thyroxine has been researched along with Klinefelter Syndrome in 10 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Those affected by Klinefelter's syndrome are at increased risk of systemic lupus erythematosus, breast cancer, non-Hodgkin's lymphoma, and lung cancer." | 1.46 | An enigmatic trio of Klinefelter's syndrome, autoimmune hypothyroidism and nephrotic syndrome. ( Aggarwal, HK; Jain, D; Jain, P; Rao, A, 2017) |
| "Klinefelter syndrome has been associated with thyroid abnormalities, the genesis of which is not yet fully clear." | 1.46 | A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome. ( Anzuini, A; Granato, S; Lenzi, A; Panimolle, F; Radicioni, AF; Ruga, G; Spaziani, M; Tahani, N, 2017) |
| "In eleven patients with Klinefelter's Syndrome TSH, T4 and T3 levels have been measured after stimulation with TRH." | 1.26 | Response to thyrotrophin releasing hormone in Klinefelter's syndrome. ( Fyffe, JA; Lidgard, GP; Price, WH; Renton, WB; Yap, PL, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, A | 1 |
| Jain, D | 1 |
| Aggarwal, HK | 1 |
| Jain, P | 1 |
| Tahani, N | 1 |
| Ruga, G | 1 |
| Granato, S | 1 |
| Spaziani, M | 1 |
| Panimolle, F | 1 |
| Anzuini, A | 1 |
| Lenzi, A | 1 |
| Radicioni, AF | 1 |
| Bjørn, AM | 1 |
| Bojesen, A | 1 |
| Gravholt, CH | 1 |
| Laurberg, P | 1 |
| DEMOWBRAY, RR | 1 |
| Brook, CG | 1 |
| Smals, AG | 1 |
| Kloppenborg, PW | 1 |
| Lequin, RL | 1 |
| Beex, L | 1 |
| Ross, A | 1 |
| Benraad, TJ | 1 |
| Yap, PL | 1 |
| Renton, WB | 1 |
| Price, WH | 1 |
| Fyffe, JA | 1 |
| Lidgard, GP | 1 |
| Kley, HK | 1 |
| Herrmann, J | 1 |
| Morgner, KD | 1 |
| Krüskemper, HL | 1 |
| Moses, AM | 1 |
| Miller, M | 1 |
| Hamilton, W | 1 |
10 other studies available for thyroxine and Klinefelter Syndrome
| Article | Year |
|---|---|
An enigmatic trio of Klinefelter's syndrome, autoimmune hypothyroidism and nephrotic syndrome.
Topics: Adult; Comorbidity; Hashimoto Disease; Humans; Klinefelter Syndrome; Male; Nephrotic Syndrome; Ramip | 2017 |
A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome.
Topics: Adolescent; Child; Humans; Hypothyroidism; Klinefelter Syndrome; Male; Puberty; Thyroid Function Tes | 2017 |
Hypothyroidism secondary to hypothalamic-pituitary dysfunction may be part of the phenotype in klinefelter syndrome: a case-control study.
Topics: Adult; Autoantibodies; Case-Control Studies; Hormone Replacement Therapy; Humans; Hypothalamic Disea | 2009 |
THE HORMONES AND PUBERTY.
Topics: Adolescent; Child; Chorionic Gonadotropin; Cryptorchidism; Diethylstilbestrol; Ethinyl Estradiol; Eu | 1964 |
Obesity: the fat child.
Topics: Adipose Tissue; Adult; Child; Child Development; Child, Preschool; Diagnosis, Differential; Diet, Re | 1980 |
The pituitary-thyroid axis in Klinefelter's syndrome.
Topics: Adult; Humans; Klinefelter Syndrome; Male; Pituitary Gland; Pituitary Gland, Anterior; Secretory Rat | 1977 |
Response to thyrotrophin releasing hormone in Klinefelter's syndrome.
Topics: Adult; Aged; Humans; Klinefelter Syndrome; Male; Middle Aged; Thyrotropin; Thyrotropin-Releasing Hor | 1978 |
Effects of testosterone oenanthate on plasma concentrations of thyroxine, cortisol, testosterone and hormone binding proteins in patients with hypogonadism.
Topics: Adolescent; Adult; Binding, Competitive; Blood Proteins; Body Weight; Chromatography, Paper; Humans; | 1973 |
Stimulation and inhibition of ACTH release in patients with pituitary disease.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adrenocorticotropic Hormone; Adult; Aged; Dexamethasone; Diab | 1968 |
Abnormal height in children.
Topics: Adrenocorticotropic Hormone; Anabolic Agents; Body Height; Child; Estrogens; Growth; Growth Disorder | 1969 |