thyroxine and Leukemia
thyroxine has been researched along with Leukemia in 18 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Children with cancer were also evaluated after antineoplasic treatment (CAT, n = 17)." | 1.38 | Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment. ( Brito, CX; Guerra, RN; Liberio, SA; Lima, MV; Mendonça, C; Mouchrek-Filho, JC; Nascimento, FR; Oliveira-Junior, JJ; Paim, DB; Pereira, AL, 2012) |
| "Another 16% had mild primary hypothyroidism (TSH, 5-15 mU/L)." | 1.30 | Diagnosis of hidden central hypothyroidism in survivors of childhood cancer. ( Broome, DC; Burghen, GA; Heideman, RL; Hudson, MM; Kun, LE; Li, H; Lustig, RH; Pitukcheewanont, P; Rose, SR, 1999) |
| "Patients with severe aplastic anemia (n = 6) were transplanted without total body irradiation (TBI) and they had no detectable alterations in thyroid function." | 1.29 | Thyroid function in children after allogeneic bone marrow transplantation. ( Bolme, P; Borgström, B, 1994) |
| "Patients with malignant lymphoma and acute myeloid leukemia showed a significant decrease in enzyme activity (p less than 0." | 1.27 | Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions. ( Saito, T, 1987) |
Research
Studies (18)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (61.11) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lee, YJ | 1 |
| Lee, HY | 1 |
| Ahn, MB | 1 |
| Kim, SK | 1 |
| Cho, WK | 1 |
| Lee, JW | 1 |
| Chung, NG | 1 |
| Cho, B | 1 |
| Suh, BK | 1 |
| Guerra, RN | 1 |
| Oliveira-Junior, JJ | 1 |
| Mouchrek-Filho, JC | 1 |
| Liberio, SA | 1 |
| Lima, MV | 1 |
| Paim, DB | 1 |
| Brito, CX | 1 |
| Mendonça, C | 1 |
| Nascimento, FR | 1 |
| Pereira, AL | 1 |
| SILBER, R | 1 |
| HUENNEKENS, FM | 1 |
| GABRIO, BW | 1 |
| van Santen, HM | 1 |
| Thonissen, NM | 1 |
| de Kraker, J | 1 |
| Vulsma, T | 1 |
| Kaledin, VI | 1 |
| Il'nitskaia, SI | 1 |
| Baginskaia, NV | 1 |
| Kholodar', AV | 1 |
| Obut, TA | 1 |
| Pekić, B | 2 |
| Popović, M | 1 |
| Pavelić, K | 2 |
| Gabrilovac, J | 1 |
| Bratic-Mikes, V | 1 |
| Boranic, M | 1 |
| Borgström, B | 1 |
| Bolme, P | 1 |
| Rose, SR | 1 |
| Lustig, RH | 1 |
| Pitukcheewanont, P | 1 |
| Broome, DC | 1 |
| Burghen, GA | 1 |
| Li, H | 1 |
| Hudson, MM | 1 |
| Kun, LE | 1 |
| Heideman, RL | 1 |
| Carter, JN | 1 |
| Corcoran, JM | 1 |
| Eastman, CJ | 1 |
| Lazarus, L | 1 |
| O'Halloran, M | 1 |
| Hershman, JM | 1 |
| Eriksen, E | 1 |
| Kaufman, N | 1 |
| Champlin, RE | 1 |
| Feyer, P | 1 |
| Titlbach, O | 1 |
| Hoffmann, FA | 1 |
| Kubel, M | 1 |
| Helbig, W | 1 |
| Kirkegaard, C | 1 |
| Hasselbalch, H | 1 |
| Faber, J | 1 |
| Poulsen, S | 1 |
| Bregengård, C | 1 |
| Hasselstrøm, K | 1 |
| Saito, T | 1 |
| Voorhess, ML | 1 |
| Brecher, ML | 1 |
| Glicksman, AS | 1 |
| Jones, B | 1 |
| Harris, M | 1 |
| Krischer, J | 1 |
| Boyett, J | 1 |
| Forman, E | 1 |
| Freeman, AI | 1 |
| Wehmann, RE | 1 |
| Gregerman, RI | 1 |
| Burns, WH | 1 |
| Saral, R | 1 |
| Santos, GW | 1 |
| Pochin, EE | 1 |
| Parfitt, AM | 1 |
| Dent, CE | 1 |
Reviews
1 review available for thyroxine and Leukemia
| Article | Year |
|---|---|
Radioiodine therapy of thyroid cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Biopsy; Bone Marrow Diseases; Carcinoma; Half-Life; Human | 1971 |
Other Studies
17 other studies available for thyroxine and Leukemia
| Article | Year |
|---|---|
Thyroid dysfunction in children with leukemia over the first year after hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; Humans; | 2018 |
Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.
Topics: Biomarkers; Blood Glucose; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Stu | 2012 |
STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. V. PYRIDINE NUCLEOTIDE TRANSHYDROGENASES.
Topics: Benzoates; Cadmium; Clinical Enzyme Tests; Enzyme Inhibitors; Humans; Leukemia; Leukemia, Lymphoid; | 1963 |
Changes in thyroid hormone state in children receiving chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 2005 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; F | 2005 |
[Changes in hormone concentrations in the blood of patients with malignant diseases of the blood].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Growth Hormone; Hodgkin Disease; Hormones; Humans; Hydroco | 1984 |
Hormonal changes in patients with haematological malignancies.
Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho | 1981 |
Thyroid function in children after allogeneic bone marrow transplantation.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Female; Humans; | 1994 |
Diagnosis of hidden central hypothyroidism in survivors of childhood cancer.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Head and Neck Neoplasms; Humans; Hypot | 1999 |
Serum T3 and T4 levels in sick children.
Topics: Adolescent; Burns; Child; Child, Preschool; Gastrointestinal Diseases; Humans; Infant; Infant, Newbo | 1976 |
Thyroid function tests in patients undergoing bone marrow transplantation.
Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Female; Humans; Leukemia; Lymphoma; Male; Thyr | 1990 |
Endocrine dysfunction after total body irradiation and bone marrow transplantation.
Topics: Adrenocorticotropic Hormone; Adult; Bone Marrow Transplantation; Endocrine System Diseases; Female; | 1989 |
Thyroid hormone metabolism in hypermetabolic patients with haematological disorders.
Topics: Adult; Aged; Aged, 80 and over; Female; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Midd | 1989 |
Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions.
Topics: Erythrocytes; Humans; Leukemia; Lung Neoplasms; Lymphoma; Superoxide Dismutase; Thyroid Diseases; Th | 1987 |
Hypothalamic-pituitary function of children with acute lymphocytic leukemia after three forms of central nervous system prophylaxis. A retrospective study.
Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Combined Modality Thera | 1986 |
Suppression of thyrotropin in the low-thyroxine state of severe nonthyroidal illness.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Dopamine; | 1985 |
Hyperthyroidism and hypercalcaemia.
Topics: Acromegaly; Acute Kidney Injury; Adult; Alkaline Phosphatase; Carcinoma, Papillary; Female; Gout; Hu | 1970 |