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thyroxine and Leukopenia

thyroxine has been researched along with Leukopenia in 6 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).

Research Excerpts

ExcerptRelevanceReference
" The present studies were conducted in an attempt to assess the in vivo contribution of leukocytes and peripheral leukocytosis to the enhancement of L-thyroxine (T4) clearance seen during infection, and to evaluate further the possible roles of fever and of changes in the extracellular binding of T4."7.65Accelerated host metabolism of L-thyroxine during acute infection: role of the leukocyte and peripheral leukocytosis. ( DeRubertis, FR; Kosch, PC, 1975)
" The patient was subsequently treated with levothyroxine because of the occurrence of a iatrogenic hypothyroidism."3.70[Hematological changes in hyperthyroidism. A case report]. ( Bertola, G; Bocchia, M; Orlandini, B; Ribotto, P; Torchio, G, 1998)
" The present studies were conducted in an attempt to assess the in vivo contribution of leukocytes and peripheral leukocytosis to the enhancement of L-thyroxine (T4) clearance seen during infection, and to evaluate further the possible roles of fever and of changes in the extracellular binding of T4."3.65Accelerated host metabolism of L-thyroxine during acute infection: role of the leukocyte and peripheral leukocytosis. ( DeRubertis, FR; Kosch, PC, 1975)
" Possible adverse effects of this therapy include cardiovascular changes (shortening of systolic time intervals, increased frequency of atrial premature beats and, possibly, left ventricular hypertrophy) and bone changes (reduced bone density and bone mass), but the risk of these adverse effects can be minimised by carefully monitoring serum free thyroxine and free liothyronine (triiodothyronine) measurements and adjusting the dosage accordingly."2.39Adverse effects of thyroid hormone preparations and antithyroid drugs. ( Bartalena, L; Bogazzi, F; Martino, E, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ASCHKENASY, A1
Bartalena, L1
Bogazzi, F1
Martino, E1
Bertola, G1
Bocchia, M1
Ribotto, P1
Orlandini, B1
Torchio, G1
DeRubertis, FR1
Kosch, PC1
Kramlinger, KG1
Post, RM1
Lahat, N1
Sheinfeld, M1
Baron, E1
Glaser, B1

Reviews

1 review available for thyroxine and Leukopenia

ArticleYear
Adverse effects of thyroid hormone preparations and antithyroid drugs.
    Drug safety, 1996, Volume: 15, Issue:1

    Topics: Adult; Agranulocytosis; Antithyroid Agents; Bone and Bones; Carbimazole; Cardiovascular System; Chil

1996

Trials

1 trial available for thyroxine and Leukopenia

ArticleYear
Addition of lithium carbonate to carbamazepine: hematological and thyroid effects.
    The American journal of psychiatry, 1990, Volume: 147, Issue:5

    Topics: Adult; Blood Cell Count; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1990

Other Studies

4 other studies available for thyroxine and Leukopenia

ArticleYear
[Effect of testosterone, thyroxin and cortisone on the evolution of anemia and leukopenia of protein deficiency].
    Le Sang, 1954, Volume: 25, Issue:1

    Topics: Anemia; Cortisone; Leukocyte Count; Leukopenia; Protein Deficiency; Testosterone; Thyroxine

1954
[Hematological changes in hyperthyroidism. A case report].
    Recenti progressi in medicina, 1998, Volume: 89, Issue:4

    Topics: Anemia; Female; Follow-Up Studies; Graves Disease; Humans; Hypothyroidism; Iatrogenic Disease; Iodin

1998
Accelerated host metabolism of L-thyroxine during acute infection: role of the leukocyte and peripheral leukocytosis.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:4

    Topics: Acute Disease; Animals; Carbon; Encephalitis Virus, Venezuelan Equine; Fever; Infections; Iodine Rad

1975
L-Thyroxine-induced leukopenia in a patient with Hashimoto's disease: involvement of suppressor-cytotoxic T cells.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:5

    Topics: Female; Humans; Leukopenia; Middle Aged; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Thyroi

1985