thyroxine has been researched along with Hepatic Encephalopathy in 16 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent data from animal studies suggest that induced hypothyroidism prevents the hyperdynamic circulation in portal vein ligated rats, liver cirrhosis in rats chronically treated with thioacetamide (TAA), and immune-mediated acute liver injury induced in mice by concanavalin A." | 7.70 | Hypothyroidism minimizes liver damage and improves survival in rats with thioacetamide induced fulminant hepatic failure. ( Aeed, H; Avni, Y; Bruck, R; Halpern, Z; Matas, Z; Oren, R; Papa, M; Shirin, H; Zaidel, L, 1998) |
| "Grades 3 to 4 hepatic encephalopathy (advanced HE), also termed brain failure, is an organ failure that defines acute-on-chronic liver failure." | 5.91 | Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort. ( Bajaj, JS; Fagan, A; Garcia-Tsao, G; Kamath, PS; Lai, JC; McGeorge, S; O'Leary, JG; Reddy, KR; Subramanian, RM; Tandon, P; Thacker, LR; Thuluvath, P; Vargas, HE; Wong, F, 2023) |
| "15 consecutive patients with hepatic encephalopathy secondary to non-alcoholic cirrhosis (8 males and 7 females, age 37-75 years) and 33 non-alcoholic cirrhotic patients without encephalopathy (22 males and 11 females, age 36-74 years) were investigated." | 5.32 | Low serum total thyroxine and free triiodothyronine in patients with hepatic encephalopathy due to non-alcoholic cirrhosis. ( Kaya, A; Kayacetin, E; Kisakol, G, 2003) |
| "Recent data from animal studies suggest that induced hypothyroidism prevents the hyperdynamic circulation in portal vein ligated rats, liver cirrhosis in rats chronically treated with thioacetamide (TAA), and immune-mediated acute liver injury induced in mice by concanavalin A." | 3.70 | Hypothyroidism minimizes liver damage and improves survival in rats with thioacetamide induced fulminant hepatic failure. ( Aeed, H; Avni, Y; Bruck, R; Halpern, Z; Matas, Z; Oren, R; Papa, M; Shirin, H; Zaidel, L, 1998) |
| " On the diagnosis of hypothalamic hypothyroidism, she was treated with levothyroxine sodium." | 3.68 | Portal-systemic encephalopathy and hypothalamic hypothyroidism: effect of thyroid hormone on ammonia metabolism. ( Hitoshi, S; Sakuta, M; Terao, Y, 1993) |
| "To evaluate thyroid function in 19 patients with fulminant hepatitis (FH), we have measured total and free 3,5,3'-triiodothyronine (T3) and thyroxine (T4), 3,3',5'-triiodothyronine (reverse T3, rT3), thyroid-stimulating hormone (TSH) and thyroxin-binding globulin (TBG) in patients with FH, compared with those of 80 patients with other various liver diseases and of 10 healthy controls." | 3.67 | Serum thyroid hormone levels in patients with fulminant hepatitis: usefulness of rT3 and the rT3/T3 ratio as prognostic indices. ( Kano, T; Kojima, T; Muto, Y; Takahashi, T, 1987) |
| " Twenty patients suffering from severe non-endocrine diseases (septicaemia, fulminant hepatic and renal failure, acute pancreatitis, polytrauma, cerebral haemorrhage) were found to have serum thyroxine levels in the hypothyroid range (less than 4 micrograms/dl)." | 3.66 | Pituitary-thyroid dysfunction in severe non-thyroidal disease: "low-T4 syndrome". ( Bratusch-Marrain, P; Grubeck-Loebenstein, B; Kleinberger, G; Vierhapper, H; Waldhäusl, W, 1982) |
| "Despite aggressive treatment of hepatic encephalopathy, there was no clinical improvement." | 2.41 | Primary hypothyroidism masquerading as hepatic encephalopathy: case report and review of the literature. ( Jones, MP; Pilger, P; Thobe, N, 2000) |
| "Grades 3 to 4 hepatic encephalopathy (advanced HE), also termed brain failure, is an organ failure that defines acute-on-chronic liver failure." | 1.91 | Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort. ( Bajaj, JS; Fagan, A; Garcia-Tsao, G; Kamath, PS; Lai, JC; McGeorge, S; O'Leary, JG; Reddy, KR; Subramanian, RM; Tandon, P; Thacker, LR; Thuluvath, P; Vargas, HE; Wong, F, 2023) |
| "15 consecutive patients with hepatic encephalopathy secondary to non-alcoholic cirrhosis (8 males and 7 females, age 37-75 years) and 33 non-alcoholic cirrhotic patients without encephalopathy (22 males and 11 females, age 36-74 years) were investigated." | 1.32 | Low serum total thyroxine and free triiodothyronine in patients with hepatic encephalopathy due to non-alcoholic cirrhosis. ( Kaya, A; Kayacetin, E; Kisakol, G, 2003) |
| "Patients with hepatic encephalopathy due to non-alcoholic cirrhosis were studied at Erciyes University Hospital, Kayseri, Turkey, between August 1990 and October 1991." | 1.29 | Thyroid function tests in non-alcoholic cirrhotic patients with hepatic encephalopathy. ( Güven, K; Kelestimur, F; Yücesoy, M, 1993) |
| "Similarly, the presence or absence of hepatic encephalopathy determined, and/or reflected, at least in part, the type of response observed." | 1.27 | Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease. ( Gavaler, JS; Sanghvi, A; Schade, RR; Tarter, R; Van Thiel, DH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Bajaj, JS | 1 |
| Tandon, P | 1 |
| O'Leary, JG | 1 |
| Reddy, KR | 1 |
| Garcia-Tsao, G | 1 |
| Thuluvath, P | 1 |
| Lai, JC | 1 |
| Subramanian, RM | 1 |
| Vargas, HE | 1 |
| Wong, F | 1 |
| Fagan, A | 1 |
| McGeorge, S | 1 |
| Thacker, LR | 1 |
| Kamath, PS | 1 |
| Díaz-Fontenla, F | 1 |
| Castillo-Pradillo, M | 1 |
| Díaz-Gómez, A | 1 |
| Ibañez-Samaniego, L | 1 |
| Gancedo, P | 1 |
| Guzmán-de-Villoria, JA | 1 |
| Fernández-García, P | 1 |
| Bañares-Cañizares, R | 1 |
| García-Martínez, R | 1 |
| Redkar, N | 1 |
| Bendle, M | 1 |
| Maidapwad, V | 1 |
| Chavan, R | 1 |
| Shriwastav, R | 1 |
| Kayacetin, E | 1 |
| Kisakol, G | 1 |
| Kaya, A | 1 |
| Rink, C | 1 |
| Siersleben, U | 1 |
| Haerting, J | 1 |
| Klaua, M | 1 |
| Mertens, E | 1 |
| Bratusch-Marrain, P | 1 |
| Vierhapper, H | 1 |
| Grubeck-Loebenstein, B | 1 |
| Waldhäusl, W | 1 |
| Kleinberger, G | 1 |
| Güven, K | 1 |
| Kelestimur, F | 1 |
| Yücesoy, M | 1 |
| Hitoshi, S | 1 |
| Terao, Y | 1 |
| Sakuta, M | 1 |
| Bruck, R | 1 |
| Oren, R | 1 |
| Shirin, H | 1 |
| Aeed, H | 1 |
| Papa, M | 1 |
| Matas, Z | 1 |
| Zaidel, L | 1 |
| Avni, Y | 1 |
| Halpern, Z | 1 |
| Caregaro, L | 1 |
| Alberino, F | 1 |
| Amodio, P | 1 |
| Merkel, C | 1 |
| Angeli, P | 1 |
| Plebani, M | 1 |
| Gatta, A | 1 |
| Thobe, N | 1 |
| Pilger, P | 1 |
| Jones, MP | 1 |
| Schlienger, JL | 1 |
| Hasselmann, M | 1 |
| Imler, M | 1 |
| Biersack, HJ | 1 |
| Raabe, W | 1 |
| Rommelsheim, K | 1 |
| Rohner, HG | 1 |
| Fuchs, HJ | 1 |
| Winkler, C | 1 |
| Van Thiel, DH | 1 |
| Tarter, R | 1 |
| Gavaler, JS | 1 |
| Schade, RR | 1 |
| Sanghvi, A | 1 |
| Kano, T | 1 |
| Kojima, T | 1 |
| Takahashi, T | 1 |
| Muto, Y | 1 |
| Bregengård, C | 1 |
| Kirkegaard, C | 1 |
| Faber, J | 1 |
| Poulsen, S | 1 |
| Siersbaek-Nielsen, K | 1 |
| Friis, T | 1 |
1 review available for thyroxine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Primary hypothyroidism masquerading as hepatic encephalopathy: case report and review of the literature.
Topics: Aged; Diagnosis, Differential; Female; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Hypothy | 2000 |
15 other studies available for thyroxine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort.
Topics: Fibrosis; Hepatic Encephalopathy; Humans; Inpatients; Liver Cirrhosis; Prospective Studies; Thyroxin | 2023 |
Refractory hepatic encephalopathy in a patient with hypothyroidism: Another element in ammonia metabolism.
Topics: Adrenergic beta-Antagonists; Alcoholism; Ammonia; Antithyroid Agents; Brain; Carbimazole; Diagnosis, | 2017 |
Hepatic encephalopathy masking myxedema coma.
Topics: Aged; Coma; Diagnosis, Differential; Glasgow Coma Scale; Hepatic Encephalopathy; Humans; Hydrocortis | 2012 |
Low serum total thyroxine and free triiodothyronine in patients with hepatic encephalopathy due to non-alcoholic cirrhosis.
Topics: Adult; Aged; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Prothrombin | 2003 |
[The T3 syndrome in patients with liver cirrhosis].
Topics: Collateral Circulation; Hepatic Encephalopathy; Humans; Liver Circulation; Liver Cirrhosis; Radioimm | 1982 |
Pituitary-thyroid dysfunction in severe non-thyroidal disease: "low-T4 syndrome".
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aged; Critical Care; Female; Hepatic Encephal | 1982 |
Thyroid function tests in non-alcoholic cirrhotic patients with hepatic encephalopathy.
Topics: Adult; Aged; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Prognosis; | 1993 |
Portal-systemic encephalopathy and hypothalamic hypothyroidism: effect of thyroid hormone on ammonia metabolism.
Topics: Ammonia; Euthyroid Sick Syndromes; Female; Hepatic Encephalopathy; Humans; Hypothalamic Diseases; Hy | 1993 |
Hypothyroidism minimizes liver damage and improves survival in rats with thioacetamide induced fulminant hepatic failure.
Topics: Ammonia; Animals; Cytokines; Hepatic Encephalopathy; Hypothyroidism; Liver; Male; Malondialdehyde; R | 1998 |
Nutritional and prognostic significance of serum hypothyroxinemia in hospitalized patients with liver cirrhosis.
Topics: Adult; Aged; Ascites; Blood Proteins; Female; Hepatic Encephalopathy; Hepatitis, Viral, Human; Human | 1998 |
Possible role of hyperammonaemia and/or of portosystemic shunts on the variability of the TSH response to TRH in cirrhotic patients.
Topics: Adult; Aged; Ammonia; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver Function Tests; | 1978 |
[Thyroid hormones and thyrotropin in liver and kidney insufficiency].
Topics: Hepatic Encephalopathy; Humans; Kidney Failure, Chronic; Liver; Thyroid Hormones; Thyrotropin; Thyro | 1976 |
Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease.
Topics: Carcinoma, Hepatocellular; Growth Hormone; Hepatic Encephalopathy; Humans; Liver Diseases; Liver Neo | 1986 |
Serum thyroid hormone levels in patients with fulminant hepatitis: usefulness of rT3 and the rT3/T3 ratio as prognostic indices.
Topics: Adult; Aged; Female; Hepatic Encephalopathy; Hepatitis; Humans; Male; Methionine; Middle Aged; Progn | 1987 |
The influence of free fatty acids on the free fraction of thyroid hormones in serum as estimated by ultrafiltration.
Topics: Cerebrovascular Disorders; Fatty Acids, Nonesterified; Hepatic Encephalopathy; Humans; Kidney Failur | 1987 |