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thyroxine and Hypotension

thyroxine has been researched along with Hypotension in 30 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Levothyroxine supplementation was identified as an independent variable correlated with an increased incidence of refractory hypotension out of the transitional period; as seen in hypothyroidism with Addison's disease, the immature hypothalamic-pituitary-adrenal axis may not respond properly to the increased demand for cortisol, which may precipitate premature infants into refractory hypotension."7.77Levothyroxine replacement therapy and refractory hypotension out of transitional period in preterm infants. ( Hirose, A; Iwata, O; Iwata, S; Kanda, H; Maeno, Y; Matsuishi, T; Okada, J; Yoshino, M, 2011)
"The aim of this study was to compare the serum AFABP concentrations in hyperthyroid patients and those in euthyroid individuals, and to evaluate the associations between serum AFABP and free thyroxine (fT4) levels."3.81Association Between Serum Levels of Adipocyte Fatty Acid-binding Protein and Free Thyroxine. ( Chen, CL; Chen, PL; Chen, YT; Chi, YC; Shih, SR; Tseng, FY; Wang, CY; Yang, WS, 2015)
"Levothyroxine supplementation was identified as an independent variable correlated with an increased incidence of refractory hypotension out of the transitional period; as seen in hypothyroidism with Addison's disease, the immature hypothalamic-pituitary-adrenal axis may not respond properly to the increased demand for cortisol, which may precipitate premature infants into refractory hypotension."3.77Levothyroxine replacement therapy and refractory hypotension out of transitional period in preterm infants. ( Hirose, A; Iwata, O; Iwata, S; Kanda, H; Maeno, Y; Matsuishi, T; Okada, J; Yoshino, M, 2011)
" Type 1 diabetes mellitus had been diagnosed when he was 13 years old, hypothyroidism was treated with L-thyroxine for 2 years."3.72[Prerenal kidney failure in type 1 diabetes mellitus]. ( Hübinger, A; Scherbaum, WA; Schloot, NC, 2003)
" Resting heart rate, body weight, colonic temperature and serum thyroxine (T4) were significantly lower in the treated hypothyroid rats than in the controls."3.67A time-course study of hypothyroidism-induced hypotension: its relation to hypothermia. ( Lum, L; Thompson, EB, 1986)
"Hypothyroidism is associated with abnormalities in lipid metabolism but its effect on LDL size is not known."2.69Low-density lipoprotein size in primary hypothyroidism. Effects of hormone replacement therapy. ( Lupattelli, G; Mannarino, E; Pagliaricci, S; Pirro, M; Roscini, AR; Siepi, D, 1999)
"Myxedema coma is the term given to the most severe presentation of profound hypothyroidism and is often fatal in spite of therapy."2.43Myxedema coma. ( Wartofsky, L, 2006)
"Myxoedema coma is a rare emergency needing prompt recognition and urgent treatment before diagnostic confirmation."2.36Myxoedema coma. A review. ( Khaleeli, A, 1978)
"A 31-year-old lady, diagnosed to have premature ovarian failure in the gynecology clinic, was referred for endocrine assessment because of an abnormal thyroid function test."1.46Premature ovarian failure could be an alarming sign of polyglandular autoimmune dysfunction. ( Assem, M; Saif, A, 2017)
"Myxoedema coma is a rare, reversible condition with a high mortality and should be considered as a differential diagnosis in medical emergencies."1.42Complete recovery after severe myxoedema coma complicated by status epilepticus. ( Fjølner, J; Kampmann, U; Nielsen, S; Søndergaard, E, 2015)
"Lower trauma admission T4 levels were associated with the need for greater crystalloid resuscitation within the first 24 h."1.39Altered thyroid function in severely injured patients. ( Collins, H; Grill, E; Pascual, J; Sarani, B; Sims, CA; Sonnad, SS; Strong, M, 2013)
"Primary adrenal insufficiency is a chronic, debilitating condition that usually produces a variety of characteristic but non-specific clinical features."1.29Adrenal crisis in active duty service members. ( Asp, AA; Georgitis, WJ; McDermott, MT, 1996)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199011 (36.67)18.7374
1990's4 (13.33)18.2507
2000's7 (23.33)29.6817
2010's8 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saif, A1
Assem, M1
Kumar, E1
McCurdy, MT1
Koch, CA1
Hamadah, A1
Fülöp, T1
Gharaibeh, KA1
Fjølner, J1
Søndergaard, E1
Kampmann, U1
Nielsen, S1
Tseng, FY1
Chen, PL1
Chen, YT1
Chi, YC1
Shih, SR1
Wang, CY1
Chen, CL1
Yang, WS1
Spyridoulias, A1
Riaz, MS1
González Castro, AM1
López Piñeiro, S1
Moreno López, E1
Rodríguez Losada, M1
Okada, J1
Iwata, S1
Hirose, A1
Kanda, H1
Yoshino, M1
Maeno, Y1
Matsuishi, T1
Iwata, O1
Grill, E1
Strong, M1
Sonnad, SS1
Sarani, B1
Pascual, J1
Collins, H1
Sims, CA1
Gharabaghi, MA2
Behdadnia, A1
Abtahi, H1
OSORIO, JA2
Schloot, NC1
Hübinger, A1
Scherbaum, WA1
Morricone, L1
Malavazos, AE1
Cereda, E1
Donati, C1
Ambrosi, B1
Wartofsky, L1
Filippi, L1
Pezzati, M1
Poggi, C1
Rossi, S1
Cecchi, A1
Santoro, C1
de Jong, W1
de Wied, D1
Fallon, JJ1
Yelovich, RM1
Green, PJ1
McDermott, MT1
Georgitis, WJ1
Asp, AA1
Cummings, JF1
Davies, R1
Newton, RW1
Thompson, CJ1
Roscini, AR1
Lupattelli, G1
Siepi, D1
Pagliaricci, S1
Pirro, M1
Mannarino, E1
Zajaczkowska, M1
Kołłataj, W1
Kołłataj, B1
Borzecka, H1
Szewczyk, L1
Buriak, VN1
Khaleeli, A1
Gupta, R1
Sinha, J1
Purohit, R1
Baksi, SN1
Thompson, EB1
Lum, L1
Levelle, JP1
Jopling, MW1
Sklar, GS1
Cornu, P1
Bickert, P1
Segrestaa, JM1
Marsan, C1
Ertel, M1
Manicacci, M1
Laffay, J1
Lamotte, M1
Newmark, SR1
Himathongkam, T1
Shane, JM1
Blum, M1
Lutomirsky, C1

Reviews

3 reviews available for thyroxine and Hypotension

ArticleYear
Myxedema coma.
    Endocrinology and metabolism clinics of North America, 2006, Volume: 35, Issue:4

    Topics: Aged; Coma; Female; Glucocorticoids; Humans; Hyponatremia; Hypotension; Hypothermia; Male; Myxedema;

2006
Myxoedema coma. A review.
    Pahlavi medical journal, 1978, Volume: 9, Issue:2

    Topics: Acute Kidney Injury; Coma; Diagnosis, Differential; Hemorrhage; Humans; Hypoglycemia; Hyponatremia;

1978
Myxedema coma.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:6

    Topics: Adrenal Glands; Cachexia; Central Nervous System; Coma; Heart Diseases; Humans; Hypoglycemia; Hypona

1972

Trials

2 trials available for thyroxine and Hypotension

ArticleYear
Dopamine versus dobutamine in very low birthweight infants: endocrine effects.
    Archives of disease in childhood. Fetal and neonatal edition, 2007, Volume: 92, Issue:5

    Topics: Blood Pressure; Cardiotonic Agents; Dobutamine; Dopamine; Female; Heart Rate; Human Growth Hormone;

2007
Low-density lipoprotein size in primary hypothyroidism. Effects of hormone replacement therapy.
    Annals of nutrition & metabolism, 1999, Volume: 43, Issue:6

    Topics: Electrophoresis, Polyacrylamide Gel; Female; Hormone Replacement Therapy; Humans; Hypotension; Hypot

1999

Other Studies

25 other studies available for thyroxine and Hypotension

ArticleYear
Premature ovarian failure could be an alarming sign of polyglandular autoimmune dysfunction.
    Endocrine regulations, 2017, Apr-25, Volume: 51, Issue:2

    Topics: Addison Disease; Adult; Candidiasis, Chronic Mucocutaneous; Female; Fludrocortisone; Glucocorticoids

2017
Impairment of Thyroid Function in Critically Ill Patients in the Intensive Care Units.
    The American journal of the medical sciences, 2018, Volume: 355, Issue:3

    Topics: Aged; Critical Illness; Female; Humans; Hypotension; Hypothyroidism; Intensive Care Units; Male; Mid

2018
Complete recovery after severe myxoedema coma complicated by status epilepticus.
    BMJ case reports, 2015, Mar-25, Volume: 2015

    Topics: Aged; Coma; Critical Care; Female; Glasgow Coma Scale; Humans; Hypotension; Hypothermia; Myxedema; S

2015
Association Between Serum Levels of Adipocyte Fatty Acid-binding Protein and Free Thyroxine.
    Medicine, 2015, Volume: 94, Issue:41

    Topics: Adipocytes; Adult; Fatty Acid-Binding Proteins; Female; Humans; Hyperthyroidism; Hypotension; Male;

2015
Myxoedema coma in the setting of hyperglycaemic hyperosmolar state.
    BMJ case reports, 2016, Jan-11, Volume: 2016

    Topics: Female; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Hypoglycemic Agents; Hypotension; Hypoth

2016
[Myxedematous coma in a case of emergency herniorrhaphy].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:5

    Topics: Aged, 80 and over; Bradycardia; Coma; Comorbidity; Emergencies; Epilepsy, Generalized; Female; Herni

2009
Levothyroxine replacement therapy and refractory hypotension out of transitional period in preterm infants.
    Clinical endocrinology, 2011, Volume: 74, Issue:3

    Topics: Age of Onset; Female; Gestational Age; Humans; Hypotension; Incidence; Infant; Infant, Newborn; Infa

2011
Altered thyroid function in severely injured patients.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Adolescent; Adult; Erythrocyte Transfusion; Female; Humans; Hypotension; Male; Middle Aged; Prospect

2013
Hypoadrenal syndrome in a patient with amyloidosis secondary to familial Mediterranean fever.
    BMJ case reports, 2013, Jan-29, Volume: 2013

    Topics: Adrenal Insufficiency; Adult; Amyloidosis; Anti-Inflammatory Agents; Diarrhea; Familial Mediterranea

2013
Influence of the thyroid hormone on the reactivity to vasoactive substances in the rat.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Humans; Hypertension; Hypotension; Thyroxine

1956
Influence of the thyroid hormone on the reactivity to vasoactive substances in the rat.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Humans; Hypertension; Hypotension; Thyroxine

1956
Influence of the thyroid hormone on the reactivity to vasoactive substances in the rat.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Humans; Hypertension; Hypotension; Thyroxine

1956
Influence of the thyroid hormone on the reactivity to vasoactive substances in the rat.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Humans; Hypertension; Hypotension; Thyroxine

1956
[Prerenal kidney failure in type 1 diabetes mellitus].
    Deutsche medizinische Wochenschrift (1946), 2003, Dec-05, Volume: 128, Issue:49

    Topics: Addison Disease; Adult; Anti-Inflammatory Agents; Diabetes Mellitus, Type 1; Diagnosis, Differential

2003
L-Thyroxine suppressive therapy and autonomic nervous system control in patients with thyroid disease.
    Hormone research, 2006, Volume: 65, Issue:4

    Topics: Autonomic Nervous System; Cough; Dose-Response Relationship, Drug; Female; Goiter, Nodular; Heart Ra

2006
Independence of the thyroid and adrenal gland in potassium thiocyanate (KCNS) induced hypotension in rats.
    Acta endocrinologica, 1966, Volume: 53, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Dexamethasone; Hypophysectomy; Hypotension;

1966
Euthyroid sick syndrome. Association with urosepsis in an elderly man.
    Postgraduate medicine, 1984, May-15, Volume: 75, Issue:7

    Topics: Aged; Dopamine; Humans; Hypotension; Hypothyroidism; Male; Proteus Infections; Proteus mirabilis; Se

1984
Adrenal crisis in active duty service members.
    Military medicine, 1996, Volume: 161, Issue:10

    Topics: Acute Disease; Addison Disease; Adult; Diagnostic Errors; Humans; Hydrocortisone; Hypotension; Male;

1996
Hypopituitarism following coronary artery bypass surgery.
    Scottish medical journal, 1997, Volume: 42, Issue:4

    Topics: Aged; Angina Pectoris; Coronary Artery Bypass; Drug Therapy, Combination; Glucocorticoids; Humans; H

1997
[Hypothyroidism as the cause of lowered blood pressure during hemodialysis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2001, Volume: 10, Issue:58

    Topics: Adult; Female; Humans; Hypotension; Hypothyroidism; Renal Dialysis; Thyroxine; Uremia

2001
[Characteristics of the thyroid system in adolescents with the autonomic and vascular disfunction of the hypotensive type].
    Likars'ka sprava, 2000, Issue:6

    Topics: Adolescent; Autonomic Nervous System Diseases; Child; Female; Humans; Hypotension; Male; Thyroid Gla

2000
Refractory hypotension. A clue to myxedema coma.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Coma; Emergencies; Female; Humans; Hypotension; Myxedema; Shock; Thy

1992
Hypotensive action of parathyroid hormone in hypoparathyroid and hyperparathyroid rats.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 1

    Topics: Animals; Blood Pressure; Calcium; Calcium Carbonate; Disease Models, Animal; Femur; Hyperparathyroid

1988
A time-course study of hypothyroidism-induced hypotension: its relation to hypothermia.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Heart Rate; Hypotension; Hypothermia; Hypothyroidism; Male; Pr

1986
Perioperative hypothyroidism: an unusual postanesthetic diagnosis.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Anesthesia, General; Female; Hip Fractures; Humans; Hypotension; Hypothyroidism; Intraoperative Comp

1985
[Myxedema coma. Study of 3 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Apr-26, Volume: 49, Issue:20

    Topics: Adrenal Insufficiency; Aged; Coma; Female; Hematologic Diseases; Humans; Hyponatremia; Hypotension;

1973
Myxedema coma.
    JAMA, 1974, Nov-11, Volume: 230, Issue:6

    Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Aged; Coma; Emergencies; Humans; Hyponat

1974
[Pathophysiological mechanisms in hypotension caused by endocrine disorders].
    Praxis, 1969, Jun-24, Volume: 58, Issue:25

    Topics: Adrenal Cortex Hormones; Adult; Catecholamines; Endocrine System Diseases; Humans; Hypotension; Midd

1969