Page last updated: 2024-11-06

thyroxine and Non-alcoholic Fatty Liver Disease

thyroxine has been researched along with Non-alcoholic Fatty Liver Disease in 35 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.

Research Excerpts

ExcerptRelevanceReference
"The association between free triiodothyronine/free thyroxine (FT3/FT4) and non-alcoholic fatty liver disease (NAFLD) in euthyroid subjects is unclear."8.12Mediating effect analysis of visceral adiposity index on free triiodothyronine to free thyroxine ratio and non-alcoholic fatty liver disease in euthyroid population. ( Li, Z; Liu, HX; Ma, HJ; Meng, CQ; Nie, Q; Ren, YY; Yu, CH, 2022)
"Non-alcoholic fatty liver disease (NAFLD) has become a major public health problem concern in recent decades."5.72Serum level of free thyroxine is an independent risk factor for non-alcoholic fatty liver disease in euthyroid people. ( Cheng, Q; Shao, C; Xiang, X; Xu, Y; Zhang, S, 2022)
"NAFLD was diagnosed by ultrasound."5.51Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women. ( Bao, Y; Chen, P; Feng, L; Hou, X; Jia, W; Jiao, L; Wang, H; Wei, L; Zhong, L, 2019)
"NAFLD was defined by using the validated Fatty Liver Index (FLI); FLI≥60 was categorized as NAFLD."5.46Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study. ( Amini, M; Blokzijl, H; Dullaart, RP; Faber, KN; Schreuder, TC; van den Berg, EH; van Tienhoven-Wind, LJ, 2017)
"The relationship between FT4 and NAFLD in women was different according to menopausal status, with negative association in pre-menopausal women (OR: 0."5.42Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects. ( Guan, L; Guan, Q; Jiang, Q; Jiang, Z; Lin, H; Liu, G; Yu, C; Zhang, N; Zhang, X; Zhang, Y; Zheng, X, 2015)
" Hypothyroidism has been identified as a risk factor for NAFLD as thyroxine is required for regulating metabolism in adults."5.41Thyroid Hormone Receptor-β Agonists in NAFLD Therapy: Possibilities and Challenges. ( Li, L; Shi, Y; Song, Y; Sun, L, 2023)
"Overweight/obesity mediated the associations of MAFLD with triiodothyronine (T3), free triiodothyronine (FT3), free thyroxine (FT4), and the mediator accounted for 46."4.31The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes. ( Cao, L; Chen, X; Fan, H; Li, L; Liu, Z; Suo, C; Zhang, T, 2023)
"The association between free triiodothyronine/free thyroxine (FT3/FT4) and non-alcoholic fatty liver disease (NAFLD) in euthyroid subjects is unclear."4.12Mediating effect analysis of visceral adiposity index on free triiodothyronine to free thyroxine ratio and non-alcoholic fatty liver disease in euthyroid population. ( Li, Z; Liu, HX; Ma, HJ; Meng, CQ; Nie, Q; Ren, YY; Yu, CH, 2022)
" Based on their initial serum-free thyroxine (fT4) and thyroid-stimulating hormone (TSH) levels, they were classified into control, subclinical hypothyroidism (TSH >4."3.81Impact of hypothyroidism on the development of non-alcoholic fatty liver disease: A 4-year retrospective cohort study. ( Bang, KB; Cho, YK; Kwon, HJ; Lee, KW; Lee, MY; Rhee, EJ, 2015)
"Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with type 2 diabetes mellitus (T2DM) and associated with significant morbidity and mortality."2.87Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD. ( Angus, PW; Bee, YM; Bruinstroop, E; Burrell, LM; Cao, Y; Chandran, K; Cho, LW; Dalan, R; Leow, MKS; Leung, C; Lim, SC; Michael, N; Patel, SK; Sadananthan, SA; Sinha, RA; Soh, SB; Stapleton, HM; Sum, CF; Teo, EK; Toh, SA; Velan, SS; Yen, PM, 2018)
"Non-alcoholic fatty liver disease (NAFLD) has become a major public health problem concern in recent decades."1.72Serum level of free thyroxine is an independent risk factor for non-alcoholic fatty liver disease in euthyroid people. ( Cheng, Q; Shao, C; Xiang, X; Xu, Y; Zhang, S, 2022)
"In subjects with liver fibrosis, other cause of liver fibrosis were ruled out."1.72Liver Stiffness in Obese Hypothyroid Patients Taking Levothyroxine. ( Arturi, F; Aversa, A; Brunetti, A; Mazza, E; Montalcini, T; Perticone, M; Pujia, A; Pujia, R; Romeo, S; Sciacqua, A, 2022)
"In sufferers with nonalcoholic fatty liver disease (NAFLD), the differences of thyroid associated hormones and neutrophil to lymphocyte ratio (NLR) in different liver pathological groups have been compared."1.72Clinical value of thyroid related hormones combined with neutrophil to lymphocyte ratio in patients with nonalcoholic fatty liver disease. ( Chu, W; Feng, J; Li, P; Liu, L; Liu, Y; Mi, Y; Niu, B; Wu, X; Zhang, P, 2022)
"The incidence rate of NAFLD was 85."1.72High-Normal Thyroid Function Predicts Incident Nonalcoholic Fatty Liver Disease Among Middle-Aged and Older Euthyroid Subjects. ( Gu, Y; Jia, Q; Liu, L; Meng, G; Niu, K; Song, K; Sun, S; Wang, X; Wang, Y; Wu, H; Wu, X; Zhang, Q; Zhang, S; Zhang, T; Zhou, M, 2022)
"Thyroid function and type 2 diabetes mellitus (T2DM) are both associated with increased risks of adverse clinical outcomes in nonalcoholic fatty liver disease (NAFLD)."1.56Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. ( Huang, B; Yang, S; Ye, S, 2020)
"Serum FT3 levels in subjects with NAFLD were significantly reduced, while TSH was increased compared to that in controls."1.56Serum Thyroid Hormones Levels are Significantly Associated with Nonalcoholic Fatty Liver Disease in Euthyroid Chinese Population. ( Dai, Y; Qin, J; Zhang, J; Zhang, X, 2020)
"The major outcome was the occurrence of NAFLD, diagnosed based on the findings of abdominal ultrasonography."1.51The relationship between nonalcoholic fatty liver disease and pediatric congenital hypothyroidism patients. ( Chen, MY; Chen, SY; Chou, YY; Pan, YW; Tsai, MC; Yang, YJ, 2019)
"NAFLD was diagnosed by ultrasound."1.51Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women. ( Bao, Y; Chen, P; Feng, L; Hou, X; Jia, W; Jiao, L; Wang, H; Wei, L; Zhong, L, 2019)
"In murine models of advanced nonalcoholic steatohepatitis (NASH), the administration of T3 reduced liver triglyceride, repressed liver inflammation, and attenuated injury."1.51Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis. ( Bechmann, L; Best, J; Canbay, A; Claridge, LC; Coombes, JD; Gerken, G; Manka, P; Moeller, L; Sydor, S; Syn, WK; Wedemeyer, H, 2019)
"NAFLD was defined by using the validated Fatty Liver Index (FLI); FLI≥60 was categorized as NAFLD."1.46Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study. ( Amini, M; Blokzijl, H; Dullaart, RP; Faber, KN; Schreuder, TC; van den Berg, EH; van Tienhoven-Wind, LJ, 2017)
"Hypothyroidism was considered at a thyroid stimulating hormone level ≥ 4."1.43FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. ( Ahbab, S; Ataoğlu, HE; Çetin, F; Gökmen, FY; Mamaç, RY; Türker, BÇ; Türker, F; Yenigün, M, 2016)
"Subjects with NAFLD had significantly higher TSH levels and lower FT4 levels than those without NAFLD (p < 0."1.42Thyroid function is associated with non-alcoholic fatty liver disease in euthyroid subjects. ( Gu, H; Sui, J; Tao, Y; Wu, J, 2015)
"The relationship between FT4 and NAFLD in women was different according to menopausal status, with negative association in pre-menopausal women (OR: 0."1.42Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects. ( Guan, L; Guan, Q; Jiang, Q; Jiang, Z; Lin, H; Liu, G; Yu, C; Zhang, N; Zhang, X; Zhang, Y; Zheng, X, 2015)
"Non-alcoholic fatty liver disease (NAFLD) is one of the most common disorders of the liver worldwide."1.42Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years. ( Boehm, BO; Denzer, C; Graeter, T; Greinert, A; Haenle, MM; Holzner, D; Koenig, W; Kratzer, W; Ludwig, U; Mason, RA; Oeztuerk, S, 2015)
"NAFLD was diagnosed by conventional ultrasound examination."1.40Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease. ( Aydın, S; Cesur, Y; Gökçe, S; Özgen, IT; Torun, E, 2014)
"NAFLD and non-NAFLD groups had slightly higher fasting blood glucose values than the control group."1.40Thyroid function in obese children with non-alcoholic fatty liver disease. ( Bilgin, H; Pirgon, Ö, 2014)
"NAFLD was significantly associated with hypothyroidism (30."1.38Non-alcoholic fatty liver disease across the spectrum of hypothyroidism. ( Chung, GE; Kim, D; Kim, W; Kim, YJ; Lee, HS; Park, MJ; Yim, JY; Yoon, JH, 2012)
"Patients with NAFLD had significantly lower levels of serum-free thyroxine (FT4) than controls (11·12 ± 1·43 vs 11·58 ± 1·47 pmol/l; P < 0·001)."1.37Association between thyroid function and nonalcoholic fatty liver disease in euthyroid elderly Chinese. ( Li, Y; Miao, M; Xu, C; Xu, L; Yu, C, 2011)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (54.29)24.3611
2020's16 (45.71)2.80

Authors

AuthorsStudies
Shao, C1
Cheng, Q1
Zhang, S2
Xiang, X2
Xu, Y2
Zhang, Y5
Li, J1
Liu, H1
Fan, H2
Liu, Z2
Zhang, X5
Wu, S1
Shi, T1
Zhang, P2
Chen, X3
Zhang, T3
Pujia, R1
Mazza, E1
Montalcini, T1
Arturi, F1
Brunetti, A1
Aversa, A1
Romeo, S1
Perticone, M1
Sciacqua, A1
Pujia, A1
Liu, HX1
Ren, YY1
Meng, CQ1
Li, Z2
Nie, Q1
Yu, CH1
Ma, HJ1
Li, L3
Cao, L1
Suo, C1
Li, P1
Liu, L4
Niu, B1
Mi, Y1
Liu, Y1
Feng, J1
Wu, X2
Chu, W1
Chen, YL1
Tian, S1
Wu, J3
Li, H3
Li, S1
Xu, Z2
Liang, XY1
Adhikari, VP1
Xiao, J1
Song, JY1
Ma, CY1
She, RL1
Li, ZX1
Wu, KN1
Kong, LQ1
Song, Y1
Shi, Y1
Sun, L1
Hu, Y1
Zhou, F1
Lei, F1
Lin, L1
Huang, X1
Sun, T1
Liu, W1
Cai, J1
She, ZG1
Wan, H1
Yu, G1
Xu, S1
Jiang, Y1
Duan, H1
Lin, X1
Ma, Q1
Wang, D1
Liang, Y1
Shen, J1
Nikolaou, M1
Vasilakis, IA1
Marinakis, NM1
Tilemis, FN1
Zellos, A1
Lykopoulou, E1
Traeger-Synodinos, J1
Kanaka-Gantenbein, C1
Pan, YW1
Tsai, MC1
Yang, YJ1
Chen, MY1
Chen, SY1
Chou, YY1
Huang, B1
Yang, S1
Ye, S1
Zhang, J2
Dai, Y1
Qin, J1
Gu, Y1
Zhang, Q2
Meng, G1
Wu, H1
Wang, Y4
Wang, X2
Sun, S1
Zhou, M1
Jia, Q1
Song, K1
Niu, K1
Quirós-González, V1
Rubio, R1
Pulido, F1
Rial-Crestelo, D1
Martín-Jurado, C1
Hernández-Ros, MÁ1
López-Jiménez, EA1
Ferrari, JM1
Caro-Teller, JM1
Pinar, Ó1
Pedrera-Jiménez, M1
García-Barrio, N1
Serrano, P1
Bernal, JL1
Tanguay, P1
Décary, S1
Martineau-Roy, J1
Gravel, EM1
Gervais, I1
St-Jean, P1
Tousignant, M1
Marquis, N1
Qian, L1
Xuemei, L1
Jitao, L1
Yun'Ai, S1
Tianmei, S1
da Silva, HS1
Nakamura, FY1
Papoti, M1
da Silva, AS1
Dos-Santos, JW1
Huth, SF1
Cho, SM1
Robba, C1
Highton, D1
Battaglini, D1
Bellapart, J1
Suen, JY1
Li Bassi, G1
Taccone, FS1
Arora, RC1
Whitman, G1
Fraser, JF1
Fanning, JP1
Yang, B1
Dmytriw, AA1
Wang, T1
Luo, J1
Li, Y2
Ma, Y1
Chen, J1
Gao, P1
Feng, Y1
Bai, X1
Dong, J1
Yang, R1
Jiao, L2
Ling, F1
Ding, Y1
Chen, Z1
Pan, Y1
Wang, J1
Meng, X1
Lin, J1
Jing, J1
Xie, X1
Lwi, SJ1
Herron, TJ1
Curran, BC1
Ivanova, MV1
Schendel, K1
Dronkers, NF1
Baldo, JV1
Yi, X1
Yang, Y1
Zhao, Z2
Xu, M1
Sheng, Y1
Tian, J1
Hua, W1
Peng, Y1
Han, Z1
Li, T2
Yin, C1
Wang, S1
Nan, G1
Yang, H1
Zhou, B1
Cai, Y1
Li, G1
Peng, X1
Guan, S1
Zhou, J1
Ye, M1
Wang, L1
Zhang, L1
Hong, B1
Wan, J1
Zhu, Q1
Liu, J1
Yang, P1
Guido, CA1
Loffredo, L1
Zicari, AM1
Pavone, P1
Savasta, S1
Gagliano, A1
Brindisi, G1
Galardini, G1
Bertolini, A1
Spalice, A1
Zheng, S1
Wang, H2
Chen, G1
Shangguan, H1
Yu, L1
Lin, Z1
Lin, Y1
Yao, P1
Kang, D1
Guo, W1
Qin, P1
Li, XN1
Lu, J1
Zhu, WF1
Diao, QQ1
Xu, NZ1
Machlab, S1
Miquel, M1
Voltà, T1
Escoda, MR1
Vergara, M1
Bruinstroop, E1
Dalan, R1
Cao, Y1
Bee, YM1
Chandran, K1
Cho, LW1
Soh, SB1
Teo, EK1
Toh, SA1
Leow, MKS1
Sinha, RA1
Sadananthan, SA1
Michael, N1
Stapleton, HM1
Leung, C1
Angus, PW1
Patel, SK1
Burrell, LM1
Lim, SC1
Sum, CF1
Velan, SS1
Yen, PM1
Chen, P1
Hou, X1
Wei, L1
Feng, L1
Zhong, L1
Bao, Y1
Jia, W1
Patel, VJ1
Joharapurkar, AA1
Kshirsagar, SG1
Sutariya, BK1
Patel, MS1
Bahekar, RH1
Jain, MR1
Manka, P1
Bechmann, L1
Best, J1
Sydor, S1
Claridge, LC1
Coombes, JD1
Canbay, A1
Moeller, L1
Gerken, G1
Wedemeyer, H1
Syn, WK1
Torun, E1
Özgen, IT1
Gökçe, S1
Aydın, S1
Cesur, Y1
Bilgin, H1
Pirgon, Ö1
Tao, Y1
Gu, H1
Sui, J1
Liu, G1
Zheng, X1
Guan, L1
Jiang, Z1
Lin, H1
Jiang, Q1
Zhang, N1
Yu, C2
Guan, Q1
van Tienhoven-Wind, LJ2
Dullaart, RP2
Ludwig, U1
Holzner, D1
Denzer, C1
Greinert, A1
Haenle, MM1
Oeztuerk, S1
Koenig, W1
Boehm, BO1
Mason, RA1
Kratzer, W1
Graeter, T1
Lee, KW1
Bang, KB1
Rhee, EJ1
Kwon, HJ1
Lee, MY1
Cho, YK1
Gökmen, FY1
Ahbab, S1
Ataoğlu, HE1
Türker, BÇ1
Çetin, F1
Türker, F1
Mamaç, RY1
Yenigün, M1
Geach, T1
van den Berg, EH1
Amini, M1
Schreuder, TC1
Faber, KN1
Blokzijl, H1
Xu, C1
Xu, L1
Miao, M1
Walsh, JP1
Chung, GE1
Kim, D1
Kim, W1
Yim, JY1
Park, MJ1
Kim, YJ1
Yoon, JH1
Lee, HS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of 4-month Therapy of Levothyroxine on Non-Alcoholic Fatty Liver Disease (NAFLD) and Diabetes Control in Diabetic Patients[NCT03281083]Phase 229 participants (Actual)Interventional2014-03-28Terminated (stopped due to Difficult recruitment and end of funding.)
Early Predictors of NAFLD in Patient of Hypothyroidism[NCT05813301]100 participants (Anticipated)Observational2023-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for thyroxine and Non-alcoholic Fatty Liver Disease

ArticleYear
Thyroid Hormone Receptor-β Agonists in NAFLD Therapy: Possibilities and Challenges.
    The Journal of clinical endocrinology and metabolism, 2023, Jun-16, Volume: 108, Issue:7

    Topics: Animals; Humans; Hypothyroidism; Mice; Non-alcoholic Fatty Liver Disease; Receptors, Thyroid Hormone

2023
Hepatomegaly and fatty liver disease secondary to central hypothyroidism in combination with macrosomia as initial presentation of IGSF1 deficiency syndrome.
    Hormones (Athens, Greece), 2023, Volume: 22, Issue:3

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Macrosomia; Hepatomegaly; Humans; Immunoglobulins; I

2023
    Enfermedades infecciosas y microbiologia clinica, 2023, Volume: 41, Issue:3

    Topics: Adult; China; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver D

2023
Low-normal thyroid function and the pathogenesis of common cardio-metabolic disorders.
    European journal of clinical investigation, 2015, Volume: 45, Issue:5

    Topics: Asymptomatic Diseases; Cardiovascular Diseases; Cholesterol, LDL; Humans; Hypothyroidism; Insulin Re

2015

Trials

1 trial available for thyroxine and Non-alcoholic Fatty Liver Disease

ArticleYear
Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD.
    The Journal of clinical endocrinology and metabolism, 2018, 07-01, Volume: 103, Issue:7

    Topics: Adult; Diabetes Mellitus, Type 2; Humans; Lipids; Liver; Male; Middle Aged; Non-alcoholic Fatty Live

2018

Other Studies

30 other studies available for thyroxine and Non-alcoholic Fatty Liver Disease

ArticleYear
Serum level of free thyroxine is an independent risk factor for non-alcoholic fatty liver disease in euthyroid people.
    Annals of palliative medicine, 2022, Volume: 11, Issue:2

    Topics: Cross-Sectional Studies; Female; Humans; Male; Non-alcoholic Fatty Liver Disease; Retrospective Stud

2022
Correlation between the thyroid hormone levels and nonalcoholic fatty liver disease in type 2 diabetic patients with normal thyroid function.
    BMC endocrine disorders, 2022, May-31, Volume: 22, Issue:1

    Topics: Diabetes Mellitus, Type 2; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Retrospective

2022
Thyroid Stimulating Hormone Levels Are Associated With Genetically Predicted Nonalcoholic Fatty Liver Disease.
    The Journal of clinical endocrinology and metabolism, 2022, 08-18, Volume: 107, Issue:9

    Topics: Humans; Mendelian Randomization Analysis; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Thyr

2022
Liver Stiffness in Obese Hypothyroid Patients Taking Levothyroxine.
    Medicina (Kaunas, Lithuania), 2022, Jul-18, Volume: 58, Issue:7

    Topics: Cross-Sectional Studies; Humans; Hypothyroidism; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver D

2022
Mediating effect analysis of visceral adiposity index on free triiodothyronine to free thyroxine ratio and non-alcoholic fatty liver disease in euthyroid population.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adiposity; Cross-Sectional Studies; Humans; Non-alcoholic Fatty Liver Disease; Risk Factors; Thyroxi

2022
The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2023, Volume: 55, Issue:6

    Topics: Humans; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity; Overweight; Thyroid Hormones

2023
Clinical value of thyroid related hormones combined with neutrophil to lymphocyte ratio in patients with nonalcoholic fatty liver disease.
    Medicine, 2022, Dec-23, Volume: 101, Issue:51

    Topics: Fibrosis; Humans; Lymphocytes; Neutrophils; Non-alcoholic Fatty Liver Disease; Thyroid Gland; Thyroi

2022
Impact of Thyroid Function on the Prevalence and Mortality of Metabolic Dysfunction-Associated Fatty Liver Disease.
    The Journal of clinical endocrinology and metabolism, 2023, Jun-16, Volume: 108, Issue:7

    Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Non-alcoholic Fatty Liver Disease; Nutrition Survey

2023
The nonlinear relationship between thyroid function parameters and metabolic dysfunction-associated fatty liver disease.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Cross-Sectional Studies; Humans; Non-alcoholic Fatty Liver Disease; Retrospective Studies; Thyroid G

2023
Central Sensitivity to Free Triiodothyronine With MAFLD and Its Progression to Liver Fibrosis in Euthyroid Adults.
    The Journal of clinical endocrinology and metabolism, 2023, 08-18, Volume: 108, Issue:9

    Topics: Adult; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Prospective Studies; Risk Factors

2023
The relationship between nonalcoholic fatty liver disease and pediatric congenital hypothyroidism patients.
    The Kaohsiung journal of medical sciences, 2019, Volume: 35, Issue:12

    Topics: Adolescent; Adult; Blood Glucose; Child; Congenital Hypothyroidism; Cross-Sectional Studies; Female;

2019
Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients.
    Journal of diabetes research, 2020, Volume: 2020

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Middle Aged; Non-a

2020
Serum Thyroid Hormones Levels are Significantly Associated with Nonalcoholic Fatty Liver Disease in Euthyroid Chinese Population.
    Clinical laboratory, 2020, Oct-01, Volume: 66, Issue:10

    Topics: China; Cross-Sectional Studies; Humans; Non-alcoholic Fatty Liver Disease; Retrospective Studies; Ri

2020
High-Normal Thyroid Function Predicts Incident Nonalcoholic Fatty Liver Disease Among Middle-Aged and Older Euthyroid Subjects.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2022, 01-07, Volume: 77, Issue:1

    Topics: Aged; Cohort Studies; Humans; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; T

2022
Turner syndrome as a cause of liver cirrhosis.
    Gastroenterologia y hepatologia, 2018, Volume: 41, Issue:5

    Topics: Estrogens; Female; Gilbert Disease; Hashimoto Disease; Hormone Replacement Therapy; Human Growth Hor

2018
Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women.
    European journal of clinical investigation, 2019, Volume: 49, Issue:4

    Topics: Alanine Transaminase; Cross-Sectional Studies; Disease Progression; Female; Humans; Liver Cirrhosis,

2019
Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone.
    Current molecular pharmacology, 2019, Volume: 12, Issue:2

    Topics: Animals; Bile; Diet, High-Fat; Glucagon-Like Peptide 1; Liver; Male; Methimazole; Mice; Mice, Inbred

2019
Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:8

    Topics: Biomarkers; Down-Regulation; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty

2019
Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease.
    Journal of clinical research in pediatric endocrinology, 2014, Volume: 6, Issue:1

    Topics: Adolescent; Anthropometry; Biomarkers; Case-Control Studies; Child; Fatty Liver; Female; Follow-Up S

2014
Thyroid function in obese children with non-alcoholic fatty liver disease.
    Journal of clinical research in pediatric endocrinology, 2014, Volume: 6, Issue:3

    Topics: Adolescent; Biomarkers; Blood Glucose; Case-Control Studies; Child; Female; Humans; Insulin; Insulin

2014
Thyroid function is associated with non-alcoholic fatty liver disease in euthyroid subjects.
    Endocrine research, 2015, Volume: 40, Issue:2

    Topics: Adult; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Non-alcoholic

2015
Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects.
    Endocrine research, 2015, Volume: 40, Issue:4

    Topics: Adult; China; Comorbidity; Female; Humans; Male; Menopause; Metabolic Syndrome; Middle Aged; Non-alc

2015
Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years.
    BMC endocrine disorders, 2015, Aug-15, Volume: 15

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cross-Secti

2015
Impact of hypothyroidism on the development of non-alcoholic fatty liver disease: A 4-year retrospective cohort study.
    Clinical and molecular hepatology, 2015, Volume: 21, Issue:4

    Topics: Adult; Aged; Cohort Studies; Female; Follow-Up Studies; Humans; Hypothyroidism; Incidence; Kaplan-Me

2015
FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism.
    Clinics (Sao Paulo, Brazil), 2016, Volume: 71, Issue:4

    Topics: Adult; Biomarkers; Cholesterol; Female; Humans; Hypothyroidism; Insulin Resistance; Male; Metabolic

2016
Thyroid function: Poor thyroid function linked to NAFLD.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:8

    Topics: Fatty Liver; Humans; Non-alcoholic Fatty Liver Disease; Thyroid Function Tests; Thyroid Gland; Thyro

2016
Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study.
    Metabolism: clinical and experimental, 2017, Volume: 67

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Female; Humans;

2017
Association between thyroid function and nonalcoholic fatty liver disease in euthyroid elderly Chinese.
    Clinical endocrinology, 2011, Volume: 75, Issue:2

    Topics: Aged; Asian People; Body Mass Index; Cross-Sectional Studies; Fatty Liver; Humans; Non-alcoholic Fat

2011
Setpoints and susceptibility: do small differences in thyroid function really matter?
    Clinical endocrinology, 2011, Volume: 75, Issue:2

    Topics: Fatty Liver; Humans; Non-alcoholic Fatty Liver Disease; Thyroid Gland; Thyroxine

2011
Non-alcoholic fatty liver disease across the spectrum of hypothyroidism.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Adult; Alanine Transaminase; Body Mass Index; Cross-Sectional Studies; Fatty Liver; Female; Humans;

2012