thyroxine has been researched along with Heart Failure, Systolic in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Heart Failure, Systolic: Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subclinical hypothyroidism is a common condition in patients with heart failure and is defined as elevated serum thyroid hormone (TSH) with normal circulating free thyroxine (FT4)." | 9.30 | Efficacy and safety of levothyroxine (L-T4) replacement on the exercise capability in chronic systolic heart failure patients with subclinical hypothyroidism: Study protocol for a multi-center, open label, randomized, parallel group trial (ThyroHeart-CHF) ( An, SM; Chen, J; Liu, YP; Tang, YD; Tian, J; Wang, JJ; Wang, SY; Wang, WY; Yang, M; Zhang, K; Zhang, X; Zhao, Y; Zheng, JL, 2019) |
| "Subclinical hypothyroidism is a common condition in patients with heart failure and is defined as elevated serum thyroid hormone (TSH) with normal circulating free thyroxine (FT4)." | 5.30 | Efficacy and safety of levothyroxine (L-T4) replacement on the exercise capability in chronic systolic heart failure patients with subclinical hypothyroidism: Study protocol for a multi-center, open label, randomized, parallel group trial (ThyroHeart-CHF) ( An, SM; Chen, J; Liu, YP; Tang, YD; Tian, J; Wang, JJ; Wang, SY; Wang, WY; Yang, M; Zhang, K; Zhang, X; Zhao, Y; Zheng, JL, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Wang, WY | 1 |
| Zhang, K | 1 |
| Tian, J | 1 |
| Zheng, JL | 1 |
| Chen, J | 1 |
| An, SM | 1 |
| Wang, SY | 1 |
| Liu, YP | 1 |
| Zhao, Y | 1 |
| Wang, JJ | 1 |
| Yang, M | 1 |
| Tang, YD | 1 |
| Passino, C | 1 |
| Pingitore, A | 1 |
| Landi, P | 1 |
| Fontana, M | 1 |
| Zyw, L | 1 |
| Clerico, A | 1 |
| Emdin, M | 1 |
| Iervasi, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Levothyroxine (L-T4) Replacement on Exercise Capability in Chronic Systolic Heart Failure Patients With Subclinical Hypothyroidism: A 24-week, Multi-center, Open Label, Randomized, Parallel Group Trial[NCT03096613] | Phase 4 | 124 participants (Anticipated) | Interventional | 2017-04-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thyroxine and Heart Failure, Systolic
| Article | Year |
|---|---|
Efficacy and safety of levothyroxine (L-T4) replacement on the exercise capability in chronic systolic heart failure patients with subclinical hypothyroidism: Study protocol for a multi-center, open label, randomized, parallel group trial (ThyroHeart-CHF)
Topics: Asymptomatic Diseases; China; Chronic Disease; Exercise Tolerance; Heart Failure, Systolic; Hormone | 2019 |
1 other study available for thyroxine and Heart Failure, Systolic
| Article | Year |
|---|---|
Prognostic value of combined measurement of brain natriuretic peptide and triiodothyronine in heart failure.
Topics: Aged; Biomarkers; Female; Follow-Up Studies; Heart Failure, Systolic; Humans; Male; Middle Aged; Mul | 2009 |