thyroxine has been researched along with Multiple Myeloma in 12 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the prevalence of euthyroid hypertriiodothyroninemia and/or hyperthyroxinemia and its clinical characteristics in multiple myeloma (MM) patients." | 8.02 | The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics. ( Chen, Z; Hu, Y; Liu, A; Pan, Q; Wang, G; Zhang, W; Zhang, Y, 2021) |
| "To evaluate the prevalence of euthyroid hypertriiodothyroninemia and/or hyperthyroxinemia and its clinical characteristics in multiple myeloma (MM) patients." | 4.02 | The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics. ( Chen, Z; Hu, Y; Liu, A; Pan, Q; Wang, G; Zhang, W; Zhang, Y, 2021) |
| "Osteoporosis is a skeletal disorder characterized by decreased mass and compromised bone strength predisposing to an increased risk of fractures." | 2.52 | Management of endocrine disease: Secondary osteoporosis: pathophysiology and management. ( Canalis, E; Mirza, F, 2015) |
| "This integrin is overexpressed in multiple myeloma (MM) and other cancers." | 1.40 | Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells. ( Ashur-Fabian, O; Baharal, T; Cohen, K; Davis, PJ; Ellis, M; Erez, D; Flint, N; Hercbergs, A; Shalev, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, Q | 1 |
| Zhang, Y | 1 |
| Zhang, W | 1 |
| Hu, Y | 1 |
| Chen, Z | 1 |
| Liu, A | 1 |
| Wang, G | 1 |
| Cohen, K | 3 |
| Ellis, M | 3 |
| Shinderman, E | 1 |
| Khoury, S | 2 |
| Davis, PJ | 3 |
| Hercbergs, A | 3 |
| Ashur-Fabian, O | 3 |
| Flint, N | 1 |
| Shalev, S | 1 |
| Erez, D | 1 |
| Baharal, T | 1 |
| Mirza, F | 1 |
| Canalis, E | 1 |
| Pekić, B | 2 |
| Popović, M | 1 |
| Pavelić, K | 2 |
| Gabrilovac, J | 1 |
| Bratic-Mikes, V | 1 |
| Boranic, M | 1 |
| Alexander, NM | 1 |
| Gattra, R | 1 |
| Nishimoto, M | 1 |
| Cissewski, K | 1 |
| Faix, JD | 1 |
| Reinwein, D | 1 |
| Moses, AC | 1 |
| van Zaanen, HC | 1 |
| Romijn, JA | 1 |
| Sauerwein, HP | 1 |
| Lokhorst, HM | 1 |
| Warnaar, SO | 1 |
| Aarden, LA | 1 |
| Endert, E | 1 |
| van Oers, MH | 1 |
| Raab, W | 1 |
| Keane, PM | 1 |
| Pegg, PJ | 1 |
| Johnson, E | 1 |
1 review available for thyroxine and Multiple Myeloma
| Article | Year |
|---|---|
Management of endocrine disease: Secondary osteoporosis: pathophysiology and management.
Topics: Acromegaly; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Autoimmune Diseases; Celiac Disea | 2015 |
11 other studies available for thyroxine and Multiple Myeloma
| Article | Year |
|---|---|
The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics.
Topics: Humans; Multiple Myeloma; Prevalence; Thyrotropin; Thyroxine; Triiodothyronine | 2021 |
Relevance of the thyroid hormones-αvβ3 pathway in primary myeloma bone marrow cells and to bortezomib action.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Bone Marrow Cell | 2015 |
Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells.
Topics: Bortezomib; Cell Adhesion; Cell Movement; Cell Proliferation; Humans; Matrix Metalloproteinase 9; Mu | 2014 |
Thyroid hormone is a MAPK-dependent growth factor for human myeloma cells acting via αvβ3 integrin.
Topics: Cell Growth Processes; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Mitogen-Activated Protein Kin | 2011 |
[Changes in hormone concentrations in the blood of patients with malignant diseases of the blood].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Growth Hormone; Hodgkin Disease; Hormones; Humans; Hydroco | 1984 |
Hormonal changes in patients with haematological malignancies.
Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho | 1981 |
Myeloma immunoglobulin interferes with serum thyroxine analysis by homogeneous enzyme immunoassay.
Topics: Binding, Competitive; Blood Proteins; Female; Humans; Immunoenzyme Techniques; Immunoglobulins; Male | 1980 |
Factitious hyperthyroxinemia due to a monoclonal IgA in a case of multiple myeloma.
Topics: Antibodies, Monoclonal; False Positive Reactions; Female; Humans; Immunoelectrophoresis; Immunoglobu | 1993 |
Modulation of chronic excessive interleukin-6 production in multiple myeloma does not affect thyroid hormone concentrations.
Topics: Aged; Animals; Antibodies, Monoclonal; Biological Assay; Female; Humans; Immunoglobulin G; Infusions | 1997 |
[The clinical significance of urinary hydroxyproline determinations (author's transl)].
Topics: Alkaline Phosphatase; Animals; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Burns; Carbon R | 1972 |
Estimation of thyroxine binding protein capacities using a non-electrophoretic technique.
Topics: Barbiturates; Blood Protein Electrophoresis; Buffers; Cholestasis; Female; Humans; Multiple Myeloma; | 1969 |