thyroxine has been researched along with Liver Neoplasms in 76 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There have been reports of the use of levothyroxine or levothyroxine plus liothyronine for consumptive hypothyroidism caused by hepatic hemangiomas." | 7.85 | Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas. ( Hasegawa, Y; Higuchi, S; Takagi, M, 2017) |
| "The objective of this study was to determine the effects of sorafenib on TH levels in patients with hepatocellular carcinoma (HCC) and to evaluate possible mechanisms." | 7.85 | Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. ( Beukhof, CM; Bins, S; Chaker, L; de Herder, WW; de Rijke, YB; Mathijssen, RH; Peeters, RP; van Doorn, L; van Heerebeek, R; van Kemenade, FJ; Visser, TJ; Visser, WE, 2017) |
| " An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3)." | 7.76 | Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy. ( Dattani, MT; Langham, S; Mullis, PE; Peters, C, 2010) |
| "To determine the factors underlying the apparent reduction in binding ability of thyroxine-binding globulin in hepatocellular carcinoma, hormone-binding characteristics were further examined in patients with this disease and in control subjects." | 7.68 | Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease. ( Fagan, EA; Hutchinson, WL; Johnson, PJ; White, YS; Williams, R, 1991) |
| "In consumptive hypothyroidism associated with infantile hepatic hemangiomas (IHH), elevated reverse triiodothyronine (rT3) is known due to elevated D3." | 4.12 | Advantages of monitoring rT3 and dividing LT3 dose in the treatment of consumptive hypothyroidism associated with infantile hepatic hemangioma. ( Igaki, J; Kina, Y; Koki, M; Matsuoka, T; Numazawa, M; Tomari, K, 2022) |
| "Consumptive hypothyroidism due to cutaneous hemangioma and hepatic hemangioendothelioma can be managed with propranolol and low-dose sirolimus." | 4.12 | Severe consumptive hypothyroidism in hepatic hemangioendothelioma. ( Dubinski, I; Häberle, B; Küppers, J; Lurz, E; Schmid, I; Schmidt, H; Walther, A, 2022) |
| " The L-thyroxine replacement dose in patients with consumptive hypothyroidism is inappropriately higher than that in congenital hypothyroidism." | 3.88 | Severe consumptive hypothyroidism caused by multiple infantile hepatic haemangiomas. ( Demiral, M; Gundoğdu, E; Simsek, E, 2018) |
| "There have been reports of the use of levothyroxine or levothyroxine plus liothyronine for consumptive hypothyroidism caused by hepatic hemangiomas." | 3.85 | Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas. ( Hasegawa, Y; Higuchi, S; Takagi, M, 2017) |
| "The objective of this study was to determine the effects of sorafenib on TH levels in patients with hepatocellular carcinoma (HCC) and to evaluate possible mechanisms." | 3.85 | Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. ( Beukhof, CM; Bins, S; Chaker, L; de Herder, WW; de Rijke, YB; Mathijssen, RH; Peeters, RP; van Doorn, L; van Heerebeek, R; van Kemenade, FJ; Visser, TJ; Visser, WE, 2017) |
| " An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3)." | 3.76 | Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy. ( Dattani, MT; Langham, S; Mullis, PE; Peters, C, 2010) |
| " A 28-day-old boy with TSH level of 77 mIU/mL on neonatal screening and diagnosed as congenital hypothyroidism was started on L-thyroxine (L-T4) (11 μg/kg/day) therapy on the 21(th) day of life." | 3.76 | Hypothyroidism due to hepatic hemangioendothelioma: a case report. ( Ağladioğlu, SY; Aycan, Z; Baş, VN; Bozkurt, C; Çetinkaya, S; Kendirci, HN; Özdemir, S, 2010) |
| " This case emphasizes the importance of screening for hypothyroidism in patients with hemangiomas and the potential therapeutic benefit of prednisolone therapy in this condition." | 3.74 | Case report: consumptive hypothyroidism consequent to multiple infantile hepatic haemangiomas. ( Cho, YH; Hardwick, R; Howard, NJ; Howman-Giles, R; Lord, D; Mansour, A; Taplin, C, 2008) |
| " L-triiodothyronine and L-thyroxine stimulated hypoxia-induced Epo formation both in the kidney and in HepG2 cells in a dose-dependent fashion." | 3.69 | Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro. ( Fandrey, J; Frede, S; Jelkmann, W; Pagel, H; Wolff, M, 1994) |
| "To determine the factors underlying the apparent reduction in binding ability of thyroxine-binding globulin in hepatocellular carcinoma, hormone-binding characteristics were further examined in patients with this disease and in control subjects." | 3.68 | Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease. ( Fagan, EA; Hutchinson, WL; Johnson, PJ; White, YS; Williams, R, 1991) |
| "The significance of thyroxine (T4) uptake from serum in the assessment of thyroid status was evaluated, using human hepatoma (Hep G2) cells, in 30 euthyroid subjects, 6 hypothyroid and 19 hyperthyroid patients, and in 23 athyreotic cancer patients under T4 suppressive therapy." | 3.67 | Thyroxine uptake by human hepatoma cells from serum of patients submitted to long-term thyroxine suppressive therapy. ( Bartalena, L; Falcone, M; Martino, E; Pacchiarotti, A; Pinchera, A, 1988) |
| "In patients with liver diseases and with protein deficiency, there is a lack of synthesis of TBPA and RBP (deficiency in substrate and/or decrease in hepatic synthesis)." | 2.37 | [Prealbumin and retinol-binding protein]. ( Charrel, M; di Costanzo-Dufetel, J; Pontier, F; Romette, J, 1985) |
| "During future treatment of hypothyroidism, close attention to liver function may also be required to prevent a possible increased risk of HCC." | 1.72 | Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization study. ( Li, L; Lu, L; Sun, M; Wan, B, 2022) |
| "Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors." | 1.56 | A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas. ( Hong, KT; Kim, GB; Kim, YH; Ko, JS; Lee, YA; Lee, YJ; Shin, CH, 2020) |
| "The patient has hypoxemia due to abdominal distention during the follow-up period." | 1.46 | Beta blocker and steroid therapy in the treatment of infantile hepatic hemangioendothelioma. ( Bör, Ö; Düzenli Kar, Y; Kebapçı, M; Özdemir, ZC; Şöhret, NC, 2017) |
| "Liver hemangioendotheliomas are capable of producing an excess of the thyroid hormone inactivating enzyme, type-3 iodothyronine deiodinase." | 1.34 | Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation. ( Athanassaki, I; Balazs, AE; Gunn, SK; Haymond, MW; Huang, SA; Karaviti, LP; Tatevian, N, 2007) |
| "Other metastases--to the brain, kidneys, skin and liver are rare." | 1.33 | Hepatic metastasis of differentiated thyroid carcinoma. ( Kraft, O, 2005) |
| "In the Morris hepatoma bearing animals serum MCP-1 content was elevated while TNF-alpha, thyroxine and insulin concentrations were decreased." | 1.33 | Cachexia--induced cerebellar degeneration: involvement of serum TNF and MCP-1 in the course of experimental neoplastic disease. ( Michalak, S; Michałowska-Wender, G; Wender, M, 2006) |
| "It is postulated that this patient's hepatoma produced a substance stimulating thyroid-stimulating hormone synthesis and secretion with resultant inappropriate thyroid-stimulating hormone production and thyrotoxicosis." | 1.27 | Hepatocellular carcinoma: an unusual course with hyperthyroidism and inappropriate thyroid-stimulating hormone production. ( Helzberg, JH; Lukert, BP; McPhee, MS; Zarling, EJ, 1985) |
| "Similarly, the presence or absence of hepatic encephalopathy determined, and/or reflected, at least in part, the type of response observed." | 1.27 | Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease. ( Gavaler, JS; Sanghvi, A; Schade, RR; Tarter, R; Van Thiel, DH, 1986) |
| "Plasma T3 levels were reduced in both breast cancer group, but were reduced only in colonic cancer patients with systemic metastases." | 1.26 | Plasma thyronine levels in carcinoma of the breast and colon. ( Davis, TE; Rose, DP, 1981) |
| "Three cases of hepatocellular carcinoma are reported in young men who had been taking androgenic-anabolic steroids." | 1.25 | Androgen-induced hepatoma. ( Baird, PJ; Farrell, GC; Joshua, DE; Kronenberg, H; Perkins, KW; Uren, RF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (48.68) | 18.7374 |
| 1990's | 11 (14.47) | 18.2507 |
| 2000's | 11 (14.47) | 29.6817 |
| 2010's | 13 (17.11) | 24.3611 |
| 2020's | 4 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Numazawa, M | 1 |
| Tomari, K | 1 |
| Igaki, J | 1 |
| Koki, M | 1 |
| Kina, Y | 1 |
| Matsuoka, T | 1 |
| Walther, A | 1 |
| Häberle, B | 1 |
| Küppers, J | 1 |
| Lurz, E | 1 |
| Schmid, I | 1 |
| Schmidt, H | 1 |
| Dubinski, I | 1 |
| Lu, L | 1 |
| Wan, B | 1 |
| Li, L | 2 |
| Sun, M | 1 |
| Kim, YH | 1 |
| Lee, YA | 1 |
| Shin, CH | 1 |
| Hong, KT | 1 |
| Kim, GB | 1 |
| Ko, JS | 1 |
| Lee, YJ | 1 |
| Higuchi, S | 1 |
| Takagi, M | 1 |
| Hasegawa, Y | 1 |
| Beukhof, CM | 1 |
| van Doorn, L | 1 |
| Visser, TJ | 1 |
| Bins, S | 1 |
| Visser, WE | 1 |
| van Heerebeek, R | 1 |
| van Kemenade, FJ | 1 |
| de Rijke, YB | 1 |
| de Herder, WW | 1 |
| Chaker, L | 1 |
| Mathijssen, RH | 1 |
| Peeters, RP | 1 |
| Özdemir, ZC | 1 |
| Düzenli Kar, Y | 1 |
| Şöhret, NC | 1 |
| Kebapçı, M | 1 |
| Bör, Ö | 1 |
| P Katare, D | 1 |
| Malik, S | 1 |
| J Mani, R | 1 |
| Ranjpour, M | 1 |
| Jain, SK | 1 |
| Campbell, V | 1 |
| Beckett, R | 1 |
| Abid, N | 1 |
| Hoey, S | 1 |
| Simsek, E | 1 |
| Demiral, M | 1 |
| Gundoğdu, E | 1 |
| Anderson, L | 1 |
| Bhatia, V | 1 |
| Chi, JL | 1 |
| Li, CC | 1 |
| Xia, CQ | 1 |
| Ma, Y | 1 |
| Li, JH | 1 |
| Chen, Z | 1 |
| Chen, XL | 1 |
| Schmohl, KA | 1 |
| Müller, AM | 1 |
| Wechselberger, A | 1 |
| Rühland, S | 1 |
| Salb, N | 1 |
| Schwenk, N | 1 |
| Heuer, H | 1 |
| Carlsen, J | 1 |
| Göke, B | 1 |
| Nelson, PJ | 1 |
| Spitzweg, C | 1 |
| Mouat, F | 1 |
| Evans, HM | 1 |
| Cutfield, WS | 1 |
| Hofman, PL | 1 |
| Jefferies, C | 1 |
| Baginskaya, NV | 1 |
| Il'nitskaya, SI | 1 |
| Nikitenko, EV | 1 |
| Kaledin, VI | 1 |
| Peters, C | 1 |
| Langham, S | 1 |
| Mullis, PE | 1 |
| Dattani, MT | 1 |
| Çetinkaya, S | 1 |
| Kendirci, HN | 1 |
| Ağladioğlu, SY | 1 |
| Baş, VN | 1 |
| Özdemir, S | 1 |
| Bozkurt, C | 1 |
| Aycan, Z | 1 |
| Avagyan, S | 1 |
| Klein, M | 1 |
| Kerkar, N | 1 |
| Demattia, A | 1 |
| Blei, F | 1 |
| Lee, S | 1 |
| Rosenberg, HK | 1 |
| Arnon, R | 1 |
| Del Fabbro, E | 1 |
| Dev, R | 1 |
| Cabanillas, ME | 1 |
| Busaidy, NL | 1 |
| Rodriguez, EC | 1 |
| Bruera, E | 1 |
| Araya, Z | 1 |
| Tang, W | 1 |
| Wikvall, K | 1 |
| EMMELOT, P | 1 |
| BOS, CJ | 1 |
| BIELSCHOWSKY, F | 1 |
| BIELSCHOWSKY, M | 1 |
| FLETCHER, EK | 1 |
| LU, KH | 1 |
| YUAN, CC | 1 |
| WANG, PY | 1 |
| LE BRETON, E | 1 |
| CHAUVEAU, J | 1 |
| JACOB, A | 1 |
| MOULE, Y | 1 |
| REMOLINA, T | 1 |
| Kraft, O | 1 |
| Kalpatthi, R | 1 |
| Germak, J | 1 |
| Mizelle, K | 1 |
| Yeager, N | 1 |
| Michalak, S | 1 |
| Wender, M | 1 |
| Michałowska-Wender, G | 1 |
| Balazs, AE | 1 |
| Athanassaki, I | 1 |
| Gunn, SK | 1 |
| Tatevian, N | 1 |
| Huang, SA | 1 |
| Haymond, MW | 1 |
| Karaviti, LP | 1 |
| Cho, YH | 1 |
| Taplin, C | 1 |
| Mansour, A | 1 |
| Howman-Giles, R | 1 |
| Hardwick, R | 1 |
| Lord, D | 1 |
| Howard, NJ | 1 |
| Rosner, W | 1 |
| Aden, DP | 2 |
| Khan, MS | 1 |
| Stora, C | 2 |
| Aussel, C | 2 |
| Lafaurie, M | 2 |
| Formento, JL | 2 |
| Ordóñez-Llanos, J | 1 |
| Rodríguez-Espinosa, J | 1 |
| Gómez-Gerique, JA | 1 |
| Rose, DP | 1 |
| Davis, TE | 1 |
| Sorimachi, K | 3 |
| Yasumura, Y | 1 |
| Castelli, D | 1 |
| Djordjević, PB | 1 |
| Stajić, MS | 1 |
| Jovanović, P | 1 |
| Sinadinović, J | 1 |
| Fandrey, J | 3 |
| Pagel, H | 1 |
| Frede, S | 1 |
| Wolff, M | 1 |
| Jelkmann, W | 3 |
| Schwartz, ID | 1 |
| Freeman, AI | 1 |
| Grunt, JA | 1 |
| Crave, JC | 1 |
| Lejeune, H | 1 |
| Brébant, C | 1 |
| Baret, C | 1 |
| Pugeat, M | 1 |
| Crowe, TC | 1 |
| Cowen, NL | 1 |
| Loidl, NM | 1 |
| Topliss, DJ | 1 |
| Stockigt, JR | 1 |
| Barlow, JW | 1 |
| Kragie, L | 1 |
| Forrester, ML | 1 |
| Cody, V | 1 |
| McCourt, M | 1 |
| Brenner, B | 1 |
| Guglielmi, R | 1 |
| Pacella, CM | 1 |
| Dottorini, ME | 1 |
| Bizzarri, GC | 1 |
| Todino, V | 1 |
| Crescenzi, A | 1 |
| Rinaldi, R | 1 |
| Panunzi, C | 1 |
| Rossi, Z | 1 |
| Colombo, L | 1 |
| Papini, E | 1 |
| Kondo, T | 1 |
| Katoh, R | 1 |
| Omata, K | 1 |
| Oyama, T | 1 |
| Yagawa, A | 1 |
| Kawaoi, A | 1 |
| Benvenga, S | 1 |
| Lakshmanan, M | 1 |
| Trimarchi, F | 1 |
| Ayling, RM | 1 |
| Davenport, M | 1 |
| Hadzic, N | 1 |
| Metcalfe, R | 1 |
| Buchanan, CR | 1 |
| Howard, ER | 1 |
| Mieli-Vergani, G | 1 |
| Farrell, GC | 1 |
| Joshua, DE | 1 |
| Uren, RF | 1 |
| Baird, PJ | 1 |
| Perkins, KW | 1 |
| Kronenberg, H | 1 |
| Belanger, L | 1 |
| Hamel, D | 1 |
| Lachance, L | 1 |
| Dufour, D | 1 |
| Tremblay, M | 1 |
| Gagnon, PM | 1 |
| Cahnmann, HJ | 1 |
| Robbins, J | 1 |
| Carella, C | 1 |
| Del Vecchio-Blanco, C | 1 |
| Pisano, G | 1 |
| Biscaglia, G | 1 |
| Caporaso, N | 1 |
| Hutchinson, WL | 1 |
| White, YS | 1 |
| Fagan, EA | 1 |
| Johnson, PJ | 1 |
| Williams, R | 1 |
| Darby, IA | 1 |
| Bouhnik, J | 1 |
| Coezy, ED | 1 |
| Corvol, P | 1 |
| Seydel, FP | 1 |
| Siegers, CP | 1 |
| Plymate, SR | 2 |
| Hoop, RC | 1 |
| Jones, RE | 2 |
| Matej, LA | 2 |
| Kobayashi, M | 1 |
| Horiuchi, R | 1 |
| Hachisu, T | 1 |
| Takikawa, H | 1 |
| Friedl, KE | 1 |
| Bartalena, L | 1 |
| Martino, E | 1 |
| Falcone, M | 1 |
| Pacchiarotti, A | 1 |
| Pinchera, A | 1 |
| Helzberg, JH | 1 |
| McPhee, MS | 1 |
| Zarling, EJ | 1 |
| Lukert, BP | 1 |
| Murata, Y | 1 |
| Sarne, DH | 1 |
| Horwitz, AL | 1 |
| Lecocq, R | 1 |
| Knowles, BB | 1 |
| Refetoff, S | 1 |
| Van Thiel, DH | 1 |
| Tarter, R | 1 |
| Gavaler, JS | 1 |
| Schade, RR | 1 |
| Sanghvi, A | 1 |
| di Costanzo-Dufetel, J | 1 |
| Romette, J | 1 |
| Pontier, F | 1 |
| Charrel, M | 1 |
| Hamada, S | 1 |
| Nakagawa, T | 1 |
| Mori, T | 1 |
| Torizuka, K | 1 |
| Goodall, CM | 1 |
| Bellabarba, D | 1 |
| Inada, M | 1 |
| Varsano-Aharon, N | 1 |
| Sterling, K | 1 |
| Arcos, JC | 1 |
| Mathison, JB | 1 |
| Tison, MJ | 1 |
| Mouledoux, AM | 1 |
| Saliamon, LS | 1 |
| Wu, C | 1 |
| Morris, HP | 1 |
| Herzfeld, A | 1 |
| Greengard, O | 2 |
| Chandalia, HB | 1 |
| Boshell, BR | 1 |
| Dewey, HK | 1 |
| Pedersen, OL | 1 |
| Stroev, EA | 1 |
| Nikulin, AA | 1 |
| Hays, MT | 1 |
| Lewitus, Z | 1 |
| Fisher, ER | 1 |
| Fisher, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sirolimus in the Treatment for Propranolol-resistant Infantile Hepatic Hemangioendothelioma[NCT04406870] | Phase 4 | 36 participants (Anticipated) | Interventional | 2020-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and Liver Neoplasms
| Article | Year |
|---|---|
[Prealbumin and retinol-binding protein].
Topics: Aging; Androgens; Animals; Biological Transport; Chemical Phenomena; Chemistry; Estrogens; Female; F | 1985 |
75 other studies available for thyroxine and Liver Neoplasms
| Article | Year |
|---|---|
Advantages of monitoring rT3 and dividing LT3 dose in the treatment of consumptive hypothyroidism associated with infantile hepatic hemangioma.
Topics: Hemangioma; Humans; Hypothyroidism; Liver Neoplasms; Male; Thyroxine; Triiodothyronine; Triiodothyro | 2022 |
Severe consumptive hypothyroidism in hepatic hemangioendothelioma.
Topics: Hemangioendothelioma; Humans; Hypothyroidism; Infant; Liver Neoplasms; Male; Propranolol; Sirolimus; | 2022 |
Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization study.
Topics: Carcinoma, Hepatocellular; Genome-Wide Association Study; Humans; Hypothyroidism; Liver Neoplasms; M | 2022 |
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Cholestasis; Drug Therapy, Combination; Heart | 2020 |
Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas.
Topics: Hemangioma; Hormone Replacement Therapy; Humans; Hypothyroidism; Infant; Liver; Liver Neoplasms; Mal | 2017 |
Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma.
Topics: Aged; Amino Acid Transport Systems, Neutral; Animals; Antineoplastic Agents; Carcinoma, Hepatocellul | 2017 |
Beta blocker and steroid therapy in the treatment of infantile hepatic hemangioendothelioma.
Topics: Adrenergic beta-Antagonists; Glucocorticoids; Hemangioendothelioma; Hepatomegaly; Humans; Hypothyroi | 2017 |
Novel mutations in transthyretin gene associated with hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Amino Acid Sequence; Animals; Apolipoprotein A-I; Biomarkers, Tumor; Carcinom | 2018 |
Resolution of Consumptive Hypothyroidism Secondary to Infantile Hepatic Hemangiomatosis with a Combination of Propranolol and Levothyroxine
Topics: Adrenergic beta-Antagonists; Female; Hemangioma; Humans; Hypothyroidism; Infant; Infant, Newborn; Li | 2018 |
Severe consumptive hypothyroidism caused by multiple infantile hepatic haemangiomas.
Topics: Congenital Hypothyroidism; Hemangioma; Humans; Infant; Liver Neoplasms; Male; Prognosis; Severity of | 2018 |
Ipilimumab immune-related adverse reactions: a case report.
Topics: Antibodies, Monoclonal; Autoimmune Diseases; Female; Follow-Up Studies; Humans; Hydrocortisone; Hypo | 2013 |
Effect of (131)I gelatin microspheres on hepatocellular carcinoma in nude mice and its distribution after intratumoral injection.
Topics: Animals; Carcinoma, Hepatocellular; Gelatin; Hep G2 Cells; Heterografts; Humans; Injections, Intrale | 2014 |
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentia | 2015 |
Massive hepatic hemangioendothelioma and consumptive hypothyroidism.
Topics: Congenital Hypothyroidism; Female; Hemangioendothelioma; Hepatomegaly; Humans; Infant, Newborn; Live | 2008 |
Promoting effect of o-aminoazotoluene on hepatocarcinogenesis is accompanied by the increase in inflammatory and proliferative processes in liver tissue and decrease in the concentration of free thyroxin in the blood.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Diethylnitrosamine; Female; Inf | 2007 |
Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy.
Topics: Hemangioma; Humans; Hypothyroidism; Infant; Iodide Peroxidase; Liver Neoplasms; Male; Thyroxine; Tri | 2010 |
Hypothyroidism due to hepatic hemangioendothelioma: a case report.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Congenital Hypothyroidism; Hemangioendothelioma; Ho | 2010 |
Propranolol as a first-line treatment for diffuse infantile hepatic hemangioendothelioma.
Topics: Adrenergic beta-2 Receptor Antagonists; Antineoplastic Agents; Congenital Hypothyroidism; Drug Monit | 2013 |
Extreme hypothyroidism associated with sunitinib treatment for metastatic renal cancer.
Topics: Adult; Angiogenesis Inhibitors; Bone Neoplasms; Carcinoma, Renal Cell; Drug Resistance; Fatal Outcom | 2012 |
Hormonal regulation of the human sterol 27-hydroxylase gene CYP27A1.
Topics: Antineoplastic Agents, Hormonal; Base Sequence; Binding Sites; Carcinogens; Carcinoma, Hepatocellula | 2003 |
The effect of thyroxine on the swelling of mitochondria isolated from normal and neoplastic livers.
Topics: Animals; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; M | 1957 |
Investigations on the role of thyroxine in the development of hepatomas in hypophysectomized rats and pituitary dwarf mice.
Topics: Animals; Carcinoma, Hepatocellular; Dwarfism; Dwarfism, Pituitary; Hypophysectomy; Liver Neoplasms; | 1962 |
[THE EFFECT OF THYROXINE ON ISOLATED MITOCHONDRIA OF RAT LIVER AND HEPATOMA].
Topics: Adenosine Triphosphatases; Carcinoma, Hepatocellular; Enzyme Inhibitors; Liver; Liver Neoplasms; Met | 1964 |
[Action of thyroxin activated by coenzyme A on the glycolysis and respiration of slices of precancerous hepatic tissue].
Topics: Carbohydrate Metabolism; Carbohydrates; Cell Respiration; Coenzyme A; Coenzymes; Glycolysis; Liver; | 1959 |
Hepatic metastasis of differentiated thyroid carcinoma.
Topics: Aged; Aged, 80 and over; Carcinoma; Cell Differentiation; Humans; Iodine Radioisotopes; Liver; Liver | 2005 |
Thyroid abnormalities in infantile hepatic hemangioendothelioma.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; | 2007 |
Cachexia--induced cerebellar degeneration: involvement of serum TNF and MCP-1 in the course of experimental neoplastic disease.
Topics: Animals; Atrophy; Cachexia; Chemokine CCL2; Insulin; Liver Neoplasms; Liver Neoplasms, Experimental; | 2006 |
Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation.
Topics: Female; Hemangioendothelioma; Humans; Hypothyroidism; Infant; Liver Neoplasms; Liver Transplantation | 2007 |
Case report: consumptive hypothyroidism consequent to multiple infantile hepatic haemangiomas.
Topics: Developmental Disabilities; Glucocorticoids; Hemangioma; Humans; Hypothyroidism; Infant; Liver Neopl | 2008 |
Hormonal influences on the secretion of steroid-binding proteins by a human hepatoma-derived cell line.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cytosol; Estradiol; Humans; Liver; Liver Neoplasms; R | 1984 |
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Female; Liver Neoplasms; Neoplasms, Experimental | 1981 |
Antibody binding serum T3 in a patient with hepatocarcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Humans; Immunoglobulins; Liver Neoplasms; Male; Protein Binding; Ra | 1984 |
Plasma thyronine levels in carcinoma of the breast and colon.
Topics: Adult; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Middle Aged; | 1981 |
High affinity of triiodothyronine (T3) for nonphenolic ring deiodinase and high affinity of tetraiodothyroacetic acid (TETRAC) for phenolic ring deiodinase in cultured monkey hepatocarcinoma cells and in rat liver homogenates.
Topics: Animals; Cell Line; Chromatography, Ion Exchange; Haplorhini; Iodide Peroxidase; Liver; Liver Neopla | 1981 |
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide in the male rat.
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Male; Neoplasms, Experimental; Pituitary Gland; Rat | 1982 |
[Levels of the thyroid hormones, triiodothyronine and tetraiodothyronine, in the blood in liver diseases].
Topics: Humans; Liver Diseases; Liver Neoplasms; Thyroxine; Triiodothyronine | 1981 |
Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cells, Cultured; DNA; Dose-Response Relation | 1994 |
Serum concentrations of alpha-fetoprotein in children with primary hypothyroidism.
Topics: alpha-Fetoproteins; Child; Child, Preschool; Female; Hepatoblastoma; Humans; Hypothyroidism; Infant; | 1994 |
Differential effects of insulin and insulin-like growth factor I on the production of plasma steroid-binding globulins by human hepatoblastoma-derived (Hep G2) cells.
Topics: Carrier Proteins; Estradiol; Hepatoblastoma; Humans; Insulin; Insulin-Like Growth Factor Binding Pro | 1995 |
Down-regulation of thyroxine-binding globulin messenger ribonucleic acid by 3,5,3'-triiodothyronine in human hepatoblastoma cells.
Topics: Cell Line; Gene Expression Regulation, Neoplastic; Hepatoblastoma; Humans; Kinetics; Liver Neoplasms | 1995 |
Computer-assisted molecular modeling of benzodiazepine and thyromimetic inhibitors of the HepG2 iodothyronine membrane transporter.
Topics: Benzodiazepines; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Humans; Image Proce | 1994 |
Serum immunoreactive erythropoietin in hyper- and hypothyroidism: clinical observations related to cell culture studies.
Topics: Carcinoma, Hepatocellular; Erythropoietin; Hemoglobins; Humans; Hyperthyroidism; Hypothyroidism; Liv | 1994 |
Severe thyrotoxicosis due to hyperfunctioning liver metastasis from follicular carcinoma: treatment with (131)I and interstitial laser ablation.
Topics: Adenoma; Biopsy, Needle; Female; Humans; Iodine Radioisotopes; Laser Therapy; Liver; Liver Neoplasms | 1999 |
Incidentally detected liver metastasis of well-differentiated follicular carcinoma of the thyroid, mimicking ectopic thyroid.
Topics: Adenocarcinoma, Follicular; Cell Differentiation; Choristoma; Diagnosis, Differential; Female; Human | 2000 |
Carnitine is a naturally occurring inhibitor of thyroid hormone nuclear uptake.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Carnitine; Cell Line | 2000 |
Hepatic hemangioendothelioma associated with production of humoral thyrotropin-like factor.
Topics: Female; Hemangioendothelioma; Humans; Immunohistochemistry; Infant; Infant, Newborn; Liver Neoplasms | 2001 |
Androgen-induced hepatoma.
Topics: Adult; Anabolic Agents; Bone Neoplasms; Carcinoma, Hepatocellular; Cortisone; Cryptorchidism; Hemogl | 1975 |
Hormonal regulation of alpha1 foetoprotein.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Epinephrine; Feta | 1975 |
Formation and metabolism of 3',5'-diiodothyronine and 3,5-diiodothyronine by cultured monkey hepatocarcinoma cells.
Topics: Animals; Cell Line; Diiodothyronines; Haplorhini; Liver Neoplasms; Thyronines; Thyroxine; Triiodothy | 1979 |
Metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells. Nonphenolic ring dieodination and sulfation.
Topics: Carcinoma, Hepatocellular; Cell Line; Chromatography, Ion Exchange; Chromatography, Thin Layer; Hydr | 1977 |
[Reverse T3 (rT3), T3 and T4 in chronic aggressive hepatitis, cirrhosis and hepatic neoplasms].
Topics: Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Thyroxine; Triiodothyronine; T | 1978 |
Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease.
Topics: Adult; Carcinoma, Hepatocellular; Chronic Disease; Cytosol; Humans; Liver Diseases; Liver Neoplasms; | 1991 |
Thyroid hormone receptors and stimulation of angiotensinogen production in HepG2 cells.
Topics: Angiotensinogen; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Humans; K | 1991 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoi | 1990 |
Regulation of sex hormone-binding globulin production by growth factors.
Topics: Carcinoma, Hepatocellular; Cell Line; Dehydroepiandrosterone; Epidermal Growth Factor; Growth Substa | 1990 |
Dualistic effects of thyroid hormone on a human hepatoma cell line: inhibition of thyroxine-binding globulin synthesis and stimulation of alpha 1-acid glycoprotein synthesis.
Topics: Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Humans; Kinetics; Liver Neoplasms; Orosomucoid; | 1988 |
Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin.
Topics: Carcinoma, Hepatocellular; Cell Line; Depression, Chemical; Estradiol; Humans; Insulin; Liver Neopla | 1988 |
Thyroxine uptake by human hepatoma cells from serum of patients submitted to long-term thyroxine suppressive therapy.
Topics: Carcinoma, Hepatocellular; Humans; Hyperthyroidism; Hypothyroidism; Liver Neoplasms; Sex Hormone-Bin | 1988 |
Hepatocellular carcinoma: an unusual course with hyperthyroidism and inappropriate thyroid-stimulating hormone production.
Topics: Carcinoma, Hepatocellular; Female; Humans; Hyperthyroidism; Liver Neoplasms; Middle Aged; Paraneopla | 1985 |
Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
Topics: Carcinoma, Hepatocellular; Cell Line; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans; | 1985 |
Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease.
Topics: Carcinoma, Hepatocellular; Growth Hormone; Hepatic Encephalopathy; Humans; Liver Diseases; Liver Neo | 1986 |
Re-evaluation of thyroxine binding and free thyroxine in human serum by paper electrophoresis and equilibrium dialysis, and a new free thyroxine index.
Topics: Anorexia Nervosa; Carcinoma, Hepatocellular; Diabetes Mellitus; Dialysis; Electrophoresis; Female; G | 1970 |
Hepatic carcinogenesis in thyroidectomized rats: apparent blockade at the stage of initiation.
Topics: Animals; Carcinoma, Hepatocellular; Cortisone; Fluorenes; Liver Neoplasms; Neoplasms, Experimental; | 1966 |
Thyroxine transport and turnover in major nonthyroidal illness.
Topics: Adenocarcinoma; Adult; Aged; Biological Transport; Blood Proteins; Carcinoma; Carcinoma, Bronchogeni | 1968 |
Effect of feeding amino azo dyes on mitochondrial swelling and contraction. Kinetic evidence for deletion of membrane regulatory sites.
Topics: Adenosine Triphosphate; Animals; Arsenic; Carcinoma, Hepatocellular; Cell Membrane; Chloromercuriben | 1969 |
[Analysis of tumor transformation of tissue. I. Indications of the degree of autonomy and their appearance].
Topics: Adenoma; Adenosine Triphosphate; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Hepatocellular; | 1969 |
Responsiveness of glutamine-metabolizing enzymes in Morris hepatomas to metabolic modulations.
Topics: Adrenalectomy; Animal Feed; Animals; Animals, Laboratory; Carcinoma, Hepatocellular; Cell Line; Chro | 1970 |
Aspartate aminotransferase in fat tissues: changes with growth and hormones.
Topics: Aging; Animals; Aspartate Aminotransferases; Brain; Breast; Carcinoma 256, Walker; Carcinoma, Hepato | 1971 |
Hypoglycemia associated with extrapancreatic tumors. Report of two cases with studies on its pathogenesis.
Topics: Abdominal Neoplasms; Aged; Animals; Biological Assay; Blood Glucose; Carcinoma, Hepatocellular; Fatt | 1972 |
The effect of glucose ingestion on basal and induced enzyme levels in rat tissues.
Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animals; Brain; Carcinoma, Hepatocellular; Dietary Carbo | 1973 |
[Primary hepatocellular carcinoma with increased TBG and free thyroxine].
Topics: Aged; Carcinoma, Hepatocellular; Female; Humans; Immunoelectrophoresis; Liver Neoplasms; Radioimmuno | 1974 |
[Hormone regulation of the enzyme content of cells of transplantable liver cancer in rat].
Topics: Animals; Genes; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Malate Dehydrogenase; Neoplasms, Ex | 1974 |
Absorption of oral thyroxine in man.
Topics: Adult; Breast Neoplasms; Epinephrine; Female; Hepatitis; Humans; Hyperthyroidism; Intestinal Absorpt | 1968 |
An isotope test for portal hypertension.
Topics: Gold Colloid, Radioactive; Humans; Hypertension, Portal; Iodine Radioisotopes; Liver; Liver Cirrhosi | 1968 |
Experimental studies of factors influencing development of hepatic metastases. XVII. Role of thyroid.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Female; Hypothyroidism; Liver Neoplasms; | 1966 |