Page last updated: 2024-11-06

thyroxine and Nasopharyngeal Carcinoma

thyroxine has been researched along with Nasopharyngeal Carcinoma in 4 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.

Research Excerpts

ExcerptRelevanceReference
" Biochemical hypothyroidism was defined as an elevated level of serum thyroid-stimulating hormone (TSH) value with a normal or decreased level of serum free thyroxine (fT4) after radiotherapy."3.88Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients. ( Gao, X; He, B; Li, M; Lin, Z; Luo, R; Wang, D; Wu, VWC; Xu, Z; Yang, Z, 2018)
"Radiation-induced hypothyroidism is the most common thyroid disorder after radiotherapy in nasopharyngeal carcinoma (NPC) patients."1.48Pattern of radiation-induced thyroid gland changes in nasopharyngeal carcinoma patients in 48 months after radiotherapy. ( Gao, X; He, B; Lin, Z; Tam, SY; Wang, D; Wu, VWC; Yang, Z, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luo, R1
Wu, VWC2
He, B2
Gao, X2
Xu, Z1
Wang, D2
Yang, Z2
Li, M1
Lin, Z4
Tam, SY1
Chen, L2
Fang, Y1
Cai, A1
Zhang, T1
Wu, VW2
Lin, J1
Feng, H1

Other Studies

4 other studies available for thyroxine and Nasopharyngeal Carcinoma

ArticleYear
Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients.
    BMC cancer, 2018, May-18, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Models, Biological; Naso

2018
Pattern of radiation-induced thyroid gland changes in nasopharyngeal carcinoma patients in 48 months after radiotherapy.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hypothyroidism; Incidence; Male; Middle Aged; Nasoph

2018
Longitudinal study on the correlations of thyroid antibody and thyroid hormone levels after radiotherapy in patients with nasopharyngeal carcinoma with radiation-induced hypothyroidism.
    Head & neck, 2014, Volume: 36, Issue:2

    Topics: Adult; Aged; Autoantibodies; Biomarkers; Carcinoma; Female; Follow-Up Studies; Humans; Hypothyroidis

2014
A longitudinal study on the radiation-induced thyroid gland changes after external beam radiotherapy of nasopharyngeal carcinoma.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:1

    Topics: Adult; Aged; Carcinoma; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nasopharyngeal Carc

2011