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thyroxine and Nerve Degeneration

thyroxine has been researched along with Nerve Degeneration in 7 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"02% methimazole (MMI) (w/v) in drinking water, while the experimental hyperthyroidism group is performed by exogenous T4 [from 50 to 200microg/kg body weight intragastric administration beside adding 0."3.76Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats. ( Ahmed, RG; El-Bakry, AM; El-Gareib, AW, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianco, AC1
Kim, BS1
El-Bakry, AM1
El-Gareib, AW1
Ahmed, RG1
Bijlsma, WA1
Jennekens, FG1
Schotman, P1
Gispen, WH1
Mattos, VM1
de Mattos, JP1
Lucca, I1
Giorelli, PC1
Hanson, MG1
Shen, S1
Wiemelt, AP1
McMorris, FA1
Barres, BA1
den Jager Hartog, WA1
de Jong, JM1
Vianney de Jong, JM1
Schoot, JB1
Silverman, AJ1
Knigge, KM1
Ribas, JL1
Sheridan, MN1

Reviews

2 reviews available for thyroxine and Nerve Degeneration

ArticleYear
Pathophysiological relevance of deiodinase polymorphism.
    Current opinion in endocrinology, diabetes, and obesity, 2018, Volume: 25, Issue:5

    Topics: Brain Diseases, Metabolic; Endocrine System Diseases; Humans; Hypothyroidism; Iodide Peroxidase; Iod

2018
Neurotrophic factors and regeneration in the peripheral nervous system.
    Psychoneuroendocrinology, 1984, Volume: 9, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Cyclic AMP; Cyclophosphamide; Gangliosides; Goldfish; Nerve De

1984

Other Studies

5 other studies available for thyroxine and Nerve Degeneration

ArticleYear
Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2010, Volume: 28, Issue:5

    Topics: Animals; Antithyroid Agents; Brain; Cell Differentiation; Disease Models, Animal; Female; Humans; Hy

2010
[Polyneuropathy in the course of hyperthyroidism: report of a case].
    Arquivos de neuro-psiquiatria, 1984, Volume: 42, Issue:3

    Topics: Adult; Female; Humans; Hyperthyroidism; Muscular Atrophy; Nerve Degeneration; Peripheral Nervous Sys

1984
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Morphogenetic Proteins; Brain-Derived Neurotrophic Factor

1998
Muscle and central nervous system metamorphosis. Histology and autoradiography.
    Archives of neurology, 1973, Volume: 28, Issue:3

    Topics: Animals; Anura; Autoradiography; Blood-Brain Barrier; Brain; Central Nervous System; Iodides; Metamo

1973
Transport capacity of median eminence. 3. Amino acid and thyroxine transport of organ-cultured median eminence.
    Neuroendocrinology, 1973, Volume: 11, Issue:2

    Topics: Amino Acids; Aminobutyrates; Animals; Catecholamines; Cerebral Ventricles; Ependyma; Microscopy, Ele

1973