Page last updated: 2024-11-06

thyroxine and Liver Dysfunction

thyroxine has been researched along with Liver Dysfunction in 93 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"We report a patient with primary hypothyroidism, who developed hepatocellular injury due to levothyroxine, synthetic thyroxine."7.74Liver injury induced by levothyroxine in a patient with primary hypothyroidism. ( Aiso, M; Fukusato, T; Hojo, M; Ishii, T; Kawakami, T; Kawasaki, T; Kuyama, Y; Mikami, M; Morisawa, Y; Negoro, S; Takikawa, H; Tanaka, A; Uegaki, S; Yamamoto, T, 2007)
"To determine the factors underlying the apparent reduction in binding ability of thyroxine-binding globulin in hepatocellular carcinoma, hormone-binding characteristics were further examined in patients with this disease and in control subjects."7.68Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease. ( Fagan, EA; Hutchinson, WL; Johnson, PJ; White, YS; Williams, R, 1991)
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats."7.67Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986)
"The liver dysfunction was associated with hypothyroidism that resolved with thyroid hormone treatment."5.38Hypothyroidism and levothyroxine-responsive liver dysfunction in a patient with ring chromosome 18 syndrome. ( Hara, T; Ihara, K; Ishimura, M; Ohga, S; Ohkubo, K, 2012)
"In patients with primary hypothyroidism, IGF-I concentrations increased from 101 +/- 57 to 158 +/- 60 microg/l (P < 0."5.33Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarism. ( Brändle, M; Krayenbühl, PA; Schmid, C; Wiesli, P; Zapf, J; Zwimpfer, C, 2006)
"ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels."5.27Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983)
"We report a patient with primary hypothyroidism, who developed hepatocellular injury due to levothyroxine, synthetic thyroxine."3.74Liver injury induced by levothyroxine in a patient with primary hypothyroidism. ( Aiso, M; Fukusato, T; Hojo, M; Ishii, T; Kawakami, T; Kawasaki, T; Kuyama, Y; Mikami, M; Morisawa, Y; Negoro, S; Takikawa, H; Tanaka, A; Uegaki, S; Yamamoto, T, 2007)
" Of the drugs investigated, levothyroxine use was associated with an increased risk of hypoglycemia in patients with liver impairment (adjusted odds ratio; non-use with normal liver (reference), non-use with liver impairment 0."3.74Risk of hypoglycemia associated with thyroid agents is increased in patients with liver impairment. ( Iihara, N; Kurosaki, Y; Morita, S; Takada, M, 2008)
" The aim of the present study was to investigate the contribution of iodothyronines to liver oxidative stress in the functional hyperthyroidism elicited by cold, using as models cold-exposed and 3,5,3'-triiodothyronine (T3)- or thyroxine (T4)-treated rats."3.73Differential effects of experimental and cold-induced hyperthyroidism on factors inducing rat liver oxidative damage. ( Ayala, V; Caldarone, G; De Rosa, R; Di Meo, S; Pamplona, R; Venditti, P, 2006)
" We have seen transient increases in total thyroxine (TT4), free thyroxine index (FTI), free thyroxine (FT4), and total triiodothyronine (TT3) in 12 women and 3 men with subacute thyroiditis and 2 women with painless (silent) postpartum thyroiditis."3.68[Elevated thyroid hormone levels in the absence of hyperactivity]. ( Feigl, D; Nakash, I; Tuval, M, 1992)
"To determine the factors underlying the apparent reduction in binding ability of thyroxine-binding globulin in hepatocellular carcinoma, hormone-binding characteristics were further examined in patients with this disease and in control subjects."3.68Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease. ( Fagan, EA; Hutchinson, WL; Johnson, PJ; White, YS; Williams, R, 1991)
" Here, we report a case of acute intermittent porphyria with attacks of abdominal pain, an elevated serum thyroxine level, and hypercholesterolemia with an increased level of high-density lipoprotein-cholesterol concentration."3.67Abnormal thyroid function and hypercholesterolemia in a case of acute intermittent porphyria. ( Hsiao, KJ; Lee, FY; Lee, SD; Shiue, JW; Tsai, YT; Wu, SJ, 1989)
"In order to clarify an alteration in thyroid functions in patients with chronic liver diseases, serum total and free thyroxine (T4, FT4), total and free triiodothyronine (T3, FT3), total reverse T3 (rT3), thyrotropin (TSH), thyroxine-binding globulin (TBG) concentrations, and T3 uptake (T3U) were measured by radioimmunoassays in 53 patients with chronic hepatitis (CH), 24 patients with compensated liver cirrhosis (LC), 17 patients with hepatocellular carcinoma associated with LC (HCC), and 40 normal subjects."3.67Thyroid functions in patients with various chronic liver diseases. ( Higashi, K; Sato, T; Shimada, T; Umeda, T, 1988)
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats."3.67Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986)
"To further evaluate thyroid function in patients with liver disease, we have measured total and free T3 and T4, thyroxine binding globulin, basal and thyrotropin releasing hormone-stimulated thyrotropin and thyroglobulin antibodies in 33 patients with liver cirrhosis, in 22 with chronic hepatitis and in 30 healthy controls."3.66Thyroid function tests in chronic liver disease: evidence for multiple abnormalities despite clinical euthyroidism. ( Borzio, F; Borzio, M; Caldara, R; Ferrari, C; Piepoli, V; Rampini, P, 1983)
"Levels of serum triiodothyronine (T3), reverse triiodothyronine (rT3), and thyroxine (T4) were determined in 29 patients with alcoholic cirrhosis, seven patients with acute hepatitis, and 14 control patients hospitalized for chronic disease."3.66Serum thyroid hormone levels in patients with liver disease. ( Chopra, IJ; Hepner, GW, 1979)
"A total of 100 cases of liver cirrhosis were enrolled in our study with a mean age of 53."1.72A Clinical Study of Cirrhosis with Special Reference to Thyroid Function. ( Kapur, KS; Sikarwar, SS; Usmani, MH, 2022)
"Hypothyroidism was subsequently diagnosed."1.62Acute Hepatopathy in a Dog Secondary to Hypothyroidism-Induced Atherosclerotic Infarction and Necrosis. ( Bolton, TA, 2021)
"The liver dysfunction was associated with hypothyroidism that resolved with thyroid hormone treatment."1.38Hypothyroidism and levothyroxine-responsive liver dysfunction in a patient with ring chromosome 18 syndrome. ( Hara, T; Ihara, K; Ishimura, M; Ohga, S; Ohkubo, K, 2012)
"In patients with primary hypothyroidism, IGF-I concentrations increased from 101 +/- 57 to 158 +/- 60 microg/l (P < 0."1.33Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarism. ( Brändle, M; Krayenbühl, PA; Schmid, C; Wiesli, P; Zapf, J; Zwimpfer, C, 2006)
"Hexachlorobenzene (HCB) is a highly lipophilic organochlorine compound of widespread environmental occurrence, that accumulates in the biological system."1.31Association between serum concentrations of hexachlorobenzene and polychlorobiphenyls with thyroid hormone and liver enzymes in a sample of the general population. ( Grimalt, J; Herrero, C; Sala, M; Sunyer, J; To-Figueras, J, 2001)
"Hypothyroidism was diagnosed."1.31[High levels of carcinoembryonic antigen in a woman with hypothyroidism]. ( Beijer, C; Jonkers, GJ; van Mil, AH, 2001)
"ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels."1.27Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983)
"Twenty-seven patients with primary hypothyroidism were studied to evaluate the relationship between hepatic function and thyroid hormone deficiency in this disorder."1.27Hepatic dysfunction in primary hypothyroidism. ( Naomi, S; Sato, T; Shimada, T; Tajiri, J; Umeda, T, 1984)
"Similarly, the presence or absence of hepatic encephalopathy determined, and/or reflected, at least in part, the type of response observed."1.27Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease. ( Gavaler, JS; Sanghvi, A; Schade, RR; Tarter, R; Van Thiel, DH, 1986)

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199064 (68.82)18.7374
1990's8 (8.60)18.2507
2000's12 (12.90)29.6817
2010's5 (5.38)24.3611
2020's4 (4.30)2.80

Authors

AuthorsStudies
Sikarwar, SS1
Usmani, MH1
Kapur, KS1
Singh, B1
Hooda, N1
Baidya, S1
Bolton, TA1
Bebars, GM1
Sayed, MA1
Hamdy, L1
Abdel Aziz, RA1
Muchtar, E1
Dean, DS1
Dispenzieri, A1
Dingli, D1
Buadi, FK1
Lacy, MQ1
Hayman, SR1
Kapoor, P1
Leung, N1
Russell, S1
Lust, JA1
Lin, Y1
Warsame, R1
Gonsalves, W1
Kourelis, TV1
Go, RS1
Chakraborty, R1
Zeldenrust, S1
Kyle, RA1
Rajkumar, SV1
Kumar, SK1
Gertz, MA1
Duong, N1
Lee, A1
Lewis, J1
Yu, H1
Zhang, W1
Shen, C1
Zhang, H2
Zhang, Y1
Zou, D1
Gong, X1
Kalashnikova, SA1
Goryachev, AN1
Novochadov, VV1
Shchyogolev, AI1
Moustafa, AH1
Ali, EM1
Mohamed, TM1
Abdou, HI1
GUYE, P1
RUTISHAUSER, E1
Braslavsky, D1
Keselman, A1
Galoppo, M1
Lezama, C1
Chiesa, A1
Galoppo, C1
Bergadá, I1
Ohkubo, K1
Ihara, K1
Ohga, S1
Ishimura, M1
Hara, T1
BERTOLANI, F1
BENATTI, G1
ATERMAN, K1
FOLDES, J1
LENGYEL, Z1
VANNOTTI, A1
BERAUD, T1
INADA, M2
DATE, T1
PORTIOLI, RI1
SALVI, G1
BONGIORNI, G1
MORSCIA, C1
Iihara, N2
Kurokohchi, K1
Tsukamoto, T1
Masaki, T1
Kuriyama, S1
Ohnishi, H1
Taminato, T1
Morita, S3
Ieiri, T1
Venditti, P1
Pamplona, R1
Ayala, V1
De Rosa, R1
Caldarone, G1
Di Meo, S1
Schmid, C1
Zwimpfer, C1
Brändle, M1
Krayenbühl, PA1
Zapf, J1
Wiesli, P1
Kawakami, T1
Tanaka, A1
Negoro, S1
Morisawa, Y1
Mikami, M1
Hojo, M1
Yamamoto, T1
Uegaki, S1
Aiso, M1
Kawasaki, T1
Ishii, T1
Kuyama, Y1
Fukusato, T1
Takikawa, H1
Hull, K1
Horenstein, R1
Naglieri, R1
Munir, K1
Ghany, M1
Celi, FS1
Kurosaki, Y1
Takada, M1
Melmed, S1
Geola, FL1
Reed, AW2
Pekary, AE1
Park, J1
Hershman, JM2
Brent, GA1
Sastre, A1
Lieberman, J1
Hehrmann, R1
Heinen, E1
Pingleton, SK1
Borzio, M1
Caldara, R1
Borzio, F1
Piepoli, V1
Rampini, P1
Ferrari, C1
Yamaba, Y1
Kuroda, H1
Banba, N1
Kasai, K1
Shimoda, S1
Shinohara, K1
Matsuda, H1
Mitsuma, T1
Chaya, M1
Kaptein, EM2
Feinstein, EI1
Nicoloff, JT2
Massry, SG1
Sheridan, P1
Tajiri, J1
Shimada, T2
Naomi, S1
Umeda, T2
Sato, T2
Robinson, WJ1
Grieb, DA1
Kondo, S1
Masuda, Y1
Masuoka, T1
Okawa, H1
Mardell, RJ1
Gamlen, TR1
Midgley, JE1
Wilkins, TA1
Vierling, JM1
Kurihara, S1
Koike, S1
Kusakabe, K1
Demura, R1
Demura, H1
Akiba, H1
Giudici Cipriani, A1
Marenco, G1
Artom, A1
Menardo, G1
Colombo, P1
Rembado, R1
Barbetti, V1
Peterson, ME1
Djordjević, PB1
Stajić, MS1
Jovanović, P1
Sinadinović, J1
Patten, RL1
Hewitt, D1
Waldman, GT1
Jones, G1
Little, JA1
Kraft, W1
Dietl, A1
Seppel, T1
Becker, A1
Lippert, F1
Schlaghecke, R1
Davies, PH1
Black, EG1
Sheppard, MC1
Franklyn, JA1
Pinna, G1
Meinhold, H1
Hiedra, L1
Thoma, R1
Hoell, T1
Gräf, KJ1
Stoltenburg-Didinger, G1
Eravci, M1
Prengel, H1
Brödel, O1
Finke, R1
Baumgartner, A1
Wegdam, JA1
Kooistra, HM1
Kingma, BJ1
Rojer, RA1
Sala, M1
Sunyer, J1
Herrero, C1
To-Figueras, J1
Grimalt, J1
van Mil, AH1
Beijer, C1
Jonkers, GJ1
Del Monte, U1
Kodding, R1
Janzen, J1
Schmidt, E1
Hesch, RD2
Schussler, GC1
Schaffner, F1
Korn, F1
Green, JR2
Chopra, IJ2
Teco, GN1
Nguyen, AH1
Solomon, DH1
Gavin, LA1
Rosenthal, M1
Cavalieri, RR1
Biederman, EB1
Levey, GS1
Hepner, GW1
Pottkämper, G1
Gatz, J1
Schwinn, G1
Köbberling, J1
Snitcher, EJ1
Mowat, NA1
Rees, LH1
Ekins, RP1
Feigl, D1
Tuval, M1
Nakash, I1
Hutchinson, WL1
White, YS1
Fagan, EA1
Johnson, PJ1
Williams, R1
Hashimoto, T1
Kawai, K1
Nishibu, M1
Fujita, S1
Horita, H1
Shiue, JW1
Lee, FY1
Hsiao, KJ1
Tsai, YT1
Lee, SD1
Wu, SJ1
Kakezono, F1
Yamashita, S1
Yokoyama, N1
Kubo, I1
Ohtakara, S1
Okamoto, S1
Morimoto, I1
Ikari, N1
Izumi, M1
Van Thiel, DH2
Tarter, R2
Gavaler, JS3
Schade, RR2
Sanghvi, A2
Bauer, AG1
Wilson, JH1
Lamberts, SW1
Docter, R1
Hennemann, G1
Visser, TJ1
Higashi, K1
Mehta, MN1
Patel, MC1
Joseph, LJ1
Velumani, A1
Desai, KB1
Kanz, MF1
Whitehead, RF1
Ferguson, AE1
Moslen, MT1
Gerloff, BJ1
Herdt, TH1
Wells, WW1
Nachreiner, RF1
Emery, RS1
Zaloga, GP1
O'Brian, JT1
Doran, GR1
Chaudry, L1
Brubakk, AO1
Garrard, MP1
Wallace, RB1
Pomrehn, P1
Heiss, G1
Chambless, LE1
Johnson, N1
Patten, R1
Lippel, K1
Rifkind, BM1
Rozman, K1
Gorski, JR1
Rozman, P1
Parkinson, A1
Brase, A1
Ino, S1
Carter, JN1
Eastman, CJ1
Corcoran, JM1
Lazarus, L1
Ruge, W1
Krüskemper, HL3
Gillich, KH1
Zielske, F1
Morgner, KD2
Barzilai, DC1
Soloway, RD1
Summerskill, WH1
Schoenfield, LJ1
Mosin, VI1
Andreoli, M1
De Luca, F1
Negri, M1
Cramarossa, L1
Oppenheimer, JH1
Bernstein, G1
Hasen, J1
Seifert, E1
Abe, K1
Yamazaki, H1
Mazarean, HH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005128]0 participants Observational1972-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for thyroxine and Liver Dysfunction

ArticleYear
Liver dysfunction induced by Levothyroxine Sodium Tablets (Euthyrox®) in a hypothyroid patient with Hashimoto's thyroiditis: case report and literature review.
    Endocrine journal, 2019, Sep-28, Volume: 66, Issue:9

    Topics: Chemical and Drug Induced Liver Injury; Female; Hashimoto Disease; Hormone Replacement Therapy; Huma

2019
[Thyroxine binding globulin (TBG), triiodothyronine uptake (T3U), thyroxine binding capacity (TBC)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Biomarkers; Diabetic Ketoacidosis; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Liver Disea

2005
Complications of acute respiratory failure.
    The Medical clinics of North America, 1983, Volume: 67, Issue:3

    Topics: Acute Disease; Barotrauma; Cardiovascular Diseases; Gastrointestinal Diseases; Hematologic Diseases;

1983
Copper metabolism in primary biliary cirrhosis.
    Seminars in liver disease, 1981, Volume: 1, Issue:4

    Topics: Adrenal Cortex Hormones; Bile; Ceruloplasmin; Copper; Diet; Estrogens; Homeostasis; Humans; Intestin

1981
Euthyroid sick syndrome.
    American family physician, 1985, Volume: 31, Issue:2

    Topics: Aging; Diabetes Complications; Diagnosis, Differential; Diagnostic Errors; Energy Intake; Humans; Hy

1985
[Triosorb test: interpretation of the test results].
    Nihon rinsho. Japanese journal of clinical medicine, 1969

    Topics: Androgens; Female; Humans; Hyperthyroidism; Infant, Newborn; Iodine Radioisotopes; Liver Diseases; M

1969
[Thyroxine binding protein, free thyroxine and triiodothyronine--interpretation of the test results].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Child; Diabetes Mellitus; Female; Humans; Infectio

1973
[Thyroid gland and the liver].
    Klinicheskaia meditsina, 1973, Volume: 51, Issue:10

    Topics: Animals; Autopsy; Biopsy; Carbohydrate Metabolism; Female; Hepatitis; Humans; Hyperthyroidism; Liver

1973
[Physiopathology of plasmatic transport of thyroid hormones].
    Recenti progressi in medicina, 1969, Volume: 46, Issue:6

    Topics: Adrenal Gland Diseases; Blood Protein Electrophoresis; Humans; Hyperthyroidism; Hypothyroidism; Iodi

1969

Trials

1 trial available for thyroxine and Liver Dysfunction

ArticleYear
Circulating thyroxine in chronic active liver disease.
    Israel journal of medical sciences, 1974, Volume: 10, Issue:11

    Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Drug Therapy, Combination; Female; Humans; L

1974

Other Studies

83 other studies available for thyroxine and Liver Dysfunction

ArticleYear
A Clinical Study of Cirrhosis with Special Reference to Thyroid Function.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Aged; Cross-Sectional Studies; Humans; Liver Cirrhosis; Liver Diseases; Middle Aged; Thyroid

2022
Chronic Liver Disease Secondary to Chronic Budd Chiari Causing Osteomalacia Leading to Pathological Fractures.
    The Journal of the Association of Physicians of India, 2023, Volume: 71, Issue:1

    Topics: Adult; Bone Diseases, Metabolic; Calcium; End Stage Liver Disease; Female; Fractures, Multiple; Frac

2023
Acute Hepatopathy in a Dog Secondary to Hypothyroidism-Induced Atherosclerotic Infarction and Necrosis.
    Journal of the American Animal Hospital Association, 2021, Jan-01, Volume: 57, Issue:1

    Topics: Animals; Atherosclerosis; Dog Diseases; Dogs; Hepatic Infarction; Hypothyroidism; Liver Diseases; Ma

2021
Effect of acute and chronic liver diseases on the thyroid function in children.
    BMC pediatrics, 2021, 08-25, Volume: 21, Issue:1

    Topics: Humans; Liver Diseases; Liver Function Tests; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Th

2021
Prevalence and predictors of thyroid functional abnormalities in newly diagnosed AL amyloidosis.
    Journal of internal medicine, 2017, Volume: 281, Issue:6

    Topics: Aged; Amyloidosis; Antibodies; Comorbidity; Female; Hormone Replacement Therapy; Humans; Hypothyroid

2017
Case of acute mixed liver injury due to hypothyroidism.
    BMJ case reports, 2018, Jan-23, Volume: 2018

    Topics: Acute Disease; Aged; Female; Hashimoto Disease; Humans; Hypothyroidism; Liver Diseases; Retreatment;

2018
Thyroid modulation of TNF-dependent apoptosis and formation of chronic liver disease in endogenous intoxication in rats.
    Bulletin of experimental biology and medicine, 2009, Volume: 147, Issue:2

    Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Female;

2009
Oxidative stress and thyroid hormones in patients with liver diseases.
    European journal of internal medicine, 2009, Volume: 20, Issue:7

    Topics: Adult; Alanine Transaminase; Antioxidants; Apolipoprotein A-I; Aspartate Aminotransferases; Biomarke

2009
Anatomical and histological lesions of the liver in experimental thyroxine intoxication and in hyperthyroidism.
    Annales d'anatomie pathologique, 1947, Volume: 17, Issue:1

    Topics: Humans; Hyperthyroidism; Liver Diseases; Thyroid Gland; Thyroxine

1947
Neonatal cholestasis in congenital pituitary hormone deficiency and isolated hypocortisolism: characterization of liver dysfunction and follow-up.
    Arquivos brasileiros de endocrinologia e metabologia, 2011, Volume: 55, Issue:8

    Topics: Adrenal Insufficiency; Age of Onset; Cholestasis; Female; Follow-Up Studies; Hormone Replacement The

2011
Hypothyroidism and levothyroxine-responsive liver dysfunction in a patient with ring chromosome 18 syndrome.
    Thyroid : official journal of the American Thyroid Association, 2012, Volume: 22, Issue:10

    Topics: Child; Child, Preschool; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 18; Hep

2012
[Behavior of experimental dietary siderosis after adrenalectomy and during administration of desoxycorticosterone, ACTH and thyroxin].
    Bollettino della Societa italiana di biologia sperimentale, 1954, Volume: 30, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Desoxycorticosterone; Diet; Humans; Live

1954
The thyroid-adrenal relationship: the effect of cortisone and of thyroid hormone on hepatic necrosis of dietary origin in the rat.
    Endocrinology, 1957, Volume: 60, Issue:6

    Topics: Animals; Cortisone; Deficiency Diseases; Liver Diseases; Rats; Thyroid Gland; Thyroid Hormones; Thyr

1957
[Thyroxin-loading studies in liver, kidney and thyroid diseases].
    Orvosi hetilap, 1958, Dec-28, Volume: 99, Issue:52

    Topics: Disease; Humans; Kidney; Kidney Diseases; Liver Diseases; Thyroid Diseases; Thyroid Gland; Thyroxine

1958
Functional relationships between the liver, the thyroxine-binding protein of serum, and the thyroid.
    The Journal of clinical endocrinology and metabolism, 1959, Volume: 19, Issue:4

    Topics: Humans; Liver; Liver Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine; Thyroxine-Binding P

1959
[CLINICAL STUDIES ON THE METABOLISM OF THYROID HORMONES. L. STUDIES ON THE METABOLISM OF I-131-LABELLED 1-THYROXINE AND AGE DIFFERENCES IN NORMAL SUJECTS, IN PATIENTS WITH UNTREATED THYROID DISORDERS, AND IN PATIENTS WITH LIVER DISORDERS].
    Nihon Naibunpi Gakkai zasshi, 1963, Aug-20, Volume: 39

    Topics: Aging; Iodine; Iodine Isotopes; Liver Diseases; Metabolism; Thyroid Diseases; Thyroid Hormones; Thyr

1963
[EXPERIMENTAL AND CLINICAL STUDIES ON THE INFLUENCE OF BETA-GLUCURONIDASE INHIBITOR ON THE LIVING BODY].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, Jul-10, Volume: 53

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Biomedical Research; Diabetes Mellitus; Glucuronates; Glu

1964
[METABOLISM OF I-131 LABELLED L-AND D-THYROXINE IN THE LIVER PATIENT].
    Giornale di clinica medica, 1964, Volume: 45

    Topics: Dextrothyroxine; Humans; Iodine; Liver Diseases; Metabolism; Radioisotopes; Thyroxine

1964
Hypoglycaemia in patients with liver diseases administered levothyroxine.
    Journal of clinical pharmacy and therapeutics, 2003, Volume: 28, Issue:5

    Topics: Aged; Cross-Sectional Studies; Female; Humans; Hypoglycemia; Japan; Liver Diseases; Male; Middle Age

2003
Differential effects of experimental and cold-induced hyperthyroidism on factors inducing rat liver oxidative damage.
    The Journal of experimental biology, 2006, Volume: 209, Issue:Pt 5

    Topics: Animals; Antioxidants; Cold Temperature; Electron Transport Complex IV; Glucose-6-Phosphatase; Hydro

2006
Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarism.
    Clinical endocrinology, 2006, Volume: 65, Issue:6

    Topics: Acromegaly; Adult; Autoimmune Diseases; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Female;

2006
Liver injury induced by levothyroxine in a patient with primary hypothyroidism.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:14

    Topics: Chemical and Drug Induced Liver Injury; Humans; Hypothyroidism; Liver Diseases; Male; Middle Aged; T

2007
Two cases of thyroid storm-associated cholestatic jaundice.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2007, Volume: 13, Issue:5

    Topics: Adult; Alanine Transaminase; Antithyroid Agents; Bilirubin; Dexamethasone; Female; Glucocorticoids;

2007
Risk of hypoglycemia associated with thyroid agents is increased in patients with liver impairment.
    International journal of clinical pharmacology and therapeutics, 2008, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Case-Control Studies; Databases, Factual; Female; Hos

2008
A comparison of methods for assessing thyroid function in nonthyroidal illness.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:2

    Topics: Alpha-Globulins; Chronic Disease; Female; Humans; Hyperthyroidism; Hypothyroidism; Kidney Failure, C

1982
Serum angiotensin-converting enzyme in severe nonthyroidal illnesses associated with low serum thyroxine concentration.
    Annals of internal medicine, 1984, Volume: 100, Issue:5

    Topics: Critical Care; Dopamine; Female; Humans; Liver Diseases; Liver Diseases, Alcoholic; Male; Peptidyl-D

1984
[Procedures and problems in the diagnosis of hypothyroid conditions in adults].
    Der Internist, 1983, Volume: 24, Issue:8

    Topics: Adult; Age Factors; Aged; Autoantibodies; Diagnosis, Differential; Female; Humans; Hypothyroidism; K

1983
Thyroid function tests in chronic liver disease: evidence for multiple abnormalities despite clinical euthyroidism.
    Gut, 1983, Volume: 24, Issue:7

    Topics: Adult; Aged; Antibodies; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases

1983
[Changes of serum 3,5,3'-triiodothyronine (T3), thyroxine (T4), 3,3',5'-triiodothyronine (rT3) levels in patients with liver diseases. One marker for hepatic microsomal function].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1984, Volume: 81, Issue:5

    Topics: Adult; Aged; Female; Humans; Liver Diseases; Male; Microsomes, Liver; Middle Aged; Thyroxine; Triiod

1984
[Fundamental and clinical evaluation of a magnetic FT4 kit].
    Radioisotopes, 1984, Volume: 33, Issue:11

    Topics: Evaluation Studies as Topic; Female; Humans; Liver Diseases; Magnetics; Pregnancy; Radioimmunoassay;

1984
[The measurement of serum thyroxine--the evaluation of a magnetic FT4 radioimmunoassay kit].
    Radioisotopes, 1984, Volume: 33, Issue:11

    Topics: Evaluation Studies as Topic; Female; Humans; Liver Diseases; Magnetics; Pregnancy; Radioimmunoassay;

1984
Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis.
    Kidney international. Supplement, 1983, Volume: 16

    Topics: Adult; Aged; Body Weight; Chronic Disease; Female; Humans; Infections; Kidney Failure, Chronic; Kine

1983
Thyroid hormones and the liver.
    Clinics in gastroenterology, 1983, Volume: 12, Issue:3

    Topics: Humans; Hypothalamus; Liver; Liver Diseases; Pituitary Gland; Thyroid Diseases; Thyroid Gland; Thyro

1983
Hepatic dysfunction in primary hypothyroidism.
    Endocrinologia japonica, 1984, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Cholesterol; Female; Humans; Hypercholesterole

1984
Peripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in the low thyroxine state of acute nonthyroidal illnesses. A noncompartmental analysis.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:3

    Topics: Acute Disease; Adult; Aged; Binding Sites; Female; Humans; Infections; Kinetics; Liver Diseases; Mal

1982
[Thyroid hormones in the serum (author's transl)].
    Rinsho byori. The Japanese journal of clinical pathology, 1982, Volume: 30, Issue:2

    Topics: Female; Humans; Liver Diseases; Pregnancy; Serum Globulins; Thyroid Diseases; Thyroid Hormones; Thyr

1982
[Normal range of thyroxine binding globulin (TBG)--relationship to aging chronological change in TBG (author's transl)].
    Radioisotopes, 1982, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Liver Diseases; Male;

1982
Free-thyroxin concentration as affected by major illness.
    Clinical chemistry, 1983, Volume: 29, Issue:9

    Topics: Adult; Aged; Biliary Tract Diseases; Diabetes Mellitus; Diagnostic Errors; Female; Humans; Liver Dis

1983
[Studies on the measurement of serum free thyroxine with Amerlex Free T4 RIA Kit].
    Kaku igaku. The Japanese journal of nuclear medicine, 1982, Volume: 19, Issue:3

    Topics: Female; Humans; Kidney Failure, Chronic; Liver Diseases; Male; Pregnancy; Radioimmunoassay; Reagent

1982
[The importance of thyroid hormone determination in the course of acute and chronic liver diseases].
    Minerva medica, 1981, Oct-20, Volume: 72, Issue:40

    Topics: Acute Disease; Adolescent; Adult; Aged; Ascites; Chronic Disease; Female; Hepatitis, Viral, Human; H

1981
Propylthiouracil in the treatment of feline hyperthyroidism.
    Journal of the American Veterinary Medical Association, 1981, Sep-01, Volume: 179, Issue:5

    Topics: Administration, Oral; Animals; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Hyperthyr

1981
[Levels of the thyroid hormones, triiodothyronine and tetraiodothyronine, in the blood in liver diseases].
    Srpski arhiv za celokupno lekarstvo, 1981, Volume: 109, Issue:7

    Topics: Humans; Liver Diseases; Liver Neoplasms; Thyroxine; Triiodothyronine

1981
Associations of plasma high-density lipoprotein cholesterol with clinical chemistry data.
    Circulation, 1980, Volume: 62, Issue:4 Pt 2

    Topics: Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Chemical P

1980
[Total thyroxine (T4) and free thyroxine (FT4) in hypothyroidism and nonthyroid diseases of dogs].
    Tierarztliche Praxis, 1994, Volume: 22, Issue:5

    Topics: Alopecia; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; Dogs;

1994
Serum sex hormone-binding globulin and osteocalcin in systemic nonthyroidal illness associated with low thyroid hormone concentrations.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Communicable Diseases; Female;

1996
Relation between serum interleukin-6 and thyroid hormone concentrations in 270 hospital in-patients with non-thyroidal illness.
    Clinical endocrinology, 1996, Volume: 44, Issue:2

    Topics: Euthyroid Sick Syndromes; Heart Diseases; Humans; Interleukin-6; Kidney Diseases; Liver Diseases; Th

1996
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5

    Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma;

1997
[Ascites due to hypothyroidism].
    Nederlands tijdschrift voor geneeskunde, 1997, Sep-06, Volume: 141, Issue:36

    Topics: Aged; Ascites; Humans; Hypothyroidism; Liver Diseases; Liver Function Tests; Male; Thyroid Function

1997
Association between serum concentrations of hexachlorobenzene and polychlorobiphenyls with thyroid hormone and liver enzymes in a sample of the general population.
    Occupational and environmental medicine, 2001, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Biomarkers; Chemical and Drug Induced Liver Injury; E

2001
[High levels of carcinoembryonic antigen in a woman with hypothyroidism].
    Nederlands tijdschrift voor geneeskunde, 2001, Jun-02, Volume: 145, Issue:22

    Topics: Carcinoembryonic Antigen; Diagnosis, Differential; Female; Hormone Replacement Therapy; Humans; Hypo

2001
Thyroid hormones, acute iron overload and the pathogenesis of cloudy swelling.
    Redox report : communications in free radical research, 2001, Volume: 6, Issue:2

    Topics: 2,4-Dinitrophenol; Acute Disease; Animals; Bacterial Toxins; Cell Nucleus; Cell Size; Edema; Guinea

2001
Letter: Reverse triiodothyronine in liver disease.
    Lancet (London, England), 1976, Aug-07, Volume: 2, Issue:7980

    Topics: Humans; Liver Diseases; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1976
Increased serum thyroid hormone binding and decreased free hormone in chronic active liver disease.
    The New England journal of medicine, 1978, Sep-07, Volume: 299, Issue:10

    Topics: Autoantibodies; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Liver

1978
Thyroid function in chronic liver disease.
    Zeitschrift fur Gastroenterologie, 1979, Volume: 17, Issue:7

    Topics: Humans; Liver Diseases; Thyroid Gland; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine; T

1979
In search of an inhibitor of thyroid hormone binding to serum proteins in nonthyroid illnesses.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:1

    Topics: Antigen-Antibody Complex; Blood Proteins; Chemical Precipitation; Hot Temperature; Humans; Immunoglo

1979
The diagnostic dilemma of isolated hyperthyroxinemia in acute illness.
    JAMA, 1979, Jul-20, Volume: 242, Issue:3

    Topics: Acute Disease; Aged; Asthma; Carcinoma, Bronchogenic; Female; Heart Diseases; Humans; Infections; Li

1979
Hyperthyroidism or "sick euthyroid syndrome". A diagnostic dilemma.
    The Journal of the Florida Medical Association, 1979, Volume: 66, Issue:7

    Topics: Diagnosis, Differential; Female; Humans; Hyperthyroidism; Liver Diseases; Middle Aged; Thyroid Disea

1979
Serum thyroid hormone levels in patients with liver disease.
    Archives of internal medicine, 1979, Volume: 139, Issue:10

    Topics: Adult; Aged; Breath Tests; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Middle Age

1979
[Changes in thyroxine-binding capacity in liver diseases].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1

    Topics: Cholestasis; Hepatitis; Jaundice, Chronic Idiopathic; Liver Cirrhosis; Liver Diseases; Thyroxine; Th

1976
Proceedings: Anomalous TSH secretion in liver disease; further evidence of hypothalamic-pituitary dysfunction.
    Gut, 1976, Volume: 17, Issue:5

    Topics: Humans; Liver Diseases; Thyrotropin; Thyroxine; Triiodothyronine

1976
[Elevated thyroid hormone levels in the absence of hyperactivity].
    Harefuah, 1992, Mar-01, Volume: 122, Issue:5

    Topics: Contraceptive Agents; Diagnosis, Differential; Female; Humans; Hyperthyroidism; Liver Diseases; Male

1992
Impaired binding properties of thyroxine-binding globulin in hepatocellular carcinoma and chronic liver disease.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:1

    Topics: Adult; Carcinoma, Hepatocellular; Chronic Disease; Cytosol; Humans; Liver Diseases; Liver Neoplasms;

1991
Clinical evaluation of accuracy in determining serum free thyroxine and free triiodothyronine in patients with non-thyroidal illness: immunoglobulin effect on T3/TBG ratio and T4/TBG ratio.
    Endocrinologia japonica, 1991, Volume: 38, Issue:6

    Topics: Albumins; Humans; Immunoassay; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Kidney Diseases

1991
Abnormal thyroid function and hypercholesterolemia in a case of acute intermittent porphyria.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1989, Volume: 88, Issue:7

    Topics: Acute Disease; Adult; Female; Humans; Hypercholesterolemia; Liver Diseases; Porphyrias; Thyroid Glan

1989
Stimulation of thyroid adenylate cyclase activity by sera from patients with non-thyroidal illness.
    Acta endocrinologica, 1986, Volume: 113, Issue:3

    Topics: Adenylyl Cyclases; Cell Line; Collagen Diseases; Culture Media; Cyclic AMP; Diabetes Mellitus, Type

1986
Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease.
    Journal of endocrinological investigation, 1986, Volume: 9, Issue:6

    Topics: Carcinoma, Hepatocellular; Growth Hormone; Hepatic Encephalopathy; Humans; Liver Diseases; Liver Neo

1986
Handling of iodothyronines by the liver and kidney in patients with chronic liver disease.
    Acta endocrinologica, 1987, Volume: 116, Issue:3

    Topics: Adult; Aged; Chronic Disease; Diiodothyronines; Female; Humans; Kidney; Liver; Liver Diseases; Male;

1987
Thyroid functions in patients with various chronic liver diseases.
    Endocrinologia japonica, 1988, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Thyroid

1988
Serum thyroid hormone levels in patients with liver damage: evidence of multiple abnormalities in presence of euthyroidism.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:11

    Topics: Humans; Liver Diseases; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiod

1988
Potentiation of 1,1-dichloroethylene hepatotoxicity: comparative effects of hyperthyroidism and fasting.
    Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1

    Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Blood Glucose; Body Temperature; Chemical an

1988
Inositol and hepatic lipidosis. II. Effect of inositol supplementation and time from parturition on serum insulin, thyroxine and triiodothyronine and their relationship to serum and liver lipids in dairy cows.
    Journal of animal science, 1986, Volume: 62, Issue:6

    Topics: Animals; Biopsy, Needle; Cattle; Cattle Diseases; Female; Inositol; Insulin; Lipid Metabolism; Lipid

1986
Pituitary and thyroid hormone levels before and after orthotopic hepatic transplantation and their responses to thyrotropin-releasing hormone.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:3

    Topics: Adult; Female; Growth Hormone; Humans; Liver Diseases; Liver Transplantation; Male; Middle Aged; Pit

1985
Hyperbaric liver dysfunction in saturation divers.
    Undersea biomedical research, 1985, Volume: 12, Issue:2

    Topics: Diving; Enzymes; Glycoproteins; Humans; Liver Diseases; Male; Serum Albumin; Thyroid Hormones; Thyro

1985
Alterations in clinical chemistry levels associated with the dyslipoproteinemias. The Lipid Research Clinics Program Prevalence Study.
    Circulation, 1986, Volume: 73, Issue:1 Pt 2

    Topics: Adult; Blood Glucose; Creatinine; Diabetes Mellitus; Dysgammaglobulinemia; Female; Humans; Hyperlipo

1986
Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria.
    Toxicology letters, 1986, Volume: 30, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes;

1986
[Improved thyroid function tests with combined in vitro testing].
    Medizinische Klinik, 1971, Apr-16, Volume: 66, Issue:16

    Topics: Adolescent; Adult; Contraceptives, Oral; False Negative Reactions; False Positive Reactions; Female;

1971
Effect of severe, chronic illness on thyroid function.
    Lancet (London, England), 1974, Oct-26, Volume: 2, Issue:7887

    Topics: Administration, Oral; Adult; Aged; Airway Obstruction; Chronic Disease; Female; Humans; Intensive Ca

1974
[Serum tyrosine determination as a thyroid function test].
    Deutsche medizinische Wochenschrift (1946), 1968, Dec-06, Volume: 93, Issue:49

    Topics: Alkaline Phosphatase; Diagnosis, Differential; Humans; Hyperthyroidism; Hypothyroidism; Kwashiorkor;

1968
[Protein-bound iodine and D-thyroxine turnover in liver diseases].
    Klinische Wochenschrift, 1969, Oct-15, Volume: 47, Issue:20

    Topics: Acute Disease; Blood Proteins; Cholestasis; Chronic Disease; Diabetes Complications; Diagnosis, Diff

1969
Estimation of rapidly exchangeable cellular thyroxine from the plasma disappearance curves of simultaneously administered thyroxine-131-I and albumin-125-I.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:5

    Topics: Heart Failure; Humans; Iodine Isotopes; Liver; Liver Diseases; Radioisotope Dilution Technique; Seru

1967
[D-thyroxine metabolism in hepatic insufficiency].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1969, Volume: 75

    Topics: Cholestasis; Humans; Liver Cirrhosis; Liver Diseases; Thyroxine

1969
[Measurement of free thyroxine in the blood].
    Rinsho byori. The Japanese journal of clinical pathology, 1968, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Female; Humans; Iodine Radioisotopes; Liver Diseases; Male; Methods; Middle Aged;

1968
The change of alanine-ketoglutaric transaminase activity on the effect of leucine in liver of rats treated with thyroxine.
    Die Naturwissenschaften, 1966, Volume: 53, Issue:2

    Topics: Alanine Transaminase; Animals; Ketoglutaric Acids; Leucine; Liver Diseases; Rats; Thyroxine

1966