thyroxine has been researched along with Injuries, Radiation in 39 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with primary thyroid failure on levothyroxine (LT4) replacement who develop nephrotic syndrome (NS) may rarely present with an increase in LT4 requirements." | 7.70 | Increased levothyroxine requirements presenting as "inappropriate" TSH secretion syndrome in a patient with nephrotic syndrome. ( Balow, JE; Collins, MT; Csako, G; Pucino, F; Remaley, AT; Sarlis, NJ; Skarulis, MC, 2000) |
| " Biochemical hypothyroidism was defined as an elevated level of serum thyroid-stimulating hormone (TSH) value with a normal or decreased level of serum free thyroxine (fT4) after radiotherapy." | 3.88 | Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients. ( Gao, X; He, B; Li, M; Lin, Z; Luo, R; Wang, D; Wu, VWC; Xu, Z; Yang, Z, 2018) |
| " The study group consisted of 16 patients who had been diagnosed with hyperthyroidism, were treated with radioiodine, developed hypothyroidism after treatment, and finally became euthyroid on l-thyroxine substitution." | 3.80 | Individual plasma ghrelin changes in the same patients in hyperthyroid, hypothyroid and euthyroid state. ( Gurgul, E; Moczko, J; Ruchala, M; Stangierski, A; Wrotkowska, E, 2014) |
| " Here we report an unusual case with radiation-induced hypothyroidism who had undergone hemithyroidectomy for adenomatous goiter 8 years before the radiotherapy for nasopharyngeal cancer and subclinical hyperthyroidism due to Graves' disease developed during thyroxine replacement therapy." | 3.74 | Development of subclinical hyperthyroidism due to Graves' disease in a hypothyroid woman who had undergone hemithyroidectomy for adenomatous goiter and radiotherapy for nasopharyngeal cancer. ( Hoshikawa, S; Ito, S; Mori, K; Nakagawa, Y; Ozaki, H; Yoshida, K, 2007) |
| " Here we describe four patients who illustrate how conventional radiotherapy after cancer mammae surgery gave rise to hypothyroidism, how fine needle aspiration biopsy of the thyroid gland can help in the diagnosis of autoimmune thyroiditis, and a patient without hypothyroidism who was treated with thyroxine and triiodothyronine." | 3.71 | [Hypothyroidism--a manifold clinical view]. ( Norheim, I; Thorsby, A, 2002) |
| "Patients with primary thyroid failure on levothyroxine (LT4) replacement who develop nephrotic syndrome (NS) may rarely present with an increase in LT4 requirements." | 3.70 | Increased levothyroxine requirements presenting as "inappropriate" TSH secretion syndrome in a patient with nephrotic syndrome. ( Balow, JE; Collins, MT; Csako, G; Pucino, F; Remaley, AT; Sarlis, NJ; Skarulis, MC, 2000) |
| "This study was undertaken in 68 thyrotoxic patients to assess the predictive value of various post treatment biochemical and immunological tests for early hypothyroidism after I131 therapy and to determine whether pretreatment with carbimazole protects against post I131 therapy hypothyroidism." | 3.69 | Thyrotoxicosis--treatment by I131 therapy and early prediction of hypothyroidism following this therapy. ( Jain, SK; Khanna, CM; Walia, RP, 1994) |
| " The children who received a dose of more than 30 rad for the thyroid manifested primary response in the form of euthyroid hyperthyroxinemia, a high risk of the development in future of autoimmune diseases in the lack of hypothyrosis." | 3.68 | [Clinical-immunological characteristics of the state of the thyroid gland in children exposed to ionizing radiation because of the Chernobyl AES accident]. ( Afanas'ev, DE; Avramenko, NL; Cheban, AK; Chumak, AA; Dekhtiareva, OS; Kopylova, OV; Taranenko, MG, 1991) |
| "The effect of radiation-induced anorexia on serum thyrotropin (TSH), pituitary TSH-beta mRNA, pituitary TSH content, serum thyroxine (T4), and serum 3,5,3'-triiodothyronine (T3) was investigated using feed-matched controls." | 3.68 | Effects of irradiation and semistarvation on rat thyrotropin beta subunit messenger ribonucleic acid, pituitary thyrotropin content, and thyroid hormone levels. ( Carr, FE; Fein, HG; Litten, RZ; Smallridge, RC, 1990) |
| "Primary hypothyroidism is one of the late complications that can occur after radiation therapy for malignant tumors in the head and neck region." | 1.56 | Model-based calculation of thyroid gland normal tissue complication probability in head and neck cancer patients after radiation therapy. ( Balentová, S; Ďuroška, M; Hajtmanová, E; Kinclová, I; Kozlíková, K; Matula, P; Muríň, P, 2020) |
| "Hypothyroidism is an established adverse effect of radiation therapy for head and neck cancer, and computed tomography (CT) density of the thyroid gland is lower in hypothyroid than euthyroid individuals." | 1.48 | Computed Tomography Density Change in the Thyroid Gland Before and After Radiation Therapy. ( Aizawa, T; Ishibashi, N; Maebayashi, T; Matsushita, J; Okada, M; Sakaguchi, M, 2018) |
| "Radiation-induced hypothyroidism is the most common thyroid disorder after radiotherapy in nasopharyngeal carcinoma (NPC) patients." | 1.48 | Pattern of radiation-induced thyroid gland changes in nasopharyngeal carcinoma patients in 48 months after radiotherapy. ( Gao, X; He, B; Lin, Z; Tam, SY; Wang, D; Wu, VWC; Yang, Z, 2018) |
| "A total of 114 patients with head and neck cancer whose radiotherapy fields included the thyroid gland were analysed." | 1.40 | Dose-volumetric parameters for predicting hypothyroidism after radiotherapy for head and neck cancer. ( Kim, MY; Wu, HG; Yu, T, 2014) |
| "To determine the dose-response relationship of the thyroid for radiation-induced hypothyroidism in head-and-neck radiation therapy, according to 6 normal tissue complication probability models, and to find the best-fit parameters of the models." | 1.39 | Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy. ( Bakhshandeh, M; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A; Vasheghani, M, 2013) |
| "Radiation-induced thyroiditis is regarded as primary damage to the thyroid gland." | 1.38 | Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography. ( Bakhshandeh, M; Edraki, HR; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A, 2012) |
| "After irradiation of the neck for a squamous cell carcinoma of the tonsillar pillar and vocal cord, a 71-year-old man presented with a rapidly progressive sleep apnea syndrome." | 1.28 | Sleep apnea syndrome after irradiation of the neck. ( Dietrich, RA; Herlihy, JP; Shaw, T; Whitlock, WL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (38.46) | 18.7374 |
| 1990's | 6 (15.38) | 18.2507 |
| 2000's | 5 (12.82) | 29.6817 |
| 2010's | 12 (30.77) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kinclová, I | 1 |
| Hajtmanová, E | 1 |
| Matula, P | 1 |
| Balentová, S | 1 |
| Muríň, P | 1 |
| Ďuroška, M | 1 |
| Kozlíková, K | 1 |
| Ishibashi, N | 1 |
| Maebayashi, T | 1 |
| Aizawa, T | 1 |
| Sakaguchi, M | 1 |
| Okada, M | 1 |
| Matsushita, J | 1 |
| Luo, R | 1 |
| Wu, VWC | 2 |
| He, B | 2 |
| Gao, X | 2 |
| Xu, Z | 1 |
| Wang, D | 2 |
| Yang, Z | 2 |
| Li, M | 1 |
| Lin, Z | 3 |
| Tam, SY | 1 |
| Campennì, A | 1 |
| Amato, E | 1 |
| Laudicella, R | 1 |
| Alibrandi, A | 1 |
| Cardile, D | 1 |
| Pignata, SA | 1 |
| Trimarchi, F | 1 |
| Ruggeri, RM | 1 |
| Auditore, L | 1 |
| Baldari, S | 1 |
| Ruchala, M | 1 |
| Gurgul, E | 1 |
| Stangierski, A | 1 |
| Wrotkowska, E | 1 |
| Moczko, J | 1 |
| Kim, MY | 1 |
| Yu, T | 1 |
| Wu, HG | 1 |
| Cann, RC | 1 |
| Marks, DJ | 1 |
| Hurel, SJ | 1 |
| Laing, C | 1 |
| Leith, JT | 1 |
| Davis, PJ | 1 |
| Mousa, SA | 1 |
| Hercbergs, AA | 1 |
| van de Donk, NW | 1 |
| America, YG | 1 |
| Zelissen, PM | 1 |
| Hamer, BJ | 1 |
| Kawaguchi, G | 1 |
| Abe, E | 1 |
| Sasamoto, R | 1 |
| Sasai, K | 1 |
| Wu, VW | 1 |
| Lin, J | 1 |
| Feng, H | 1 |
| Chen, L | 1 |
| Bakhshandeh, M | 2 |
| Hashemi, B | 2 |
| Mahdavi, SR | 2 |
| Nikoofar, A | 2 |
| Edraki, HR | 1 |
| Kazemnejad, A | 2 |
| Vasheghani, M | 1 |
| LAGUN, MA | 1 |
| REZONTOV, VA | 1 |
| AKOEV, IG | 1 |
| LEMAIRE, M | 3 |
| CLOSON, J | 3 |
| RAHMAN, YE | 1 |
| HIETBRINK, BE | 1 |
| KESHMIRI, M | 1 |
| FISHER, DA | 1 |
| Nakagawa, Y | 1 |
| Mori, K | 1 |
| Hoshikawa, S | 1 |
| Ozaki, H | 1 |
| Ito, S | 1 |
| Yoshida, K | 1 |
| Holten, I | 1 |
| Sowers, JR | 1 |
| Resch, G | 1 |
| Walker, S | 1 |
| Sollars, E | 1 |
| Turner, SL | 1 |
| Tiver, KW | 1 |
| Boyages, SC | 1 |
| Khanna, CM | 1 |
| Jain, SK | 1 |
| Walia, RP | 1 |
| Kubota, M | 1 |
| Shinozaki, M | 1 |
| Sasaki, H | 1 |
| Shafford, EA | 1 |
| Kingston, JE | 1 |
| Healy, JC | 1 |
| Webb, JA | 1 |
| Plowman, PN | 1 |
| Reznek, RH | 1 |
| Collins, MT | 1 |
| Remaley, AT | 1 |
| Csako, G | 1 |
| Pucino, F | 1 |
| Skarulis, MC | 1 |
| Balow, JE | 1 |
| Sarlis, NJ | 1 |
| van Santen, HM | 1 |
| de Kraker, J | 1 |
| van Eck, BL | 1 |
| de Vijlder, JJ | 1 |
| Vulsma, T | 1 |
| Norheim, I | 1 |
| Thorsby, A | 1 |
| Shalet, SM | 1 |
| Beardwell, CG | 1 |
| MacFarlane, IA | 1 |
| Jones, PH | 1 |
| Pearson, D | 1 |
| Cheban, AK | 1 |
| Dekhtiareva, OS | 1 |
| Kopylova, OV | 1 |
| Chumak, AA | 1 |
| Afanas'ev, DE | 1 |
| Taranenko, MG | 1 |
| Avramenko, NL | 1 |
| Litten, RZ | 1 |
| Carr, FE | 1 |
| Fein, HG | 1 |
| Smallridge, RC | 1 |
| Herlihy, JP | 1 |
| Whitlock, WL | 1 |
| Dietrich, RA | 1 |
| Shaw, T | 1 |
| Abdel-Nabi, H | 1 |
| Waldman, WJ | 1 |
| Hinkle, GH | 1 |
| Miller, EA | 1 |
| Trembath, L | 1 |
| Olsen, JO | 1 |
| Martin, EW | 1 |
| Reboul, J | 1 |
| Caille, JM | 1 |
| Bellet, M | 1 |
| Tessier, JP | 1 |
39 other studies available for thyroxine and Injuries, Radiation
| Article | Year |
|---|---|
Model-based calculation of thyroid gland normal tissue complication probability in head and neck cancer patients after radiation therapy.
Topics: Adult; Aged; Algorithms; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Dose-Response Rela | 2020 |
Computed Tomography Density Change in the Thyroid Gland Before and After Radiation Therapy.
Topics: Adult; Aged; Aged, 80 and over; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middl | 2018 |
Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients.
Topics: Adolescent; Adult; Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Models, Biological; Naso | 2018 |
Pattern of radiation-induced thyroid gland changes in nasopharyngeal carcinoma patients in 48 months after radiotherapy.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hypothyroidism; Incidence; Male; Middle Aged; Nasoph | 2018 |
Recombinant human thyrotropin (rhTSH) versus Levo-thyroxine withdrawal in radioiodine therapy of differentiated thyroid cancer patients: differences in abdominal absorbed dose.
Topics: Abdomen; Adenocarcinoma; Drug Administration Schedule; Female; Gastrointestinal Absorption; Humans; | 2019 |
Individual plasma ghrelin changes in the same patients in hyperthyroid, hypothyroid and euthyroid state.
Topics: Female; Ghrelin; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Radiation Inju | 2014 |
Dose-volumetric parameters for predicting hypothyroidism after radiotherapy for head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Head and Neck Neoplasms; Huma | 2014 |
Acute kidney injury after Chernobyl.
Topics: Acute Kidney Injury; Chernobyl Nuclear Accident; Hormone Replacement Therapy; Humans; Hydroxymethylg | 2015 |
In vitro effects of tetraiodothyroacetic acid combined with X-irradiation on basal cell carcinoma cells.
Topics: Carcinoma, Basal Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Breaks, | 2017 |
Takotsubo cardiomyopathy following radioiodine therapy for toxic multinodular goitre.
Topics: Aged; Dyspnea; Goiter, Nodular; Humans; Iodine Radioisotopes; Male; Radiation Injuries; Risk Factors | 2009 |
Elevation of serum carcinoembryonic antigen level in a patient with hypothyroidism after radiation therapy for cervical esophageal cancer.
Topics: Biomarkers, Tumor; Carcinoembryonic Antigen; Esophageal Neoplasms; Female; Humans; Hypothyroidism; M | 2010 |
A longitudinal study on the radiation-induced thyroid gland changes after external beam radiotherapy of nasopharyngeal carcinoma.
Topics: Adult; Aged; Carcinoma; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nasopharyngeal Carc | 2011 |
Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography.
Topics: Adult; Aged; Aged, 80 and over; Arteries; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged | 2012 |
Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Confidence Intervals; Dose-Response Relationship, Radiation; Female; | 2013 |
[Effect of thyroidin on the restoration of organic reactivity following acute radiation sickness].
Topics: Gas Gangrene; Immunity; Radiation Injuries; Radiation Injuries, Experimental; Thyroid Hormones; Thyr | 1962 |
[Effect of thyroidin on erythropoiesis in irradiated animals].
Topics: Animals; Erythropoiesis; Radiation Injuries; Radiation Injuries, Experimental; Thyroid Hormones; Thy | 1962 |
[SUBCUTANEOUS RESORPTION OF THYROXIN AND 3,5,3'-TRIIODO-L-THYRONINE, IN THE NORMAL RAT AND THE RAT SUBJECTED TO LETHAL X-IRRADIATION].
Topics: Absorption; Chromatography; Electrophoresis; Iodine Isotopes; Physiological Phenomena; Radiation Inj | 1963 |
[OXYGEN CONSUMPTION IN THE RAT SUBJECTED TO A LETHAL X-IRRADIATION: ABSENCE OF SIGNIFICANT RESPONSE TO THE ADMINISTRATION OF THYROXIN AND TRIIODOTHYRONINE].
Topics: Animals; Metabolism; Oxygen Consumption; Pharmacology; Radiation Injuries; Radiation Injuries, Exper | 1963 |
[BIOLOGICAL HALF-LIFE ON L-THYROXINE AND 3,5,3'-TRIIODO-L-THYRONINE-I-131 IN THE RAT SUBJECTED TO LETHAL DOSE TOTAL-BODY X-IRRADIATION].
Topics: Amino Acids, Aromatic; Half-Life; Iodine; Iodine Isotopes; Metabolism; Radiation Injuries; Radiation | 1963 |
EFFECT OF X-IRRADIATION ON THE FRAGILITY OF RAT SPLEEN LYSOSOMES.
Topics: Acid Phosphatase; Adrenalectomy; Animals; Detergents; Lysosomes; Pharmacology; Radiation Injuries; R | 1963 |
THE EFFECTS OF IONIZING RADIATIONS ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. I. INFLUENCE OF X-IRRADIATION ON THE DEVELOPMENT OF A THIOPHOSPHATE-OXIDIZING ENZYME SYSTEM IN THE LIVERS OF MALE RATS. QUART PROGR REP 50.
Topics: Adrenal Cortex Hormones; Liver; Metabolism; Organophosphate Poisoning; Pharmacology; Phosphates; Pho | 1964 |
MANAGEMENT OF HYPOTHYROIDISM DURING INFANCY AND CHILDHOOD.
Topics: Adolescent; Alkaline Phosphatase; Antithyroid Agents; Body Height; Body Weight; Child; Cholesterol; | 1964 |
[COMPLEMENTARY STUDY OF THE OXYGEN CONSUMPTION OF RATS SUBJECTED TO LETHAL X-IRRADIATION].
Topics: Metabolism; Oxygen Consumption; Pharmacology; Radiation Injuries; Radiation Injuries, Experimental; | 1964 |
Development of subclinical hyperthyroidism due to Graves' disease in a hypothyroid woman who had undergone hemithyroidectomy for adenomatous goiter and radiotherapy for nasopharyngeal cancer.
Topics: Adult; Carcinoma; Female; Goiter, Nodular; Graves Disease; Hormone Replacement Therapy; Humans; Hype | 2007 |
Acute response of the thyroid to external radiation.
Topics: Adult; Aged; Animals; Autoantibodies; Biopsy, Needle; Cell Nucleus; Cytoplasm; Female; Follow-Up Stu | 1983 |
Developmental patterns of the hypothalamic-pituitary axis in the euthyroid and hypothyroid male rat.
Topics: Aging; Animals; Animals, Newborn; Gonadotropin-Releasing Hormone; Haloperidol; Hypothalamo-Hypophyse | 1980 |
Thyroid dysfunction following radiotherapy for head and neck cancer.
Topics: Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middle Aged; Radia | 1995 |
Thyrotoxicosis--treatment by I131 therapy and early prediction of hypothyroidism following this therapy.
Topics: Adult; Aged; Antibodies; Carbimazole; Female; Follow-Up Studies; Forecasting; Humans; Hypothyroidism | 1994 |
[Circadian rhythm disturbance after radiotherapy for brain tumor in infantile period--clinical effect of L-thyroxine and vitamin B12].
Topics: Adult; Astrocytoma; Brain Neoplasms; Circadian Rhythm; Cranial Irradiation; Humans; Hypothalamo-Hypo | 1993 |
Thyroid nodular disease after radiotherapy to the neck for childhood Hodgkin's disease.
Topics: Adolescent; Biopsy, Needle; Child; Child, Preschool; Dose-Response Relationship, Radiation; Female; | 1999 |
Increased levothyroxine requirements presenting as "inappropriate" TSH secretion syndrome in a patient with nephrotic syndrome.
Topics: Adult; Dose-Response Relationship, Drug; Graves Disease; Humans; Hyperpituitarism; Male; Nephrotic S | 2000 |
High incidence of thyroid dysfunction despite prophylaxis with potassium iodide during (131)I-meta-iodobenzylguanidine treatment in children with neuroblastoma.
Topics: 3-Iodobenzylguanidine; Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Follow-Up Studi | 2002 |
[Hypothyroidism--a manifold clinical view].
Topics: Adult; Diagnosis, Differential; Female; Humans; Hypothyroidism; Male; Middle Aged; Radiation Injurie | 2002 |
Endocrine morbidity in adults treated with cerebral irradiation for brain tumours during childhood.
Topics: Adolescent; Adult; Blood Glucose; Body Height; Brain Neoplasms; Child; Dose-Response Relationship, R | 1977 |
[Clinical-immunological characteristics of the state of the thyroid gland in children exposed to ionizing radiation because of the Chernobyl AES accident].
Topics: Accidents; Autoimmune Diseases; Child; Humans; Nuclear Reactors; Radiation Dosage; Radiation Injurie | 1991 |
Effects of irradiation and semistarvation on rat thyrotropin beta subunit messenger ribonucleic acid, pituitary thyrotropin content, and thyroid hormone levels.
Topics: Animals; Anorexia; Body Weight; DNA Probes; Male; Oligonucleotide Probes; Pituitary Gland, Anterior; | 1990 |
Sleep apnea syndrome after irradiation of the neck.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Hypothyroidism; Laryngeal Edema; Laryngeal Neoplasms; Male; | 1989 |
Comparison of L-thyroxine and a saturated solution of potassium iodide in preventing damage to the thyroid following iodine-131-labeled antibody injection.
Topics: Animals; DNA Damage; Iodine Radioisotopes; Male; Potassium Iodide; Radiation Injuries; Rats; Rats, I | 1987 |
[Treatment of Basedow hyperthyroidism by protracted doses of radioactive iodine].
Topics: Female; Graves Disease; Humans; Hyperthyroidism; Iodine Isotopes; Long-Term Care; Middle Aged; Myxed | 1969 |