thyroxine has been researched along with Osteoarthritis, Knee in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous study indicated that the increase of local bio-availability of 3'3'5-triiodothyronine (T3) influenced osteoarthritis (OA) initiation." | 3.91 | Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone. ( Li, L; Li, M; Pang, Y; Wan, Y; Wang, J; Yin, Z; Zhu, C, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohajer, B | 1 |
| Moradi, K | 1 |
| Guermazi, A | 1 |
| Mammen, JSR | 1 |
| Hunter, DJ | 1 |
| Roemer, FW | 1 |
| Demehri, S | 1 |
| Li, L | 1 |
| Li, M | 1 |
| Pang, Y | 1 |
| Wang, J | 1 |
| Wan, Y | 1 |
| Zhu, C | 1 |
| Yin, Z | 1 |
2 other studies available for thyroxine and Osteoarthritis, Knee
| Article | Year |
|---|---|
Levothyroxine use and longitudinal changes in thigh muscles in at-risk participants for knee osteoarthritis: preliminary analysis from Osteoarthritis Initiative cohort.
Topics: Aged; Biomarkers; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Osteoarthritis, Knee; Quadric | 2023 |
Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone.
Topics: Aged; Aged, 80 and over; Animals; Bone and Bones; China; Chondrocytes; Female; Humans; Injections, I | 2019 |