thyroxine has been researched along with Hodgkin Disease in 22 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an attempt to reduce the incidence of hypothyroidism following irradiation of the neck, we administered oral L-thyroxine in doses sufficient to suppress serum TSH to 20 patients receiving radiation therapy for Hodgkin's disease or other lymphomas." | 5.05 | Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction. ( Bantle, JP; Lee, CK; Levitt, SH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (68.18) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peiró, I | 1 |
| Palmero, R | 1 |
| Iglesias, P | 1 |
| Díez, JJ | 1 |
| Simó-Servat, A | 1 |
| Marín, JA | 1 |
| Jiménez, L | 1 |
| Domingo-Domenech, E | 1 |
| Mancho-Fora, N | 1 |
| Nadal, E | 1 |
| Villabona, C | 1 |
| Cella, L | 1 |
| Conson, M | 1 |
| Caterino, M | 1 |
| De Rosa, N | 1 |
| Liuzzi, R | 1 |
| Picardi, M | 1 |
| Grimaldi, F | 1 |
| Solla, R | 1 |
| Farella, A | 1 |
| Salvatore, M | 1 |
| Pacelli, R | 1 |
| Massimino, M | 1 |
| Gandola, L | 1 |
| Pignoli, E | 1 |
| Seregni, E | 1 |
| Marchianò, A | 1 |
| Pecori, E | 1 |
| Catania, S | 1 |
| Cefalo, G | 1 |
| Metzger, ML | 1 |
| Hudson, MM | 1 |
| Somes, GW | 1 |
| Shorr, RI | 1 |
| Li, CS | 1 |
| Krasin, MJ | 1 |
| Shelso, J | 1 |
| Pui, CH | 1 |
| Howard, SC | 1 |
| Pekić, B | 2 |
| Popović, M | 1 |
| Pavelić, K | 2 |
| Gabrilovac, J | 1 |
| Bratic-Mikes, V | 1 |
| Boranic, M | 1 |
| Shiriaev, SV | 1 |
| Zubovskiĭ, LG | 1 |
| Poliakov, VE | 1 |
| Holt, G | 1 |
| Galligan, J | 1 |
| Winship, J | 1 |
| Roeser, P | 1 |
| Mortimer, R | 1 |
| Constine, LS | 1 |
| Donaldson, SS | 1 |
| McDougall, IR | 2 |
| Cox, RS | 1 |
| Link, MP | 1 |
| Kaplan, HS | 1 |
| Devney, RB | 1 |
| Sklar, CA | 1 |
| Nesbit, ME | 1 |
| Kim, TH | 1 |
| Williamson, JF | 1 |
| Robison, LL | 1 |
| Ramsay, NK | 1 |
| Simbirtseva, LP | 1 |
| Iulbarisov, AV | 1 |
| Lapchenkov, VI | 1 |
| Borisova, LIa | 1 |
| Schimpff, SC | 1 |
| Diggs, CH | 1 |
| Wiswell, JG | 1 |
| Salvatore, PC | 1 |
| Wiernik, PH | 1 |
| Bayer, MF | 1 |
| Shafford, EA | 1 |
| Kingston, JE | 1 |
| Healy, JC | 1 |
| Webb, JA | 1 |
| Plowman, PN | 1 |
| Reznek, RH | 1 |
| Serrano, JC | 1 |
| Contreras, K | 1 |
| Insausti, L | 1 |
| Figueroa, L | 1 |
| Acquatella, G | 1 |
| Worm, AM | 2 |
| Brinckmeyer, LM | 2 |
| Nissen, NI | 2 |
| Peerboom, PF | 1 |
| Hassink, EA | 1 |
| Melkert, R | 1 |
| DeWit, L | 1 |
| Nooijen, WJ | 1 |
| Bruning, PF | 1 |
| Morgan, GW | 1 |
| Freeman, AP | 1 |
| McLean, RG | 1 |
| Jarvie, BH | 1 |
| Giles, RW | 1 |
| Bantle, JP | 1 |
| Lee, CK | 1 |
| Levitt, SH | 1 |
| Glatstein, E | 1 |
| McHardy-Young, S | 1 |
| Brast, N | 1 |
| Eltringham, JR | 1 |
| Kriss, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protection From Iatrogenic Hypothyroidism Patients With MBL and Pediatric Patients With HL and Non-HL Needing Radiotherapy on Thyroid Site[NCT05316922] | Phase 3 | 68 participants (Anticipated) | Interventional | 2021-12-13 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thyroxine and Hodgkin Disease
| Article | Year |
|---|---|
Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction.
Topics: Adolescent; Adult; Female; Hodgkin Disease; Humans; Hypothyroidism; Lymphoma; Male; Middle Aged; Nec | 1985 |
21 other studies available for thyroxine and Hodgkin Disease
| Article | Year |
|---|---|
Thyroid dysfunction induced by nivolumab: searching for disease patterns and outcomes.
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Carcinoma, Non-Small-Cell Lung; Female; Hodgkin D | 2019 |
Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; | 2012 |
TSH suppression as a possible means of protection against hypothyroidism after irradiation for childhood Hodgkins lymphoma.
Topics: Adolescent; Child; Disease-Free Survival; Female; Hodgkin Disease; Humans; Hypothyroidism; Male; Rad | 2011 |
White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin's lymphoma.
Topics: Adolescent; Adult; Black People; Child; Child, Preschool; Female; Hodgkin Disease; Hormone Replaceme | 2006 |
[Changes in hormone concentrations in the blood of patients with malignant diseases of the blood].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Growth Hormone; Hodgkin Disease; Hormones; Humans; Hydroco | 1984 |
Hormonal changes in patients with haematological malignancies.
Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho | 1981 |
[Hormones and ferritin in children with lymphogranulomatosis].
Topics: Adrenocorticotropic Hormone; Child; Ferritins; Hodgkin Disease; Humans; Hydrocortisone; Insulin; Thy | 1982 |
Serum thyroglobulin after mantle irradiation for Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Child; Female; Hodgkin Disease; Humans; Male; Middle Aged; Thyroglobulin; T | 1983 |
Thyroid dysfunction after radiotherapy in children with Hodgkin's disease.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Combined Modality Therapy; Dose-Response Relations | 1984 |
Serial thyroid function measurements in children with Hodgkin disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali | 1984 |
[Radioimmunological determination of thyrotropic hormone, triiodothyronine and thyroxine in lymphogranulomatosis during radiation and combined therapy].
Topics: Adolescent; Adult; Hodgkin Disease; Humans; Middle Aged; Neoplasm Staging; Radioimmunoassay; Thyrotr | 1983 |
Radiation-related thyroid dysfunction: implications for the treatment of Hodgkin's disease.
Topics: Adolescent; Adult; Child; Drug-Related Side Effects and Adverse Reactions; Follow-Up Studies; Head a | 1980 |
Radioimmunoassay of free thyroxine in serum: comparison with clinical findings and results of conventional thyroid-function tests.
Topics: Hodgkin Disease; Humans; Hyperthyroidism; Hypothyroidism; Radioimmunoassay; Reference Values; Thyroi | 1980 |
Thyroid nodular disease after radiotherapy to the neck for childhood Hodgkin's disease.
Topics: Adolescent; Biopsy, Needle; Child; Child, Preschool; Dose-Response Relationship, Radiation; Female; | 1999 |
[Thyroid complications in Hodgkin's disease patients treated with radiotherapy and chemotherapy].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Male; Thyroid Diseases; | 1999 |
[Thyroid function in malignant lymphoma].
Topics: Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, N | 1977 |
Thyroid function in malignant lymphoma.
Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; | 1977 |
Thyroid function 10-18 years after mantle field irradiation for Hodgkin's disease.
Topics: Adult; Age Factors; Aged; Female; Follow-Up Studies; Hodgkin Disease; Humans; Hypothyroidism; Male; | 1992 |
Late cardiac, thyroid, and pulmonary sequelae of mantle radiotherapy for Hodgkin's disease.
Topics: Adult; Carbon Monoxide; Electrocardiography; Forced Expiratory Volume; Heart; Hodgkin Disease; Human | 1985 |
Alterations in serum thyrotropin (TSH) and thyroid function following radiotherapy in patients with malignant lymphoma.
Topics: Adolescent; Adult; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Hypothyroidism; Ion Exc | 1971 |
[Diseases of the thyroid gland].
Topics: Daunorubicin; Goiter; Graves Disease; Hematologic Diseases; Hodgkin Disease; Humans; Hyperthyroidism | 1967 |