Compounds > thyroxine
Page last updated: 2024-11-06

thyroxine and Metabolic Syndrome

thyroxine has been researched along with Metabolic Syndrome in 53 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"The study focuses on the levels of prolactin, cortisol, free thyroxine (fT4) and thyroid-stimulating hormone (TSH) as markers of Metabolic Syndrome (MS) which is a risk factor for Coronary Artery Disease (CAD) and type 2 Diabetes Mellitus (DM)."7.91PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS. ( Chmyr, N; Dutka, R; Leontieva, Z; Svitlyk, H, 2019)
"To investigate the relationship among serum reproductive hormone levels, serum homocysteine (Hcy) levels, metabolic syndrome (MS), and the components of MS in middle-aged and elderly males."7.83[Serum homocysteine and metabolic syndrome in middle-aged and elderly men]. ( Gu, YQ; Ji, YD; Lu, WH; Wang, CG; Yang, YH; Yuan, D; Zhang, BL; Zhao, MJ; Zhou, SJ, 2016)
" Secondary outcomes were the measurement of thyroid hormones (free T4 and TSH), leptin levels, and insulin resistance index (HOMA2-IR)."7.81Prevalence of the metabolic syndrome, insulin resistance index, leptin and thyroid hormone levels in the general population of Merida (Venezuela). ( Baptista, T; Gómez Pérez, R; Marquina, D; Uzcátegui, E; Uzcátegui, L; Valery, L, 2015)
" This study assessed the relationship between free thyroxine and clinical features of metabolic syndrome (MS)."7.73Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population. ( Lai, WA; Lin, SY; Liu, PH; Sheu, WH; Wang, YY, 2005)
"Euthyroid subjects with suspected NAFLD are characterized by higher FT3, lower FT4 and higher FT3/FT4 ratio, probably consequent to central obesity."5.46Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study. ( Amini, M; Blokzijl, H; Dullaart, RP; Faber, KN; Schreuder, TC; van den Berg, EH; van Tienhoven-Wind, LJ, 2017)
"Conventional risk factors for NAFLD were assessed as well as serum levels of TSH, FT3 and FT4."5.42Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects. ( Guan, L; Guan, Q; Jiang, Q; Jiang, Z; Lin, H; Liu, G; Yu, C; Zhang, N; Zhang, X; Zhang, Y; Zheng, X, 2015)
"Metabolic syndrome was determined by definition of the Joint Interim Statement adjusted for the Iranian population."5.40Serum free thyroxine concentration is associated with metabolic syndrome in euthyroid subjects. ( Amouzegar, A; Azizi, F; Mehran, L; Moayedi, M; Tohidi, M, 2014)
"Controversy remains as to the risk of cardiovascular disease (CVD) associated with subclinical hypothyroidism (SCH), defined as an increased serum thyrotropin (TSH) concentration with normal free thyroxine and triiodothyronine levels."4.84Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence? ( Duntas, LH; Wartofsky, L, 2007)
" People were placed into subclinical hypothyroidism and euthyroidism groups according to serum-free thyroxine and TSH concentrations."4.12Sex-specific Association of Subclinical Hypothyroidism With Incident Metabolic Syndrome: A Population-based Cohort Study. ( Chen, S; Gao, B; Guo, X; Jiang, Y; Kang, X; Li, X; Liu, Y; Tao, L; Wang, W; Wu, Z; Zhang, H; Zhang, J; Zhao, Y; Zhou, D, 2022)
"The study focuses on the levels of prolactin, cortisol, free thyroxine (fT4) and thyroid-stimulating hormone (TSH) as markers of Metabolic Syndrome (MS) which is a risk factor for Coronary Artery Disease (CAD) and type 2 Diabetes Mellitus (DM)."3.91PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS. ( Chmyr, N; Dutka, R; Leontieva, Z; Svitlyk, H, 2019)
"BMI = body mass index FT4 = free thyroxine MetS = metabolic syndrome OR = odds ratio T3 = triiodothyronine TSH = thyroid-stimulating hormone WC = waist circumference."3.83THE ASSOCIATION OF THYROID HORMONES AND TSH WITH THE METABOLIC SYNDROME IN EUTHYROID TAIWANESE INDIVIDUALS. ( Huang, CY; Hwang, LC, 2016)
"To investigate the relationship among serum reproductive hormone levels, serum homocysteine (Hcy) levels, metabolic syndrome (MS), and the components of MS in middle-aged and elderly males."3.83[Serum homocysteine and metabolic syndrome in middle-aged and elderly men]. ( Gu, YQ; Ji, YD; Lu, WH; Wang, CG; Yang, YH; Yuan, D; Zhang, BL; Zhao, MJ; Zhou, SJ, 2016)
" Secondary outcomes were the measurement of thyroid hormones (free T4 and TSH), leptin levels, and insulin resistance index (HOMA2-IR)."3.81Prevalence of the metabolic syndrome, insulin resistance index, leptin and thyroid hormone levels in the general population of Merida (Venezuela). ( Baptista, T; Gómez Pérez, R; Marquina, D; Uzcátegui, E; Uzcátegui, L; Valery, L, 2015)
" In all subjects, thyroid stimulating hormone (TSH), free thyroxine (FT4), fasting plasma levels of insulin and glucose, homeostasis model assessment for insulin resistance, and obesity parameters were assessed."3.79Relationship of thyroid function with obesity and type 2 diabetes in euthyroid Tunisian subjects. ( Abid, H; Ammar, M; Bchir, F; Berhouma, R; Clerget-Froidevaux, MS; Demeneix, B; Elgaaied, AB; Guissouma, H; Jarboui, S; Kouidhi, S; Rouissi, K; Seugnet, I, 2013)
" Thyroid function was stratified as euthyroid or subclinical hypothyroidism (SCH) status and subsequently by free thyroxine (FT(4)) and TSH tertiles."3.76TSH and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects. ( Aguilar-Salinas, CA; Alvirde-Garcia, U; Arellano-Campos, O; Choza, R; Garay-Sevilla, ME; Garduño-Garcia, Jde J; Gomez-Perez, FJ; López-Carrasco, G; Malacara, JM; Mehta, R; Padilla Mendoza, ME; Sauque, L, 2010)
" Fasting TSH, free thyroxine (FT4), insulin, glucose, and the level of insulin resistance, estimated by the homeostasis model assessment for insulin resistance (HOMA-IR) were measured."3.75Thyroid stimulating hormone is associated with metabolic syndrome in euthyroid postmenopausal women. ( Ahn, KH; Cho, GJ; Hong, SC; Hur, JY; Kim, SH; Kim, T; Kim, YT; Lee, KW; Park, HT; Shin, JH, 2009)
" This study assessed the relationship between free thyroxine and clinical features of metabolic syndrome (MS)."3.73Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population. ( Lai, WA; Lin, SY; Liu, PH; Sheu, WH; Wang, YY, 2005)
"Subclinical hypothyroidism is defined by elevated serum thyrotropin in presence of normal free thyroid hormones."2.55Subclinical hypothyroidism, lipid metabolism and cardiovascular disease. ( Delitala, AP; Delitala, G; Fanciulli, G; Maioli, M, 2017)
"The major outcome was the occurrence of NAFLD, diagnosed based on the findings of abdominal ultrasonography."1.51The relationship between nonalcoholic fatty liver disease and pediatric congenital hypothyroidism patients. ( Chen, MY; Chen, SY; Chou, YY; Pan, YW; Tsai, MC; Yang, YJ, 2019)
"Thyroid disease and metabolic syndrome are both associated with cardiovascular disease."1.51The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults. ( Jeon, YK; Kim, BH; Kim, EH; Kim, IJ; Kim, JH; Kim, JM; Kim, M; Kim, SS; Kim, YK; Lee, H, 2019)
"Metabolic syndrome was defined based on the NCEP-ATPIII criteria."1.46Thyroid, cortisol and growth hormone levels in adult Nigerians with metabolic syndrome. ( Egbuagha, EU; Olowoselu, OF; Oshodi, TA; Udenze, IC, 2017)
"Euthyroid subjects with suspected NAFLD are characterized by higher FT3, lower FT4 and higher FT3/FT4 ratio, probably consequent to central obesity."1.46Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study. ( Amini, M; Blokzijl, H; Dullaart, RP; Faber, KN; Schreuder, TC; van den Berg, EH; van Tienhoven-Wind, LJ, 2017)
"Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes."1.46Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017)
"Hypothyroidism was considered at a thyroid stimulating hormone level ≥ 4."1.43FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. ( Ahbab, S; Ataoğlu, HE; Çetin, F; Gökmen, FY; Mamaç, RY; Türker, BÇ; Türker, F; Yenigün, M, 2016)
"We studied 30 GH naive patients with Sheehan's syndrome (SS) on standard replacement therapy and compared with healthy age, BMI and parity matched controls."1.42Insulin resistance, metabolic syndrome and chronic low grade inflammation in Sheehan's syndrome on standard replacement therapy: a case control study. ( Bhat, MA; Laway, BA; Mubarik, I; Shah, ZA; Wani, AI, 2015)
"Using ultrasound, a diagnosis of NAFLD was made in subjects without a history of excessive alcohol consumption or liver diseases."1.42Thyroid function is associated with non-alcoholic fatty liver disease in euthyroid subjects. ( Gu, H; Sui, J; Tao, Y; Wu, J, 2015)
"Conventional risk factors for NAFLD were assessed as well as serum levels of TSH, FT3 and FT4."1.42Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects. ( Guan, L; Guan, Q; Jiang, Q; Jiang, Z; Lin, H; Liu, G; Yu, C; Zhang, N; Zhang, X; Zhang, Y; Zheng, X, 2015)
"Non-alcoholic fatty liver disease (NAFLD) is one of the most common disorders of the liver worldwide."1.42Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years. ( Boehm, BO; Denzer, C; Graeter, T; Greinert, A; Haenle, MM; Holzner, D; Koenig, W; Kratzer, W; Ludwig, U; Mason, RA; Oeztuerk, S, 2015)
"Metabolic syndrome has been associated with nodular goiter."1.42Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome. ( Barreto, A; Blanc, E; Brenta, G; Brodschi, D; Cejas, C; Faingold, C; Fossati, P; Musso, C; Nepote, A; Ponce, C; Salgado, P; Schnitman, M, 2015)
"NAFLD was diagnosed by conventional ultrasound examination."1.40Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease. ( Aydın, S; Cesur, Y; Gökçe, S; Özgen, IT; Torun, E, 2014)
"Metabolic syndrome was determined by definition of the Joint Interim Statement adjusted for the Iranian population."1.40Serum free thyroxine concentration is associated with metabolic syndrome in euthyroid subjects. ( Amouzegar, A; Azizi, F; Mehran, L; Moayedi, M; Tohidi, M, 2014)
"Patients with primary hypothyroidism who are controlled on stable L-T4 replacement therapy were recruited and thyroid function test was performed."1.39The role of type II deiodinase polymorphisms in clinical management of hypothyroid patients treated with levothyroxine. ( Al-azzam, SI; Al-Azzeh, O; Alkhateeb, AM; Alzoubi, KH; Khabour, OF, 2013)
"Metabolic syndrome was diagnosed in 122 patients (58%)."1.38Association of metabolic syndrome parameters with TT3 and FT3/FT4 ratio in obese Turkish population. ( Abanonu, GB; Tarcin, O; Yazici, D, 2012)
"Hypothyroidism is closely associated with NAFLD independently of known metabolic risk factors, confirming a relevant clinical relationship between these two diseases."1.38Non-alcoholic fatty liver disease across the spectrum of hypothyroidism. ( Chung, GE; Kim, D; Kim, W; Kim, YJ; Lee, HS; Park, MJ; Yim, JY; Yoon, JH, 2012)
"The metabolic syndrome was defined according to National Cholesterol Education Program's Adult Treatment Panel III criteria."1.34Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects. ( Bakker, SJ; Gans, RO; Links, TP; Roos, A; Wolffenbuttel, BH, 2007)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (16.98)29.6817
2010's37 (69.81)24.3611
2020's7 (13.21)2.80

Authors

AuthorsStudies
Shin, KA1
Kim, EJ1
Wu, Z1
Jiang, Y1
Zhou, D1
Chen, S1
Zhao, Y2
Zhang, H1
Liu, Y1
Li, X1
Wang, W1
Zhang, J1
Kang, X1
Tao, L1
Gao, B1
Guo, X1
Calcaterra, V1
Gazzarri, A1
De Silvestri, A1
Madia, C1
Baldassarre, P1
Rossi, V1
Garella, V1
Zuccotti, G1
Pan, YW1
Tsai, MC1
Yang, YJ1
Chen, MY1
Chen, SY1
Chou, YY1
Dutka, R1
Chmyr, N1
Svitlyk, H1
Leontieva, Z1
Yang, Q1
Dong Li, W1
Yan Wan, H1
Yi Cao, H1
Punda, A1
Škrabić, V1
Torlak, V1
Gunjača, I1
Boraska Perica, V1
Kolčić, I1
Polašek, O1
Hayward, C1
Zemunik, T1
Matana, A1
Ding, X1
Zhu, CY1
Li, R1
Wu, LP1
Wang, Y2
Hu, SQ1
Liu, YM1
Zhao, FY1
Zhang, M1
He, MQ1
Chen, ZY1
Shi, BY1
Berahman, H1
Elmieh, A1
Fadaei Chafy, MR1
Park, SY1
Park, SE1
Jung, SW1
Jin, HS1
Park, IB1
Ahn, SV1
Lee, S1
Udenze, IC1
Olowoselu, OF1
Egbuagha, EU1
Oshodi, TA1
Ahirwar, AK1
Singh, A1
Jain, A1
Patra, SK1
Goswami, B1
Bhatnagar, MK1
Bhattacharjee, J1
Gu, Y1
Zhang, Q1
Liu, L1
Meng, G1
Yao, Z1
Wu, H1
Xia, Y1
Bao, X1
Shi, H1
Wang, H1
Sun, S1
Wang, X1
Zhou, M1
Jia, Q1
Song, K1
Niu, K1
Miljić, D1
Popovic, V1
Kim, EY1
Chang, Y1
Lee, KH1
Yun, JS1
Park, YL1
Park, CH1
Ahn, J1
Shin, H1
Ryu, S1
Kim, JM1
Kim, BH1
Lee, H1
Kim, EH1
Kim, M1
Kim, JH1
Jeon, YK1
Kim, SS1
Kim, IJ1
Kim, YK1
Nakajima, Y1
Yamada, M1
Akuzawa, M1
Ishii, S1
Masamura, Y1
Satoh, T1
Hashimoto, K1
Negishi, M1
Shimomura, Y1
Kobayashi, I1
Andou, Y1
Mori, M1
Torun, E1
Özgen, IT1
Gökçe, S1
Aydın, S1
Cesur, Y1
Bhat, MA1
Laway, BA1
Shah, ZA1
Wani, AI1
Mubarik, I1
Mehran, L1
Amouzegar, A1
Tohidi, M1
Moayedi, M1
Azizi, F1
Krysicki, M1
Jaworska, M1
Popowicz, B1
Jankiewicz-Wika, J1
Klencki, M1
Słowińska-Klencka, D1
Tao, Y1
Gu, H1
Wu, J1
Sui, J1
Liu, G1
Zheng, X1
Guan, L1
Jiang, Z1
Lin, H1
Jiang, Q1
Zhang, N1
Zhang, Y1
Zhang, X1
Yu, C1
Guan, Q1
van Tienhoven-Wind, LJ2
Dullaart, RP2
Blanc, E1
Ponce, C1
Brodschi, D1
Nepote, A1
Barreto, A1
Schnitman, M1
Fossati, P1
Salgado, P1
Cejas, C1
Faingold, C1
Musso, C1
Brenta, G1
Ludwig, U1
Holzner, D1
Denzer, C1
Greinert, A1
Haenle, MM1
Oeztuerk, S1
Koenig, W1
Boehm, BO1
Mason, RA1
Kratzer, W1
Graeter, T1
Uzcátegui, E1
Valery, L1
Uzcátegui, L1
Gómez Pérez, R1
Marquina, D1
Baptista, T1
Zhao, MJ1
Yang, YH1
Zhou, SJ1
Yuan, D1
Lu, WH1
Zhang, BL1
Ji, YD1
Wang, CG1
Gu, YQ1
Gökmen, FY1
Ahbab, S1
Ataoğlu, HE1
Türker, BÇ1
Çetin, F1
Türker, F1
Mamaç, RY1
Yenigün, M1
Huang, CY1
Hwang, LC1
Harbuwono, DS1
Pramono, LA1
Hendarto, H1
Subekti, I1
Le, TN1
Celi, FS1
Wickham, EP1
Delitala, AP1
Fanciulli, G1
Maioli, M1
Delitala, G1
van den Berg, EH1
Amini, M1
Schreuder, TC1
Faber, KN1
Blokzijl, H1
Askari, A1
Ehrampoush, E1
Homayounfar, R1
Bahramali, E1
Farjam, M1
Cerit, L1
De Pergola, G1
Giorgino, F1
Benigno, R1
Guida, P1
Giorgino, R1
Park, HT1
Cho, GJ1
Ahn, KH1
Shin, JH1
Hong, SC1
Kim, T1
Hur, JY1
Kim, YT1
Lee, KW1
Kim, SH1
Demidova, TIu1
Galieva, OR1
Alevizaki, M1
Saltiki, K1
Voidonikola, P1
Mantzou, E1
Papamichael, C1
Stamatelopoulos, K1
Garduño-Garcia, Jde J1
Alvirde-Garcia, U1
López-Carrasco, G1
Padilla Mendoza, ME1
Mehta, R1
Arellano-Campos, O1
Choza, R1
Sauque, L1
Garay-Sevilla, ME1
Malacara, JM1
Gomez-Perez, FJ1
Aguilar-Salinas, CA1
Wang, JY1
Wang, CY1
Pei, D1
Lai, CC1
Chen, YL1
Wu, CZ1
Chang, YL1
Hsu, CH1
Pei, C1
Tang, SH1
Park, SB1
Choi, HC1
Joo, NS1
Tarcin, O2
Abanonu, GB1
Yazici, D1
Chung, GE1
Kim, D1
Kim, W1
Yim, JY1
Park, MJ1
Kim, YJ1
Yoon, JH1
Lee, HS1
Kouidhi, S1
Berhouma, R1
Ammar, M1
Rouissi, K1
Jarboui, S1
Clerget-Froidevaux, MS1
Seugnet, I1
Abid, H1
Bchir, F1
Demeneix, B1
Guissouma, H1
Elgaaied, AB1
Topsakal, S1
Yerlikaya, E1
Akin, F1
Kaptanoglu, B1
Erürker, T1
Al-azzam, SI1
Alkhateeb, AM1
Al-Azzeh, O1
Alzoubi, KH1
Khabour, OF1
Aldhahi, W1
Mun, E1
Goldfine, AB1
Lin, SY1
Wang, YY1
Liu, PH1
Lai, WA1
Sheu, WH1
Roos, A1
Bakker, SJ1
Links, TP1
Gans, RO1
Wolffenbuttel, BH1
Duntas, LH1
Wartofsky, L1
Kim, BJ1
Kim, TY1
Koh, JM1
Kim, HK1
Park, JY1
Lee, KU1
Shong, YK1
Kim, WB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Predictors of NAFLD in Patient of Hypothyroidism[NCT05813301]100 participants (Anticipated)Observational2023-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for thyroxine and Metabolic Syndrome

ArticleYear
Metabolic Syndrome in Hypopituitarism.
    Frontiers of hormone research, 2018, Volume: 49

    Topics: Comorbidity; Female; Growth Hormone; Hormone Replacement Therapy; Humans; Hydrocortisone; Hypopituit

2018
Low-normal thyroid function and the pathogenesis of common cardio-metabolic disorders.
    European journal of clinical investigation, 2015, Volume: 45, Issue:5

    Topics: Asymptomatic Diseases; Cardiovascular Diseases; Cholesterol, LDL; Humans; Hypothyroidism; Insulin Re

2015
Subclinical hypothyroidism, lipid metabolism and cardiovascular disease.
    European journal of internal medicine, 2017, Volume: 38

    Topics: Blood Pressure; Cardiovascular Diseases; Carotid Intima-Media Thickness; Humans; Hypothyroidism; Lip

2017
Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence?
    Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation Disorders; Cardiovascular Diseases; Humans; Hyperc

2007

Trials

1 trial available for thyroxine and Metabolic Syndrome

ArticleYear
The effect of water-based rhythmic exercise training on glucose homeostasis and thyroid hormones in postmenopausal women with metabolic syndrome.
    Hormone molecular biology and clinical investigation, 2021, Jun-09, Volume: 42, Issue:2

    Topics: Aged; Blood Glucose; Exercise; Exercise Therapy; Female; Humans; Metabolic Syndrome; Postmenopause;

2021

Other Studies

48 other studies available for thyroxine and Metabolic Syndrome

ArticleYear
Association between thyroid hormone and components of metabolic syndrome in euthyroid Korean adults: A population-based study.
    Medicine, 2021, Dec-23, Volume: 100, Issue:51

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Hypertension; Hypertriglyceridemia; Male; Metabolic

2021
Sex-specific Association of Subclinical Hypothyroidism With Incident Metabolic Syndrome: A Population-based Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2022, 05-17, Volume: 107, Issue:6

    Topics: Adult; Cohort Studies; Female; Humans; Hypothyroidism; Male; Metabolic Syndrome; Middle Aged; Risk F

2022
Thyroid function, sensitivity to thyroid hormones, and metabolic syndrome in euthyroid children and adolescents with Down syndrome.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:11

    Topics: Adolescent; Child; Cholesterol, HDL; Down Syndrome; Humans; Metabolic Syndrome; Thyroid Gland; Thyro

2023
The relationship between nonalcoholic fatty liver disease and pediatric congenital hypothyroidism patients.
    The Kaohsiung journal of medical sciences, 2019, Volume: 35, Issue:12

    Topics: Adolescent; Adult; Blood Glucose; Child; Congenital Hypothyroidism; Cross-Sectional Studies; Female;

2019
PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS.
    Georgian medical news, 2019, Issue:297

    Topics: Biomarkers; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Hydrocortisone; Meta

2019
Association of thyroid hormones with metabolic syndrome and its components in postmenopausal Chinese women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Asian People; China; Cross-Sectional Studies; Female; Humans; Metabo

2020
Thyroid hormone levels are associated with metabolic components: a cross-sectional study.
    Croatian medical journal, 2020, Jul-05, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Cholesterol; Cross-Section

2020
Lower normal free thyroxine is associated with a higher risk of metabolic syndrome: a retrospective cohort on Chinese population.
    BMC endocrine disorders, 2021, Mar-04, Volume: 21, Issue:1

    Topics: Adult; Aged; China; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Metabolic Syndrome; Mid

2021
Free triiodothyronine/free thyroxine ratio rather than thyrotropin is more associated with metabolic parameters in healthy euthyroid adult subjects.
    Clinical endocrinology, 2017, Volume: 87, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Healthy Volunteers; Hum

2017
Thyroid, cortisol and growth hormone levels in adult Nigerians with metabolic syndrome.
    The Pan African medical journal, 2017, Volume: 26

    Topics: Adult; Aged; Blood Pressure; Case-Control Studies; Cross-Sectional Studies; Female; Growth Hormone;

2017
Raised TSH is associated with endothelial dysfunction in Metabolic Syndrome: A case control study.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2017, Dec-01, Volume: 55, Issue:4

    Topics: Adult; Case-Control Studies; Endothelin-1; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay;

2017
The association between thyroid function and incidence of metabolic syndrome in euthyroid subjects: Tianjin chronic low-grade systemic inflammation and health cohort study.
    Clinical endocrinology, 2018, Volume: 88, Issue:5

    Topics: Adult; China; Cohort Studies; Female; Humans; Incidence; Inflammation; Male; Metabolic Syndrome; Mid

2018
Serum concentration of thyroid hormones in abnormal and euthyroid ranges and breast cancer risk: A cohort study.
    International journal of cancer, 2019, 12-15, Volume: 145, Issue:12

    Topics: Adult; Breast; Breast Neoplasms; Cohort Studies; Female; Humans; Metabolic Syndrome; Middle Aged; Pr

2019
The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults.
    Diabetes & metabolism journal, 2019, Volume: 43, Issue:6

    Topics: Adult; Aged; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Iodi

2019
Subclinical hypothyroidism and indices for metabolic syndrome in Japanese women: one-year follow-up study.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Cholesterol, LDL; Cross-Sectional Studies; Female; Fol

2013
Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease.
    Journal of clinical research in pediatric endocrinology, 2014, Volume: 6, Issue:1

    Topics: Adolescent; Anthropometry; Biomarkers; Case-Control Studies; Child; Fatty Liver; Female; Follow-Up S

2014
Insulin resistance, metabolic syndrome and chronic low grade inflammation in Sheehan's syndrome on standard replacement therapy: a case control study.
    Pituitary, 2015, Volume: 18, Issue:3

    Topics: Adult; Age Factors; Biomarkers; Blood Glucose; Body Mass Index; Case-Control Studies; Chronic Diseas

2015
Serum free thyroxine concentration is associated with metabolic syndrome in euthyroid subjects.
    Thyroid : official journal of the American Thyroid Association, 2014, Volume: 24, Issue:11

    Topics: Adult; Body Mass Index; Cross-Sectional Studies; Female; Humans; Insulin; Insulin Resistance; Iran;

2014
[The incidence of hypothyroidism symptoms and risk factors for cardiovascular events in subclinical hypothyroidism].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2014, Volume: 37, Issue:217

    Topics: Adult; Blood Glucose; Blood Pressure Determination; Body Mass Index; Cardiovascular Diseases; Choles

2014
Thyroid function is associated with non-alcoholic fatty liver disease in euthyroid subjects.
    Endocrine research, 2015, Volume: 40, Issue:2

    Topics: Adult; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Non-alcoholic

2015
Free triiodothyronine levels are positively associated with non-alcoholic fatty liver disease in euthyroid middle-aged subjects.
    Endocrine research, 2015, Volume: 40, Issue:4

    Topics: Adult; China; Comorbidity; Female; Humans; Male; Menopause; Metabolic Syndrome; Middle Aged; Non-alc

2015
Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:5

    Topics: Aged; Aged, 80 and over; Anthropometry; Argentina; Body Mass Index; Cohort Studies; Cross-Sectional

2015
Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years.
    BMC endocrine disorders, 2015, Aug-15, Volume: 15

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cross-Secti

2015
Prevalence of the metabolic syndrome, insulin resistance index, leptin and thyroid hormone levels in the general population of Merida (Venezuela).
    Investigacion clinica, 2015, Volume: 56, Issue:2

    Topics: Adult; Cross-Sectional Studies; Female; Humans; Insulin Resistance; Leptin; Male; Metabolic Syndrome

2015
[Serum homocysteine and metabolic syndrome in middle-aged and elderly men].
    Zhonghua nan ke xue = National journal of andrology, 2016, Volume: 22, Issue:2

    Topics: Adult; Aged; Blood Pressure; Body Mass Index; Homocysteine; Humans; Luteinizing Hormone; Male; Metab

2016
FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism.
    Clinics (Sao Paulo, Brazil), 2016, Volume: 71, Issue:4

    Topics: Adult; Biomarkers; Cholesterol; Female; Humans; Hypothyroidism; Insulin Resistance; Male; Metabolic

2016
THE ASSOCIATION OF THYROID HORMONES AND TSH WITH THE METABOLIC SYNDROME IN EUTHYROID TAIWANESE INDIVIDUALS.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2016, Volume: 22, Issue:11

    Topics: Adult; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Taiwan; Thyrotropin; Thyroxine; Triiod

2016
Improvement of Metabolic Parameters Resulted from Levothyroxine Therapy in Hypothyroid Type 2 Diabetes Mellitus Patient.
    Acta medica Indonesiana, 2016, Volume: 48, Issue:2

    Topics: Blood Glucose; Blood Pressure; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, T

2016
Thyrotropin Levels Are Associated with Cardiometabolic Risk Factors in Euthyroid Adolescents.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:10

    Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Cohort Studies; Cross-Sectional Studies; Dys

2016
Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: the Lifelines Cohort Study.
    Metabolism: clinical and experimental, 2017, Volume: 67

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Female; Humans;

2017
Serum insulin in pathogenesis and treatment of osteoarthritis.
    Medical hypotheses, 2017, Volume: 99

    Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression;

2017
Thyroid disorders might be related to metabolic syndrome components.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:2

    Topics: Adult; Diet, Fat-Restricted; Humans; Metabolic Syndrome; Thyroid Gland; Thyroxine; Triglycerides

2017
Independent influence of insulin, catecholamines, and thyroid hormones on metabolic syndrome.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Aged; Blood Glucose; Case-Control Studies; Catecholamines; Cohort Studies; Epinep

2008
Thyroid stimulating hormone is associated with metabolic syndrome in euthyroid postmenopausal women.
    Maturitas, 2009, Mar-20, Volume: 62, Issue:3

    Topics: Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholesterol; Cross-Sectional Studies; Female

2009
[The role of thyroid hypofunction in development of metabolic syndrome].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:4

    Topics: Blood Pressure; Body Mass Index; Body Weight; Female; Hormone Replacement Therapy; Humans; Hypothyro

2009
Free thyroxine is an independent predictor of subcutaneous fat in euthyroid individuals.
    European journal of endocrinology, 2009, Volume: 161, Issue:3

    Topics: Adiposity; Adult; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Me

2009
TSH and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects.
    European journal of endocrinology, 2010, Volume: 163, Issue:2

    Topics: Biomarkers; Blood Glucose; Cholesterol, HDL; Cross-Sectional Studies; Female; Hispanic or Latino; Hu

2010
Association between thyroid function and metabolic syndrome in elderly subjects.
    Journal of the American Geriatrics Society, 2010, Volume: 58, Issue:8

    Topics: Aged; Blood Pressure; Body Mass Index; Cholesterol, HDL; Female; Humans; Linear Models; Male; Metabo

2010
The relation of thyroid function to components of the metabolic syndrome in Korean men and women.
    Journal of Korean medical science, 2011, Volume: 26, Issue:4

    Topics: Adult; Asian People; Blood Glucose; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Female; Foll

2011
Association of metabolic syndrome parameters with TT3 and FT3/FT4 ratio in obese Turkish population.
    Metabolic syndrome and related disorders, 2012, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Body Mass Index; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Obe

2012
Non-alcoholic fatty liver disease across the spectrum of hypothyroidism.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Adult; Alanine Transaminase; Body Mass Index; Cross-Sectional Studies; Fatty Liver; Female; Humans;

2012
Relationship of thyroid function with obesity and type 2 diabetes in euthyroid Tunisian subjects.
    Endocrine research, 2013, Volume: 38, Issue:1

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Resistance; Male; Metabol

2013
Relation with HOMA-IR and thyroid hormones in obese Turkish women with metabolic syndrome.
    Eating and weight disorders : EWD, 2012, Volume: 17, Issue:1

    Topics: Adult; Aged; Autoantibodies; Blood Pressure; Body Mass Index; Cholesterol; Cross-Sectional Studies;

2012
The role of type II deiodinase polymorphisms in clinical management of hypothyroid patients treated with levothyroxine.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2013, Volume: 121, Issue:5

    Topics: Adult; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Humans; Hypertension; Hypothyroidi

2013
Portal and peripheral cortisol levels in obese humans.
    Diabetologia, 2004, Volume: 47, Issue:5

    Topics: Adult; Diabetes Complications; Female; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Insulin

2004
Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:11

    Topics: Adult; Age Distribution; Asian People; Female; Humans; Hypertriglyceridemia; Male; Metabolic Syndrom

2005
Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:2

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Female; Homeostasis; Human

2007
Relationship between serum free T4 (FT4) levels and metabolic syndrome (MS) and its components in healthy euthyroid subjects.
    Clinical endocrinology, 2009, Volume: 70, Issue:1

    Topics: Abdominal Fat; Adult; Blood Glucose; Blood Pressure; Cholesterol, HDL; Female; Humans; Male; Metabol

2009