thyroxine has been researched along with Muscle Disorders in 55 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A female patient with Hashimoto's autoimmune thyroiditis and myopathic symptoms is reported." | 5.28 | Autoimmune thyroiditis and myopathy. Reversibility of myopathic alterations under thyroxine therapy. ( Frank, B; Klingelhöfer, J; Schönle, PW, 1989) |
| "Subclinical hypothyroidism, which is defined as elevated thyroid-stimulating hormone (TSH) levels with free thyroxine concentrations within the reference range, is a common disorder that increases with age and affects up to 18% of the elderly, with a higher prevalence in women compared to men." | 4.90 | Subclinical hypothyroidism: summary of evidence in 2014. ( Baumgartner, C; Blum, MR; Rodondi, N, 2014) |
| "Myxoedema coma is a rare emergency needing prompt recognition and urgent treatment before diagnostic confirmation." | 2.36 | Myxoedema coma. A review. ( Khaleeli, A, 1978) |
| "A 41-year-old Caucasian man under treatment for hypothyroidism presented with acute-onset severe pain in his forearm for no obvious reason and was admitted to our emergency room." | 1.56 | Hoffmann's syndrome necessitating forearm fasciotomy: a case report. ( Aarsæther, E; Due, J; Halvorsen, H; Joakimsen, R; Sildnes, T; Sivertsen, O, 2020) |
| "Atrophic autoimmune thyroiditis (ATT) related acquired hypothyroidism causes interruption of growth, obesity, and bone age retardation in early ages while goitrogenic thyroiditis has a higher incidence rate and mostly presents with diffuse goiter." | 1.43 | A case with atrophic autoimmune thyroiditis-related hypothyroidism causing multisystem involvement in early childhood. ( Aycan, Z; Çetinkaya, S; Doğan, V; Keskin, M; Kurnaz, E; Savaş-Erdeve, Ş, 2016) |
| "We describe a patient with primary hypothyroidism, presenting solely with a clinical picture of myositis with very high levels of creatine phosphokinase (CPK), which normalised after 12 weeks of treatment with levothyroxine." | 1.36 | Myopathy presenting as a sole manifestation of hypothyroidism. ( Jain, R; Kant, S; Kumar, V; Madhu, SV; Prakash, V, 2010) |
| "We report four patients with primary hypothyroidism (3 female, aged 47, 46, 49 and 34 years old) whose principal manifestation was muscle involvement." | 1.29 | [Hypothyroid myopathy. Communication of 4 cases]. ( Arriagada, P; Avaria, MA; González, G; Jalil, P; Michaud, P; Téllez, R; Vergara, F, 1994) |
| "A female patient with Hashimoto's autoimmune thyroiditis and myopathic symptoms is reported." | 1.28 | Autoimmune thyroiditis and myopathy. Reversibility of myopathic alterations under thyroxine therapy. ( Frank, B; Klingelhöfer, J; Schönle, PW, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (43.64) | 18.7374 |
| 1990's | 5 (9.09) | 18.2507 |
| 2000's | 12 (21.82) | 29.6817 |
| 2010's | 10 (18.18) | 24.3611 |
| 2020's | 4 (7.27) | 2.80 |
| Authors | Studies |
|---|---|
| Asirvatham, AR | 1 |
| Balachandran, K | 1 |
| Balasubramanian, S | 1 |
| Mahadevan, S | 1 |
| Ni, J | 1 |
| Zhang, L | 1 |
| Zhang, X | 1 |
| Aarsæther, E | 1 |
| Joakimsen, R | 1 |
| Halvorsen, H | 1 |
| Sildnes, T | 1 |
| Sivertsen, O | 1 |
| Due, J | 1 |
| Schauer, C | 1 |
| Koo, YE | 1 |
| McBride, S | 1 |
| Patel, A | 1 |
| Lin, N | 1 |
| Wang, J | 1 |
| Liao, W | 1 |
| Wen, Y | 1 |
| Baumgartner, C | 1 |
| Blum, MR | 1 |
| Rodondi, N | 1 |
| Oden Akman, A | 1 |
| Tayfun, M | 1 |
| Demirel, F | 1 |
| Ucakturk, SA | 1 |
| Gungor, A | 1 |
| Cimbek, EA | 1 |
| Şen, Y | 1 |
| Yuca, SA | 1 |
| Çam, D | 1 |
| Gür, C | 1 |
| Peru, H | 1 |
| Kurnaz, E | 1 |
| Savaş-Erdeve, Ş | 1 |
| Keskin, M | 1 |
| Doğan, V | 1 |
| Çetinkaya, S | 1 |
| Aycan, Z | 1 |
| Tuncel, D | 1 |
| Cetinkaya, A | 1 |
| Kaya, B | 1 |
| Gokce, M | 1 |
| Lando, HM | 1 |
| Burman, KD | 1 |
| Rodríguez-Garrocho, A | 1 |
| Jover-Sáenz, A | 1 |
| Barcenilla-Gaite, F | 1 |
| Porcel-Pérez, JM | 1 |
| Madhu, SV | 1 |
| Jain, R | 1 |
| Kant, S | 1 |
| Prakash, V | 1 |
| Kumar, V | 1 |
| Lee, YS | 1 |
| Moon, SS | 1 |
| Serranti, D | 1 |
| Indolfi, G | 1 |
| Bartolini, E | 1 |
| Galli, L | 1 |
| de Martino, M | 1 |
| Resti, M | 1 |
| Verma, R | 1 |
| Lalla, R | 1 |
| Sahu, R | 1 |
| Glueck, CJ | 1 |
| Streicher, P | 1 |
| SCHWARTZ, NB | 1 |
| LEIN, A | 1 |
| RYAN, HF | 1 |
| YANCEY, AG | 1 |
| AOKI, I | 1 |
| GRUSIN, H | 1 |
| BLOOMBERG, BM | 1 |
| KLUGMAN, LH | 1 |
| Tullu, MS | 1 |
| Udgirkar, VS | 1 |
| Muranjan, MN | 1 |
| Sathe, SA | 1 |
| Kamat, JR | 1 |
| Freeston, J | 1 |
| Gough, A | 1 |
| Schalin-Jäntti, C | 1 |
| Sane, T | 1 |
| Välimäki, M | 1 |
| Salaria, M | 1 |
| Parmar, VR | 1 |
| Miyake, I | 2 |
| Kaku, H | 1 |
| Hiromatsu, Y | 2 |
| Kolyvanos Naumann, U | 1 |
| Furer, J | 1 |
| Käser, L | 1 |
| Vetter, W | 1 |
| Dalir-Naghadeh, B | 1 |
| Rezaei, SA | 1 |
| Tajima, K | 1 |
| Mashita, K | 1 |
| Yamane, T | 1 |
| Yoshikawa, H | 1 |
| Kawamura, S | 1 |
| Kang, J | 1 |
| Kajiyama, Y | 1 |
| Moriwaki, K | 1 |
| Tarui, S | 1 |
| Novakofski, JE | 1 |
| Kauffman, RG | 1 |
| McKeran, RO | 3 |
| Slavin, G | 3 |
| Ward, P | 3 |
| Paul, E | 1 |
| Mair, WG | 2 |
| Oscuro, F | 1 |
| Antico, CN | 1 |
| Calvanese, A | 1 |
| Chianese, U | 1 |
| Gallo, M | 1 |
| Téllez, R | 1 |
| Arriagada, P | 1 |
| Avaria, MA | 1 |
| Jalil, P | 1 |
| González, G | 1 |
| Vergara, F | 1 |
| Michaud, P | 1 |
| Rodolico, C | 1 |
| Toscano, A | 1 |
| Benvenga, S | 1 |
| Mazzeo, A | 1 |
| Bartolone, S | 1 |
| Bartolone, L | 1 |
| Girlanda, P | 1 |
| Monici, MC | 1 |
| Migliorato, A | 1 |
| Trimarchi, F | 1 |
| Vita, G | 1 |
| Finsterer, J | 1 |
| Stöllberger, C | 1 |
| Grossegger, C | 1 |
| Kroiss, A | 1 |
| Wadhwa, S | 1 |
| Khaleeli, A | 1 |
| Paul, EA | 1 |
| Andrews, TM | 1 |
| Virmani, A | 1 |
| Gambhir, A | 1 |
| Iyer, PU | 1 |
| Frank, B | 1 |
| Schönle, PW | 1 |
| Klingelhöfer, J | 1 |
| Bowman, CA | 1 |
| Jeffcoate, WJ | 1 |
| Pattrick, M | 1 |
| Doherty, M | 1 |
| Kojima, S | 1 |
| Matsui, T | 1 |
| Uchigata, M | 1 |
| Tanabe, H | 1 |
| Shishiba, Y | 1 |
| Gutmann, L | 1 |
| Crosby, TW | 1 |
| Takamori, M | 1 |
| Martin, JD | 1 |
| Hurwitz, LJ | 1 |
| McCormick, D | 1 |
| Allen, IV | 1 |
| Dobson, HL | 1 |
| Kasahara, M | 1 |
| Mawatari, S | 1 |
| Takagi, A | 1 |
| Rowland, LP | 1 |
| Hedley, AJ | 1 |
| Coffman, JR | 1 |
| Afifi, AK | 1 |
| Najjar, SS | 1 |
| Mire-Salman, J | 1 |
| Bergman, RA | 1 |
| Hamburger, JI | 1 |
| Sugar, HS | 1 |
| Cross, HE | 1 |
| Hollander, CS | 1 |
| Rimoin, DL | 1 |
| McKusick, VA | 1 |
| Norris, FH | 2 |
| Panner, BJ | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone Replacement for Subclinical Hypothyroidism and Dyslipidemia in Patients With Atherosclerotic Cardiovascular Diseases (ThyroHeart-Lipid Study)[NCT03606824] | 248 participants (Anticipated) | Interventional | 2019-03-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for thyroxine and Muscle Disorders
| Article | Year |
|---|---|
Hypothyroid myopathy with periodic paralysis as the main symptom: a case report and literature review.
Topics: Adult; Congenital Hypothyroidism; Humans; Male; Muscle, Skeletal; Muscular Diseases; Paralysis; Thyr | 2020 |
Subclinical hypothyroidism: summary of evidence in 2014.
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Mental Disorde | 2014 |
Cardiovascular and medical ramifications of treatment of subclinical hypothyroidism.
Topics: Adult; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Muscular Diseases; Pregnancy; | 2003 |
Reversible myopathy and renal impairment.
Topics: Adult; Biomarkers; Creatine Kinase; Humans; Hypothyroidism; Kidney Diseases; Male; Muscular Diseases | 2004 |
[Thyroid myopathy (hypothyroid myopathy)].
Topics: Humans; Hypothyroidism; Muscular Diseases; Thyroxine | 2006 |
[Hypothyroid myopathy].
Topics: Diagnosis, Differential; Humans; Hypothyroidism; Muscular Diseases; Prognosis; Thyroxine | 2001 |
Myxoedema coma. A review.
Topics: Acute Kidney Injury; Coma; Diagnosis, Differential; Hemorrhage; Humans; Hypoglycemia; Hyponatremia; | 1978 |
Myxoedema.
Topics: Anemia; Blood Coagulation Disorders; Central Nervous System Diseases; Electrocardiography; Female; G | 1972 |
47 other studies available for thyroxine and Muscle Disorders
| Article | Year |
|---|---|
Myoedema in secondary hypothyroidism: an often unelicited clinical sign of hypothyroid myopathy.
Topics: Adenoma; Adult; Humans; Hydrocortisone; Hypopituitarism; Hypothyroidism; Male; Muscular Diseases; Pi | 2019 |
Marked elevation of creatine phosphokinase alone caused by sintilimab - beware of hypothyroid myopathy.
Topics: Adenocarcinoma of Lung; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2020 |
Hoffmann's syndrome necessitating forearm fasciotomy: a case report.
Topics: Adult; Compartment Syndromes; Fasciotomy; Forearm; Humans; Hypothyroidism; Male; Muscular Diseases; | 2020 |
Hypothyroidism causing bilateral lower-limb compartment syndrome.
Topics: Adolescent; Anterior Compartment Syndrome; Conservative Treatment; Creatine Kinase; Exercise; Hemogl | 2020 |
Association of Van Wyk Grumbach and Debre Semelaigne Syndromes with Severe Hypothyroidism.
Topics: Adolescent; Congenital Hypothyroidism; Diagnosis, Differential; Female; Humans; Hypertrophy; Muscle, | 2015 |
Kocher-Debré-Semelaigne syndrome with rhabdomyolysis and increased creatinine.
Topics: Adolescent; Congenital Hypothyroidism; Creatine Kinase; Creatinine; Hashimoto Disease; Humans; Hyper | 2015 |
A case with atrophic autoimmune thyroiditis-related hypothyroidism causing multisystem involvement in early childhood.
Topics: Child, Preschool; Congenital Hypothyroidism; Echocardiography; Female; Hashimoto Disease; Humans; Hy | 2016 |
Hoffmann's syndrome: a case report.
Topics: Adult; Humans; Hypertrophy; Hypothyroidism; Male; Muscular Diseases; Thyroiditis, Autoimmune; Thyrox | 2008 |
Two cases of statin-induced myopathy caused by induced hypothyroidism.
Topics: Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoth | 2008 |
[Hoffmann's syndrome as an onset for us of hypothyroid myopathy].
Topics: Adult; Autoimmune Diseases; Humans; Hypertrophy; Hypothyroidism; Male; Muscle Weakness; Muscle, Skel | 2010 |
Myopathy presenting as a sole manifestation of hypothyroidism.
Topics: Adult; Creatine Kinase; Hormone Replacement Therapy; Humans; Hypothyroidism; Male; Muscle Weakness; | 2010 |
A case of Sheehan's syndrome that manifested as bilateral ptosis.
Topics: Blepharoptosis; Electromyography; Female; Glucocorticoids; Humans; Hypopituitarism; Hypothyroidism; | 2011 |
Raised serum aminotransferase levels and muscle pseudohypertrophy caused by hypothyroidism.
Topics: Adolescent; Biomarkers; Creatine Kinase; Diagnosis, Differential; Hormone Replacement Therapy; Human | 2013 |
Hypothyroid myopathy mimicking postpolio syndrome.
Topics: Adult; Calcium; Diagnosis, Differential; Dietary Supplements; Female; Hashimoto Disease; Humans; Hyp | 2012 |
Effects of thyroxin on skeletal muscle function.
Topics: Disease; Hyperthyroidism; Hypothyroidism; Muscle, Skeletal; Muscles; Muscular Diseases; Thyroid Dise | 1955 |
THYROTOXIC MYOPATHY: ONE CASE PRECIPITATED BY PREGNANCY.
Topics: Antacids; Antithyroid Agents; Female; Humans; Hyperthyroidism; Iodine Isotopes; Muscle Relaxants, Ce | 1963 |
[CLINICAL AND PATHOLOGIC STUDIES IN THYROTOXIC MYOPATHY].
Topics: Adolescent; Basal Metabolism; Child; Chlorides; Creatine; Creatinine; Endocrine System Diseases; Hum | 1963 |
A CASE OF CHRONIC THYROTOXIC MYOPATHY.
Topics: Adenosine Triphosphate; Diagnosis, Differential; Humans; Hyperthyroidism; Metabolism; Muscular Disea | 1964 |
Kocher-Debre-Semelaigne syndrome: hypothyroidism with muscle pseudohypertrophy.
Topics: Age Determination by Skeleton; Child; Female; Humans; Hypertrophy; Hypothyroidism; Infant; Male; Mus | 2003 |
[Myopathy and increased liver enzyme levels in a young athlete].
Topics: Adult; Diagnosis, Differential; Follow-Up Studies; Humans; Hypothyroidism; Liver Function Tests; Mal | 2004 |
Kocher Debre Semelaigne syndrome--a case report and review of literature.
Topics: Child; Humans; Hypertrophy; Hypothyroidism; Male; Muscle, Skeletal; Muscular Diseases; Syndrome; Thy | 2004 |
[Hypothyroidism. Main symptoms: fatigue, weight gain, depression, myalgia, edema].
Topics: Adult; Depression; Diagnosis, Differential; Edema; Fatigue; Female; Humans; Hypothyroidism; Muscular | 2007 |
Assessment of serum thyroid hormone concentrations in lambs with selenium deficiency myopathy.
Topics: Animals; Creatine Kinase; Female; Glutathione Peroxidase; Male; Muscular Diseases; Selenium; Sheep; | 2008 |
Thyrotoxic myopathy associated with subacute thyroiditis.
Topics: Adult; Humans; Male; Muscular Atrophy; Muscular Diseases; Thyroiditis; Thyroxine; Triiodothyronine | 1984 |
Biological detection of heterozygosity for double muscling in cattle. II. Thyroid hormone concentrations.
Topics: Animals; Cattle; Cattle Diseases; Genetic Carrier Screening; Hypertrophy; Muscular Diseases; Thyroxi | 1981 |
Hypothyroid myopathy. A clinical and pathologaical study.
Topics: Adult; Cell Nucleus; Female; Humans; Hypothyroidism; Male; Microscopy, Electron; Middle Aged; Mitoch | 1980 |
[Thyroid myopathy in an aged woman].
Topics: Aged; Diagnosis, Differential; Female; Humans; Hypothyroidism; Muscular Diseases; Syndrome; Thyroxin | 1994 |
[Hypothyroid myopathy. Communication of 4 cases].
Topics: Adult; Electromyography; Female; Humans; Hypothyroidism; Male; Middle Aged; Muscular Diseases; Progn | 1994 |
Myopathy as the persistently isolated symptomatology of primary autoimmune hypothyroidism.
Topics: Adolescent; Adult; Autoimmune Diseases; Female; Humans; Hypothyroidism; Male; Microscopy, Electron; | 1998 |
Hypothyroid myopathy with unusually high serum creatine kinase values.
Topics: Creatine Kinase; Electrocardiography; Electromyography; Humans; Hypothyroidism; Male; Middle Aged; M | 1999 |
Myopathy as the sole manifestation of thyroprivic hypothyroidism of autoimmune etiology.
Topics: Adult; Autoimmune Diseases; Biopsy; Electromyography; Follow-Up Studies; Humans; Hypothyroidism; Mal | 2001 |
Central nuclear counts in muscle fibres before and during treatment in hypothyroid myopathy.
Topics: Adult; Cell Nucleus; Creatine Kinase; Female; Humans; Hypothyroidism; Male; Middle Aged; Muscles; Mu | 1979 |
Muscle fibre type changes in hypothyroid myopathy.
Topics: Adult; Aged; Biopsy, Needle; Female; Humans; Hypothyroidism; Male; Middle Aged; Muscles; Muscular Di | 1975 |
Kocher Debre Semelaigne syndrome mimicking primary muscle disease.
Topics: Child, Preschool; Diagnosis, Differential; Humans; Hypothyroidism; Male; Muscular Diseases; Syndrome | 1990 |
Autoimmune thyroiditis and myopathy. Reversibility of myopathic alterations under thyroxine therapy.
Topics: Aged; Female; Humans; Muscular Diseases; Thyroiditis, Autoimmune; Thyroxine | 1989 |
Bilateral adhesive capsulitis, oligoarthritis and proximal myopathy as presentation of hypothyroidism.
Topics: Arthritis; Blood Sedimentation; C-Reactive Protein; Diagnosis, Differential; Humans; Hypothyroidism; | 1988 |
[Hypothyroid myopathy, report of a case developing after commencement of substitution therapy].
Topics: Female; Humans; Hypothyroidism; Middle Aged; Muscular Diseases; Thyroid (USP); Thyroxine | 1985 |
The Eaton-Lambert syndrome and autoimmune disorders.
Topics: Adult; Anemia, Pernicious; Autoimmune Diseases; Bronchial Neoplasms; Carcinoma; Electrodiagnosis; Hu | 1972 |
Reduced muscle alpha-glucosidase (acid-maltase) activity in hypothyroid myopathy.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Creatine Kinase; Fructose-Bisphosphate Ald | 1970 |
NADH-2 cytochrome C reductase and cytochrome C oxidase in experimental muscle disorders.
Topics: Animals; Denervation; Electron Transport Complex IV; Electrophoresis; In Vitro Techniques; Muscle Pr | 1964 |
Adenyl cyclase in normal and pathologic human muscle.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclases; Amyotrophic Lateral Sclerosis; | 1974 |
Bone and muscle defects in foals.
Topics: Animals; Bone Diseases, Developmental; Diet Therapy; Horse Diseases; Horses; Muscular Diseases; Orth | 1973 |
The myopathology of the Kocher-Debré-Sémélaigne syndrome. Electromyography, light- and electron-microscopic study.
Topics: Action Potentials; Child; Child, Preschool; Congenital Hypothyroidism; Creatine Kinase; Electromyogr | 1974 |
What the internist should know about the ophthalmopathy of Graves' disease.
Topics: Adult; Diplopia; Eye; Eye Diseases; Eye Injuries; Eye Manifestations; Eyelid Diseases; Female; Glauc | 1972 |
Familial agoitrous cretinism accompanied by musclar hypertrophy.
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Congenital Hypothyroidism; Fe | 1968 |
Hypothyroid myopathy.
Topics: Electromyography; Muscular Diseases; Myxedema; Thyroxine | 1965 |
Hypothyroid myopathy. Clinical, electromyographical, and ultrastructural observations.
Topics: Biopsy; Curare; Electromyography; Histocytochemistry; Humans; Hypothyroidism; In Vitro Techniques; M | 1966 |