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thyroxine and Muscle Relaxation

thyroxine has been researched along with Muscle Relaxation in 9 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"Hyperthyroidism was induced by subcutaneous injections of L-thyroxine (T(4)) (500 mg/kg/day) for 3 days in order to study whether adrenergic and muscarinic receptor-mediated vascular responses alter at an early stage of the disease."3.70Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae. ( Honda, H; Iwata, T; Kogo, H; Mochizuki, T, 2000)
"In our experiments hyperthyroidism has a sensitizing influence on vascular responses induced by the beta-adrenoceptor agonist isoproterenol and the selective beta 2-adrenoceptor agonist salbutamol."1.29The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries. ( Pfaffendorf, M; van Zwieten, PA; Winkler Prins, EA; Zwaveling, J, 1996)
"Slow muscle relaxation was observed on examination in 11 patients and 12 out of 16 patients had a reduced quadriceps maximum relaxation rate (MRR) and 11 out of 15 had a prolonged ankle jerk relaxation time (AJRT)."1.27Effect of treatment on skeletal muscle dysfunction in hypothyroidism. ( Edwards, RH; Khaleeli, AA, 1984)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laukkarinen, J1
Sand, J1
Aittomäki, S1
Pörsti, I1
Kööbi, P1
Kalliovalkama, J1
Silvennoinen, O1
Nordback, I1
Taylor, SE1
Khaleeli, AA1
Edwards, RH1
Zwaveling, J2
Winkler Prins, EA1
Pfaffendorf, M2
van Zwieten, PA2
Chang, KC1
Figueredo, VM1
Schreur, JH1
Kariya, K1
Weiner, MW1
Simpson, PC1
Camacho, SA1
Honda, H1
Iwata, T1
Mochizuki, T1
Kogo, H1
Ozdemirci, S1
Yildiz, F1
Utkan, T1
Ulak, G1
Cetinaslan, B1
Erden, F1
Gacar, N1
O'Donnell, SR1
Wanstall, JC1

Other Studies

9 other studies available for thyroxine and Muscle Relaxation

ArticleYear
Mechanism of the prorelaxing effect of thyroxine on the sphincter of Oddi.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:6

    Topics: Acetylcholine; Analysis of Variance; Animals; Blotting, Western; Culture Techniques; Dose-Response R

2002
Additional evidence against universal modulation of beta-adrenoceptor responses by excessive thyroxine.
    British journal of pharmacology, 1983, Volume: 78, Issue:4

    Topics: Animals; Butoxamine; Guinea Pigs; Kinetics; Male; Muscle Relaxation; Muscle, Smooth; Receptors, Adre

1983
Effect of treatment on skeletal muscle dysfunction in hypothyroidism.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Ankle; Creatine Kinase; Creatinine; Female; Humans; Hypothyroidism; Male; M

1984
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adren

1996
The direct effects of thyroid hormones on rat mesenteric resistance arteries.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:1

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Muscle Contraction; M

1997
Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts.
    The Journal of clinical investigation, 1997, Oct-01, Volume: 100, Issue:7

    Topics: Animals; Aorta; Aortic Valve Stenosis; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPas

1997
Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae.
    General pharmacology, 2000, Volume: 34, Issue:6

    Topics: Acetylcholine; Acute Disease; Animals; Aorta; Blood Pressure; Blotting, Western; Body Weight; Cardio

2000
Impaired neurogenic and endothelium-dependent relaxant responses of corpus cavernosum smooth muscle from hyperthyroid rabbits.
    European journal of pharmacology, 2001, Sep-28, Volume: 428, Issue:1

    Topics: Acetylcholine; Animals; Electric Stimulation; Endothelium, Vascular; Hyperthyroidism; In Vitro Techn

2001
Thyroxine treatment of aged or young rats demonstrates that vascular responses mediated by beta-adrenoceptor subtypes can be differentially regulated.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; In Vitro Tec

1986