoporosis after correction of excessive levothyroxine treatment and long-term follow-up. ( Laine, CM; Landin-Wilhelmsen, K, 2017)
" We aimed to investigate fracture incidence among post-thyroidectomy thyroid cancer patients compared with a matched comparison group, and explore the association between levothyroxine dosage and fracture risk."1.48J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study. ( Lim, H; Park, Y; Shin, DW; Song, SO; Suh, B; Yun, JM, 2018)
"001) between L-T4 dosage and HF/MOF probability on both first and second evaluations was found."1.43Ten-year estimated risk of bone fracture in women with differentiated thyroid cancer under TSH-suppressive levothyroxine therapy. ( Campomenosi, C; Gay, S; Giusti, M; Monti, E; Mortara, L; Paolino, S; Pera, G; Seriolo, B; Vera, L, 2016)
"We report a case of primary empty sella syndrome (ESS) resulting in osteoporotic fractures and persistent non-fusion of the hand epiphyses, and discuss the potential pathogenesis of this disease."1.39Osteoporotic fractures and persistent non-fusion of the hand epiphyses caused by empty sella syndrome in an adult: a case report. ( Chen, Y; He, H; Wang, C; Xu, P; Ye, X; Zhu, Y, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laine, CM1
Landin-Wilhelmsen, K1
Mazziotti, G1
Formenti, AM1
Frara, S1
Olivetti, R1
Banfi, G1
Memo, M1
Maroldi, R1
Giubbini, R1
Giustina, A1
Shin, DW1
Suh, B1
Lim, H1
Yun, JM1
Song, SO1
Park, Y1
Bindl, R1
Oheim, R1
Pogoda, P1
Beil, FT1
Gruchenberg, K1
Reitmaier, S1
Wehner, T1
Calcia, E1
Radermacher, P1
Claes, L1
Amling, M1
Ignatius, A1
Xu, P1
He, H1
Chen, Y1
Wang, C1
Zhu, Y1
Ye, X1
Williams, GR1
Vera, L1
Gay, S1
Campomenosi, C1
Paolino, S1
Pera, G1
Monti, E1
Mortara, L1
Seriolo, B1
Giusti, M1
Segal, E1
Hochberg, I1
Weisman, Y1
Ish-Shalom, S1

Other Studies

8 other studies available for thyroxine and Osteoporotic Fractures

ArticleYear
Case report: fast reversal of severe osteoporosis after correction of excessive levothyroxine treatment and long-term follow-up.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017, Volume: 28, Issue:7

    Topics: Adult; Bone Density; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Femoral

2017
High Prevalence of Radiological Vertebral Fractures in Women on Thyroid-Stimulating Hormone-Suppressive Therapy for Thyroid Carcinoma.
    The Journal of clinical endocrinology and metabolism, 2018, 03-01, Volume: 103, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bone Density; Chemotherapy, Adjuvant; Cross-Sectional Studies; Drug

2018
J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018, Volume: 33, Issue:6

    Topics: Dose-Response Relationship, Drug; Female; Fractures, Bone; Humans; Incidence; Male; Middle Aged; Ost

2018
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD).
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2013, Volume: 31, Issue:11

    Topics: Animals; Disease Models, Animal; Estradiol; Fracture Healing; Hypothalamus; Osteoporotic Fractures;

2013
Osteoporotic fractures and persistent non-fusion of the hand epiphyses caused by empty sella syndrome in an adult: a case report.
    The Journal of international medical research, 2013, Volume: 41, Issue:5

    Topics: Adult; Empty Sella Syndrome; Epiphyses; Humans; Male; Osteoporotic Fractures; Pituitary Gland; Radio

2013
Is prophylactic anti-resorptive therapy required in thyroid cancer patients receiving TSH-suppressive treatment with thyroxine?
    Journal of endocrinological investigation, 2014, Volume: 37, Issue:8

    Topics: Bone and Bones; Bone Density Conservation Agents; Combined Modality Therapy; Dose-Response Relations

2014
Ten-year estimated risk of bone fracture in women with differentiated thyroid cancer under TSH-suppressive levothyroxine therapy.
    Endokrynologia Polska, 2016, Volume: 67, Issue:4

    Topics: Adult; Aged; Female; Humans; Iodine Radioisotopes; Middle Aged; Osteoporotic Fractures; Postoperativ

2016
Severe postpartum osteoporosis with increased PTHrP during lactation in a patient after total thyroidectomy and parathyroidectomy.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011, Volume: 22, Issue:11

    Topics: Absorptiometry, Photon; Adult; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Remo

2011