thyroxine has been researched along with Metabolic Diseases in 24 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subclinical hypothyroidism (also known as compensated hypothyroidism or mild hypothyroidism) is a condition associated with a raised serum concentration of thyroid stimulating hormone (TSH) but a normal serum free thyroxine (FT4)." | 4.95 | Subclinical hypothyroidism: Should we treat? ( Redford, C; Vaidya, B, 2017) |
| "Overweight/obesity mediated the associations of MAFLD with triiodothyronine (T3), free triiodothyronine (FT3), free thyroxine (FT4), and the mediator accounted for 46." | 4.31 | The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes. ( Cao, L; Chen, X; Fan, H; Li, L; Liu, Z; Suo, C; Zhang, T, 2023) |
| "Euthyroidism, primary hypothyroidism, and subclinical hypothyroidism were diagnosed in 47." | 1.91 | Clinical indicators that influence a clinician's decision to start L-thyroxine treatment in prematurity with transient hypothyroxinemia. ( Cakir, AD; Culpan, HC; Evliyaoglu, O; Kaya, N; Ozer, Y; Perk, Y; Vural, M; Yilmaz, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (62.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Barry, Y | 1 |
| Mandereau-Bruno, L | 1 |
| Bonaldi, C | 1 |
| Cheillan, D | 1 |
| Coutant, R | 1 |
| Léger, J | 1 |
| Regnault, N | 1 |
| Fan, H | 1 |
| Li, L | 1 |
| Liu, Z | 1 |
| Cao, L | 1 |
| Chen, X | 1 |
| Suo, C | 1 |
| Zhang, T | 1 |
| Yilmaz, A | 1 |
| Ozer, Y | 1 |
| Kaya, N | 1 |
| Cakir, AD | 1 |
| Culpan, HC | 1 |
| Perk, Y | 1 |
| Vural, M | 1 |
| Evliyaoglu, O | 1 |
| Nguyen, AB | 1 |
| Imamura, T | 1 |
| Besser, S | 1 |
| Rodgers, D | 1 |
| Chung, B | 1 |
| Raikhelkar, J | 1 |
| Kalantari, S | 1 |
| Smith, B | 1 |
| Sarswat, N | 1 |
| LaBuhn, C | 1 |
| Jeevanandam, V | 1 |
| Kim, G | 1 |
| Sayer, G | 1 |
| Uriel, N | 1 |
| Redford, C | 1 |
| Vaidya, B | 1 |
| Zhao, Y | 1 |
| Xue, Q | 1 |
| Su, X | 1 |
| Xie, L | 1 |
| Yan, Y | 1 |
| Steinman, AD | 1 |
| Pétervári, E | 1 |
| Koncsecskó-Gáspár, M | 1 |
| Balaskó, M | 1 |
| Székely, M | 1 |
| STANBURY, JB | 1 |
| KASSENAAR, AA | 1 |
| MEIJER, JW | 1 |
| LEVIN, ME | 1 |
| VANNOTTI, A | 1 |
| LEMARCHAND BERAUD, T | 1 |
| SCAZZIGA, BR | 1 |
| DEVISSCHER, M | 1 |
| BECKERS, C | 1 |
| KOENIG, MP | 1 |
| BAUMANN, T | 1 |
| SCHAERER, K | 1 |
| HERREN, C | 1 |
| Helenius, T | 1 |
| Liewendahl, K | 1 |
| Reiners, C | 1 |
| Hoffmann, R | 1 |
| Moll, E | 1 |
| Baum, K | 1 |
| Becker, W | 1 |
| Eilles, C | 1 |
| Gerhards, W | 1 |
| Schick, F | 1 |
| Spiegel, W | 1 |
| Wiedemann, W | 1 |
| Gonzales, E | 1 |
| Buyse, J | 1 |
| Sartori, JR | 1 |
| Loddi, MM | 1 |
| Decuypere, E | 1 |
| Porretti, S | 1 |
| Giavoli, C | 1 |
| Ronchi, C | 1 |
| Lombardi, G | 1 |
| Zaccaria, M | 1 |
| Valle, D | 1 |
| Arosio, M | 1 |
| Beck-Peccoz, P | 1 |
| Morrissey, KP | 1 |
| Reinwein, D | 1 |
| Hackenberg, K | 1 |
| Levin, SE | 1 |
| Klugman, LH | 1 |
| Schwille, PO | 1 |
| Sigel, A | 1 |
| Cropp, GJ | 1 |
| Myers, DN | 1 |
| Tezuka, U | 1 |
| Murakami, T | 1 |
| Mishiro, K | 1 |
| Fujino, M | 1 |
| Takeichi, O | 1 |
| Gorman, CA | 1 |
| Wahner, HW | 1 |
| Tauxe, WN | 1 |
| Smith, JD | 1 |
| Cagas, CR | 1 |
| Seely, JR | 1 |
| Neeman, J | 1 |
2 reviews available for thyroxine and Metabolic Diseases
| Article | Year |
|---|---|
Subclinical hypothyroidism: Should we treat?
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Humans; Hypothyroidism; Mental Disorders; Metabolic | 2017 |
Current concepts of gallstone formation.
Topics: Animals; Bile; Bile Acids and Salts; Cholecystectomy; Cholelithiasis; Cholesterol; Cholestyramine Re | 1975 |
22 other studies available for thyroxine and Metabolic Diseases
| Article | Year |
|---|---|
Prevalence and Determinants of Transient Congenital Hypothyroidism in Children With Eutopic Gland in France: A Retrospective Cohort Study.
Topics: Child; Congenital Hypothyroidism; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; | 2022 |
The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes.
Topics: Humans; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity; Overweight; Thyroid Hormones | 2023 |
Clinical indicators that influence a clinician's decision to start L-thyroxine treatment in prematurity with transient hypothyroxinemia.
Topics: Birth Weight; Gestational Age; Humans; Hypothyroidism; Infant; Infant, Newborn; Infant, Newborn, Dis | 2023 |
Metabolic Dysfunction in Continuous-Flow Left Ventricular Assist Devices Patients and Outcomes.
Topics: Aged; Comorbidity; Diabetes Mellitus; Endocrine System Diseases; Euthyroid Sick Syndromes; Female; G | 2019 |
Microcystin-LR induced thyroid dysfunction and metabolic disorders in mice.
Topics: Animals; Behavior, Animal; Biomarkers; Blood Glucose; Dose-Response Relationship, Drug; Eating; Endo | 2015 |
Increased thermoregulatory responsiveness in cold adapted but not in hyperthyroid hypermetabolic rats.
Topics: Acclimatization; Alprostadil; Animals; Body Temperature; Body Temperature Regulation; Cold Temperatu | 2003 |
The metabolism of iodotyrosines. I. The fate of mono- and di-iodotyrosine in normal subjects and in patients with various diseases.
Topics: Diabetes Mellitus; Endocrine System Diseases; Humans; Hyperthyroidism; Metabolic Diseases; Monoiodot | 1956 |
"Metabolic insufficiency": a double-blind study using triiodothyronine, thyroxine and a placebo: psychometric evaluation of the hypometabolic patient.
Topics: Double-Blind Method; Humans; Metabolic Diseases; Psychometrics; Thyroxine; Triiodothyronine | 1960 |
[PLASMATIC IODINATED PRODUCTS IN THYROID DISEASES].
Topics: Autoradiography; Blood Chemical Analysis; Chromatography; Diiodotyrosine; Goiter; Humans; Hyperthyro | 1964 |
[ENDEMIC GOITER].
Topics: Africa; Africa, Central; Autoradiography; Chromatography; Diiodotyrosine; Electrophoresis; Goiter; G | 1964 |
[CONGENITAL FAMILIAL DISORDER OF THYROID HORMONE SYNTHESIS. FAULTY OXIDATION FROM INORGANIC TO ORGANIC IODINE].
Topics: Adolescent; Child; Genetics, Medical; Goiter; Humans; Hypothyroidism; Infant; Iodine; Metabolic Dise | 1964 |
Improved dialysis method for free thyroxin in serum compared with five commercial radioimmunoassays in nonthyroidal illness and subjects with abnormal concentrations of thyroxin-binding globulin.
Topics: Adult; Aged; Dialysis; Female; Humans; Male; Metabolic Diseases; Middle Aged; Pregnancy; Pregnancy T | 1983 |
[Direct and indirect parameters for free thyroxine. II. Diagnostic accuracy in disorders of thyroid function and binding protein anomalies].
Topics: Adult; Carrier Proteins; Contraceptives, Oral; Female; Humans; Hyperthyroidism; Male; Metabolic Dise | 1983 |
Metabolic disturbances in male broilers of different strains. 2. Relationship between the thyroid and somatotropic axes with growth rate and mortality.
Topics: Aging; Animals; Chickens; Death; Growth Hormone; Insulin-Like Growth Factor I; Male; Metabolic Disea | 1999 |
Recombinant human GH replacement therapy and thyroid function in a large group of adult GH-deficient patients: when does L-T(4) therapy become mandatory?
Topics: Adult; Aged; Female; Hormone Replacement Therapy; Human Growth Hormone; Humans; Hypothyroidism; Male | 2002 |
[Euthyroid goiter with iodination defect and predominant formation of triiodothyronine, as a new form of iodine malutiligation].
Topics: Adult; Diagnosis, Differential; Diiodotyrosine; Female; Goiter; Goiter, Nodular; Humans; Iodine; Iod | 1970 |
Pendred's syndrome in South African Bantu brothers.
Topics: Black or African American; Black People; Child; Cholesterol; Deafness; Goiter; Humans; Male; Metabol | 1966 |
[Thyroxine and urinary calculi formation--an etiological connection? Preliminary report].
Topics: Animals; Hypothyroidism; Male; Metabolic Diseases; Rats; Thyroxine; Urinary Calculi | 1974 |
Physiological evidence of hypermetabolism in osteogenesis imperfecta.
Topics: Adolescent; Age Factors; Basal Metabolism; Body Temperature; Body Weight; Cardiac Output; Child; Chi | 1972 |
Congenital goiter found in a district of Omuro, Kochi, Shikoku, Japan: familial goiter caused by possible defect of diiodotyrosine coupling to form thyroxine.
Topics: Adolescent; Adult; Child; Child, Preschool; Diiodotyrosine; Female; Goiter; Humans; Iodine; Iodine I | 1971 |
Metabolic malingerers. Patients who deliberately induce or perpetuate a hypermetabolic or hypometabolic state.
Topics: Adult; Basal Metabolism; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Male; Maling | 1970 |
Defective iodide organification in "cryptothyroidism".
Topics: Child; Congenital Abnormalities; Congenital Hypothyroidism; Female; Goiter; Humans; Iodine; Metaboli | 1970 |