thyroxine and Heroin Dependence
thyroxine has been researched along with Heroin Dependence in 8 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Heroin Dependence: Strong dependence or addiction, both physiological and emotional, upon HEROIN.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heroin addiction is a chronic, complex disease, often accompanied by other concomitant disorders, which may encumber effective prevention and treatment." | 1.40 | Serum proteomic analysis reveals high frequency of haptoglobin deficiency and elevated thyroxine level in heroin addicts. ( Liu, ZM; Pu, XP; Qu, Z; Shi, WL; Yan, SY; Zhao, X; Zhou, BY, 2014) |
| "The severity of opioid abuse and of withdrawal symptoms was assessed." | 1.35 | Alterations in pituitary-thyroid axis function among opioid-dependent subjects after acute and protracted abstinence. ( Chi, Y; Du, WJ; Guo, S; Jiang, ZN; Liu, ZQ; Luo, XN; Sheng, LX; Smith, AK; Tang, YL; Xiao, L; Zhang, GF; Zhang, HX, 2009) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhou, BY | 1 |
| Yan, SY | 1 |
| Shi, WL | 1 |
| Qu, Z | 1 |
| Zhao, X | 1 |
| Liu, ZM | 1 |
| Pu, XP | 1 |
| Zhang, GF | 1 |
| Tang, YL | 1 |
| Smith, AK | 1 |
| Liu, ZQ | 1 |
| Sheng, LX | 1 |
| Chi, Y | 1 |
| Du, WJ | 1 |
| Guo, S | 1 |
| Jiang, ZN | 1 |
| Xiao, L | 1 |
| Zhang, HX | 1 |
| Luo, XN | 1 |
| Ilias, I | 1 |
| Kakoulas, I | 1 |
| Christakopoulou, I | 1 |
| Katsadoros, K | 1 |
| Chan, V | 1 |
| Wang, C | 1 |
| Yeung, RT | 1 |
| Ho, WK | 1 |
| Wen, HL | 1 |
| Fung, KP | 1 |
| Ng, YH | 1 |
| Au, KK | 1 |
| Ma, L | 1 |
| Afrasiabi, MA | 1 |
| Flomm, M | 1 |
| Friedlander, H | 1 |
| Valenta, LJ | 1 |
| Bastomsky, CH | 1 |
| Dent, RR | 1 |
| Tolis, G | 1 |
| Webster, JB | 1 |
| Coupal, JJ | 1 |
| Cushman, P | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-treated Chronic Pain Patients: A Pilot Study.[NCT00398034] | Phase 2 | 0 participants (Actual) | Interventional | 2006-10-30 | Withdrawn (stopped due to The original PI (David Siegel) Left the VA) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
8 other studies available for thyroxine and Heroin Dependence
| Article | Year |
|---|---|
Serum proteomic analysis reveals high frequency of haptoglobin deficiency and elevated thyroxine level in heroin addicts.
Topics: Adult; Female; Haptoglobins; Heroin Dependence; Humans; Male; Proteomics; Thyrotropin; Thyroxine; Tr | 2014 |
Alterations in pituitary-thyroid axis function among opioid-dependent subjects after acute and protracted abstinence.
Topics: Adult; Female; Follow-Up Studies; Heroin; Heroin Dependence; Humans; Male; Narcotics; Pituitary Glan | 2009 |
Thyroid function of former opioid addicts on naltrexone treatment.
Topics: Adult; Female; Heroin Dependence; Humans; Interleukin-6; Male; Naltrexone; Narcotic Antagonists; Thy | 2001 |
Effects of heroin addiction on thyrotrophin, thyroid hormones and porlactin secretion in men.
Topics: Adult; Heroin Dependence; Humans; Male; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyro | 1979 |
Comparison of plasma hormonal levels between heroin-addicted and normal subjects.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Cholesterol; Cyclic AMP; Heroin Depende | 1977 |
Endocrine studies in heroin addicts.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Estradiol; Female; Follicle Stimulating Hormone; Gro | 1979 |
Elevated serum concentrations of thyroxine-binding globulin and caeruloplasmin in methadone-maintained patients.
Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Ceruloplasmin; | 1977 |
Increased serum thyroxine levels in euthyroid narcotic addicts.
Topics: Adult; District of Columbia; Female; Heroin Dependence; Humans; Male; Methadone; New York City; Subs | 1973 |