thyroxine has been researched along with Inborn Errors of Metabolism in 36 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Familial dysalbuminemic hyperthyroxinemia (FDH) is a familial autosomal dominant syndrome caused by abnormal albumin with an increased affinity for thyroxine (T4)." | 7.72 | Artifactually elevated serum-free thyroxine levels measured by equilibrium dialysis in a pregnant woman with familial dysalbuminemic hyperthyroxinemia. ( Hoshikawa, S; Ito, S; Kaise, N; Mori, K; Nakagawa, Y; Yoshida, K, 2004) |
| "Familial dysalbuminemic hyperthyroxinemia (FDH) is a familial autosomal dominant syndrome caused by abnormal albumin with an increased affinity for thyroxine (T4)." | 3.72 | Artifactually elevated serum-free thyroxine levels measured by equilibrium dialysis in a pregnant woman with familial dysalbuminemic hyperthyroxinemia. ( Hoshikawa, S; Ito, S; Kaise, N; Mori, K; Nakagawa, Y; Yoshida, K, 2004) |
| "Congenital hypothyroidism is a common preventable cause of mental retardation." | 2.40 | Congenital hypothyroidism: etiologies, diagnosis, and management. ( LaFranchi, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (88.89) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pieroni, KP | 1 |
| Bass, D | 1 |
| WIENER, JD | 1 |
| LINDEBOOM, GA | 1 |
| MURRAY, P | 1 |
| THOMSON, JA | 2 |
| MCGIRR, EM | 1 |
| WALLACE, TJ | 2 |
| MACDONALD, EM | 1 |
| MACCABE, HJ | 1 |
| BECROFT, DM | 1 |
| PHILLIPS, LI | 1 |
| EL-TORAEI, I | 1 |
| GABR, MK | 1 |
| EL-SAADANI, AK | 1 |
| SALLAM, F | 1 |
| SAFOUH, M | 1 |
| Hoshikawa, S | 1 |
| Mori, K | 1 |
| Kaise, N | 1 |
| Nakagawa, Y | 1 |
| Ito, S | 1 |
| Yoshida, K | 1 |
| Docter, R | 2 |
| Bos, G | 2 |
| Krenning, EP | 2 |
| Fekkes, D | 1 |
| Visser, TJ | 2 |
| Hennemann, G | 2 |
| Burger, AG | 1 |
| Engler, D | 1 |
| Buergi, U | 1 |
| Weissel, M | 1 |
| Steiger, G | 1 |
| Ingbar, SH | 1 |
| Rosin, RE | 1 |
| Babior, BM | 1 |
| Hershkovitz, E | 1 |
| Leiberman, E | 1 |
| Refetoff, S | 2 |
| Pilpell, D | 1 |
| Phillip, M | 1 |
| LaFranchi, S | 1 |
| Otten, M | 1 |
| van Jaarsveld, PP | 1 |
| Albrecht, CF | 1 |
| Theron, CN | 1 |
| van Zyl, A | 1 |
| Konno, N | 1 |
| Gershengorn, MC | 1 |
| Weintraub, BD | 1 |
| Couch, RM | 1 |
| Dean, HJ | 1 |
| Winter, JS | 1 |
| Hayek, A | 1 |
| Stanbury, JB | 1 |
| Fisher, DA | 1 |
| Strunge, P | 1 |
| Harden, RM | 1 |
| Alexander, WD | 1 |
| Papadopoulos, S | 1 |
| Harrison, MT | 1 |
| Macfarlane, S | 1 |
| Bigozzi, U | 1 |
| Bigazzi, M | 1 |
| Guazzelli, R | 1 |
| Melani, F | 1 |
| Papadopoulos, SN | 1 |
| Vagenakis, AG | 1 |
| Moschos, A | 1 |
| Koutras, DA | 2 |
| Matsaniotis, N | 1 |
| Malamos, B | 2 |
| Bismuth, J | 1 |
| Bechet, MM | 1 |
| Lissitzky, S | 1 |
| Lindeskog, GR | 1 |
| Gustafson, A | 1 |
| Enerbäck, L | 1 |
| Panizon, F | 1 |
| Voss, C | 1 |
| Hartmann, N | 1 |
| Klebanoff, SJ | 2 |
| Green, WL | 1 |
| Rieger, H | 1 |
| Heinonen, OP | 1 |
| Lamberg, BA | 1 |
| Virtamo, J | 1 |
| DeGroot, LJ | 1 |
| Benard, B | 1 |
| DeWind, LT | 1 |
| Hamon, CB | 1 |
| Kitlak, W | 1 |
| Gebert, P | 1 |
| Flock, EV | 1 |
| Bollman, JL | 1 |
| Owen, CA | 1 |
| Zollman, PE | 1 |
| Sfontouris, J | 1 |
| Rigopoulos, G | 1 |
| Rawson, RW | 1 |
| Willgerodt, H | 1 |
| Löbe, J | 1 |
5 reviews available for thyroxine and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Congenital hypothyroidism: etiologies, diagnosis, and management.
Topics: Congenital Hypothyroidism; DNA-Binding Proteins; Female; Forkhead Transcription Factors; Humans; Hyp | 1999 |
The biosynthesis of thyroid hormones.
Topics: Animals; Cattle; Diiodotyrosine; Humans; Iodide Peroxidase; Iodides; Iodine; Metabolism, Inborn Erro | 1976 |
The diagnostic use of radionuclides in the thyroid disorders of childhood.
Topics: Blood Proteins; Child; Diagnosis, Differential; Female; Fetus; Humans; Hypothyroidism; Infant, Newbo | 1971 |
[Physiological significance of iodotyrosine-deiodinases].
Topics: Biopsy; Chemical Phenomena; Chemistry; Chromosomes; Congenital Hypothyroidism; Culture Techniques; D | 1972 |
[Pathogenesis of various forms of arterial hypertension].
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Aging; Aortic Coarctation; Aortic Valve In | 1971 |
31 other studies available for thyroxine and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Proton pump inhibitor treatment for congenital chloride diarrhea.
Topics: Adult; Amniotic Fluid; Betamethasone; Chloride-Bicarbonate Antiporters; Delivery, Obstetric; Diarrhe | 2011 |
THE POSSIBLE OCCURRENCE OF TWO INBORN ERRORS OF IODINE METABOLISM IN ONE PATIENT.
Topics: Adolescent; Child; Congenital Hypothyroidism; Diiodotyrosine; Electrophoresis; Goiter; Humans; Iodid | 1964 |
ABSENT AND DEFECTIVE IODOTYROSINE DEIODINATION IN A FAMILY SOME OF WHOSE MEMBERS ARE GOITROUS CRETINS.
Topics: Adolescent; Congenital Hypothyroidism; Enzymes; Fluids and Secretions; Genetics, Medical; Goiter; Hu | 1965 |
HEREDITARY OROTIC ACIDURIA AND MEGALOBLASTIC ANAEMIA: A SECOND CASE, WITH RESPONSE TO URIDINE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Examination; Child; Fluids and Secret | 1965 |
GOITROUS HYPOTHYROIDISM ASSOCIATED WITH INBORN ERRORS OF THYROXINE METABOLISM.
Topics: Adolescent; Child; Goiter; Humans; Hypothyroidism; Infant; Metabolism, Inborn Errors; Thyroxine | 1965 |
Artifactually elevated serum-free thyroxine levels measured by equilibrium dialysis in a pregnant woman with familial dysalbuminemic hyperthyroxinemia.
Topics: Adult; Amino Acid Substitution; Arginine; Artifacts; Cytosine; Dialysis; Female; Genes, Dominant; Gu | 2004 |
Peripheral resistance to thyroid hormones.
Topics: Humans; Metabolism, Inborn Errors; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Trii | 1984 |
Inherited thyroxine excess: a serum abnormality due to an increased affinity for modified albumin.
Topics: Humans; Immunoelectrophoresis; Metabolism, Inborn Errors; Serum Albumin; Thyroxine; Thyroxine-Bindin | 1981 |
Ether link cleavage is the major pathway of iodothyronine metabolism in the phagocytosing human leukocyte and also occurs in vivo in the rat.
Topics: Amitrole; Animals; Catalase; Chromatography, Gel; Chromatography, Ion Exchange; Diiodotyrosine; Ethe | 1983 |
High prevalence of thyroxine-binding globulin deficiency among Bedouin infants in southern Israel.
Topics: Ethnicity; Humans; Infant, Newborn; Israel; Male; Metabolism, Inborn Errors; Prevalence; Thyrotropin | 1995 |
Raised total thyroxine and free thyroxine index but normal free thyroxine. A serum abnormality due to inherited increased affinity of iodothyronines for serum binding protein.
Topics: Female; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Pedigree; Protein Binding; Serum Album | 1979 |
Serum thyrotropin response to thyrotropin-releasing hormone and free thyroid hormone indices in patients with familiar thyroxine-binding globulin deficiency.
Topics: Adult; Aged; Female; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Serum Globulins; Thyroid | 1976 |
Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH".
Topics: Adolescent; Child; Depression, Chemical; Dexamethasone; Female; Humans; Hyperthyroidism; Metabolism, | 1975 |
Congenital hypothyroidism caused by defective iodide transport.
Topics: Biological Transport, Active; Congenital Hypothyroidism; Female; Humans; Hypothyroidism; Infant; Inf | 1985 |
Advances in the laboratory diagnosis of thyroid disease. II.
Topics: Child; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism; Metabolism, Inborn Errors; Radioimmu | 1973 |
[Familial thyrosine-binding globulin deficiency. A genetic and biochemical assessment of 3 Danish families].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Denmark; Female; Genotype; Humans; Male; Metabolis | 1973 |
The influence of the plasma inorganic iodine concentration on thyroid function in dehalogenase deficiency.
Topics: Adult; Cardiomegaly; Goiter; Humans; Hypothyroidism; Iodine; Iodine Radioisotopes; Male; Metabolism, | 1967 |
[Goiter and hypothyroidism due to a familial defect o deiodation of iodotyrosine].
Topics: Adolescent; Adult; Chromatography; Diiodotyrosine; Female; Goiter; Humans; Hypothyroidism; Metabolis | 1967 |
A case of a partial defect of the iodide trapping mechanism.
Topics: Age Determination by Skeleton; Child; Congenital Hypothyroidism; Diiodotyrosine; Goiter; Humans; Iod | 1970 |
Serum lipoprotein deficiency in diffuse "normolipemic" plane xanthoma.
Topics: Adult; Biopsy; Cholesterol; Chromatography, Thin Layer; Female; Histocytochemistry; Humans; Immunodi | 1972 |
[Diseases due to enzyme defects in childhood. Nosography and recent progress].
Topics: Amino Acid Metabolism, Inborn Errors; Coenzymes; Diet Therapy; Dietary Proteins; Glucose-6-Phosphata | 1971 |
Degradation of thyroid hormones by phagocytosing human leukocytes.
Topics: Ascorbic Acid; Azides; Chromatography, Gel; Chromatography, Paper; Cyanides; Electrophoresis, Paper; | 1973 |
Inherited decrease of the binding capacity of thyroxine-binding globulin (TBG).
Topics: Adolescent; Adult; Albumins; Child; Female; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Pr | 1970 |
Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
Topics: Adolescent; Bone Diseases, Developmental; Child; Deafness; Erythrocytes; Female; Fibroblasts; Goiter | 1972 |
Role of myeloperoxidase-mediated antimicrobial systems in intact leukocytes.
Topics: Anaerobiosis; Azides; Bacteria; Binding Sites; Blood Bactericidal Activity; Candida; Catalase; Chlor | 1972 |
[Clinical and chromosomal studies in a congenital hypothyroidism caused by thyroxin synthesis disorders and middle ear hearing disorders (Pendred- or goiter-deafness syndrome)].
Topics: Adult; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Deafness; Female; Goit | 1968 |
Conjugation of thyroid hormones and analogs by the Gunn rat.
Topics: Animals; Benzoates; Bile; Biliary Fistula; Bilirubin; Chromatography, Paper; Glucosyltransferases; G | 1965 |
Inborn errors of iodine metabolism in Greece.
Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Deafness; Female; Goiter; Greece; Humans; Hypot | 1964 |
Physiological considerations in the management of thyroid cancer.
Topics: 17-Ketosteroids; Adolescent; Adult; Animals; Estradiol; Estrogens; Female; Follow-Up Studies; Goiter | 1965 |
[The need for early treatment of familial inborn errors of iodine metabolism].
Topics: Child; Female; Humans; In Vitro Techniques; Iodine Isotopes; Male; Metabolism, Inborn Errors; Thyroi | 1966 |
Anomalous values for the half-life of radiothyroxine in dyshormonogenetic goiter.
Topics: Adolescent; Adult; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Ma | 1966 |