Page last updated: 2024-11-06

thyroxine and Hypertrophy, Left Ventricular

thyroxine has been researched along with Hypertrophy, Left Ventricular in 16 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
"On echocardiography, the left ventricular hypertrophy, identified earlier, shoed partial regression."1.91Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism. ( Chae, Y; Kang, BT; Kim, H; Koo, Y; Lee, D; Lee, H; Park, J; Yang, MP; Yun, T, 2023)
"Pravastatin treatment led to inhibition of Rac-GTPase activity and integrin signaling."1.37Cardiac remodeling caused by transgenic overexpression of a corn Rac gene. ( Abouelnaga, ZA; Alhaj, MA; Awad, MM; Citro, LA; El-Sayed, O; Elnakish, MT; Hassanain, HH; Hassona, MD; Khan, M; Kulkarni, A; Kuppusamy, P; Moldovan, L; Sayyid, M, 2011)
"The ventricular remodeling of mice were induced by subcutaneous injection of ISO with the dosage of 2 mg/kg daily for 7 d and the rats with L-Thy intraperitoneally with the dosage of 0."1.36[Effect of Chrysanthemum indicum on ventricular remodeling in rats]. ( Chen, CX; Gao, JP; Gu, WL; Lv, J; Wan, Y; Wu, Q, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (37.50)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Lee, H1
Lee, D1
Park, J1
Yun, T1
Koo, Y1
Chae, Y1
Kang, BT1
Yang, MP1
Kim, H1
Badi, R1
Teixeira, RB1
Zimmer, A1
de Castro, AL1
Carraro, CC1
Casali, KR1
Dias, IGM1
Godoy, AEG1
Litvin, IE1
Belló-Klein, A1
da Rosa Araujo, AS1
Karavelioglu, Y1
Baran, A1
Karapinar, H1
Küçükdurmaz, Z1
Yilmaz, A1
Wu, Q1
Chen, CX1
Gu, WL1
Gao, JP1
Wan, Y1
Lv, J1
Elnakish, MT1
Awad, MM1
Hassona, MD1
Alhaj, MA1
Kulkarni, A1
Citro, LA1
Sayyid, M1
Abouelnaga, ZA1
El-Sayed, O1
Kuppusamy, P1
Moldovan, L1
Khan, M1
Hassanain, HH1
Matuszewska, G1
Roskosz, J1
Włoch, J1
Jurecka-Tuleja, B1
Hasse-Lazar, K1
Kowalczyk, P1
Jarzab, B1
Mark, PB1
Watkins, S1
Dargie, HJ1
Fernandes, ML1
Ferro, EA1
Beletti, ME1
Resende, ES1
Song, LJ1
Wang, GL1
Liu, J1
Qiu, QY1
Ou, JH1
Guan, YY1
Robert, V1
Silvestre, JS1
Charlemagne, D1
Sabri, A1
Trouvé, P1
Wassef, M1
Swynghedauw, B2
Delcayre, C1
Biondi, B1
Fazio, S1
Carella, C1
Amato, G1
Cittadini, A1
Lupoli, G1
Saccà, L1
Bellastella, A1
Lombardi, G1
Moalic, JM1
Bourgeois, F1
Mansier, P1
Machida, CA1
Carré, F1
Chevalier, B1
Pitarque, P1
Tomanek, RJ2
Butters, CA1
Zimmerman, MB1
Chang, KC1
Figueredo, VM1
Schreur, JH1
Kariya, K1
Weiner, MW1
Simpson, PC1
Camacho, SA1
Doty, MK1
Sandra, A1

Trials

1 trial available for thyroxine and Hypertrophy, Left Ventricular

ArticleYear
[Evaluation of effects of L-thyroxine therapy in differentiated thyroid carcinoma on the cardiovascular system --prospective study].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2001, Volume: 54 Suppl 1

    Topics: Female; Humans; Hypertrophy, Left Ventricular; Iodine Radioisotopes; Male; Middle Aged; Prospective

2001

Other Studies

15 other studies available for thyroxine and Hypertrophy, Left Ventricular

ArticleYear
Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism.
    Acta veterinaria Hungarica, 2023, 10-17, Volume: 71, Issue:2

    Topics: Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cat Diseases; Cats; Furosemide; Heart Failure;

2023
Acylated Ghrelin Attenuates l-Thyroxin-induced Cardiac Damage in Rats by Antioxidant and Anti-inflammatory Effects and Downregulating Components of the Cardiac Renin-angiotensin System.
    Journal of cardiovascular pharmacology, 2021, 09-01, Volume: 78, Issue:3

    Topics: Acylation; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Ghrelin; Hyperth

2021
Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats.
    Life sciences, 2018, Mar-01, Volume: 196

    Topics: Animals; Echocardiography; Exercise Therapy; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardi

2018
Reversible cardiomyopathy associated with autoimmune polyendocrine syndrome type II.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:9

    Topics: Adult; Cardiomyopathies; Delayed Diagnosis; Female; Fludrocortisone; Hormone Replacement Therapy; Hu

2013
[Effect of Chrysanthemum indicum on ventricular remodeling in rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Chrysanthemum; Disease Models, Animal; Drugs, Chinese Herbal;

2010
Cardiac remodeling caused by transgenic overexpression of a corn Rac gene.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Aging; Amino Acid Sequence; Analysis of Variance; Animals; Echocardiography; Genotype; Hypertrophy,

2011
Cardiomyopathy induced by performance enhancing drugs in a competitive bodybuilder.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:7

    Topics: Adult; Anabolic Agents; Doping in Sports; Ephedrine; Growth Hormone; Humans; Hypertrophy, Left Ventr

2005
Spironolactone effects on myocardium changes induced by thyroid hormone in rats.
    Arquivos brasileiros de cardiologia, 2007, Volume: 89, Issue:6

    Topics: Analysis of Variance; Animals; Body Weight; Heart; Heart Rate; Hypertrophy, Left Ventricular; Male;

2007
Cellular mechanisms of reduced sarcoplasmic reticulum Ca2+ content in L-thyroxin induced rat ventricular hypertrophy.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:4

    Topics: Animals; Caffeine; Calcium; Cardiomegaly; Electrocardiography; Heart Ventricles; Hypertrophy, Left V

2008
Biological determinants of aldosterone-induced cardiac fibrosis in rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1

    Topics: Aldosterone; Animals; Blotting, Northern; Collagen; Fibrosis; Heart; Histocytochemistry; Hypertensio

1995
Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Echocardiography; Electrocardiography; El

1993
Beta 1 adrenergic receptor and G alpha s mRNAs in rat heart as a function of mechanical load and thyroxine intoxication.
    Cardiovascular research, 1993, Volume: 27, Issue:2

    Topics: Animals; Blotting, Northern; GTP-Binding Proteins; Hypertrophy, Left Ventricular; Male; Myocardium;

1993
Initiation of cardiac hypertrophy in response to thyroxine is not limited by age.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Aging; Animals; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Heart; Hemodynamics;

1993
Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts.
    The Journal of clinical investigation, 1997, Oct-01, Volume: 100, Issue:7

    Topics: Animals; Aorta; Aortic Valve Stenosis; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPas

1997
Early coronary angiogenesis in response to thyroxine: growth characteristics and upregulation of basic fibroblast growth factor.
    Circulation research, 1998, Mar-23, Volume: 82, Issue:5

    Topics: Animals; Capillaries; Coronary Vessels; Fibroblast Growth Factor 2; Gene Expression; Hypertrophy, Le

1998