Page last updated: 2024-11-06

thyroxine and Leukemia

thyroxine has been researched along with Leukemia in 18 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Children with cancer were also evaluated after antineoplasic treatment (CAT, n = 17)."1.38Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment. ( Brito, CX; Guerra, RN; Liberio, SA; Lima, MV; Mendonça, C; Mouchrek-Filho, JC; Nascimento, FR; Oliveira-Junior, JJ; Paim, DB; Pereira, AL, 2012)
"Another 16% had mild primary hypothyroidism (TSH, 5-15 mU/L)."1.30Diagnosis of hidden central hypothyroidism in survivors of childhood cancer. ( Broome, DC; Burghen, GA; Heideman, RL; Hudson, MM; Kun, LE; Li, H; Lustig, RH; Pitukcheewanont, P; Rose, SR, 1999)
"Patients with severe aplastic anemia (n = 6) were transplanted without total body irradiation (TBI) and they had no detectable alterations in thyroid function."1.29Thyroid function in children after allogeneic bone marrow transplantation. ( Bolme, P; Borgström, B, 1994)
"Patients with malignant lymphoma and acute myeloid leukemia showed a significant decrease in enzyme activity (p less than 0."1.27Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions. ( Saito, T, 1987)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's3 (16.67)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, YJ1
Lee, HY1
Ahn, MB1
Kim, SK1
Cho, WK1
Lee, JW1
Chung, NG1
Cho, B1
Suh, BK1
Guerra, RN1
Oliveira-Junior, JJ1
Mouchrek-Filho, JC1
Liberio, SA1
Lima, MV1
Paim, DB1
Brito, CX1
Mendonça, C1
Nascimento, FR1
Pereira, AL1
SILBER, R1
HUENNEKENS, FM1
GABRIO, BW1
van Santen, HM1
Thonissen, NM1
de Kraker, J1
Vulsma, T1
Kaledin, VI1
Il'nitskaia, SI1
Baginskaia, NV1
Kholodar', AV1
Obut, TA1
Pekić, B2
Popović, M1
Pavelić, K2
Gabrilovac, J1
Bratic-Mikes, V1
Boranic, M1
Borgström, B1
Bolme, P1
Rose, SR1
Lustig, RH1
Pitukcheewanont, P1
Broome, DC1
Burghen, GA1
Li, H1
Hudson, MM1
Kun, LE1
Heideman, RL1
Carter, JN1
Corcoran, JM1
Eastman, CJ1
Lazarus, L1
O'Halloran, M1
Hershman, JM1
Eriksen, E1
Kaufman, N1
Champlin, RE1
Feyer, P1
Titlbach, O1
Hoffmann, FA1
Kubel, M1
Helbig, W1
Kirkegaard, C1
Hasselbalch, H1
Faber, J1
Poulsen, S1
Bregengård, C1
Hasselstrøm, K1
Saito, T1
Voorhess, ML1
Brecher, ML1
Glicksman, AS1
Jones, B1
Harris, M1
Krischer, J1
Boyett, J1
Forman, E1
Freeman, AI1
Wehmann, RE1
Gregerman, RI1
Burns, WH1
Saral, R1
Santos, GW1
Pochin, EE1
Parfitt, AM1
Dent, CE1

Reviews

1 review available for thyroxine and Leukemia

ArticleYear
Radioiodine therapy of thyroid cancer.
    Seminars in nuclear medicine, 1971, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Biopsy; Bone Marrow Diseases; Carcinoma; Half-Life; Human

1971

Other Studies

17 other studies available for thyroxine and Leukemia

ArticleYear
Thyroid dysfunction in children with leukemia over the first year after hematopoietic stem cell transplantation.
    Journal of pediatric endocrinology & metabolism : JPEM, 2018, Nov-27, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; Humans;

2018
Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012, Volume: 41, Issue:7

    Topics: Biomarkers; Blood Glucose; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Stu

2012
STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. V. PYRIDINE NUCLEOTIDE TRANSHYDROGENASES.
    The Journal of clinical investigation, 1963, Volume: 42

    Topics: Benzoates; Cadmium; Clinical Enzyme Tests; Enzyme Inhibitors; Humans; Leukemia; Leukemia, Lymphoid;

1963
Changes in thyroid hormone state in children receiving chemotherapy.
    Clinical endocrinology, 2005, Volume: 62, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool;

2005
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2005, Volume: 91, Issue:12

    Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; F

2005
[Changes in hormone concentrations in the blood of patients with malignant diseases of the blood].
    Srpski arhiv za celokupno lekarstvo, 1984, Volume: 112, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Growth Hormone; Hodgkin Disease; Hormones; Humans; Hydroco

1984
Hormonal changes in patients with haematological malignancies.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 35, Issue:6

    Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho

1981
Thyroid function in children after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 13, Issue:1

    Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Female; Humans;

1994
Diagnosis of hidden central hypothyroidism in survivors of childhood cancer.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:12

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Head and Neck Neoplasms; Humans; Hypot

1999
Serum T3 and T4 levels in sick children.
    Pediatrics, 1976, Volume: 58, Issue:5

    Topics: Adolescent; Burns; Child; Child, Preschool; Gastrointestinal Diseases; Humans; Infant; Infant, Newbo

1976
Thyroid function tests in patients undergoing bone marrow transplantation.
    Bone marrow transplantation, 1990, Volume: 6, Issue:1

    Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Female; Humans; Leukemia; Lymphoma; Male; Thyr

1990
Endocrine dysfunction after total body irradiation and bone marrow transplantation.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:3-4

    Topics: Adrenocorticotropic Hormone; Adult; Bone Marrow Transplantation; Endocrine System Diseases; Female;

1989
Thyroid hormone metabolism in hypermetabolic patients with haematological disorders.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Midd

1989
Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1987, Volume: 62, Issue:2

    Topics: Erythrocytes; Humans; Leukemia; Lung Neoplasms; Lymphoma; Superoxide Dismutase; Thyroid Diseases; Th

1987
Hypothalamic-pituitary function of children with acute lymphocytic leukemia after three forms of central nervous system prophylaxis. A retrospective study.
    Cancer, 1986, Apr-01, Volume: 57, Issue:7

    Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Combined Modality Thera

1986
Suppression of thyrotropin in the low-thyroxine state of severe nonthyroidal illness.
    The New England journal of medicine, 1985, Feb-28, Volume: 312, Issue:9

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Dopamine;

1985
Hyperthyroidism and hypercalcaemia.
    The Quarterly journal of medicine, 1970, Volume: 39, Issue:154

    Topics: Acromegaly; Acute Kidney Injury; Adult; Alkaline Phosphatase; Carcinoma, Papillary; Female; Gout; Hu

1970