Page last updated: 2024-11-06

thyroxine and Jaundice, Neonatal

thyroxine has been researched along with Jaundice, Neonatal in 18 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.

Research Excerpts

ExcerptRelevanceReference
"The relationships between biochemical severity of hypothyroidism (as judged by plasma thyroxine) and the clinical and radiographic findings at diagnosis were evaluated in 449 infants born in 1982-4 with congenital hypothyroidism identified by neonatal screening."3.68Congenital hypothyroidism detected by neonatal screening: relationship between biochemical severity and early clinical features. ( Chapple, J; Fuggle, PW; Grant, DB; Smith, I; Tokar, S, 1992)
"Maternal hypothyroidism has been reported to have concerns over neonatal outcomes, not only in the context of neurocognitive development but also in the short term as birth weight and neonatal jaundice."1.62Neonatal outcomes and congenital anomalies in pregnancies affected by hypothyroidism. ( Humayun, KN; Islam, N; Kiran, Z; Sheikh, A, 2021)
"There was a 73% less chance of gestational hypertension for thyroid autoimmune groups."1.62Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4). ( Islam, N; Kiran, Z; Sheikh, A, 2021)
"Congenital hypothyroidism is one of the most urgent diseases of the neonate."1.35Neonatal sludge: a finding of congenital hypothyroidism. ( Akın, L; Akın, MA; Coban, D; Kurtoğlu, S; Yıkılmaz, A, 2009)
"The effect of neonatal jaundice, a potential confounder of neonatal SEP, was also evaluated."1.28Somatosensory evoked potentials in neonates with primary congenital hypothyroidism during the first week of therapy. ( Bongers-Schokking, CJ; Colon, EJ; de Groot, CJ; Hoogland, RA; Van den Brande, JL, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's4 (22.22)18.2507
2000's1 (5.56)29.6817
2010's1 (5.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Kiran, Z2
Sheikh, A2
Humayun, KN1
Islam, N2
Oliveira, GN1
Dinis, I1
Noruegas, MJ1
Mirante, A1
Kurtoğlu, S1
Coban, D1
Akın, MA1
Akın, L1
Yıkılmaz, A1
Bosco, M1
Bacolla, A1
Castelli, G1
Godano, A1
Leo, D1
Merlin, P1
Pennacino, G1
Pilotti, G1
Mathew, PM1
Wharton, BA1
Strbák, V1
Huttová, M1
Földes, O1
Alexandrová, M1
Macho, L1
Ondrejková, V1
Rusnák, M1
Randolph, VS1
Medaglia, R1
Krauel, J1
Molina, V1
Baraibar, R1
Krüger, C1
Dörr, HG1
Becker, W1
Wolf, F1
Harms, D1
Tan, KL1
Chirino-Barcelo, Y1
Aw, TC1
Joseph, R1
Conney, AH1
Jacobson, MM1
Levin, W1
Grant, DB1
Smith, I1
Fuggle, PW1
Tokar, S1
Chapple, J1
Bongers-Schokking, CJ1
Colon, EJ1
Hoogland, RA1
de Groot, CJ1
Van den Brande, JL1
Lanes, R1
Borges, M1
Moret, LA1
Febres, F1
Lüders, D1
Reynolds, JW1

Reviews

4 reviews available for thyroxine and Jaundice, Neonatal

ArticleYear
Four clinical chemistry analyses for pediatric patients: glycosylated hemoglobin, free bilirubin, sweat electrolytes, neonatal thyroxine.
    The American journal of medical technology, 1982, Volume: 48, Issue:1

    Topics: Bilirubin; Congenital Hypothyroidism; Cystic Fibrosis; Diabetes Mellitus, Type 1; Electrolytes; Glyc

1982
Effects of drugs on the metabolism of bilirubin and other normal body constituents.
    Birth defects original article series, 1976, Volume: 12, Issue:2

    Topics: Animals; Bilirubin; DDT; Estrogens; Female; Glucuronates; Humans; Hydroxylation; Infant; Infant, New

1976
[The pros and cons of luminal teatment of hyperbilirubinemia].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Bilirubin; Central Nervous System; Cholesterol; Drug Eruptions

1970
The use of drugs in influencing human fetal metabolism.
    Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Blood Transfusion, Intrauterine; Congenital Hypothyroidism; E

1974

Trials

1 trial available for thyroxine and Jaundice, Neonatal

ArticleYear
Effect of phototherapy on thyroid stimulatory hormone and free thyroxine levels.
    Journal of paediatrics and child health, 1996, Volume: 32, Issue:6

    Topics: Humans; Infant, Newborn; Jaundice, Neonatal; Phototherapy; Reference Values; Thyroid Function Tests;

1996

Other Studies

13 other studies available for thyroxine and Jaundice, Neonatal

ArticleYear
Neonatal outcomes and congenital anomalies in pregnancies affected by hypothyroidism.
    Annals of medicine, 2021, Volume: 53, Issue:1

    Topics: Adult; Birth Weight; Cesarean Section; Cross-Sectional Studies; Female; Fetal Distress; Humans; Hypo

2021
Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4).
    BMC pregnancy and childbirth, 2021, Feb-15, Volume: 21, Issue:1

    Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Apgar Score; Autoantibodies; Autoimmune Diseases;

2021
A rare cause of neonatal persistent jaundice.
    BMJ case reports, 2017, Dec-22, Volume: 2017

    Topics: Adrenal Glands; Adrenal Insufficiency; Anti-Inflammatory Agents; Cytomegalovirus Infections; Diabete

2017
Neonatal sludge: a finding of congenital hypothyroidism.
    Journal of clinical research in pediatric endocrinology, 2009, Volume: 1, Issue:4

    Topics: Congenital Hypothyroidism; Gallbladder Diseases; Humans; Infant, Newborn; Jaundice, Neonatal; Male;

2009
[Phototherapy in neonatal hyperbilirubinemia and evaluation of T3, T4 and TSH].
    Minerva pediatrica, 1984, Jun-30, Volume: 36, Issue:12

    Topics: Female; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Phototherapy; Thyrotropin; Thyroxine; Tri

1984
Investigation and management of neonatal jaundice: a problem-orientated case record.
    Archives of disease in childhood, 1981, Volume: 56, Issue:12

    Topics: Bilirubin; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Hypothyroidism; Infant, New

1981
Exchange transfusion in newborns: rapid fall of plasma thyroid hormones and attenuated TSH response up to 48 hours.
    Endocrinologia experimentalis, 1982, Volume: 16, Issue:1

    Topics: Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Humans; Infant, Newborn; Jaundic

1982
[Immaturity for gestational age and neonatal thyroid dysfunction].
    Anales espanoles de pediatria, 1982, Volume: 17, Issue:3

    Topics: Congenital Hypothyroidism; Female; Gestational Age; Humans; Hyaline Membrane Disease; Hypothyroidism

1982
[Neonatal hyperthyroidism in non-diagnosed Basedow's disease of the mother. Problems of diagnosis and therapy illustrated by a case history].
    Deutsche medizinische Wochenschrift (1946), 1994, Oct-07, Volume: 119, Issue:40

    Topics: Adult; Bilirubin; C-Reactive Protein; Drug Therapy, Combination; Female; Graves Disease; Hepatomegal

1994
[Combined pituitary insufficiency in an infant].
    Monatsschrift fur Kinderheilkunde, 1976, Volume: 124, Issue:5

    Topics: Humans; Hydrocortisone; Hypoglycemia; Hypogonadism; Infant; Infant, Newborn; Jaundice, Neonatal; Mal

1976
Congenital hypothyroidism detected by neonatal screening: relationship between biochemical severity and early clinical features.
    Archives of disease in childhood, 1992, Volume: 67, Issue:1

    Topics: Adult; Birth Weight; Bone Development; Congenital Hypothyroidism; Delivery, Obstetric; Female; Gesta

1992
Somatosensory evoked potentials in neonates with primary congenital hypothyroidism during the first week of therapy.
    Pediatric research, 1991, Volume: 30, Issue:1

    Topics: Age Determination by Skeleton; Age Factors; Congenital Hypothyroidism; Evoked Potentials, Somatosens

1991
Evaluation of the pituitary-thyroidal axis in newborns undergoing exchange transfusion.
    European journal of pediatrics, 1986, Volume: 145, Issue:1-2

    Topics: Exchange Transfusion, Whole Blood; Humans; Infant, Newborn; Jaundice, Neonatal; Pituitary Gland, Ant

1986