thyroxine has been researched along with Learning Disabilities in 12 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The major purpose of this study was to investigate the effect of resveratrol (RES) on the spatial learning and memory ability in subclinical hypothyroidism (SCH) rat model and the potential mechanism." | 7.81 | Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. ( Chen, FH; Chu, CH; Ge, JF; Li, N; Qin, G; Qiu, GL; Wang, CY; Xu, YY; Zhang, Y, 2015) |
| "To describe intellectual, motor, and school-associated outcome in young adults with early treated congenital hypothyroidism (CH) and to study the association between long-term outcome and CH variables acting at different points in time during early development (CH severity and early L-thyroxine treatment levels [0-6 years])." | 7.72 | Congenital hypothyroidism: influence of disease severity and L-thyroxine treatment on intellectual, motor, and school-associated outcomes in young adults. ( Heyerdahl, S; Kase, BF; Oerbeck, B; Sundet, K, 2003) |
| "The observation of severe behavioral reactions or learning problems in three teenagers treated with L-thyroxine for juvenile acquired hypothyroidism prompted us to conduct a prospective study of achievement and behavioral characteristics of patients with newly diagnosed juvenile acquired hypothyroidism." | 7.68 | Psychologic and psychoeducational consequences of thyroxine therapy for juvenile acquired hypothyroidism. ( Bailey, JD; Daneman, D; Rovet, JF, 1993) |
| "The major purpose of this study was to investigate the effect of resveratrol (RES) on the spatial learning and memory ability in subclinical hypothyroidism (SCH) rat model and the potential mechanism." | 3.81 | Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. ( Chen, FH; Chu, CH; Ge, JF; Li, N; Qin, G; Qiu, GL; Wang, CY; Xu, YY; Zhang, Y, 2015) |
| "To describe intellectual, motor, and school-associated outcome in young adults with early treated congenital hypothyroidism (CH) and to study the association between long-term outcome and CH variables acting at different points in time during early development (CH severity and early L-thyroxine treatment levels [0-6 years])." | 3.72 | Congenital hypothyroidism: influence of disease severity and L-thyroxine treatment on intellectual, motor, and school-associated outcomes in young adults. ( Heyerdahl, S; Kase, BF; Oerbeck, B; Sundet, K, 2003) |
| "The observation of severe behavioral reactions or learning problems in three teenagers treated with L-thyroxine for juvenile acquired hypothyroidism prompted us to conduct a prospective study of achievement and behavioral characteristics of patients with newly diagnosed juvenile acquired hypothyroidism." | 3.68 | Psychologic and psychoeducational consequences of thyroxine therapy for juvenile acquired hypothyroidism. ( Bailey, JD; Daneman, D; Rovet, JF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibekwe, MU | 1 |
| Ibekwe, RC | 1 |
| Okolo, AA | 1 |
| Cheetham, TD | 1 |
| Ge, JF | 1 |
| Xu, YY | 1 |
| Li, N | 1 |
| Zhang, Y | 1 |
| Qiu, GL | 1 |
| Chu, CH | 1 |
| Wang, CY | 1 |
| Qin, G | 1 |
| Chen, FH | 1 |
| Bitiktaş, S | 1 |
| Kandemir, B | 1 |
| Tan, B | 1 |
| Kavraal, Ş | 1 |
| Liman, N | 1 |
| Dursun, N | 1 |
| Dönmez-Altuntaş, H | 1 |
| Aksan-Kurnaz, I | 1 |
| Suer, C | 1 |
| Rustamov, NM | 1 |
| Kvachadze, ID | 1 |
| Bekaia, GL | 1 |
| Sakvarelidze, ZA | 1 |
| Mitagvaria, NP | 1 |
| Hosseini, M | 1 |
| Dastghaib, SS | 1 |
| Rafatpanah, H | 1 |
| Hadjzadeh, MA | 1 |
| Nahrevanian, H | 1 |
| Farrokhi, I | 1 |
| Huo, K | 1 |
| Zhang, Z | 1 |
| Zhao, D | 1 |
| Li, H | 1 |
| Wang, J | 1 |
| Wang, X | 2 |
| Feng, H | 1 |
| Zhu, C | 1 |
| Oerbeck, B | 1 |
| Sundet, K | 1 |
| Kase, BF | 1 |
| Heyerdahl, S | 1 |
| Pharoah, PO | 1 |
| Connolly, KJ | 1 |
| Moltz, KC | 1 |
| Postellon, DC | 1 |
| Rovet, JF | 2 |
| Daneman, D | 1 |
| Bailey, JD | 1 |
| Tiwari, BD | 1 |
| Godbole, MM | 1 |
| Chattopadhyay, N | 1 |
| Mandal, A | 1 |
| Mithal, A | 1 |
| Ehrlich, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Thyroid Function in Children With Congenital Heart Disease[NCT03496363] | 50 participants (Anticipated) | Observational | 2018-05-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thyroxine and Learning Disabilities
| Article | Year |
|---|---|
Iodine and brain development.
Topics: Animals; Brain; Congenital Hypothyroidism; Female; Humans; Infant; Iodine; Learning Disabilities; Ma | 1995 |
Congenital hypothyroidism and mental development.
Topics: Child; Child, Preschool; Congenital Hypothyroidism; Humans; Hypothyroidism; Infant; Infant, Newborn; | 1994 |
10 other studies available for thyroxine and Learning Disabilities
| Article | Year |
|---|---|
Screening for hypothyroidism in schools for children with learning difficulties in Southeastern Nigeria.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hypothyroidism; Intellect | 2013 |
Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization.
Topics: Animals; Antioxidants; Asymptomatic Diseases; Behavior, Animal; Brain-Derived Neurotrophic Factor; D | 2015 |
Adult-onset hyperthyroidism impairs spatial learning: possible involvement of mitogen-activated protein kinase signaling pathways.
Topics: Animals; CREB-Binding Protein; Disease Models, Animal; Hippocampus; Hyperthyroidism; Learning Disabi | 2016 |
[Iodine deficiency in the prenatal period may form learning ability deficiency in the postnatal period].
Topics: Animals; Diet; Female; Iodine; Learning Disabilities; Pregnancy; Prenatal Nutritional Physiological | 2010 |
Nitric oxide contributes to learning and memory deficits observed in hypothyroid rats during neonatal and juvenile growth.
Topics: Animals; Antithyroid Agents; Female; Hippocampus; Hypothyroidism; Learning Disabilities; Memory Diso | 2010 |
Risk factors for neurodevelopmental deficits in congenital hypothyroidism after early substitution treatment.
Topics: Child Development; Child, Preschool; Congenital Hypothyroidism; Developmental Disabilities; Female; | 2011 |
Congenital hypothyroidism: influence of disease severity and L-thyroxine treatment on intellectual, motor, and school-associated outcomes in young adults.
Topics: Adult; Cognition Disorders; Congenital Hypothyroidism; Educational Measurement; Female; Humans; Hypo | 2003 |
Psychologic and psychoeducational consequences of thyroxine therapy for juvenile acquired hypothyroidism.
Topics: Adolescent; Child; Child Behavior Disorders; Female; Humans; Hypothyroidism; Incidence; Intelligence | 1993 |
Learning disabilities and poor motivation to achieve due to prolonged iodine deficiency.
Topics: Achievement; Adolescent; Aging; Child; Educational Status; Goiter, Endemic; Humans; India; Intellige | 1996 |
Psychoeducational outcome in children with early-treated congenital hypothyroidism.
Topics: Achievement; Child; Child, Preschool; Cohort Studies; Congenital Hypothyroidism; Female; Humans; Hyp | 2000 |