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thyroxine and Hyperplasia

thyroxine has been researched along with Hyperplasia in 122 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia."7.85Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption. ( Romanelli, F; Sansone, A; Sansone, M; Tedone, R; Vena, W, 2017)
" Administration of the mAbs KSAb1 (IgG2b) or KSAb2 (IgG2a), which have similar stimulating properties but different TSH-binding blocking activity, resulted in significantly elevated serum thyroxine (T(4)) levels and thyroid hyperplasia."7.74Chronic exposure in vivo to thyrotropin receptor stimulating monoclonal antibodies sustains high thyroxine levels and thyroid hyperplasia in thyroid autoimmunity-prone HLA-DRB1*0301 transgenic mice. ( Banga, JP; David, CS; Flynn, JC; Gilbert, JA; Kong, YC; Meroueh, C; Snower, DP, 2007)
"We prospectively evaluated the effects of 12 months thyrotropin suppressive levo-thyroxine (L-T4) therapy in terms of changes in both thyroid nodule size and cytological features and considered whether thyroid nodule size changes actually resulted in (or were the result of) cytological changes."7.72Changes in both size and cytological features of thyroid nodule after levothyroxine treatment. ( Castagna, MG; Finocchiaro, MD; Lo Presti, VP; Mandolfino, M; Mattina, F; Moleti, M; Trimarchi, F; Vermiglio, F; Violi, MA; Zimbaro, G, 2003)
"Pituitary hyperplasia consequent to untreated primary hypothyroidism undergoes impressive regression following thyroxine therapy."7.70Residual pituitary enlargement in primary hypothyroidism despite 1 1/2 years of L-thyroxine therapy. ( Goswami, R; Kochupillai, N; Sharma, R; Tandon, N, 1999)
"Thirty-three thyroid specimens obtained from 28 patients with clinically and laboratory-proven iodine-induced hypothyroidism were examined clinically, histologically, immunohistochemically, and ultrastructurally."7.68Iodine-induced hypothyroidism: a clinical and histological study of 28 patients. ( Hashimoto, T; Matsubara, F; Michigishi, T; Mizukami, Y; Nonomura, A; Takazakura, E; Tonami, N, 1993)
"Involution of thyroid hyperplasia was induced in mice by discontinuing a goitrogenic treatment (low iodine diet plus 0."7.67Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution. ( Beckers, C; Cornette, C; Denef, JF; Haumont, S; Many, MC; van den Hove-Vandenbroucke, MF, 1985)
"Thyrotroph cell hyperplasia in primary hypothyroidism though well described is often not discussed as it remains clinically silent."5.32Reversibility of thyrotroph hyperplasia after L-thyroxine replacement therapy in patients with juvenile primary hypothyroidism. ( Bhansali, A; Khandelwal, N; Masoodi, SR; Sreenivasulu, P, 2004)
" The intrathyroidal iodine deficiency itself and the increased activity of local growth factors, however, may be the main causes of initiation, promotion and maintenance of hyperplasia."4.79Thyroxine treatment of benign goiter. ( Gärtner, R, 1994)
" At 24 weeks she developed facial palsy and pituitary hyperplasia which responded to a combination of steroids and thyroxine."3.96Neurological manifestation in severe hypothyroidism in pregnancy. ( Dadhwal, V; Noor, N; Sharma, A, 2020)
"We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia."3.85Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption. ( Romanelli, F; Sansone, A; Sansone, M; Tedone, R; Vena, W, 2017)
"Thyroxine substitution therapy was the first choice of pituitary tumorous hyperplasia due to primary hypothyroidism."3.78Pituitary tumorous hyperplasia due to primary hypothyroidism. ( Han, L; Lei, T; Shu, K; Wang, J, 2012)
" Thyroxine substitution therapy appears to be effective for primary hypothyroidism secondary to pituitary hyperplasia."3.76[Pituitary hyperplasia secondary to primary hypothyroidism in children: report of 8 cases]. ( Li, T; Xu, AJ, 2010)
" Administration of the mAbs KSAb1 (IgG2b) or KSAb2 (IgG2a), which have similar stimulating properties but different TSH-binding blocking activity, resulted in significantly elevated serum thyroxine (T(4)) levels and thyroid hyperplasia."3.74Chronic exposure in vivo to thyrotropin receptor stimulating monoclonal antibodies sustains high thyroxine levels and thyroid hyperplasia in thyroid autoimmunity-prone HLA-DRB1*0301 transgenic mice. ( Banga, JP; David, CS; Flynn, JC; Gilbert, JA; Kong, YC; Meroueh, C; Snower, DP, 2007)
" Phenobarbital caused follicular cell hypertrophy and hyperplasia in the thyroid and centrilobular hypertrophy in the liver, without effects on serum triiodotyronine (T(3)), thyroxine (T(4)) levels."3.74Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats. ( Coelho-Palermo Cunha, G; van Ravenzwaay, B, 2007)
"Euthyroid (as defined by total thyroxine) senior cats with low TSH are likely to have histological evidence of nodular thyroid disease, and such cats could be considered to be subclinically hyperthyroid."3.74Subclinical hyperthyroidism in cats: a spontaneous model of subclinical toxic nodular goiter in humans? ( Elliott, J; Kirkby, R; Scase, T; Smith, K; Syme, H; Wakeling, J, 2007)
"We prospectively evaluated the effects of 12 months thyrotropin suppressive levo-thyroxine (L-T4) therapy in terms of changes in both thyroid nodule size and cytological features and considered whether thyroid nodule size changes actually resulted in (or were the result of) cytological changes."3.72Changes in both size and cytological features of thyroid nodule after levothyroxine treatment. ( Castagna, MG; Finocchiaro, MD; Lo Presti, VP; Mandolfino, M; Mattina, F; Moleti, M; Trimarchi, F; Vermiglio, F; Violi, MA; Zimbaro, G, 2003)
"To assess the involvement of cellular inhibition and the appearance of apoptosis in regression of the hyperplastic thyroid gland towards normality, an experimental design was used to elicit non-toxic goiter by inducing hyperplastic goiter in rats by treatment with methimazole."3.70Cell proliferation and apoptosis of thyroid follicular cells are involved in the involution of experimental non-tumoral hyperplastic goiter. ( Blanco, EJ; Carretero, J; Juanes, JA; Riesco, JM; Riesco-Lopez, JM; Vázquez, G; Vázquez, R, 1998)
"Pituitary hyperplasia consequent to untreated primary hypothyroidism undergoes impressive regression following thyroxine therapy."3.70Residual pituitary enlargement in primary hypothyroidism despite 1 1/2 years of L-thyroxine therapy. ( Goswami, R; Kochupillai, N; Sharma, R; Tandon, N, 1999)
"Thirty-three thyroid specimens obtained from 28 patients with clinically and laboratory-proven iodine-induced hypothyroidism were examined clinically, histologically, immunohistochemically, and ultrastructurally."3.68Iodine-induced hypothyroidism: a clinical and histological study of 28 patients. ( Hashimoto, T; Matsubara, F; Michigishi, T; Mizukami, Y; Nonomura, A; Takazakura, E; Tonami, N, 1993)
"204 patients with a single or dominant 'cold' thyroid nodule were treated with l-thyroxine, 150-250 micrograms/d, for 4 to 12 months."3.68The outcome of benign thyroid nodules correlates with the findings of fine needle biopsy. ( Katsouyanni, K; Kitsopanides, J; Koutras, DA; Tseleni-Balafouta, S, 1991)
"Involution of thyroid hyperplasia was induced in mice by discontinuing a goitrogenic treatment (low iodine diet plus 0."3.67Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution. ( Beckers, C; Cornette, C; Denef, JF; Haumont, S; Many, MC; van den Hove-Vandenbroucke, MF, 1985)
"Five female patients with primary hypothyroidism and radiological evidence of a pituitary enlargement were studied before and after a mean of 30 months (range 12-83 months) treatment with thyroxine (T4)."3.67Pituitary gland enlargement in primary hypothyroidism: a report of 5 cases with follow-up data. ( Ahmed, M; Banna, M; Sakati, N; Woodhouse, N, 1989)
"Sellar enlargement and suprasellar extension of a pituitary mass, demonstrated by magnetic resonance imaging or computed tomographic scanning in three children with primary hypothyroidism, resolved after treatment with levothyroxine sodium."3.67Reversible suprasellar pituitary mass secondary to hypothyroidism. ( Albright, AL; Atchison, JA; Lee, PA, 1989)
"Pituitary hyperplasia secondary to primary hypothyroidism has been reported in the literature in both adults and children."2.43Pituitary hyperplasia secondary to primary hypothyroidism: a case report and review of the literature. ( Joshi, AS; Woolf, PD, 2005)
" Time-course and dose-response experiments for free- and total thyroxine (T4) and triiodothyronine (T3) plasma levels for thyroid-stimulating hormone (TSH) and thyroid gland histomorphology were determined in male Wistar rats."1.43Irreversible thyroid disruption induced after subchronic exposure to hexachlorobenzene in male rats. ( Chalouati, H; Gamet-Payrastre, L; Saad, MB, 2016)
"She had precocious puberty, pituitary hyperplasia and multiple cystic ovaries in addition to clinical signs of severe congenital hypothyroidism."1.43[Van Wyk-Grumbach syndrome: A case report and 
literature review]. ( Jin, P; Mo, Z; Xie, Y; Yang, F; Zhang, Q, 2016)
"Pituitary hyperplasia due to primary hypothyroidism was diagnosed on the basis of clinical manifestations, endocrine examination and MRI."1.36Pituitary hyperplasia in children with short stature and primary hypothyroidism. ( Aijing, X; Tang, L, 2010)
" Groups of five male and five female Fischer rats and B6C3F1 mice were administered 2MI by dosed feed at 0, 1,200, 3,300, or 10,000 ppm or 4MI at 0, 300, 800, or 2,500 ppm for 15 days, and groups of 10 male and 10 female Fischer rats and B6C3F1 mice were administered 2MI or 4MI at 0, 625, 1,250, 2,500, 5,000 or 10,000 ppm for 14 weeks."1.33Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. ( Chan, P; Mahler, J; Nyska, A; Travlos, G; Wenk, M, 2006)
"In conclusion, these data indicate that thyroid neoplasms observed in the nelfinavir-treated rats were secondary to thyroid hormone imbalance."1.33Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia. ( Burns-Naas, LA; Capen, CC; Chen, M; Cook, JC; Evering, W; Furman, G; Gasser, R; Ivett, JL; Jessen, B; McClain, RM; Ryan, TE; Shetty, B; Stevens, G; Theiss, JC; Webber, S; Wu, E; Zorbas, M, 2005)
"Thyrotroph cell hyperplasia in primary hypothyroidism though well described is often not discussed as it remains clinically silent."1.32Reversibility of thyrotroph hyperplasia after L-thyroxine replacement therapy in patients with juvenile primary hypothyroidism. ( Bhansali, A; Khandelwal, N; Masoodi, SR; Sreenivasulu, P, 2004)
"Body weights were unaffected by PCN treatment, but were reduced 21% after 19 weeks of PCB treatment compared to control."1.32Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB). ( Habeebu, SM; Klaassen, CD; Muppidi, JR; Vansell, NR, 2004)
"A 41-year-old male with primary hypothyroidism and a huge TSH-secreting pituitary tumor presented with a bleeding nasal mass that was initially misdiagnosed as a paraganglioma."1.30Primary hypothyroidism-associated TSH-secreting pituitary adenoma/hyperplasia presenting as a bleeding nasal mass and extremely elevated TSH level. ( Bakheet, SM; Ghannam, NN; Hammami, MM; Muttair, Z, 1999)
" injection) were examined following chronic administration of 0."1.29Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors. ( Hayashi, Y; Kitaura, K; Mitsumori, K; Onodera, H; Shimo, T; Takahashi, M; Yasuhara, K, 1995)
"A 12-year-old girl presented with primary hypothyroidism, secondary pituitary hyperplasia, and intracranial hypertension."1.29Primary hypothyroidism with intracranial hypertension and pituitary hyperplasia. ( Adams, C; Dean, HJ; Fewer, DH; Israels, SJ; Patton, A, 1994)
"In both patients the hyperprolactinaemia was relatively mild and menorrhagia had been present for many years."1.28Pituitary enlargement and hyperprolactinaemia due to primary hypothyroidism: errors and delays in diagnosis. ( Chan, AW; Foy, PM; MacFarlane, IA; Miles, JB, 1990)
"Hyperprolactinemia with secondary hypothyroidism, caused by a pituitary adenoma, must be distinguished from primary hypothyroidism, also a cause of hyperprolactinemia."1.28[Primary hypothyroidism presenting with amenorrhea, galactorrhea, hyperprolactinemia and enlarged pituitary]. ( Barr, I; Diamant, YZ; Tadmor, OP, 1992)
"A 63-year-old man with a goiter and primary hypothyroidism due to Hashimoto's thyroiditis was found to have hypercalcitonemia and, though hypothyroid, markedly elevated serum total and free T3 levels."1.28C-cell hyperplasia of the thyroid in a patient with goitrous hypothyroidism and Hashimoto's thyroiditis. ( Libbey, NP; Nowakowski, KJ; Tucci, JR, 1989)
"Two patients with persistent lymphocytic thyroiditis and thyrotoxicosis were studied."1.27Immunologic studies in two patients with persistent lymphocytic thyroiditis, thyrotoxicosis, and low radioactive iodine uptake. ( Elliot, I; Gupta, M; Hostetter, A; Sheeler, L; Skillern, P; Tubbs, R, 1984)
"The incidence of thyroid adenomas and cancers was 20% (4/20) and 10% (2/20) in rats treated with DHPN alone."1.27Effects of castration before and after treatment with N-bis (2-hydroxypropyl)-nitrosamine (DHPN) on the development of thyroid tumors in rats treated with DHPN followed by phenobarbital. ( Hashimoto, H; Hiasa, Y; Katoh, Y; Kitahori, Y; Konishi, N; Minami, S; Murata, Y; Ohshima, M; Sakaguchi, Y; Shimoyama, T, 1987)
" The reduction in serum T4 levels was established from the earliest time point (2 weeks) throughout the whole dosing period (18-23 weeks)."1.27Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys. ( Brouwer, A; van den Berg, KJ; Zurcher, C, 1988)
" On Day 15, all rats were dosed iv with [125I]thyroxine (33 microCi/rat)."1.27Thyroid and liver trophic changes in rats secondary to liver microsomal enzyme induction caused by an experimental leukotriene antagonist (L-649,923). ( Bracht, LJ; Eigenberg, DA; Sanders, JE; van Zwieten, MJ; Wang, WR, 1988)
"A 34-year-old woman with longstanding untreated thyroprivic hypothyroidism and pituitary enlargement is reported here in whom visual failure coincided with thyroid hormone replacement."1.26Visual failure during replacement therapy in primary hypothyroidism with pituitary enlargement. ( Breidahl, HD; Essex, WB; Murray, RM; Stockigt, JR; West, RH, 1976)

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-199043 (35.25)18.7374
1990's30 (24.59)18.2507
2000's26 (21.31)29.6817
2010's19 (15.57)24.3611
2020's4 (3.28)2.80

Authors

AuthorsStudies
Ms, AG1
Shekhawat, VS1
Chander, A1
Shimazaki, S1
Sato, J1
Sharma, A1
Noor, N1
Dadhwal, V1
Bellelli, R1
Vitagliano, D1
Federico, G1
Marotta, P1
Tamburrino, A1
Salerno, P1
Paciello, O1
Papparella, S1
Knauf, JA1
Fagin, JA1
Refetoff, S1
Troncone, G1
Santoro, M1
Sansone, A1
Sansone, M1
Vena, W1
Tedone, R1
Romanelli, F1
Nachawi, N1
Bodnar, TW1
Cao, J1
Lei, T2
Chen, F1
Zhang, C1
Ma, C1
Huang, H1
Hu, Y1
Wang, Q1
Li, G1
Sun, X1
Liu, C1
Johnston, PC1
Ellis, PK1
Hunter, SJ1
Chalouati, H1
Gamet-Payrastre, L1
Saad, MB1
Hill, KE1
Shaw, IC1
Gaspari, L1
Paris, F1
Leboucq, N1
Bonafé, A1
Sultan, C1
Kayes, TD1
Weisman, GA1
Camden, JM1
Woods, LT1
Bredehoeft, C1
Downey, EF1
Cole, J1
Braley-Mullen, H1
Jin, P1
Zhang, Q1
Mo, Z1
Yang, F1
Xie, Y1
Alley, MR1
Twentyman, CM1
Sancha, SE1
Clark, P1
Maloney, RF1
Marshall, B1
Chernoff, K1
Saenger, P1
Mytinger, JR1
Blackman, JA1
Goodkin, HP1
Kit, B1
Franceschini, B1
Lee, CY1
Hsu, HH1
Lai, HY1
Lee, ST1
Wang, Y1
Zhang, S1
Cheng, W1
Zeng, T1
Grim, KC1
Wolfe, M1
Braunbeck, T1
Iguchi, T1
Ohta, Y1
Tooi, O1
Touart, L1
Wolf, DC1
Tietge, J1
Xu, AJ1
Li, T1
Aijing, X1
Tang, L1
Passeri, E1
Tufano, A1
Locatelli, M1
Lania, AG1
Ambrosi, B2
Corbetta, S1
Hadfield, CA1
Clayton, LA1
Clancy, MM1
Beck, SE1
Mangus, LM1
Montali, RJ1
Stocco, E1
Pelizzo, MR1
Grassetto, G1
Pagetta, C1
Larizza, D1
Massaro, A1
Marzola, MC1
Rubello, D1
Han, L1
Wang, J1
Shu, K1
Dodd, DE1
Pluta, LJ1
Sochaski, MA1
Funk, KA1
Thomas, RS1
Chandra, AK1
De, N1
Nishimura, N1
Yonemoto, J1
Miyabara, Y1
Sato, M1
Tohyama, C1
Vermiglio, F1
Lo Presti, VP1
Violi, MA1
Moleti, M1
Castagna, MG1
Finocchiaro, MD1
Mattina, F1
Mandolfino, M1
Zimbaro, G1
Trimarchi, F1
MALOOF, F1
ERNSTROM, U1
GYLLENSTEN, L1
ERNSTROEM, U2
Bhansali, A1
Sreenivasulu, P1
Khandelwal, N1
Masoodi, SR1
Vansell, NR1
Muppidi, JR1
Habeebu, SM1
Klaassen, CD2
Wang, JT1
Sun, D1
Zhang, H1
Cheng, WB1
Wu, DS1
Ashley, WW1
Ojemann, JG1
Park, TS1
Wippold, FJ1
Weber, G1
Vigone, MC1
Passoni, A1
Odoni, M1
Paesano, PL1
Dosio, F1
Proverbio, MC1
Corbetta, C1
Persani, L1
Chiumello, G1
Chan, P1
Mahler, J1
Travlos, G1
Nyska, A1
Wenk, M1
Joshi, AS1
Woolf, PD1
Burns-Naas, LA1
Zorbas, M1
Jessen, B1
Evering, W1
Stevens, G1
Ivett, JL1
Ryan, TE1
Cook, JC1
Capen, CC4
Chen, M1
Furman, G1
Theiss, JC1
Webber, S1
Wu, E1
Shetty, B1
Gasser, R1
McClain, RM1
Mancini, A1
Bianchi, A1
Fusco, A1
Sacco, E1
Leone, E1
Tilaro, L1
Porcelli, T1
Giampietro, A1
Principi, F1
De Marinis, L1
Littarru, GP1
Rivkees, SA1
Flynn, JC1
Gilbert, JA1
Meroueh, C1
Snower, DP1
David, CS1
Kong, YC1
Banga, JP1
Coelho-Palermo Cunha, G1
van Ravenzwaay, B1
Wakeling, J1
Smith, K1
Scase, T1
Kirkby, R1
Elliott, J1
Syme, H1
D'angelo, SA1
Collins, WT1
Elliot, I1
Gupta, M1
Hostetter, A1
Sheeler, L1
Skillern, P1
Tubbs, R1
Toru-Delbauffe, D1
Ohayon, R1
Pavlovic-Hournac, M1
Fukino, O1
Tamai, H1
Kumai, M1
Ohsako, N1
Kuma, K1
Nagataki, S1
Denef, JF2
Haumont, S2
Cornette, C2
Beckers, C2
Moccia, RD1
Leatherland, JF2
Sonstegard, RA1
Gresik, EW1
van der Noen, H1
Barka, T1
Jemec, B1
Phillips, ID1
Becks, GP1
Logan, A1
Wang, JF1
Smith, C1
Hill, DJ1
Mitsumori, K4
Onodera, H4
Takahashi, M5
Shimo, T1
Yasuhara, K4
Kitaura, K1
Hayashi, Y1
Gärtner, R1
Adams, C1
Dean, HJ1
Israels, SJ1
Patton, A1
Fewer, DH1
Trivedi, N1
Kakkar, R1
Srivastava, MK1
Mithal, A1
Raizada, RB1
Mizukami, Y1
Michigishi, T1
Nonomura, A1
Hashimoto, T1
Tonami, N1
Matsubara, F1
Takazakura, E1
Walker, RP1
Oslapas, R1
Ernst, K1
Hessel, P1
Nayyar, R1
Lawrence, AM2
Paloyan, E2
Rochefort, P1
Caillou, B1
Michiels, FM1
Ledent, C2
Talbot, M1
Schlumberger, M1
Lavelle, F1
Monier, R1
Feunteun, J1
Szabó, I1
Kapp, P1
Hotz, KJ1
Wilson, AG1
Thake, DC1
Roloff, MV1
Kronenberg, JM1
Brewster, DW1
Sagartz, JE1
Jhiang, SM1
Tong, Q1
Paloyan Walker, R1
Kazuko, E1
Gopalsami, C1
Bassali, J1
Zeiger, MA1
Saji, M1
Gusev, Y1
Westra, WH1
Takiyama, Y1
Dooley, WC1
Kohn, LD1
Levine, MA1
Otsuka, F1
Ogura, T1
Nakao, K1
Hayakawa, N1
Mimura, Y1
Yamauchi, T1
Makino, H1
Riesco, JM1
Juanes, JA1
Carretero, J1
Blanco, EJ1
Riesco-Lopez, JM1
Vázquez, G1
Vázquez, R1
Funakoshi, T2
Tamura, T2
Takegawa, K3
Stahl, JH2
Kendall, SK2
Brinkmeier, ML2
Greco, TL1
Watkins-Chow, DE1
Campos-Barros, A1
Lloyd, RV2
Camper, SA2
Ghannam, NN1
Hammami, MM1
Muttair, Z1
Bakheet, SM1
Usenko, VS1
Lepekhin, EA1
Lyzogubov, VV1
Kornilovska, IN1
Apostolov, EO1
Tytarenko, RG1
Witt, M1
Takagi, H2
Hirose, M3
Hood, A1
Hashmi, R1
Young, M1
Kattner, K1
Gupta, K1
Katsuya Lauer, A1
Balish, MJ1
Palmer, EA1
Tsuchiya, Y1
Ohno, H1
Satoh, H1
Sugawara, T1
Kajimura, T1
Nomura, M1
Goswami, R1
Tandon, N1
Sharma, R1
Kochupillai, N1
Manocha, SM1
Moulick, ND1
Shah, NS1
Koujitani, T1
Nasu, M1
Ikeda, T1
Nishikawa, A1
Son, HY1
Nakamura, H1
Miyauchi, M1
Imazawa, T1
Kimura, S1
Gordon, DF1
Ross, BD1
Sarapura, VD1
Dowding, JM1
Ridgway, EC1
Endo, K1
Kasagi, K1
Konishi, J1
Ikekubo, K1
Okuno, T1
Takeda, Y1
Mori, T1
Torizuka, K1
Bratusch-Marrain, P1
Haydl, H1
Waldhäusl, W1
Dudczak, R1
Graninger, W1
Petrova, GA1
Stockigt, JR1
Essex, WB1
West, RH1
Murray, RM1
Breidahl, HD1
Sonstegard, R1
Bykov, VL1
Dumont, JE1
Vassart, G1
Parmentier, M1
Tadmor, OP1
Barr, I1
Diamant, YZ1
Tseleni-Balafouta, S1
Katsouyanni, K1
Kitsopanides, J1
Koutras, DA1
Khmel'nitskiĭ, OK1
Brezhneva, VA1
Cao, SW1
Morinaga, Y1
Osame, S1
Sarashina, T1
Ichijo, S1
Chan, AW1
MacFarlane, IA1
Foy, PM1
Miles, JB1
Autelitano, F1
Santeusanio, G1
Di Tondo, U1
Costantino, AM1
Renda, F1
Autelitano, M1
Rognoni, JB2
Penel, C2
Bastiani, P2
Roccabianca, M1
Lemarchand-Beraud, T1
Ahmed, M1
Banna, M1
Sakati, N1
Woodhouse, N1
Kitahori, Y2
Ohshima, M2
Matsuki, H1
Konishi, N2
Hashimoto, H2
Minami, S2
Thamavit, W1
Hiasa, Y2
Atchison, JA1
Lee, PA1
Albright, AL1
Libbey, NP1
Nowakowski, KJ1
Tucci, JR1
Nishi, Y1
Hamamoto, K1
Kajiyama, M1
Fujita, A1
Kawamura, I1
Kagawa, Y1
Kajima, T1
Yamanaka, M1
Uozumi, T1
Katoh, Y1
Shimoyama, T1
Sakaguchi, Y1
Murata, Y1
van den Berg, KJ1
Zurcher, C1
Brouwer, A1
Sanders, JE1
Eigenberg, DA1
Bracht, LJ1
Wang, WR1
van Zwieten, MJ1
Farley, JD1
Toth, EL1
Ryan, EA1
Lipp, HP1
Schwegler, H1
Heimrich, B1
Driscoll, P1
Many, MC1
van den Hove-Vandenbroucke, MF1
Romeo, HE1
Boado, RJ1
Cardinali, DP1
Beck-Peccoz, P1
Travaglini, P1
Trotto, G1
Faglia, G1
Horvat, NM1
Horvat, BL1
Milković, K1
Milković, S1
Hung, W1
Chandra, R1
August, GP1
Altman, PR1
Lederer, J1
Bürgi, H1
Radvila, A1
Kohler, H1
Studer, H1
Johansson, H1
Nylander, G1
Jackson, IM1
Hall, R1
Block, MA1
Horn, RC1
Miller, JM1
Ochi, Y1
DeGroot, LJ1

Reviews

4 reviews available for thyroxine and Hyperplasia

ArticleYear
Primary hypothyroidism in a child leads to pituitary hyperplasia: A case report and literature review.
    Medicine, 2018, Volume: 97, Issue:42

    Topics: Child; Female; Hashimoto Disease; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; P

2018
Primary hypothyroidism in a 12-year-old girl with a suprasellar pituitary mass: rapid regression after thyroid replacement therapy: case report.
    Journal of neurosurgery, 2005, Volume: 102, Issue:4 Suppl

    Topics: Child; Female; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Pituitary Gland; Thy

2005
Pituitary hyperplasia secondary to primary hypothyroidism: a case report and review of the literature.
    Pituitary, 2005, Volume: 8, Issue:2

    Topics: Adult; Female; Hormone Replacement Therapy; Humans; Hyperplasia; Hypothyroidism; Pituitary Gland; Th

2005
Thyroxine treatment of benign goiter.
    Acta medica Austriaca, 1994, Volume: 21, Issue:2

    Topics: Animals; Goiter, Endemic; Growth Substances; Humans; Hyperplasia; Iodine; Rats; Thyroid Gland; Thyro

1994

Other Studies

118 other studies available for thyroxine and Hyperplasia

ArticleYear
A Case of Pituitary Hyperplasia due to Primary Hypothyroidism.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:1

    Topics: Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Pituitary Gland; Pituitary Neoplasm

2022
Reversible Tumorous Pituitary Enlargement due to Primary Hypothyroidism.
    The American journal of medicine, 2022, Volume: 135, Issue:6

    Topics: Humans; Hyperplasia; Hypothyroidism; Pituitary Gland; Thyroxine

2022
Pituitary hyperplasia in a girl with primary hypothyroidism.
    BMJ case reports, 2023, 11-23, Volume: 16, Issue:11

    Topics: Female; Humans; Hyperplasia; Hypothyroidism; Pituitary Diseases; Pituitary Gland; Pituitary Neoplasm

2023
Neurological manifestation in severe hypothyroidism in pregnancy.
    BMJ case reports, 2020, Dec-28, Volume: 13, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Antihypertensive Agents; Cesarean Section; Diagnosis, Differential;

2020
Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.
    Molecular and cellular endocrinology, 2018, 01-15, Volume: 460

    Topics: Animals; Apoptosis; Cattle; Cellular Senescence; Disease Models, Animal; DNA Damage; Enzyme Activati

2018
Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption.
    Neuro endocrinology letters, 2017, Volume: 38, Issue:4

    Topics: Adenoma; Adult; Diagnosis, Differential; Female; Humans; Hyperplasia; Hypothyroidism; Malabsorption

2017
Pituitary 'pseudotumor': an under-recognised complication of undertreated primary hypothyroidism.
    BMJ case reports, 2018, Jun-27, Volume: 2018

    Topics: Adenoma; Adult; Female; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Pituitary G

2018
Ultrasonic morphology of uterus and ovaries in girls with pituitary hyperplasia secondary to primary hypothyroidism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2013, Volume: 45, Issue:9

    Topics: Case-Control Studies; Child; Child, Preschool; Female; Hormones; Humans; Hyperplasia; Hypothyroidism

2013
Thyrotroph hyperplasia.
    Postgraduate medical journal, 2014, Volume: 90, Issue:1059

    Topics: Adult; Female; Gadolinium; Headache; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging

2014
Irreversible thyroid disruption induced after subchronic exposure to hexachlorobenzene in male rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Hexachlorobenzene; Hyperplasia; Hypertrophy; Male; Rats;

2016
Does exposure to thyroxine-mimics cause feline thyroid hyperplasia?
    The Veterinary record, 2014, Sep-06, Volume: 175, Issue:9

    Topics: Animals; Cat Diseases; Cats; Environmental Exposure; Environmental Pollutants; Food Additives; Hyper

2014
Reversible growth failure and complete GH deficiency in a 4-year-old girl with very early Hashimoto's thyroiditis and subsequent hyperplasia of pituitary thyrotroph cells.
    European journal of pediatrics, 2016, Volume: 175, Issue:8

    Topics: Brain; Child, Preschool; Female; Growth Disorders; Growth Hormone; Hashimoto Disease; Humans; Hyperp

2016
New Murine Model of Early Onset Autoimmune Thyroid Disease/Hypothyroidism and Autoimmune Exocrinopathy of the Salivary Gland.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 09-15, Volume: 197, Issue:6

    Topics: Animals; Autoimmune Diseases; CD28 Antigens; CD40 Antigens; Cells, Cultured; Disease Models, Animal;

2016
[Van Wyk-Grumbach syndrome: A case report and 
literature review].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Dec-28, Volume: 41, Issue:12

    Topics: Adolescent; Congenital Hypothyroidism; Diagnosis, Differential; Diagnostic Errors; Female; Humans; H

2016
Hyperplastic goitre and mortality in captive-reared black stilts ( Himantopus novaezelandiae ).
    New Zealand veterinary journal, 2008, Volume: 56, Issue:3

    Topics: Animals; Animals, Wild; Bird Diseases; Birds; Conservation of Natural Resources; Goiter; Hyperplasia

2008
Index of suspicion.
    Pediatrics in review, 2008, Volume: 29, Issue:7

    Topics: Adolescent; Child; Diagnosis, Differential; Esophageal Perforation; Female; Humans; Hyperplasia; Hyp

2008
Rapid progression of hypothyroidism-related pituitary hyperplasia.
    Journal of neurosurgery. Pediatrics, 2008, Volume: 2, Issue:3

    Topics: Adenoma; Child; Diagnosis, Differential; Disease Progression; Female; Humans; Hyperplasia; Hypothyro

2008
[Time-effect study of propylthiouracil-induced thyroid gland hyperplasia].
    Wei sheng yan jiu = Journal of hygiene research, 2009, Volume: 38, Issue:1

    Topics: Animals; Antithyroid Agents; Dose-Response Relationship, Drug; Hyperplasia; Male; Proliferating Cell

2009
Thyroid histopathology assessments for the amphibian metamorphosis assay to detect thyroid-active substances.
    Toxicologic pathology, 2009, Volume: 37, Issue:4

    Topics: Animals; Atrophy; Biological Assay; Histocytochemistry; Hyperplasia; Hypertrophy; Larva; Metamorphos

2009
[Pituitary hyperplasia secondary to primary hypothyroidism in children: report of 8 cases].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:1

    Topics: Body Height; Child; Child, Preschool; Female; Follow-Up Studies; Human Growth Hormone; Humans; Hyper

2010
Pituitary hyperplasia in children with short stature and primary hypothyroidism.
    Indian pediatrics, 2010, Volume: 47, Issue:10

    Topics: Body Height; Child; Child, Preschool; Female; Growth; Human Growth Hormone; Humans; Hyperplasia; Hyp

2010
Large pituitary hyperplasia in severe primary hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:1

    Topics: Cortisone; Female; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Pituitary Diseas

2011
Proliferative thyroid lesions in three diplodactylid geckos: Nephrurus amyae, Nephrurus levis, and Oedura marmorata.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2012, Volume: 43, Issue:1

    Topics: Animals; Animals, Zoo; Carcinoma; Fatal Outcome; Hyperplasia; Hypothyroidism; Lizards; Male; Thyroid

2012
Mini-invasive videoassisted thyroid lobectomy for neonatal hyperfunctioning adenoma related to a somatic TSHr gene mutation.
    Annales d'endocrinologie, 2012, Volume: 73, Issue:3

    Topics: Adenoma; Amino Acid Substitution; Exons; Hormone Replacement Therapy; Humans; Hyperplasia; Hyperthyr

2012
Pituitary tumorous hyperplasia due to primary hypothyroidism.
    Acta neurochirurgica, 2012, Volume: 154, Issue:8

    Topics: Adolescent; Adult; Female; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Male; Mi

2012
Subchronic thyroid toxicity evaluation of 4,4'-methylenebis(N,N'-dimethyl)aniline in Fischer 344 rats.
    Journal of toxicology and environmental health. Part A, 2012, Volume: 75, Issue:11

    Topics: Administration, Oral; Aniline Compounds; Animals; Carcinogens; Dose-Response Relationship, Drug; Env

2012
Catechin induced modulation in the activities of thyroid hormone synthesizing enzymes leading to hypothyroidism.
    Molecular and cellular biochemistry, 2013, Volume: 374, Issue:1-2

    Topics: Animals; Catechin; Hyperplasia; Hypertrophy; Hypothyroidism; Iodide Peroxidase; Male; Rats; Rats, Sp

2013
Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Endocrinology, 2003, Volume: 144, Issue:5

    Topics: Administration, Oral; Animals; Cytochrome P-450 CYP1A1; Drug Administration Schedule; Environmental

2003
Changes in both size and cytological features of thyroid nodule after levothyroxine treatment.
    Clinical endocrinology, 2003, Volume: 59, Issue:3

    Topics: Adult; Aged; Antithyroid Agents; Biopsy, Needle; Chi-Square Distribution; Depression, Chemical; Fema

2003
The effect of hypophysectomy and of thyroxine on the radiation-induced changes in the rat thyroid.
    Endocrinology, 1955, Volume: 56, Issue:2

    Topics: Animals; Hyperplasia; Hypertrophy; Hypophysectomy; Iodine; Iodine Radioisotopes; Pituitary Gland; Ra

1955
The histologic picture in thyroxin-induced lymphatic hyperplasia: a quantitative examination on guinea pig.
    Acta pathologica et microbiologica Scandinavica, 1959, Volume: 47

    Topics: Guinea Pigs; Hyperplasia; Lymph Nodes; Lymphatic Vessels; Thyroxine

1959
INFLUENCE OF THE THYMUS ON THYROXIN-INDUCED LYMPHATIC HYPERPLASIA IN YOUNG GUINEA-PIGS. 1. TREATMENT WITH THYROXIN ONE MONTH AFTER THYMECTOMY.
    Acta pathologica et microbiologica Scandinavica, 1965, Volume: 64

    Topics: Animals; Guinea Pigs; Hyperplasia; Lymph Nodes; Lymphatic Vessels; Organ Size; Pharmacology; Physiol

1965
INFLUENCE OF THE THYMUS ON TRYROXIN-INDUCED LYMPHATIC HYPERPLASIA IN YOUNG GUINEA-PIGS. 2. TREATMENT WITH THYROXIN SHORTLY AFTER THYMECTOMY.
    Acta pathologica et microbiologica Scandinavica, 1965, Volume: 64

    Topics: Animals; Guinea Pigs; Hyperplasia; Lymphatic Vessels; Organ Size; Pharmacology; Physiology; Research

1965
Reversibility of thyrotroph hyperplasia after L-thyroxine replacement therapy in patients with juvenile primary hypothyroidism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Basophils; Contrast Media; Female; Hormone Replacement Therapy; Humans; Hyperplas

2004
Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB).
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:1

    Topics: Adenoma; Animals; Antithyroid Agents; Body Weight; Carcinoma; Chlorodiphenyl (54% Chlorine); Eating;

2004
[Time course of the disruption of rat's thyroid function by pesticide N'N-methylene-bis].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Female; Hyperplasia; Male; Pesticides; Rats; Rats, Spragu

2004
Congenital hypothyroidism with gland in situ: diagnostic re-evaluation.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:6

    Topics: Congenital Hypothyroidism; Female; Humans; Hyperplasia; Hypothyroidism; Infant, Newborn; Iodine; Mal

2005
Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.
    Archives of toxicology, 2006, Volume: 80, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Female; Hyperplasia; Hypertrophy; Imidazoles; Incidence;

2006
Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia.
    Human & experimental toxicology, 2005, Volume: 24, Issue:12

    Topics: Adenocarcinoma, Follicular; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogen

2005
Coenzyme Q10 evaluation in pituitary-adrenal axis disease: preliminary data.
    BioFactors (Oxford, England), 2005, Volume: 25, Issue:1-4

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adult; Aged; Cholesterol; Coenzymes;

2005
Thyrotrope hyperplasia.
    Journal of pediatric endocrinology & metabolism : JPEM, 2006, Volume: 19, Issue:12

    Topics: Child; Female; Humans; Hyperplasia; Magnetic Resonance Imaging; Pituitary Diseases; Thyrotrophs; Thy

2006
Chronic exposure in vivo to thyrotropin receptor stimulating monoclonal antibodies sustains high thyroxine levels and thyroid hyperplasia in thyroid autoimmunity-prone HLA-DRB1*0301 transgenic mice.
    Immunology, 2007, Volume: 122, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Autoimmunity; Drug Administration Schedule; Female; Genetic Predisp

2007
Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.
    Regulatory toxicology and pharmacology : RTP, 2007, Volume: 48, Issue:3

    Topics: Animals; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Hyperplasia; Hypertrophy; Iodine Radioi

2007
Subclinical hyperthyroidism in cats: a spontaneous model of subclinical toxic nodular goiter in humans?
    Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:12

    Topics: Adenoma; Animals; Cat Diseases; Cats; Disease Models, Animal; Goiter, Nodular; Humans; Hyperplasia;

2007
Pituitary-Thyroid interrelations in maternal, fetal and neonatal guinea pigs.
    Endocrinology, 1967, Volume: 81, Issue:1

    Topics: Animals; Animals, Newborn; Female; Fetus; Guinea Pigs; Hyperplasia; Maternal-Fetal Exchange; Pituita

1967
Ultrastructural and functional alterations of the rat thyroid gland produced by polychlorinated biphenyls compared with iodide excess and deficiency, and thyrotropin and thyroxine administration.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1980, Volume: 33, Issue:3

    Topics: Animals; Hyperplasia; Hypertrophy; Iodides; Lysosomes; Male; Microscopy, Electron; Microvilli; Polyc

1980
Immunologic studies in two patients with persistent lymphocytic thyroiditis, thyrotoxicosis, and low radioactive iodine uptake.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adult; Female; Humans; Hyperplasia; Hyperthyroidism; Immunoenzyme Techniques; Iodine Radioisotopes;

1984
Protein kinase patterns in hyperplastic rat thyroids and in human non-toxic nodular goitres.
    Molecular and cellular endocrinology, 1983, Volume: 33, Issue:2-3

    Topics: Animals; Centrifugation, Density Gradient; Goiter, Nodular; Humans; Hyperplasia; Male; Protamine Kin

1983
Responses to TRH, T3 suppression tests and histological findings by needle biopsy in patients with simple goitre in Japan.
    Acta endocrinologica, 1982, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Aged; Biopsy, Needle; Child; Female; Goiter; Humans; Hyperplasia; Male; Middle Ag

1982
Correlated functional and morphometric study of thyroid hyperplasia induced by iodine deficiency.
    Endocrinology, 1981, Volume: 108, Issue:6

    Topics: Animals; Autoradiography; Epithelium; Female; Hyperplasia; Iodine; Male; Mice; Monoiodotyrosine; Org

1981
Quantitative interlake comparison of thyroid pathology in Great Lakes coho (Oncorhynchus kisutch) and chinook (Oncorhynchus tschawytscha) salmon.
    Cancer research, 1981, Volume: 41, Issue:6

    Topics: Animals; British Columbia; Environmental Exposure; Female; Fish Diseases; Fishes; Goiter; Great Lake

1981
Hypertrophic and hyperplastic effects of thyroxine on the submandibular gland of the mouse.
    The Anatomical record, 1981, Volume: 200, Issue:4

    Topics: Animals; Autoradiography; DNA; Female; Hyperplasia; Hypertrophy; Mice; Mice, Inbred Strains; Submand

1981
Studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment.
    Cancer, 1980, Apr-15, Volume: 45, Issue:8

    Topics: Adenoma; Adrenal Glands; Animals; Body Weight; Drug Combinations; Hyperplasia; Hypophysectomy; Imida

1980
Altered expression of insulin-like growth factor-I (IGF-I) and IGF binding proteins during rat thyroid hyperplasia and involution.
    Growth factors (Chur, Switzerland), 1994, Volume: 10, Issue:3

    Topics: Animals; Carrier Proteins; Gene Expression Regulation, Neoplastic; Goiter; Hyperplasia; Hypertrophy;

1994
Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors.
    Cancer letters, 1995, Jun-08, Volume: 92, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Disease Progression; Goiter; Hyperplasia; Male; Nitrosamines; O

1995
Primary hypothyroidism with intracranial hypertension and pituitary hyperplasia.
    Pediatric neurology, 1994, Volume: 10, Issue:2

    Topics: Cerebrospinal Fluid Pressure; Child; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperpl

1994
Effect of oral administration of fungicide-mancozeb on thyroid gland of rat.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Hyperplasia; Hypertrophy; Iodide Peroxidase; Male; Maneb

1993
Iodine-induced hypothyroidism: a clinical and histological study of 28 patients.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2

    Topics: Adult; Aged; Colloids; Epithelium; Female; Humans; Hyperplasia; Hypothyroidism; Immunohistochemistry

1993
Hyperparathyroidism induced by hypothyroidism.
    The Laryngoscope, 1993, Volume: 103, Issue:3

    Topics: Administration, Oral; Animals; Calcium; Delayed-Action Preparations; Drug Implants; Female; Hyperpar

1993
Thyroid pathologies in transgenic mice expressing a human activated Ras gene driven by a thyroglobulin promoter.
    Oncogene, 1996, Jan-04, Volume: 12, Issue:1

    Topics: Animals; Calcitonin; Carcinoma, Papillary; Cattle; Female; Genes, ras; Humans; Hyperplasia; Male; Mi

1996
[The effect of carbamide feeding over a long period of time on thyroid gland activity in bulls].
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1995, Volume: 42, Issue:10

    Topics: Animal Feed; Animals; Cattle; Hyperplasia; In Vitro Techniques; Male; Microscopy, Electron; Nitrates

1995
Mechanism of thiazopyr-induced effects on thyroid hormone homeostasis in male Sprague-Dawley rats.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Adenoma; Animals; Bile; Diet; Dose-Response Relationship, Drug; Enzyme Induction; Glucuronosyltransf

1997
Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene.
    Laboratory investigation; a journal of technical methods and pathology, 1997, Volume: 76, Issue:3

    Topics: Animals; Cattle; Drosophila Proteins; Female; Humans; Hyperplasia; Iodine; Male; Mice; Mice, Inbred

1997
Hyperparathyroidism associated with a chronic hypothyroid state.
    The Laryngoscope, 1997, Volume: 107, Issue:7

    Topics: Adenoma; Animals; Antithyroid Agents; Calcium; Chronic Disease; Disease Models, Animal; Female; Hype

1997
Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Adenylyl Cyclases; Aneuploidy; Animals; Cell Cycle; Cholera Toxin; Cyclic AMP; Disease Models, Anima

1997
Cushing's syndrome due to unilateral adrenocortical hyperplasia.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Corticotropin

1998
Cell proliferation and apoptosis of thyroid follicular cells are involved in the involution of experimental non-tumoral hyperplastic goiter.
    Anatomy and embryology, 1998, Volume: 198, Issue:6

    Topics: Animals; Antithyroid Agents; Apoptosis; Bromodeoxyuridine; Cell Division; Epithelial Cells; Female;

1998
Promoting effects of kojic acid due to serum TSH elevation resulting from reduced serum thyroid hormone levels on development of thyroid proliferative lesions in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
    Carcinogenesis, 1999, Volume: 20, Issue:1

    Topics: Adenoma; Animals; Biotransformation; Carcinogens; Feedback; Food Additives; Glucuronosyltransferase;

1999
Thyroid hormone is essential for pituitary somatotropes and lactotropes.
    Endocrinology, 1999, Volume: 140, Issue:4

    Topics: Animals; Cell Count; Cell Division; Dwarfism; Glycoprotein Hormones, alpha Subunit; Growth Hormone;

1999
Primary hypothyroidism-associated TSH-secreting pituitary adenoma/hyperplasia presenting as a bleeding nasal mass and extremely elevated TSH level.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:6

    Topics: Adenoma; Adult; Epistaxis; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Male; Pi

1999
The influence of maternal hypothyroidism and radioactive iodine on rat embryonal development: thyroid C-cells.
    The Anatomical record, 1999, 09-01, Volume: 256, Issue:1

    Topics: Animals; Animals, Newborn; Calcitonin; Female; Hyperplasia; Hypertrophy; Hypothyroidism; Immunohisto

1999
Time course observation of thyroid proliferative lesions and serum levels of related hormones in rats treated with kojic acid after DHPN initiation.
    The Journal of toxicological sciences, 1999, Volume: 24, Issue:3

    Topics: Adenoma; Animals; Body Weight; Cocarcinogenesis; Glucuronosyltransferase; Hyperplasia; Liver; Male;

1999
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
    Toxicology and applied pharmacology, 1999, Oct-15, Volume: 160, Issue:2

    Topics: Animals; Cell Count; Cell Division; Chlorodiphenyl (54% Chlorine); Enzyme Activation; Hyperplasia; H

1999
Pituitary hyperplasia resulting from primary hypothyroidism mimicking macroadenomas.
    British journal of neurosurgery, 1999, Volume: 13, Issue:2

    Topics: Adenoma; Adolescent; Adult; Child; Diagnosis, Differential; Female; Humans; Hyperplasia; Hypothyroid

1999
Persistent hyperplastic primary vitreous associated with septo-optic-pituitary dysplasia and schizencephaly.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:4

    Topics: Abnormalities, Multiple; Adolescent; Adrenocorticotropic Hormone; Brain; Eye Abnormalities; Fundus O

2000
Thyroid hypertrophic effect of semotiadil fumarate, a new calcium antagonist, in rats.
    The Journal of toxicological sciences, 2000, Volume: 25, Issue:2

    Topics: Animals; Calcium Channel Blockers; Female; Glucuronosyltransferase; Hyperplasia; Hypertrophy; Liver;

2000
Residual pituitary enlargement in primary hypothyroidism despite 1 1/2 years of L-thyroxine therapy.
    Australasian radiology, 1999, Volume: 43, Issue:1

    Topics: Adult; Humans; Hyperplasia; Hypothyroidism; Magnetic Resonance Imaging; Male; Pituitary Gland; Thyro

1999
Primary hypothyroidism presenting as a pituitary gland enlargement with regression following thyroxine therapy.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:6

    Topics: Adult; Humans; Hyperplasia; Hypothyroidism; Male; Pituitary Gland; Thyroxine; Tomography, X-Ray Comp

2000
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.
    Carcinogenesis, 2001, Volume: 22, Issue:4

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Hyp

2001
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:4

    Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycine max; Hyper

2001
Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:12

    Topics: Animals; Blotting, Northern; Female; Glycoprotein Hormones, alpha Subunit; Hyperplasia; Hypothyroidi

2001
Detection and properties of TSH-binding inhibitor immunoglobulins in patients with Graves' disease and Hashimoto's thyroiditis.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Female; Graves Disease; Humans; Hyperplasia; Immunoglobulin G; Immunoglobulins, T

1978
Familial thyroxine-binding globulin deficiency in association with non-toxic goitre.
    Acta endocrinologica, 1979, Volume: 91, Issue:1

    Topics: Adult; Child, Preschool; Female; Goiter; Humans; Hyperplasia; Male; Middle Aged; Pedigree; Radioimmu

1979
[Biological effect of TSH and its binding with the thyrocytes in functional thyroid states].
    Meditsinskaia radiologiia, 1979, Volume: 24, Issue:12

    Topics: Animals; Atrophy; Guinea Pigs; Hyperplasia; In Vitro Techniques; Male; Protein Binding; Rabbits; Rat

1979
Visual failure during replacement therapy in primary hypothyroidism with pituitary enlargement.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:5

    Topics: Adult; Female; Humans; Hyperplasia; Hypothyroidism; Pituitary Diseases; Prolactin; Thyrotropin; Thyr

1976
The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario.
    Cancer research, 1976, Volume: 36, Issue:12

    Topics: Animals; Canada; Fish Diseases; Goiter; Hyperplasia; Iodine; Pituitary Gland; Salmon; Seasons; Thyro

1976
[Method of complex morphofunctional study of the capillary bed of the thyroid gland].
    Arkhiv anatomii, gistologii i embriologii, 1975, Volume: 68, Issue:5

    Topics: Alkaline Phosphatase; Animals; Capillaries; Histocytochemistry; Hyperplasia; Male; Methylthiouracil;

1975
Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism.
    The EMBO journal, 1992, Volume: 11, Issue:2

    Topics: Adenosine; Animals; Blotting, Northern; Brain; Cattle; Cell Membrane; Cyclic AMP; Dogs; Hyperplasia;

1992
[Primary hypothyroidism presenting with amenorrhea, galactorrhea, hyperprolactinemia and enlarged pituitary].
    Harefuah, 1992, Jan-15, Volume: 122, Issue:2

    Topics: Adenoma; Adult; Amenorrhea; Diagnosis, Differential; Female; Galactorrhea; Humans; Hyperplasia; Hype

1992
The outcome of benign thyroid nodules correlates with the findings of fine needle biopsy.
    Thyroidology, 1991, Volume: 3, Issue:2

    Topics: Adult; Aged; Biopsy, Needle; Colloids; Female; Fibrosis; Humans; Hyperplasia; Lymphocytes; Male; Mid

1991
[Functional morphology of peripheral endocrine glands after thymic polypeptide administration in secondary immunodeficiency].
    Arkhiv patologii, 1991, Volume: 53, Issue:1

    Topics: Adjuvants, Immunologic; Adrenal Cortex; Animals; Epithelium; Guinea Pigs; Hyperplasia; Immune Tolera

1991
[Study of the pathogenesis of high iodine-induced goiter].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1990, Volume: 19, Issue:4

    Topics: Animals; Chickens; Epithelium; Goiter; Hyperplasia; Sodium Iodide; Thyroid Gland; Thyrotropin; Thyro

1990
Clinicopathological observations on calves with enzootic goiter.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1990, Volume: 52, Issue:6

    Topics: Animals; Animals, Newborn; Cattle; Cattle Diseases; Female; Goiter, Endemic; Hyperplasia; Male; Thyr

1990
Pituitary enlargement and hyperprolactinaemia due to primary hypothyroidism: errors and delays in diagnosis.
    British journal of neurosurgery, 1990, Volume: 4, Issue:2

    Topics: Adult; Female; Humans; Hyperplasia; Hyperprolactinemia; Hypothyroidism; Male; Middle Aged; Pituitary

1990
Immunohistochemical study of solid cell nests of the thyroid gland found from an autopsy study.
    Cancer, 1987, Feb-01, Volume: 59, Issue:3

    Topics: Aged; Autopsy; Calcitonin; Female; Humans; Hyperplasia; Immunoenzyme Techniques; Keratins; Male; Mid

1987
Down regulation of hypertrophied follicular cell volume in thyroid hyperplastic gland.
    Histology and histopathology, 1989, Volume: 4, Issue:2

    Topics: Animals; Down-Regulation; Hyperplasia; Iodides; Iodine; Iodine Radioisotopes; Male; Microscopy, Elec

1989
Pituitary gland enlargement in primary hypothyroidism: a report of 5 cases with follow-up data.
    Hormone research, 1989, Volume: 32, Issue:5-6

    Topics: Adolescent; Adult; Child; Female; Humans; Hyperplasia; Hyperprolactinemia; Hypothyroidism; Pituitary

1989
Promoting effect of 2,4-diaminoanisole sulfate on rat thyroid carcinogenesis.
    Cancer letters, 1989, Volume: 45, Issue:2

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Cocarcinogenesis; Hair Dyes; Hair Preparation

1989
Reversible suprasellar pituitary mass secondary to hypothyroidism.
    JAMA, 1989, Dec-08, Volume: 262, Issue:22

    Topics: Child; Child, Preschool; Female; Humans; Hyperplasia; Hypertrophy; Hypothyroidism; Magnetic Resonanc

1989
Involution of hyperplastic goitre in the adult male rat. Tissue compartment process with early iodide effect: a stereological and biochemical study.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1987, Volume: 53, Issue:3

    Topics: Animals; Cell Count; DNA; Epithelium; Goiter; Homeostasis; Hyperplasia; Iodides; Male; Proteins; Rat

1987
C-cell hyperplasia of the thyroid in a patient with goitrous hypothyroidism and Hashimoto's thyroiditis.
    The American journal of surgical pathology, 1989, Volume: 13, Issue:1

    Topics: Calcitonin; Carcinoembryonic Antigen; Goiter; Humans; Hyperplasia; Hypothyroidism; Male; Middle Aged

1989
Pituitary enlargement, hypertrichosis and blunted growth hormone secretion in primary hypothyroidism.
    Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:1

    Topics: Adolescent; Child; Female; Growth Hormone; Humans; Hyperplasia; Hypertrichosis; Hypothyroidism; Male

1989
Effects of castration before and after treatment with N-bis (2-hydroxypropyl)-nitrosamine (DHPN) on the development of thyroid tumors in rats treated with DHPN followed by phenobarbital.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:10

    Topics: Animals; Body Weight; Gonadal Steroid Hormones; Hyperplasia; Male; Nitrosamines; Orchiectomy; Organ

1987
Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys.
    Toxicology letters, 1988, Volume: 41, Issue:1

    Topics: Animals; Callitrichinae; Female; Hyperplasia; Polychlorinated Biphenyls; Thyroid Gland; Thyrotropin;

1988
Thyroid and liver trophic changes in rats secondary to liver microsomal enzyme induction caused by an experimental leukotriene antagonist (L-649,923).
    Toxicology and applied pharmacology, 1988, Sep-30, Volume: 95, Issue:3

    Topics: Animals; Enzyme Induction; Female; Glucuronosyltransferase; Hyperplasia; In Vitro Techniques; Liver;

1988
Primary hypothyroidism presenting as growth delay and pituitary enlargement.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1988, Volume: 15, Issue:1

    Topics: Child; Growth Disorders; Humans; Hyperplasia; Hypothyroidism; Male; Pituitary Gland; Thyroxine; Tomo

1988
Infrapyramidal mossy fibers and two-way avoidance learning: developmental modification of hippocampal circuitry and adult behavior of rats and mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:6

    Topics: Animals; Avoidance Learning; Behavior, Animal; Hippocampus; Hyperplasia; Mice; Mice, Inbred Strains;

1988
Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Animals; Diet; Female; Hyperplasia; Iodine; Mice; Mice, Inbred C3H; Thyroid Gland; Thyroxine; Triiod

1985
Role of the sympathetic nervous system in the control of thyroid compensatory growth of normal and hypophysectomized rats.
    Neuroendocrinology, 1985, Volume: 40, Issue:4

    Topics: Animals; Female; Ganglia, Sympathetic; Hyperplasia; Hypophysectomy; Male; Pituitary Gland; Rats; Rat

1985
[Hypothalamo-pituitary-adrenal function in hyperthyroidism and hypothyroidism].
    Folia endocrinologica, 1970, Volume: 23, Issue:4

    Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Dexamethasone; Female; Graves

1970
Influence of high level of endogenous Glucocorticoids on the histology of fetal rat thyroid.
    Endokrinologie, 1973, Volume: 61, Issue:1

    Topics: Adrenal Glands; Animals; Female; Glucocorticoids; Hormones, Ectopic; Hyperplasia; Neoplasm Transplan

1973
Clinical, laboratory, and histologic observations in euthyroid children and adolescents with goiters.
    The Journal of pediatrics, 1973, Volume: 82, Issue:1

    Topics: Adenoma; Adolescent; Autoantibodies; Child; Child, Preschool; Diagnosis, Differential; Goiter; Human

1973
[Thyroid gland in acromegaly].
    Actualites endocrinologiques, 1973, Volume: 13, Issue:0

    Topics: Acromegaly; Adenoma; Adult; Female; Humans; Hyperplasia; Hyperthyroidism; Iodine; Iodine Radioisotop

1973
Effects of pharmacological doses of iodide on the hyperplastic rat thyroid gland. Roles of intrathyroidal iodide, thyrotropin and thyroglobulin in the Wolff-Chaikoff phenomenon.
    Endocrinology, 1974, Volume: 95, Issue:2

    Topics: Animals; Centrifugation, Zonal; Diet; Hyperplasia; Iodides; Iodine; Iodine Radioisotopes; Propylthio

1974
Effect of iodine and thyroxine on the thyroid in thiouracil-treated rats.
    Acta Societatis Medicorum Upsaliensis, 1969, Volume: 74, Issue:3-4

    Topics: Angiography; Animals; Contrast Media; Depression, Chemical; Drug Synergism; Hyperplasia; Iodine; Mal

1969
Pituitary enlargement resulting from primary thyroid disease.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:6

    Topics: Exudates and Transudates; Eye Diseases; Female; Humans; Hyperplasia; Hypothyroidism; Middle Aged; Pi

1970
Hazards in the diagnosis and management of certain thyroid nodules in children.
    American journal of surgery, 1970, Volume: 120, Issue:4

    Topics: Adolescent; Child; Congenital Hypothyroidism; Diagnosis, Differential; Female; Goiter; Humans; Hyper

1970
Stimulation of thyroid hyperplasia and protein synthesis by LATS.
    Endocrinology, 1969, Volume: 85, Issue:2

    Topics: Animals; Female; Goiter; Hyperplasia; Leucine; Long-Acting Thyroid Stimulator; Mice; Organ Size; Pro

1969