thyroxine has been researched along with Hormone-Dependent Neoplasms in 12 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effect of thyroxine treatment on tumor growth and metastases resulting from tumor implants on the hind feet of mice in two syngeneic systems." | 7.66 | Enhancing effect of thyroxine on tumor growth and metastases in syngeneic mouse tumor systems. ( Chiang, T; Deodhar, SD; Kumar, MS, 1979) |
| "The effects of growth hormone (GH) and/or cortisone and thyroxine (T4) treatment on the ultrastructure of the transplantable Swarm rat chondrosarcoma grown in hypophysectomized rats were studied." | 3.66 | Hormone responsiveness of a transplantable rat chondrosarcoma: III. ultrastructural evidence of in vivo hormone dependence. ( Lebovitz, HE; McCarty, KS; McCumbee, WD, 1981) |
| " Exogenous thyroxine (8 microgram/kg body weight) reversed the effects of PTU and actually shortened survival." | 3.66 | Increased survival of rats bearing Morris hepatoma 7800 after induction of hypothyroidism. ( Mishkin, S; Morris, HP; Narasimha Murthy, PV; Yalovsky, MA, 1979) |
| "We studied the effect of thyroxine treatment on tumor growth and metastases resulting from tumor implants on the hind feet of mice in two syngeneic systems." | 3.66 | Enhancing effect of thyroxine on tumor growth and metastases in syngeneic mouse tumor systems. ( Chiang, T; Deodhar, SD; Kumar, MS, 1979) |
| "Patients with thyroid cancer benefit from treatment with exogenous thyroid hormone for two reasons: it provides adequate levels of thyroid hormone to peripheral tissues, and it reduces the level of thyrotropin, which may be an important growth factor in patients with differentiated malignant neoplasms." | 1.27 | Thyroid suppression and medical ablation for differentiated thyroid cancer. ( Dunn, JT, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shinderman-Maman, E | 1 |
| Cohen, K | 1 |
| Weingarten, C | 1 |
| Nabriski, D | 1 |
| Twito, O | 1 |
| Baraf, L | 1 |
| Hercbergs, A | 1 |
| Davis, PJ | 1 |
| Werner, H | 1 |
| Ellis, M | 1 |
| Ashur-Fabian, O | 1 |
| Makaridze, T | 1 |
| Mardaleishvili, K | 1 |
| Sibilio, A | 1 |
| Ambrosio, R | 1 |
| Bonelli, C | 1 |
| De Stefano, MA | 1 |
| Torre, V | 1 |
| Dentice, M | 1 |
| Salvatore, D | 1 |
| Gupta, MK | 1 |
| Chiang, T | 2 |
| Deodhar, SD | 2 |
| Goodman, AD | 1 |
| Hoekstra, SJ | 1 |
| Marsh, PS | 1 |
| McCumbee, WD | 1 |
| Lebovitz, HE | 1 |
| McCarty, KS | 1 |
| Lupulescu, A | 1 |
| Roy, G | 1 |
| Nakatani, T | 1 |
| Goto, T | 1 |
| Fujimoto, N | 1 |
| Ito, A | 1 |
| Burnett, AK | 1 |
| Mishkin, S | 1 |
| Morris, HP | 1 |
| Yalovsky, MA | 1 |
| Narasimha Murthy, PV | 1 |
| Kumar, MS | 1 |
| Dunn, JT | 1 |
1 review available for thyroxine and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Deiodination in cancer growth: the role of type III deiodinase.
Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Induction; Gene Expression | 2012 |
11 other studies available for thyroxine and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
The thyroid hormone-αvβ3 integrin axis in ovarian cancer: regulation of gene transcription and MAPK-dependent proliferation.
Topics: Antibodies, Neutralizing; Cell Division; Cell Line, Tumor; Culture Media; Enzyme Activation; Extrace | 2016 |
Novelties in treatment approach of poly-neoplasias developed during thyroid pathologies.
Topics: Antidepressive Agents, Second-Generation; Breast Neoplasms; Dopamine; Female; Humans; Male; Mastecto | 2010 |
Specific triiodothyronine binding by tumor cells and spleen cells in a thyroid hormone dependent mouse tumor system.
Topics: Animals; Binding, Competitive; Cell Nucleus; Female; Fibrosarcoma; Mice; Mice, Inbred C57BL; Mitocho | 1981 |
Effects of hypothyroidism on the induction and growth of mammary cancer induced by 7,12-dimethylbenz(a)anthracene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Hypothyroidism; Mammary Neoplasms, E | 1980 |
Hormone responsiveness of a transplantable rat chondrosarcoma: III. ultrastructural evidence of in vivo hormone dependence.
Topics: Animals; Chondrosarcoma; Cortisone; Growth Hormone; Hypophysectomy; Male; Neoplasm Transplantation; | 1981 |
Hormonal regulation of epidermal tumor development.
Topics: Animals; Calcitonin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; DNA Replication; Estradiol; Ho | 1981 |
Effect of 17 beta-estradiol, retinoic acid and tamoxifen upon primary and transplanted thyroid tumor in B6C3F1 mice fed an iodine deficient diet.
Topics: Animals; Estradiol; Female; Iodine; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Trans | 1997 |
Thyroid hormone in 7,12-dimethylbenz(a)anthracene-induced leukemia in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Hematopoietic Stem Cells; Leu | 1979 |
Increased survival of rats bearing Morris hepatoma 7800 after induction of hypothyroidism.
Topics: Animals; Body Weight; Hypothyroidism; Liver Neoplasms, Experimental; Neoplasms, Hormone-Dependent; O | 1979 |
Enhancing effect of thyroxine on tumor growth and metastases in syngeneic mouse tumor systems.
Topics: Animals; Benz(a)Anthracenes; Female; Hyperthyroidism; Hypothyroidism; Mice; Mice, Inbred A; Mice, In | 1979 |
Thyroid suppression and medical ablation for differentiated thyroid cancer.
Topics: Adenocarcinoma; Carcinoma, Papillary; Humans; Iodine Radioisotopes; Neoplasms, Hormone-Dependent; Th | 1986 |