Page last updated: 2024-11-06

thyroxine and Hyperphagia

thyroxine has been researched along with Hyperphagia in 16 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Hyperphagia: Ingestion of a greater than optimal quantity of food.

Research Excerpts

ExcerptRelevanceReference
"The possible role of neuropeptide Y (NPY) was studied in rats with hypermetabolism and hyperphagia induced by thyroxine (50-100-200 microg/day s."7.73Hyperphagia of hyperthyroidism: is neuropeptide Y involved? ( Balaskó, M; Jech-Mihálffy, A; Pétervári, E; Székely, M, 2005)
"The factors regulating serum leptin concentration and its relationship to the hyperphagia of lactation have been investigated in rats."7.72Regulation of serum leptin and its role in the hyperphagia of lactation in the rat. ( Denis, RG; Vernon, RG; Williams, G, 2003)
" He had seizures attacks and apnea from the second week of his life."3.78Early-onset severe obesity with ACTH deficiency and red hair in a boy: the POMC deficiency. ( Aldemir, O; Ozen, S, 2012)
" Here we demonstrate that either whole-body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activity of hypothalamic AMP-activated protein kinase (AMPK), increases sympathetic nervous system (SNS) activity and upregulates thermogenic markers in brown adipose tissue (BAT)."3.76Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. ( Agassandian, K; Carling, D; Chatterjee, K; Diéguez, C; Gallego, R; González, CR; Lage, R; Lelliott, C; López, M; Martínez de Morentin, PB; Morgan, DA; Nogueiras, R; Oresic, M; Rahmouni, K; Rodríguez-Cuenca, S; Saha, AK; Schoenmakers, E; Tovar, S; Varela, L; Vázquez, MJ; Velagapudi, VR; Vidal-Puig, A, 2010)
" Rats raised in a small litter can develop hyperinsulinaemia, hyperphagia, hyperleptinaemia and hypertension as adults."3.75Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats. ( de Moura, EG; Dutra, SC; Lisboa, PC; Passos, MC; Rodrigues, AL, 2009)
"The possible role of neuropeptide Y (NPY) was studied in rats with hypermetabolism and hyperphagia induced by thyroxine (50-100-200 microg/day s."3.73Hyperphagia of hyperthyroidism: is neuropeptide Y involved? ( Balaskó, M; Jech-Mihálffy, A; Pétervári, E; Székely, M, 2005)
"The factors regulating serum leptin concentration and its relationship to the hyperphagia of lactation have been investigated in rats."3.72Regulation of serum leptin and its role in the hyperphagia of lactation in the rat. ( Denis, RG; Vernon, RG; Williams, G, 2003)
" In young adult rats, mixed calorie overfeeding increases triiodothyronine production and decreases weight gain efficiency compared with chow diets."3.68Increasing age impairs the thyroid hormone response to overfeeding. ( Katzeff, HL, 1990)
"Metabolic responses to 20 days of overeating were examined in five healthy volunteers."1.27Some metabolic effects of overeating in man. ( Campbell, RG; Seaton, TB; Welle, SL, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozen, S1
Aldemir, O1
Zhao, Y1
Xue, Q1
Su, X1
Xie, L1
Yan, Y1
Steinman, AD1
Zheng, F1
Guo, G1
Wang, BL1
Liang, DC1
Zhang, R1
Zhang, JY1
Zhao, XQ1
Chen, ZP1
Rodrigues, AL1
de Moura, EG1
Passos, MC1
Dutra, SC1
Lisboa, PC1
López, M1
Varela, L1
Vázquez, MJ1
Rodríguez-Cuenca, S1
González, CR1
Velagapudi, VR1
Morgan, DA1
Schoenmakers, E1
Agassandian, K1
Lage, R1
Martínez de Morentin, PB1
Tovar, S1
Nogueiras, R1
Carling, D1
Lelliott, C1
Gallego, R1
Oresic, M1
Chatterjee, K1
Saha, AK1
Rahmouni, K1
Diéguez, C1
Vidal-Puig, A1
Preston, E1
Cooney, GJ1
Wilks, D1
Baran, K1
Zhang, L1
Kraegen, EW1
Sainsbury, A1
Denis, RG1
Williams, G1
Vernon, RG1
Pétervári, E1
Balaskó, M1
Jech-Mihálffy, A1
Székely, M1
Mitchell, JE1
Bantle, JP1
Welle, S1
O'Connell, M1
Danforth, E1
Campbell, R1
van der Kroon, PH1
Wittgen-Struik, G1
Vermeulen, L1
Almeida, NG1
Levitsky, DA1
Strupp, B1
Katzeff, HL1
Welle, SL1
Seaton, TB1
Campbell, RG1
Harris, RB1
Kasser, TR1
Martin, RJ1
Naim, M1
Brand, JG1
Kare, MR1
Carpenter, RG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Brown Adipose Tissue Activity and Thyroid Hormone[NCT02499471]12 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

16 other studies available for thyroxine and Hyperphagia

ArticleYear
Early-onset severe obesity with ACTH deficiency and red hair in a boy: the POMC deficiency.
    Genetic counseling (Geneva, Switzerland), 2012, Volume: 23, Issue:4

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Apnea; Caloric Restric

2012
Microcystin-LR induced thyroid dysfunction and metabolic disorders in mice.
    Toxicology, 2015, Feb-03, Volume: 328

    Topics: Animals; Behavior, Animal; Biomarkers; Blood Glucose; Dose-Response Relationship, Drug; Eating; Endo

2015
[Overdose of iodine on expression of CCK gene in rat brains].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2008, Volume: 42, Issue:3

    Topics: Animals; Brain; Cholecystokinin; Drug Overdose; Female; Food, Formulated; Gene Expression; Hyperphag

2008
Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.
    The Journal of physiology, 2009, Jun-01, Volume: 587, Issue:Pt 11

    Topics: Age Factors; Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blotting,

2009
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance.
    Nature medicine, 2010, Volume: 16, Issue:9

    Topics: Adipose Tissue, Brown; Agouti-Related Protein; AMP-Activated Protein Kinases; Animals; Arcuate Nucle

2010
Central neuropeptide Y infusion and melanocortin 4 receptor antagonism inhibit thyrotropic function by divergent pathways.
    Neuropeptides, 2011, Volume: 45, Issue:6

    Topics: Adipose Tissue, Brown; Agouti-Related Protein; Animals; Body Weight; Corticosterone; Eating; Energy

2011
Regulation of serum leptin and its role in the hyperphagia of lactation in the rat.
    The Journal of endocrinology, 2003, Volume: 176, Issue:2

    Topics: Animals; Body Weight; Bromocriptine; Circadian Rhythm; Diet; Female; Hormone Antagonists; Hyperphagi

2003
Hyperphagia of hyperthyroidism: is neuropeptide Y involved?
    Regulatory peptides, 2005, Volume: 131, Issue:1-3

    Topics: Animals; Body Temperature; Body Weight; Eating; Energy Metabolism; Female; Food Deprivation; Hyperph

2005
Metabolic and endocrine investigations in women of normal weight with the bulimia syndrome.
    Biological psychiatry, 1983, Volume: 18, Issue:3

    Topics: Adult; Blood Glucose; Feeding and Eating Disorders; Female; Growth Hormone; Hormones; Humans; Hyperp

1983
Decreased free fraction of serum thyroid hormones during carbohydrate overfeeding.
    Metabolism: clinical and experimental, 1984, Volume: 33, Issue:9

    Topics: Adult; Dietary Carbohydrates; Humans; Hyperphagia; Male; Prealbumin; Serum Albumin; Thyroid Hormones

1984
The role of hyperphagia and hypothyroidism in the development of the obese-hyperglycemic syndrome in mice (ob/ob).
    International journal of obesity, 1981, Volume: 5, Issue:4

    Topics: Animals; Diet; Feeding and Eating Disorders; Humans; Hyperglycemia; Hyperphagia; Hypothyroidism; Mal

1981
Enhanced thermogenesis during recovery from diet-induced weight gain in the rat.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: Animals; Body Composition; Body Temperature Regulation; Diet; Dietary Carbohydrates; Dietary Fats; E

1996
Increasing age impairs the thyroid hormone response to overfeeding.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1990, Volume: 194, Issue:3

    Topics: Adipose Tissue, Brown; Aging; Animals; Energy Intake; Hyperphagia; Iodide Peroxidase; Liver; Male; O

1990
Some metabolic effects of overeating in man.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:6

    Topics: Adult; Basal Metabolism; Blood Glucose; Energy Intake; Energy Metabolism; Erythrocytes; Feeding and

1986
Dynamics of recovery of body composition after overfeeding, food restriction or starvation of mature female rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:12

    Topics: Animals; Body Composition; Body Weight; Feeding and Eating Disorders; Female; Food Deprivation; Hype

1986
Energy intake, weight gain and fat deposition in rats fed flavored, nutritionally controlled diets in a multichoice ("cafeteria") design.
    The Journal of nutrition, 1985, Volume: 115, Issue:11

    Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Body Weight; Dietary Carbohydrates; Dietary Fa

1985