thyroxine has been researched along with Necrosis in 35 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease." | 7.79 | An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013) |
| "A 54-year-old hypothyroid male taking thyroxine and simvastatin presented with bilateral leg compartment syndrome and myonecrosis." | 7.74 | Simvastatin-induced bilateral leg compartment syndrome and myonecrosis associated with hypothyroidism. ( Andrews, B; Ramdass, MJ; Singh, G, 2007) |
| " The aim of the present study was to determine the effects of triiodothyronine (T3) treatment on cut-surface healing of remnant stomach with weight loss alterations after sleeve gastrectomy (SG)." | 3.88 | Effects of Thyroid Hormone Therapy on Cut-Surface Healing of the Remnant Stomach with Short-Term Weight Loss Alterations after Sleeve Gastrectomy. ( Basok, BI; Bostanci, EB; Ceyran, AB; Karaman, K; Kisa, U; Orman, S, 2018) |
| "We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease." | 3.79 | An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013) |
| "A 54-year-old hypothyroid male taking thyroxine and simvastatin presented with bilateral leg compartment syndrome and myonecrosis." | 3.74 | Simvastatin-induced bilateral leg compartment syndrome and myonecrosis associated with hypothyroidism. ( Andrews, B; Ramdass, MJ; Singh, G, 2007) |
| "Cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta." | 3.66 | The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. ( Cameron, AJ; Revis, NW, 1978) |
| "Hypothyroidism was subsequently diagnosed." | 1.62 | Acute Hepatopathy in a Dog Secondary to Hypothyroidism-Induced Atherosclerotic Infarction and Necrosis. ( Bolton, TA, 2021) |
| "Mercuric chloride (HgCl2) is a well-known renal toxic that causes acute renal failure." | 1.29 | Is the increase in renal papillary phospholipid biosynthesis a protective mechanism against injury? ( Arrizurieta, E; Fernández-Tomé, MD; Negri, A; Scerbo, A; Setton-Avruj, CP; Sterin-Speziale, NB, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (45.71) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 5 (14.29) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Karakus, OO | 1 |
| Godugu, K | 1 |
| Rajabi, M | 1 |
| Mousa, SA | 1 |
| Bolton, TA | 1 |
| Orman, S | 1 |
| Karaman, K | 1 |
| Basok, BI | 1 |
| Kisa, U | 1 |
| Ceyran, AB | 1 |
| Bostanci, EB | 1 |
| Kang, P | 1 |
| Yao, Y | 1 |
| Yang, J | 1 |
| Shen, B | 1 |
| Zhou, Z | 1 |
| Pei, F | 1 |
| Gorodetskaia, IV | 1 |
| Gusakova, EA | 1 |
| Ellett, JD | 1 |
| Evans, ZP | 1 |
| Fiorini, JH | 1 |
| Fiorini, RN | 1 |
| Haines, JK | 1 |
| Schmidt, MG | 1 |
| Chavin, KD | 1 |
| Wang, YY | 1 |
| Jiao, B | 1 |
| Guo, WG | 1 |
| Che, HL | 1 |
| Yu, ZB | 1 |
| Kasherman, L | 1 |
| Foy, A | 1 |
| Tierney, A | 1 |
| Reeves, GE | 1 |
| Tran, HA | 1 |
| Haas, MJ | 1 |
| Parseghian, SA | 1 |
| Sajid, RM | 1 |
| Mooradian, AD | 1 |
| RAAB, W | 1 |
| Rollins, G | 1 |
| Rana, SV | 1 |
| Allen, T | 1 |
| Ramdass, MJ | 1 |
| Singh, G | 1 |
| Andrews, B | 1 |
| Samuels, MA | 1 |
| Benvenga, S | 1 |
| Granata, A | 1 |
| Trimarchi, F | 1 |
| Robert, V | 1 |
| Silvestre, JS | 1 |
| Charlemagne, D | 1 |
| Sabri, A | 1 |
| Trouvé, P | 1 |
| Wassef, M | 1 |
| Swynghedauw, B | 1 |
| Delcayre, C | 1 |
| Sato, K | 1 |
| Toraya, S | 1 |
| Shiratori, K | 1 |
| Kasagi, Y | 1 |
| Mandai, Y | 1 |
| Miyamoto, T | 1 |
| Fukuda, I | 1 |
| Kasono, K | 1 |
| Demura, H | 1 |
| Obara, T | 1 |
| Schlenker, EH | 1 |
| Burbach, JA | 1 |
| Yamamoto, R | 1 |
| Oda, M | 1 |
| Yamamoto, T | 1 |
| Nishizawa, Y | 1 |
| Tsuji, M | 1 |
| Terada, N | 1 |
| Setton-Avruj, CP | 1 |
| Fernández-Tomé, MD | 1 |
| Negri, A | 1 |
| Scerbo, A | 1 |
| Arrizurieta, E | 1 |
| Sterin-Speziale, NB | 1 |
| Li, J | 1 |
| French, BA | 1 |
| Fu, P | 1 |
| French, SW | 1 |
| Britton, RS | 1 |
| Koves, G | 1 |
| Orrego, H | 1 |
| Kalant, H | 1 |
| Phillips, MJ | 1 |
| Khanna, JM | 1 |
| Israel, Y | 1 |
| Revis, NW | 1 |
| Cameron, AJ | 1 |
| Chomette, G | 1 |
| Auriol, M | 1 |
| Brohon, J | 1 |
| Sterne, J | 1 |
| Pagliacci, MC | 1 |
| Pelicci, G | 1 |
| Francisci, D | 1 |
| Giammartino, C | 1 |
| Fedeli, L | 1 |
| Stagni, G | 1 |
| Nicoletti, I | 1 |
| Dardik, H | 1 |
| Dardik, I | 1 |
| Smith, IB | 1 |
| Mitsudo, S | 1 |
| Sherman, A | 1 |
| Gliedman, ML | 1 |
| Lee, HJ | 1 |
| Lee, YB | 1 |
| Kim, DS | 1 |
| Bouhour, JB | 1 |
| Nicolas, G | 1 |
| Daniel, M | 1 |
| Le Bodic, MF | 1 |
| Godin, JF | 1 |
| Fontaine, R | 1 |
| Bollack, C | 1 |
| Ceylan, I | 1 |
| Mack, G | 1 |
| Savoie, LL | 1 |
| Dumlao, JS | 1 |
| Taylor, AL | 1 |
| Finster, JL | 1 |
| Raskin, P | 1 |
| Field, JB | 1 |
| Mintz, DH | 1 |
| Mikulicich, GF | 1 |
| Oester, TY | 1 |
| Srinivasan, S | 1 |
| Srinivasan, U | 1 |
| Balwani, H | 1 |
| Johansson, H | 1 |
| Jönsson, LE | 1 |
2 reviews available for thyroxine and Necrosis
| Article | Year |
|---|---|
NEUROGENIC MULTIFOCAL DESTRUCTION OF MYOCARDIAL TISSUE (PATHOGENIC MECHANISM AND ITS PREVENTION).
Topics: Adrenal Cortex Hormones; Catecholamines; Epinephrine; Heart Diseases; Hypoxia; Myocardial Infarction | 1963 |
The brain-heart connection.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Catecholamines; Cats; Culture; Death, Su | 2007 |
33 other studies available for thyroxine and Necrosis
| Article | Year |
|---|---|
Dual Targeting of Norepinephrine Transporter (NET) Function and Thyrointegrin αvβ3 Receptors in the Treatment of Neuroblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug S | 2020 |
Acute Hepatopathy in a Dog Secondary to Hypothyroidism-Induced Atherosclerotic Infarction and Necrosis.
Topics: Animals; Atherosclerosis; Dog Diseases; Dogs; Hepatic Infarction; Hypothyroidism; Liver Diseases; Ma | 2021 |
Effects of Thyroid Hormone Therapy on Cut-Surface Healing of the Remnant Stomach with Short-Term Weight Loss Alterations after Sleeve Gastrectomy.
Topics: Animals; Bariatric Surgery; Gastrectomy; Gastric Stump; Male; Models, Animal; Necrosis; Obesity, Mor | 2018 |
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Pro | 2013 |
[Effect of iodine-containing thyroid hormones on the histostructure of rat liver under the stress].
Topics: Animals; Animals, Outbred Strains; Antithyroid Agents; Hepatocytes; Liver; Liver Circulation; Male; | 2014 |
The use of the Papworth cocktail is detrimental to steatotic livers after ischemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Fatty Liver; Liver; Liver Transplantation; Ma | 2008 |
Excessive thyroxine enhances susceptibility to apoptosis and decreases contractility of cardiomyocytes.
Topics: Animals; Apoptosis; Cell Separation; Cell Size; Cells, Cultured; DNA Fragmentation; Heart Rate; Hype | 2010 |
Primary hypothyroidism masquerading as hepatocellular necrosis.
Topics: Diagnosis, Differential; End Stage Liver Disease; Female; Hormone Replacement Therapy; Humans; Hypot | 2015 |
Effect of thyroid hormone responsive protein (THRP) expression on PC12 cell survival.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Cycle; Cell Death; Cell Survival; DNA | 2003 |
New treatment for thyroid ablation as effective as traditional therapy without side-effects of hypothyroidism.
Topics: Glycoprotein Hormones, alpha Subunit; Humans; Hypothyroidism; Iodine Radioisotopes; Necrosis; Postop | 2004 |
Influence of thyroxine and n-propylthiouracil on nephro-toxicity of inorganic arsenic in rat.
Topics: Animals; Antithyroid Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Creatinine; Glomerulonephritis | 2006 |
Simvastatin-induced bilateral leg compartment syndrome and myonecrosis associated with hypothyroidism.
Topics: Anticholesteremic Agents; Compartment Syndromes; Humans; Hypercholesterolemia; Hypothyroidism; Male; | 2007 |
Long-standing recurrent paroxysmal supraventricular tachycardia disappearing after cystic degeneration of an episodically hypersecreting toxic adenoma of the thyroid.
Topics: Adenoma; Adult; Female; Humans; Necrosis; Recurrence; Tachycardia, Paroxysmal; Thyroid Neoplasms; Th | 1984 |
Biological determinants of aldosterone-induced cardiac fibrosis in rats.
Topics: Aldosterone; Animals; Blotting, Northern; Collagen; Fibrosis; Heart; Histocytochemistry; Hypertensio | 1995 |
Appropriate intravenous doses of L-thyroxine and magnesium in a thyroidectomized patient with thyroid and parathyroid carcinomas receiving total parenteral nutrition during acute necrotizing pancreatitis.
Topics: Acute Disease; Carcinoma, Papillary; Female; Humans; Injections, Intravenous; Lung Neoplasms; Magnes | 1995 |
Thyroxine affects ventilation, lung morphometry, and necrosis of diaphragm in dystrophic hamsters.
Topics: Animals; Body Weight; Cricetinae; Diaphragm; Lung; Male; Mesocricetus; Muscular Dystrophy, Animal; N | 1995 |
Reduction of thyroxine-induced necrotic foci and thrombi in the mouse liver by androgen, oestrogen and glucocorticoid but not by progesterone.
Topics: Animals; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Gonadal Steroid Hormones; Incidence; | 1993 |
Is the increase in renal papillary phospholipid biosynthesis a protective mechanism against injury?
Topics: Animals; Kidney; Kidney Medulla; Male; Mercuric Chloride; Necrosis; Phosphatidylcholines; Phosphatid | 1996 |
Liver necrosis induced by thyroid hormone administration in rats fed ethanol.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Ethanol; Liver; Liver Diseases, Al | 2001 |
Suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. Effect on thyroid gland or on peripheral deiodination?
Topics: Animals; Antithyroid Agents; Chemical and Drug Induced Liver Injury; Ethanol; Hypoxia; Iodine; Male; | 1979 |
The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits.
Topics: Animals; Aortic Coarctation; Cardiomegaly; Collagen; Hydroxyproline; Isoenzymes; Isoproterenol; L-La | 1978 |
[Early histoenzymologic and ultrastructural changes induced by adrenalin-thyroxine and fat diet in rabbit aorta (author's transl)].
Topics: Alcohol Oxidoreductases; Animals; Aorta, Thoracic; Arteriosclerosis; Calcinosis; Cholesterol, Dietar | 1976 |
Thyroid function tests in acute viral hepatitis: relative reduction in serum thyroxine levels due to T4-TBG binding inhibitors in patients with severe liver cell necrosis.
Topics: Acute Disease; Hepatitis, Viral, Human; Humans; Liver; Necrosis; Thyroid Function Tests; Thyroxine; | 1989 |
Intrasplenic thyroid implantation with reverse splenocaval shunting: a morphologic and functional evaluation.
Topics: Animals; Autoradiography; Dogs; Iodine Isotopes; Necrosis; Radiography; Radionuclide Imaging; Spleen | 1971 |
Effect of hypophysectomy, adrenalectomy, and thyroidectomy on the beta--cells of the islets of Langerhans of the pancreas.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Atrophy; Blood Glucose; Diabetes Mellitus; Glycogen | 1969 |
[Photon and electron microscopy study of the rat myocardium after injection of L-thyroxine (influence of myocardial fixation technic)].
Topics: Animals; Body Weight; Cell Nucleus; Cytological Techniques; Heart; Heart Rate; Histological Techniqu | 1974 |
[Focal medionecrosis and its relationship with arteriosclerosis].
Topics: Adrenal Glands; Age Factors; Animals; Aortic Diseases; Arteriosclerosis; Blood Vessels; Calcinosis; | 1969 |
[Role of magnesium, potassium, antikaliuretic agents and hypocholesteremic agents in cardiac lesion development in rats fed a thrombogenic diet and Na 2 HPO 4 ].
Topics: Animals; Anticholesteremic Agents; Clofibrate; Diet, Atherogenic; Diuretics; Estrogens, Conjugated ( | 1972 |
Thyroid storm.
Topics: Adult; Age Factors; Body Temperature Regulation; Cardiovascular Diseases; Central Nervous System Dis | 1974 |
Pituitary apoplexy in acromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabe | 1968 |
The inhibition of the epinephrine--thyroxin induced arteriosclerosis by phentolamine.
Topics: Animals; Aorta; Arteriosclerosis; Cardiomyopathies; Epinephrine; Injections, Intravenous; Injections | 1970 |
Effect of thyroxine, reerpine and serotonin on allyl alcohol induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Alcohols; Animals; Body Temperature; Injections, Intraperitoneal; Liver; Male; | 1970 |
Experimental studies on thyroid-adrenal interrelationships in rats.
Topics: Adrenal Glands; Animals; Edema; Hemorrhage; Hyperemia; Necrosis; Propylthiouracil; Rats; Thyroxine | 1968 |