Page last updated: 2024-11-06

thyroxine and Hemorrhage

thyroxine has been researched along with Hemorrhage in 24 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Hemorrhage: Bleeding or escape of blood from a vessel.

Research Excerpts

ExcerptRelevanceReference
"Our study revealed no evidence that L-thyroxine could increase bleeding risk in patients receiving VKAs."7.85Assessment of the Impact of L-Thyroxine Therapy on Bleeding Risk in Patients Receiving Vitamin K Antagonists. ( Barres, A; Batisse, M; Dutheil, F; Malhomme, R; Moustafa, F; Pereira, B; Saint-Denis, J; Schmidt, J, 2017)
" The effect of hyperthyroxinemia on TAFI was studied in healthy volunteers who were randomised to receive levothyroxine or no medication for 14 days in a crossover design."5.17Thrombin-activatable fibrinolysis inhibitor in hypothyroidism and hyperthyroxinaemia. ( Brandjes, DP; Büller, HR; Gerdes, VE; Meijers, JC; Squizzato, A; Stuijver, DJ; van Zaane, B; Verkleij, CJ, 2013)
"Our study revealed no evidence that L-thyroxine could increase bleeding risk in patients receiving VKAs."3.85Assessment of the Impact of L-Thyroxine Therapy on Bleeding Risk in Patients Receiving Vitamin K Antagonists. ( Barres, A; Batisse, M; Dutheil, F; Malhomme, R; Moustafa, F; Pereira, B; Saint-Denis, J; Schmidt, J, 2017)
"Myxoedema coma is a rare emergency needing prompt recognition and urgent treatment before diagnostic confirmation."2.36Myxoedema coma. A review. ( Khaleeli, A, 1978)
"Hypothyroidism was diagnosed in a 62-year-old woman with poorly controlled primary open-angle glaucoma, including a disc hemorrhage and a documented arcuate scotoma."1.28Reversal of poorly controlled glaucoma on diagnosis and treatment of hypothyroidism. ( Allen, LH; Smith, KD; Tevaarwerk, GJ, 1992)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's1 (4.17)18.2507
2000's3 (12.50)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moustafa, F1
Malhomme, R1
Pereira, B1
Barres, A1
Saint-Denis, J1
Dutheil, F1
Batisse, M1
Schmidt, J1
Oliveira, GN1
Dinis, I1
Noruegas, MJ1
Mirante, A1
Ferreira-González, L1
Trigás-Ferrín, M1
Rubin, EP1
Sesma, P1
Pincus, D1
Gomes, T1
Hellings, C1
Zheng, H1
Paterson, JM1
Mamdani, MM1
Juurlink, DN1
Verkleij, CJ1
Stuijver, DJ1
van Zaane, B2
Squizzato, A2
Brandjes, DP2
Büller, HR1
Meijers, JC1
Gerdes, VE2
Paul, R1
GILBERT, C1
GILLMAN, J1
TATA, JR1
LANG, S1
KEEFER, FJ1
Bowles, KM1
Turner, GE1
Wimperis, JZ1
Manfredi, E1
Kawamura, S1
Kishino, B1
Tajima, K1
Mashita, K1
Tarui, S1
Gorewit, RC1
Georgieva, SA1
Golovchenko, VM1
Gladilin, GP1
Kirichuk, VF1
Tokaeva, LK1
Khaleeli, A1
Smith, KD1
Tevaarwerk, GJ1
Allen, LH1
Dalton, RG1
Dewar, MS1
Savidge, GF1
Kernoff, PB1
Matthews, KB1
Greaves, M1
Preston, FE1
Wilson, WW1
Luton, JP1
Lange, MJ1
Green, D1
Smith, NJ1
Taylor, AL1
Finster, JL1
Raskin, P1
Field, JB1
Mintz, DH1
Johansson, H1
Jönsson, LE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Registry of Patient With Antithrombotic Agents Admitted to an Emergency[NCT02706080]10 participants (Anticipated)Observational2014-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for thyroxine and Hemorrhage

ArticleYear
Hypothyroidism and acquired von Willebrand's syndrome: a systematic review.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2008, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aged; Bleeding Time; Child; Deamino Arginine Vasopressin; Disease Susceptibility;

2008
Myxoedema coma. A review.
    Pahlavi medical journal, 1978, Volume: 9, Issue:2

    Topics: Acute Kidney Injury; Coma; Diagnosis, Differential; Hemorrhage; Humans; Hypoglycemia; Hyponatremia;

1978
Hemophilia. Current concepts in management.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Analgesics; Antifibrinolytic Agents; Blood Transfusion; Cardiovascul

1972

Trials

1 trial available for thyroxine and Hemorrhage

ArticleYear
Thrombin-activatable fibrinolysis inhibitor in hypothyroidism and hyperthyroxinaemia.
    Thrombosis and haemostasis, 2013, Volume: 109, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation; Carboxypeptidase B2; Cross-Over Studies; Female;

2013

Other Studies

20 other studies available for thyroxine and Hemorrhage

ArticleYear
Assessment of the Impact of L-Thyroxine Therapy on Bleeding Risk in Patients Receiving Vitamin K Antagonists.
    Clinical drug investigation, 2017, Volume: 37, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Female; Fibrinolytic Agents; Hemorrhage; Humans; Hypertensi

2017
A rare cause of neonatal persistent jaundice.
    BMJ case reports, 2017, Dec-22, Volume: 2017

    Topics: Adrenal Glands; Adrenal Insufficiency; Anti-Inflammatory Agents; Cytomegalovirus Infections; Diabete

2017
Pituitary apoplexy after myocardial perfusion scintigraphy.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Adenoma; Aged; Angina, Unstable; Anticoagulants; Cardiac Pacing, Artificial; Dipyridamole; Female; H

2012
A population-based assessment of the drug interaction between levothyroxine and warfarin.
    Clinical pharmacology and therapeutics, 2012, Volume: 92, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Case-Control Studies; Cohort Studies; Drug Interactions; Fe

2012
[Bleeding problems of a patient with hypothyroidism].
    Duodecim; laaketieteellinen aikakauskirja, 2002, Volume: 118, Issue:13

    Topics: Aged; Anemia; Anticoagulants; Antifungal Agents; Atrial Fibrillation; Drug Interactions; Ecchymosis;

2002
The role of the adrenal and thyroid in promoting bleeding in hypophysectomized baboons (Papio ursinus).
    Endocrinology, 1956, Volume: 58, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Estrogens; Female; Hemorrhage; Humans; Papio; Papio ursinus; T

1956
Enzymic deiodination of L-thyroxine and 3:5:3'-triiodo-l-thyronine; intracellular localization of deiodinase in rat brain and skeletal muscle.
    Biochimica et biophysica acta, 1958, Volume: 28, Issue:1

    Topics: Amino Acids, Aromatic; Animals; Brain; Hemorrhage; Iodide Peroxidase; Muscle, Skeletal; Muscles; Rat

1958
Thyroid function and peripheral thyroxine metabolism after hemorrhage in the rat.
    The American journal of physiology, 1961, Volume: 200

    Topics: Animals; Hemorrhage; Rats; Thyroid Function Tests; Thyroid Gland; Thyroxine; Viscera

1961
SHEEHAN'S SYNDROME: A CASE REPORT.
    Alaska medicine, 1964, Volume: 6

    Topics: Diagnosis; Female; Hemorrhage; Humans; Hydrocortisone; Hypopituitarism; Inuit; Postpartum Hemorrhage

1964
Resolution of chronic severe refractory thrombocytopenia after treatment of hypothyroidism.
    Journal of clinical pathology, 2004, Volume: 57, Issue:9

    Topics: Chronic Disease; Female; Hemorrhage; Humans; Hypothyroidism; Middle Aged; Platelet Count; Thrombocyt

2004
Elevated serum thyroglobulin as a manifestation of acute haemorrhage into the thyroid gland.
    Clinical endocrinology, 1984, Volume: 20, Issue:2

    Topics: Acute Disease; Adult; Aged; Female; Hemorrhage; Humans; Male; Middle Aged; Thyroglobulin; Thyroid Di

1984
Pituitary and thyroid hormone responses of heifers after ferulic acid administration.
    Journal of dairy science, 1983, Volume: 66, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; Cholagogues and Choleretics; Cinnamates; Coumaric Acids; Ethanol;

1983
[Significance of adrenaline and thyroxine in the development of the thrombohemorrhagic syndrome].
    Problemy gematologii i perelivaniia krovi, 1980, Volume: 25, Issue:8

    Topics: Animals; Blood Coagulation; Epinephrine; Fibrinolysis; Hemorrhage; Rabbits; Syndrome; Thrombosis; Th

1980
Reversal of poorly controlled glaucoma on diagnosis and treatment of hypothyroidism.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1992, Volume: 27, Issue:7

    Topics: Female; Fundus Oculi; Glaucoma, Open-Angle; Hemorrhage; Humans; Hypothyroidism; Intraocular Pressure

1992
Hypothyroidism as a cause of acquired von Willebrand's disease.
    Lancet (London, England), 1987, May-02, Volume: 1, Issue:8540

    Topics: Adolescent; Adult; Blood Coagulation Tests; Female; Hemorrhage; Humans; Hypothyroidism; Middle Aged;

1987
Thyroid disease and some complications.
    Annals of the Royal College of Surgeons of England, 1973, Volume: 53, Issue:1

    Topics: Antithyroid Agents; Asphyxia; Goiter; Goiter, Nodular; Hemorrhage; Humans; Hypothyroidism; Recurrenc

1973
[Unchecked thyroid insufficiencies].
    La Presse medicale, 1969, Jun-25, Volume: 77, Issue:31

    Topics: Aged; Anuria; Coma; Cortisone; Female; Heating; Hemorrhage; Humans; Hypoglycemia; Hypopituitarism; H

1969
Thyroid swellings.
    The Practitioner, 1974, Volume: 212, Issue:1268

    Topics: Blood Cell Count; Deglutition Disorders; Female; Goiter; Hemorrhage; Humans; Hyperthyroidism; Lipoma

1974
Pituitary apoplexy in acromegaly.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabe

1968
Experimental studies on thyroid-adrenal interrelationships in rats.
    Acta chirurgica Scandinavica, 1968, Volume: 134, Issue:2

    Topics: Adrenal Glands; Animals; Edema; Hemorrhage; Hyperemia; Necrosis; Propylthiouracil; Rats; Thyroxine

1968