Page last updated: 2024-11-07

thyroxine and Labhart-Willi Syndrome

thyroxine has been researched along with Labhart-Willi Syndrome in 9 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"To describe the response of thyroid-stimulating hormone (TSH) to thyroid-releasing hormone in children and adolescents with Prader-Willi syndrome (PWS), and to compare TSH and total thyroxine (TT4) concentrations measured on neonatal screening for congenital hypothyroidism in children with PWS and controls."3.79Thyroid function from birth to adolescence in Prader-Willi syndrome. ( Berthier, MT; Chanoine, JP; Deal, C; Deladoëy, J; Giguère, Y; Michaud, S; Sharkia, M; Stewart, L; Van Vliet, G, 2013)
"Despite comparable BMI Z-scores and leptin levels, the PWS children exhibited lower fasting insulin and HOMA-IR (homeostasis model assessment of insulin resistance) scores compared to obese controls."3.74Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones. ( Freemark, MS; Grambow, SC; Haqq, AM; Muehlbauer, M; Newgard, CB; Purnell, JQ; Svetkey, LP, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Konishi, A2
Koizumi, M1
Etani, Y2
Ida, S2
Kawai, M2
Shoji, Y1
Sharkia, M1
Michaud, S1
Berthier, MT1
Giguère, Y1
Stewart, L1
Deladoëy, J1
Deal, C1
Van Vliet, G1
Chanoine, JP1
Vaiani, E1
Herzovich, V1
Chaler, E1
Chertkoff, L1
Rivarola, MA1
Torrado, M1
Belgorosky, A1
Nyunt, O1
Cotterill, AM1
Archbold, SM1
Wu, JY1
Leong, GM1
Verge, CF1
Crock, PA1
Ambler, GR1
Hofman, P1
Harris, M1
Butler, MG1
Theodoro, M1
Skouse, JD1
Haqq, AM1
Muehlbauer, M1
Svetkey, LP1
Newgard, CB1
Purnell, JQ1
Grambow, SC1
Freemark, MS1
Festen, DA1
Visser, TJ1
Otten, BJ1
Wit, JM1
Duivenvoorden, HJ1
Hokken-Koelega, AC1
Costeff, H1
Holm, VA1
Ruvalcaba, R1
Shaver, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evidence-Based Approach to Dietary Management of Prader-Willi Syndrome (PWS)[NCT02011360]10 participants (Actual)Interventional2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for thyroxine and Labhart-Willi Syndrome

ArticleYear
Thyroid hormone levels in children with Prader-Willi syndrome before and during growth hormone treatment.
    Clinical endocrinology, 2007, Volume: 67, Issue:3

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Human Growth Hormone; Humans; Insulin-Like Growt

2007

Other Studies

8 other studies available for thyroxine and Labhart-Willi Syndrome

ArticleYear
Very young children with Prader-Willi syndrome are refractory to growth hormone-associated decreases in free thyroxine levels.
    Endocrine journal, 2023, May-29, Volume: 70, Issue:5

    Topics: Child; Child, Preschool; Female; Human Growth Hormone; Humans; Infant; Male; Prader-Willi Syndrome;

2023
Central hypothyroidism improves with age in very young children with Prader-Willi syndrome.
    Clinical endocrinology, 2021, Volume: 94, Issue:3

    Topics: Age Factors; Child, Preschool; Humans; Hypothyroidism; Infant; Prader-Willi Syndrome; Retrospective

2021
Thyroid function from birth to adolescence in Prader-Willi syndrome.
    The Journal of pediatrics, 2013, Volume: 163, Issue:3

    Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hypothyroidis

2013
Thyroid axis dysfunction in patients with Prader-Willi syndrome during the first 2 years of life.
    Clinical endocrinology, 2010, Volume: 73, Issue:4

    Topics: Female; Humans; Hypothalamo-Hypophyseal System; Infant; Infant, Newborn; Male; Prader-Willi Syndrome

2010
Normal cortisol response on low-dose synacthen (1 microg) test in children with Prader Willi syndrome.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:12

    Topics: Adrenocorticotropic Hormone; Australasia; Body Mass Index; Child; Child, Preschool; Cosyntropin; Fem

2010
Thyroid function studies in Prader-Willi syndrome.
    American journal of medical genetics. Part A, 2007, Mar-01, Volume: 143A, Issue:5

    Topics: Adolescent; Adult; Child; Female; Humans; Hypothyroidism; Male; Prader-Willi Syndrome; Risk Factors;

2007
Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones.
    Clinical endocrinology, 2007, Volume: 67, Issue:6

    Topics: Adiponectin; Adolescent; Child; Female; Gastric Inhibitory Polypeptide; Ghrelin; Humans; Insulin; In

2007
Growth hormone secretion in Prader-Willi syndrome.
    Acta paediatrica Scandinavica, 1990, Volume: 79, Issue:11

    Topics: Child; Female; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Prader-Willi Syndrome; Th

1990