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thyroxine and Myasthenia Gravis

thyroxine has been researched along with Myasthenia Gravis in 16 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
"In 52 patients with myasthenia gravis serum myoglobin showed a significant inverse correlation to circulating thyroxine and triiodothyronine levels."3.66Correlation between serum myoglobin and thyroid status in myasthenia gravis. ( Kiessling, WR, 1981)
"Ocular myasthenia gravis was managed with an anticholinesterase agent in combination with oral corticosteroids that provided additional control."1.25Ocular myasthenia gravis and Hashimoto's thyroiditis. ( Osher, RH; Smith, JL, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Machen, L1
MacIntosh, P1
GRUSIN, H1
BLOOMBERG, BM1
KLUGMAN, LH1
Kiessling, WR3
Pflughaupt, KW2
Ricker, K2
Haubitz, I2
Mertens, HG2
Nicolle, MW1
Weissel, M1
Mayr, N1
Zeitlhofer, J1
Pokrzywnicki, W1
Mazur, G1
Urbaniec, E1
Grzeszczak, W1
Rościszewska, D1
Kochańska, A1
Marinò, M1
Barbesino, G1
Pinchera, A1
Manetti, L1
Ricciardi, R1
Rossi, B1
Muratorio, A1
Braverman, LE1
Mariotti, S1
Chiovato, L1
Osher, RH1
Smith, JL1
Braithwaite, SS1
Brooks, MH1
Collins, S1
Bermes, EW1
Pather, R1
Rajput, MC1
Meiring, PD1
Takamori, M1
Gutmann, L1
Crosby, TW1
Martin, JD1
Gaelen, LH1
Levitan, S1
Norris, FH1
Panner, BJ1

Other Studies

16 other studies available for thyroxine and Myasthenia Gravis

ArticleYear
Considerations in Pediatric Proptosis.
    JAMA ophthalmology, 2018, 10-01, Volume: 136, Issue:10

    Topics: Adolescent; Antithyroid Agents; Blepharoptosis; Cholinesterase Inhibitors; Drug Therapy, Combination

2018
A CASE OF CHRONIC THYROTOXIC MYOPATHY.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Jun-20, Volume: 38

    Topics: Adenosine Triphosphate; Diagnosis, Differential; Humans; Hyperthyroidism; Metabolism; Muscular Disea

1964
Thyroid function and circulating antithyroid antibodies in myasthenia gravis.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Autoantibodies; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Thyro

1981
Correlation between serum myoglobin and thyroid status in myasthenia gravis.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:12

    Topics: Adolescent; Adult; Aged; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Myasthe

1981
[T3, T4, TSH and circulating antithyroglobulin antibodies in myasthenia gravis].
    Endokrinologie, 1981, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Aged; Antibodies; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle A

1981
Pseudo-myasthenia gravis and thymic hyperplasia in Graves' disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1999, Volume: 26, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antithyroid Agents; Diagnosis, Differential; F

1999
Clinical significance of autoimmune thyroid disease in myasthenia gravis.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2000, Volume: 108, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies; Autoantibodies; Autoimmune Diseases; Female;

2000
[Triiodothyroxine (T3), thyroxine (T4), thyreotropine (TSH) and myoglobin levels in patients with myasthenia gravis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1997, Volume: 2, Issue:9

    Topics: Adult; Female; Humans; Male; Myasthenia Gravis; Myoglobin; Retrospective Studies; Thyrotropin; Thyro

1997
Increased frequency of euthyroid ophthalmopathy in patients with Graves' disease associated with myasthenia gravis.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:9

    Topics: Adult; Antithyroid Agents; Female; Graves Disease; Humans; Iodine Radioisotopes; Male; Methimazole;

2000
Ocular myasthenia gravis and Hashimoto's thyroiditis.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Adult; Diplopia; Eye Diseases; Female; Goiter; Humans; Myasthenia Gravis; Prednisone; Pyridostigmine

1975
Plasmapheresis: an adjunct to medical management of severe hyperthyroidism.
    Journal of clinical apheresis, 1986, Volume: 3, Issue:2

    Topics: Adult; Combined Modality Therapy; Female; Humans; Hyperthyroidism; Myasthenia Gravis; Plasmapheresis

1986
Myasthenia gravis and pregnancy. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1988, Aug-06, Volume: 74, Issue:3

    Topics: Adult; Female; Humans; Myasthenia Gravis; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pyr

1988
Association between hypothyroidism and myasthenia gravis and a concept of generalized systemic auto-immunopathy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1967, Mar-25, Volume: 41, Issue:12

    Topics: Autoimmune Diseases; Beta-Globulins; Female; gamma-Globulins; Humans; Hypertension; Hypothyroidism;

1967
Myasthenic syndromes in hypothyroidism. Electrophysiological study of neuromuscular transmission and muscle contraction in two patients.
    Archives of neurology, 1972, Volume: 26, Issue:4

    Topics: Action Potentials; Adult; Anemia, Pernicious; Autoimmune Diseases; Electric Stimulation; Electromyog

1972
Myasthenia gravis and thyroid function.
    Archives of neurology, 1968, Volume: 18, Issue:1

    Topics: Adult; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Myasthenia Gravis; Thyroid

1968
Hypothyroid myopathy. Clinical, electromyographical, and ultrastructural observations.
    Archives of neurology, 1966, Volume: 14, Issue:6

    Topics: Biopsy; Curare; Electromyography; Histocytochemistry; Humans; Hypothyroidism; In Vitro Techniques; M

1966