Page last updated: 2024-11-06

thyroxine and Malnutrition

thyroxine has been researched along with Malnutrition in 16 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Malnutrition: An imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement.

Research Excerpts

ExcerptRelevanceReference
"Iodine deficiency goiter can develop in children on a restrictive diet and most have normal thyroid function."8.12Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha. ( Quintos, JB; Sasidharan Pillai, S, 2022)
"Severe iodine deficiency during pregnancy has substantial hormonal consequences, such as fetal brain damage."8.12Can Mild-to-Moderate Iodine Deficiency during Pregnancy Alter Thyroid Function? Lessons from a Mother-Newborn Cohort. ( Almashanu, S; Anteby, EY; Avrahami-Benyounes, Y; Benbassat, C; Fytlovich, S; Gefel, D; Groisman, L; Ovadia, YS; Rorman, E; Rosen, SR; Shenhav, S; Zangen, S, 2022)
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."7.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
" Pregnancy induces physiological changes in thyroid homeostasis that are influenced by the iodine status."7.76Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population. ( Ares, S; Costeira, MJ; de Escobar, GM; Oliveira, P; Palha, JA; Roque, S, 2010)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."5.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)
"Iodine deficiency goiter can develop in children on a restrictive diet and most have normal thyroid function."4.12Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha. ( Quintos, JB; Sasidharan Pillai, S, 2022)
"Severe iodine deficiency during pregnancy has substantial hormonal consequences, such as fetal brain damage."4.12Can Mild-to-Moderate Iodine Deficiency during Pregnancy Alter Thyroid Function? Lessons from a Mother-Newborn Cohort. ( Almashanu, S; Anteby, EY; Avrahami-Benyounes, Y; Benbassat, C; Fytlovich, S; Gefel, D; Groisman, L; Ovadia, YS; Rorman, E; Rosen, SR; Shenhav, S; Zangen, S, 2022)
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."3.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
" Pregnancy induces physiological changes in thyroid homeostasis that are influenced by the iodine status."3.76Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population. ( Ares, S; Costeira, MJ; de Escobar, GM; Oliveira, P; Palha, JA; Roque, S, 2010)
"Undernutrition is a stressor with long-term consequences, and the effect of nutritional recovery on cortisol and thyroid hormone status is unknown."2.82Normal cortisol response to cold pressor test, but lower free thyroxine, after recovery from undernutrition. ( Clemente, AP; de Albuquerque, MP; Garcia, MC; Hoffman, DJ; Martins, VJ; Neves, AP; Sawaya, AL; Spadari, RC, 2016)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."1.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)
"Necrotizing stomatitis is more commonly encountered in malnourished children in developing countries, and may subsequently result in devastating facial defects and death."1.33Necrotizing stomatitis in the developed world. ( Buchanan, JA; Cedro, M; Hodgson, TA; Joseph, T; Mirdin, A; Porter, SR, 2006)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Paśko, P1
Okoń, K1
Prochownik, E1
Krośniak, M1
Francik, R1
Kryczyk-Kozioł, J1
Grudzińska, M1
Tyszka-Czochara, M1
Malinowski, M1
Sikora, J1
Galanty, A1
Zagrodzki, P1
Sasidharan Pillai, S1
Quintos, JB1
Shenhav, S1
Benbassat, C1
Gefel, D1
Zangen, S1
Rosen, SR1
Avrahami-Benyounes, Y1
Almashanu, S1
Groisman, L1
Rorman, E1
Fytlovich, S1
Anteby, EY1
Ovadia, YS1
Wan, S1
Jin, B1
Ren, B1
Boah, M1
Shen, H1
Kang, P1
Yao, Y1
Yang, J1
Shen, B1
Zhou, Z1
Pei, F1
Yavuz, D1
Sezer, S1
Yavuz, R1
Canoz, MB1
Altunoglu, A1
Altinoglu, A1
Elsürer, R1
Arat, Z1
Ozdemir, FN1
Martins, VJ1
Neves, AP1
Garcia, MC1
Spadari, RC1
Clemente, AP1
de Albuquerque, MP1
Hoffman, DJ1
Sawaya, AL1
Roberfroid, D1
Huybregts, L1
Lanou, H1
Henry, MC1
Meda, N1
Kolsteren F, P1
Costeira, MJ1
Oliveira, P1
Ares, S1
Roque, S1
de Escobar, GM2
Palha, JA1
Luca, F1
Goichot, B1
Brue, T1
Grazul-Bilska, AT1
Borowczyk, E1
Bilski, JJ1
Reynolds, LP1
Redmer, DA1
Caton, JS1
Vonnahme, KA1
GIACALONE, O1
ITO, T1
JOHNSON, RM1
Mahajan, SD1
Aalinkeel, R1
Singh, S1
Shah, P1
Gupta, N1
Kochupillai, N1
Pedraza, PE1
Obregon, MJ1
Escobar-Morreale, HF1
del Rey, FE1
Buchanan, JA1
Cedro, M1
Mirdin, A1
Joseph, T1
Porter, SR1
Hodgson, TA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso[NCT00642408]Phase 41,370 participants (Actual)Interventional2003-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for thyroxine and Malnutrition

ArticleYear
Relationship between mild iodine deficiency in pregnant women and thyroid function: A meta-analysis.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2023, Volume: 78

    Topics: Female; Humans; Iodine; Malnutrition; Pregnancy; Pregnant Women; Thyroid Function Tests; Thyroid Gla

2023
[Non thyroidal illnesses (NTIS)].
    Annales d'endocrinologie, 2010, Volume: 71 Suppl 1

    Topics: Acute Disease; Chronic Disease; Cytokines; Euthyroid Sick Syndromes; Humans; Hydrocortisone; Iodide

2010

Trials

2 trials available for thyroxine and Malnutrition

ArticleYear
Normal cortisol response to cold pressor test, but lower free thyroxine, after recovery from undernutrition.
    The British journal of nutrition, 2016, Jan-14, Volume: 115, Issue:1

    Topics: Adolescent; Area Under Curve; Child; Cold Temperature; Cross-Sectional Studies; Female; Growth Disor

2016
Effect of maternal multiple micronutrient supplements on cord blood hormones: a randomized controlled trial.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:6

    Topics: Adult; Burkina Faso; Dietary Supplements; Female; Fetal Blood; Fetal Growth Retardation; Hormones; H

2010

Other Studies

12 other studies available for thyroxine and Malnutrition

ArticleYear
The Impact of Kohlrabi Sprouts on Various Thyroid Parameters in Iodine Deficiency- and Sulfadimethoxine-Induced Hypothyroid Rats.
    Nutrients, 2022, Jul-08, Volume: 14, Issue:14

    Topics: Animals; Brassica; Glucosinolates; Hypothyroidism; Iodine; Malnutrition; Rats; Sulfadimethoxine; Thy

2022
Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Nov-25, Volume: 35, Issue:11

    Topics: Child; Female; Goiter; Goiter, Endemic; Humans; Hypothyroidism; Iodine; Malnutrition; Thyroglobulin;

2022
Can Mild-to-Moderate Iodine Deficiency during Pregnancy Alter Thyroid Function? Lessons from a Mother-Newborn Cohort.
    Nutrients, 2022, Dec-15, Volume: 14, Issue:24

    Topics: Adult; Female; Humans; Infant, Newborn; Iodine; Malnutrition; Mothers; Parturition; Pregnancy; Prote

2022
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Pro

2013
Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation.
    Iranian journal of kidney diseases, 2014, Volume: 8, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Female; Humans; Inflamm

2014
Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:9

    Topics: Adult; Female; Humans; Iodine; Longitudinal Studies; Malnutrition; Pregnancy; Thyroglobulin; Thyroid

2010
Overfeeding and underfeeding have detrimental effects on oocyte quality measured by in vitro fertilization and early embryonic development in sheep.
    Domestic animal endocrinology, 2012, Volume: 43, Issue:4

    Topics: Animals; Blastocyst; Body Composition; Body Weight; Embryo Culture Techniques; Embryonic Development

2012
[Effect of thyroxin, adrenaline and insulin on the limits of resistance to hypoalimentation and on the daily percental loss of body weight].
    Bollettino della Societa italiana di biologia sperimentale, 1952, Volume: 28, Issue:5

    Topics: Body Weight; Epinephrine; Humans; Insulin; Malnutrition; Thyroxine

1952
EFFECTS OF A NUTRITIONAL DEFICIENCY OF UNSATURATED FATS ON RAT LIVER MITOCHONDRIA.I. RESPIRATORY CONTROL AND ADENOSINE TRIPHOSPHATE-INORGANIC ORTHOPHOSPHATE EXCHANGE ACTIVITY.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenosine Triphosphate; Animals; Calcium; Deficiency Diseases; Dietary Fats; Dinitrophenols; Fats, U

1964
Thyroid hormone dysregulation in intrauterine growth retardation associated with maternal malnutrition and/or anemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2005, Volume: 37, Issue:10

    Topics: Anemia; Female; Fetal Blood; Fetal Growth Retardation; Fetal Nutrition Disorders; Humans; Infant, Ne

2005
Mechanisms of adaptation to iodine deficiency in rats: thyroid status is tissue specific. Its relevance for man.
    Endocrinology, 2006, Volume: 147, Issue:5

    Topics: Analysis of Variance; Animals; Body Weight; Female; Humans; Iodide Peroxidase; Iodine; Iodine Radioi

2006
Necrotizing stomatitis in the developed world.
    Clinical and experimental dermatology, 2006, Volume: 31, Issue:3

    Topics: Aged; Analgesics; Debridement; Deglutition Disorders; Developed Countries; Dietary Supplements; Ging

2006