Page last updated: 2024-11-06

thyroxine and Heart Diseases

thyroxine has been researched along with Heart Diseases in 80 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.

Research Excerpts

ExcerptRelevanceReference
"This study sought to examine the effects of levothyroxine treatment in patients with subclinical hypothyroidism and heart disease."7.83Long-Term Outcome in Levothyroxine Treated Patients With Subclinical Hypothyroidism and Concomitant Heart Disease. ( Andersen, MN; Faber, J; Gislason, GH; Kristensen, SL; Madsen, JC; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2016)
"Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some cardiac hypertrophy models."7.76Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. ( Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL, 2010)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."7.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Amioradone-induced hyperthyroidism is a common complication of amiodarone therapy."7.72[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131]. ( Arlot, S; Hermida, JS; Jarry, G; Moullart, V; Rey, JL; Schvartz, C; Tcheng, E, 2004)
"In some patients with hypothyroidism, symptoms of ill health persist despite thyroxine treatment."4.81Dissatisfaction with thyroxine therapy - could the patients be right? ( Walsh, JP, 2002)
"Subclinical hyperthyroidism is defined by a subnormal serum thyroidstimulating hormone (TSH) level with normal free thyroxine (FT4) and free triiodothyronine (FT3) levels."3.96Role of Subclinical Iatrogenic Hyperthyroidism in the Setting of Heart Disease and Arrhythmic Burden. ( De Luca, G; Di Stolfo, G; Maggio, A; Massaro, R; Mastroianno, S; Pacilli, M; Potenza, DR; Russo, A, 2020)
"This study sought to examine the effects of levothyroxine treatment in patients with subclinical hypothyroidism and heart disease."3.83Long-Term Outcome in Levothyroxine Treated Patients With Subclinical Hypothyroidism and Concomitant Heart Disease. ( Andersen, MN; Faber, J; Gislason, GH; Kristensen, SL; Madsen, JC; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2016)
"We sought to investigate right ventricular (RV) function and deformation assessed by three-dimensional echocardiography (3DE) and speckle tracking in patients with subclinical hypothyroidism (SHT), and to evaluate the influence of levothyroxine (L-T₄) therapy on RV remodeling."3.80Right ventricular and right atrial function and deformation in patients with subclinical hypothyroidism: a two- and three-dimensional echocardiographic study. ( Celic, V; Ilic, S; Tadic, M, 2014)
"Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some cardiac hypertrophy models."3.76Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. ( Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL, 2010)
"Recent data suggest that low triiodothyronine (T3) syndrome may contribute to the pathophysiology of cardiac diseases."3.75[Low T3 syndrome and left ventricular diastolic function]. ( Bianchi, M; Bindi, M; Cassetti, G; Castiglioni, M; Pinelli, M, 2009)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."3.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Hyperthyroidism was induced in rats by l-thyroxine administration (12 mg/L in drinking water, 4 weeks)."3.73Myocardial antioxidant enzyme activities and concentration and glutathione metabolism in experimental hyperthyroidism. ( Araujo, AS; Belló-Klein, A; Enzveiler, A; Fernandes, TR; Irigoyen, MC; Llesuy, S; Partata, WA; Ribeiro, MF; Schenkel, P, 2006)
"Amioradone-induced hyperthyroidism is a common complication of amiodarone therapy."3.72[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131]. ( Arlot, S; Hermida, JS; Jarry, G; Moullart, V; Rey, JL; Schvartz, C; Tcheng, E, 2004)
"Low-T3 syndrome is a strong predictor of death in cardiac patients and might be directly implicated in the poor prognosis of cardiac patients."2.71Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. ( Donato, L; Iervasi, G; L'Abbate, A; Landi, P; Pingitore, A; Raciti, M; Ripoli, A; Scarlattini, M, 2003)
"Hypothyroidism is often associated with adverse cardiovascular risk factors such as high cholesterol together with hypertension, endothelial dysfunction, and other atherosclerotic cardiovascular risk factors."2.44Treatment of hypothyroidism in elderly patients and in patients with cardiac disease. ( Feldt-Rasmussen, U, 2007)
"However, treatment of hypothyroidism and hyperthyroidism corrected cardiac irisin levels (Fig."1.48Both experimental hypothyroidism and hyperthyroidism increase cardiac irisin levels in rats. ( Atici, E; Baltaci, AK; Menevse, E; Mogulkoc, R, 2018)
"Patients with hypothyroidism are at a higher risk for coronary vascular disease."1.35Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function. ( Gerdes, AM; Liu, Y; Redetzke, RA; Sherer, BA; Wang, D, 2009)
"Lycopus extract was tested in thyroxine treated hyperthyroid rats (0."1.33Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats. ( Baumgartner, A; Biller, A; Hegger, M; Korte, B; Vonhoff, C; Winterhoff, H, 2006)
"Subclinical hyperthyroidism has been associated with harmful cardiac effects, but its treatment remains controversial."1.32The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. ( Garbeline, B; Romaldini, JH; Sgarbi, JA; Villaça, FG; Villar, HE, 2003)
"The results of a survey on the treatment of hypothyroidism by Dutch internists, working in different types of hospitals, are described."1.28Treatment of hypothyroidism in The Netherlands. Results of a survey of Dutch internists. ( Geelhoed-Duyvestijn, PH; Haak, A; Hermans, J; van der Heide, D, 1989)
"Hyperthyroidism was a more frequent (9."1.27Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. ( Aghini-Lombardi, F; Aronin, N; Fay, M; Haffajee, C; Lenziardi, M; Macchia, E; Martino, E; Pacchiarotti, A; Rajatanavin, R; Safran, M, 1984)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199034 (42.50)18.7374
1990's11 (13.75)18.2507
2000's19 (23.75)29.6817
2010's15 (18.75)24.3611
2020's1 (1.25)2.80

Authors

AuthorsStudies
Mastroianno, S1
Di Stolfo, G1
Maggio, A1
Pacilli, M1
Potenza, DR1
Massaro, R1
De Luca, G1
Russo, A1
Wang, Y1
Zhu, S1
Liu, H1
Wei, W1
Tu, Y1
Chen, C1
Song, J1
Li, J1
Sun, S1
Wang, C1
Xu, Z1
Saad, NS1
Repas, SJ1
Floyd, K1
Janssen, PML1
Elnakish, MT1
Atici, E1
Menevse, E1
Baltaci, AK1
Mogulkoc, R1
Dischinger, U1
Fassnacht, M1
Dietlein, M1
Drzezga, A1
Tadic, M1
Ilic, S1
Celic, V1
Andersen, MN1
Olsen, AS1
Madsen, JC1
Kristensen, SL1
Faber, J1
Torp-Pedersen, C1
Gislason, GH1
Selmer, C1
Liu, Y1
Wang, D1
Redetzke, RA1
Sherer, BA1
Gerdes, AM1
Bros, JA1
Lluís, PG1
Cabot, GL1
Pedragós, AC1
Cassetti, G1
Pinelli, M1
Bindi, M1
Bianchi, M1
Castiglioni, M1
Carneiro-Ramos, MS1
Diniz, GP1
Nadu, AP1
Almeida, J1
Vieira, RL1
Santos, RA1
Barreto-Chaves, ML1
Romano, MM1
Maciel, LM1
Almeida-Filho, OC1
Pazin-Filho, A1
Schmidt, A1
Maciel, BC1
Reverter, JL1
Colomé, E1
Puig Domingo, M1
Julián, T1
Halperin, I1
Sanmartí, A1
Mete, O1
Asa, SL1
Ozturk, S2
Dikbas, O2
Ozyasar, M2
Ayhan, S1
Ozlu, F2
Baltaci, D2
Erdem, A2
Alcelik, A2
Tosun, M2
Yazici, M2
Ayhan, SS1
Gurmach, MA1
Chizhov, PA1
Smirnova, MP1
Medvedeva, TM1
Walsh, JP1
Iervasi, G1
Pingitore, A1
Landi, P1
Raciti, M1
Ripoli, A1
Scarlattini, M1
L'Abbate, A1
Donato, L1
Sgarbi, JA1
Villaça, FG1
Garbeline, B1
Villar, HE1
Romaldini, JH1
STREBEL, R1
BAJUSZ, E1
SELYE, H1
RAAB, W1
KURTZMAN, RS1
OTTO, DL1
CHEPEY, JJ1
Hermida, JS1
Jarry, G1
Tcheng, E1
Moullart, V1
Arlot, S1
Rey, JL1
Schvartz, C1
Clarke, N1
Kabadi, UM1
Vonhoff, C1
Baumgartner, A1
Hegger, M1
Korte, B1
Biller, A1
Winterhoff, H1
Araujo, AS1
Ribeiro, MF1
Enzveiler, A1
Schenkel, P1
Fernandes, TR1
Partata, WA1
Irigoyen, MC1
Llesuy, S1
Belló-Klein, A1
Trivieri, MG1
Oudit, GY1
Sah, R1
Kerfant, BG1
Sun, H1
Gramolini, AO1
Pan, Y1
Wickenden, AD1
Croteau, W1
Morreale de Escobar, G1
Pekhletski, R1
St Germain, D1
Maclennan, DH1
Backx, PH1
Berti, P1
Materazzi, G1
Bogazzi, F1
Ambrosini, CE1
Martino, E2
Miccoli, P1
Israel, O1
Weiler-Sagie, M1
Rispler, S1
Bar-Shalom, R1
Frenkel, A1
Keidar, Z1
Bar-Shalev, A1
Strauss, HW1
Samuels, MA1
Feldt-Rasmussen, U1
Tran, HA1
Safran, M1
Aghini-Lombardi, F1
Rajatanavin, R1
Lenziardi, M1
Fay, M1
Pacchiarotti, A1
Aronin, N1
Macchia, E1
Haffajee, C1
Schneider, R1
Brandt, CM1
Fincker, JL1
Límanová, Z1
Simonová, J1
Felt, V2
Cenková, V2
Nedvídková, J2
Holzworth, J1
Theran, P1
Carpenter, JL1
Harpster, NK1
Todoroff, RJ1
Carnell, NE1
Wilber, JF1
Kraft, W1
Dietl, A1
Georgiou, S1
Christofidis, I1
Davies, PH1
Black, EG1
Sheppard, MC1
Franklyn, JA1
Mariotti, S1
Cabula, R1
Petrini, L1
Caradonna, A1
Mercuro, G1
Cherchi, A1
Shapiro, LE1
Sievert, R1
Ong, L1
Ocampo, EL1
Chance, RA1
Lee, M1
Nanna, M1
Ferrick, K1
Surks, MI1
Aoyagi, S1
Shimada, S1
Kosuga, K1
Ohishi, K1
Yeo, PP1
Loh, KC1
Stevenson, HP1
Archbold, GP1
Johnston, P1
Young, IS1
Sheridan, B1
del Cerro Marín, M1
Fernández Ruiz, A1
García-Guereta, L1
Benito Bartolomé, F1
Burgueros, M1
Ares Segura, S1
Moreno, F1
Gracia Bouthelier, R1
Fadel, BM1
Ellahham, S1
Ringel, MD1
Lindsay, J1
Wartofsky, L2
Burman, KD2
Klein, I2
Ojamaa, K1
Stathatos, N1
Levetan, C1
Wildenthal, K1
Starr, P1
Chopra, IJ1
Solomon, DH1
Hepner, GW1
Morgenstein, AA1
Gavin, LA1
Rosenthal, M1
Cavalieri, RR1
Schwartzkopff, W1
Russ, E1
Jayaratna, PS1
Sandric, S1
Di Gennaro, M1
Cocchi, A1
Trodella, L1
Ausili, GP1
Bellocci, F1
Carbonin, PU1
Spataro, A1
Rivlin, RS1
Badano, L1
Carratino, L1
Calisi, P1
Giunta, L1
Lucatti, A1
Sebe, T1
Kojima, A1
Aoki, H1
Kawai, H1
Saito, S1
Geelhoed-Duyvestijn, PH1
Haak, A1
Hermans, J1
van der Heide, D1
Csako, G1
Zweig, MH1
Benson, C1
Ruddel, M1
Lee, HY1
Suhl, J1
Pekary, AE1
Hershman, JM1
Földes, J2
Lengyel, Z2
Gesztesi, E2
Takács, I2
Hamburger, JI1
Paul, S1
Greene, R1
Gupta, MP1
Kim, S1
Kang, J1
Sherman, L1
Kolodny, HD1
Hamby, RI1
Levey, GS1
Epstein, SE1
Hedley, AJ1
Blum, M1
Shimoda, S1
Bencze, WL1
Hess, R1
DeStevens, G1
Postelnicu, D1
Frey, H1
Kattus, AA1
Biscoe, BW1
Dashe, AM1
Davis, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypothyroidism[NCT02467244]120 participants (Actual)Observational2017-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for thyroxine and Heart Diseases

ArticleYear
[Thyroid gland and the heart : Pathophysiological background, diagnostic and therapeutic consequences].
    Der Internist, 2018, Volume: 59, Issue:7

    Topics: Heart Diseases; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Thyrotropin; Thyroxin

2018
[Primary hypothyroidism: Considerations for a rational use of levothyroxine therapy].
    Medicina clinica, 2011, Feb-26, Volume: 136, Issue:5

    Topics: Adult; Atrial Fibrillation; Autoimmune Diseases; Comorbidity; Contraindications; Dose-Response Relat

2011
Dissatisfaction with thyroxine therapy - could the patients be right?
    Current opinion in pharmacology, 2002, Volume: 2, Issue:6

    Topics: Bone Diseases; Drug Therapy, Combination; Heart Diseases; Humans; Hypothyroidism; Patient Satisfacti

2002
NEUROGENIC MULTIFOCAL DESTRUCTION OF MYOCARDIAL TISSUE (PATHOGENIC MECHANISM AND ITS PREVENTION).
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Adrenal Cortex Hormones; Catecholamines; Epinephrine; Heart Diseases; Hypoxia; Myocardial Infarction

1963
Optimizing treatment of hypothyroidism.
    Treatments in endocrinology, 2004, Volume: 3, Issue:4

    Topics: Aged; Aging; Coronary Disease; Dose-Response Relationship, Drug; Estrogen Replacement Therapy; Femal

2004
The brain-heart connection.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Catecholamines; Cats; Culture; Death, Su

2007
Treatment of hypothyroidism in elderly patients and in patients with cardiac disease.
    Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:7

    Topics: Aged; Heart Diseases; Humans; Hypothyroidism; Safety; Thyroxine

2007
[The heart and hypothyroidism].
    Cardiologia (Rome, Italy), 1995, Volume: 40, Issue:12 Suppl 1

    Topics: Arteriosclerosis; Autoimmunity; Cardiovascular System; Echocardiography; Exercise Test; Heart Diseas

1995
Subclinical thyrotoxicosis.
    Advances in internal medicine, 1998, Volume: 43

    Topics: Atrial Fibrillation; Biomarkers; Bone and Bones; Bone Density; Bone Resorption; Diagnosis, Different

1998
Hyperthyroid heart disease.
    Clinical cardiology, 2000, Volume: 23, Issue:6

    Topics: Atrial Fibrillation; Heart; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Myocardial Contr

2000
Thyroid hormone and the cardiovascular system.
    The New England journal of medicine, 2001, Feb-15, Volume: 344, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart; Heart Diseases

2001
The controversy of the treatment of critically ill patients with thyroid hormone.
    Best practice & research. Clinical endocrinology & metabolism, 2001, Volume: 15, Issue:4

    Topics: Animals; Critical Care; Critical Illness; Heart Diseases; Humans; Infections; Respiration; Shock; Th

2001
Lysosomes and lysosomal enzymes in the heart.
    Frontiers of biology, 1975, Volume: 43, Issue:4

    Topics: Acid Phosphatase; Adrenal Cortex Hormones; Animals; Cardiomegaly; Cathepsins; Centrifugation, Densit

1975
Atherosclerosis, hypothyroidism, and thyroid hormone therapy.
    Advances in lipid research, 1978, Volume: 16

    Topics: Arteriosclerosis; Female; Genital Diseases, Female; Heart Diseases; Humans; Hypercholesterolemia; Hy

1978
Thyroid hormone and the cardiovascular system.
    The American journal of medicine, 1990, Volume: 88, Issue:6

    Topics: Heart; Heart Diseases; Hemodynamics; Humans; Myocardial Contraction; Thyroid Diseases; Thyroxine; Tr

1990
Myxoedema.
    The Practitioner, 1972, Volume: 208, Issue:245

    Topics: Anemia; Blood Coagulation Disorders; Central Nervous System Diseases; Electrocardiography; Female; G

1972
Myxedema coma.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:6

    Topics: Adrenal Glands; Cachexia; Central Nervous System; Coma; Heart Diseases; Humans; Hypoglycemia; Hypona

1972
[Treatment of myxedema].
    Saishin igaku. Modern medicine, 1970, Volume: 25, Issue:3

    Topics: Diuretics; Heart Diseases; Humans; Myxedema; Thyroid Diseases; Thyroid Hormones; Thyronines; Thyroxi

1970
Hypolipidemic agents.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1969, Volume: 13

    Topics: Acetates; Adult; Animals; Azoles; Butyrates; Cholesterol; Cholestyramine Resin; Coronary Disease; Di

1969

Trials

4 trials available for thyroxine and Heart Diseases

ArticleYear
Myocardial ultrasonic tissue characterization in patients with thyroid dysfunction.
    Cardiovascular ultrasound, 2010, Apr-23, Volume: 8

    Topics: Adult; Antithyroid Agents; Diagnosis, Differential; Echocardiography, Doppler; Female; Heart Disease

2010
Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease.
    Circulation, 2003, Feb-11, Volume: 107, Issue:5

    Topics: Aged; Female; Follow-Up Studies; Heart Diseases; Humans; Hyperlipidemias; Logistic Models; Male; Mid

2003
Minimal cardiac effects in asymptomatic athyreotic patients chronically treated with thyrotropin-suppressive doses of L-thyroxine.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:8

    Topics: Adult; Female; Heart Diseases; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Myocardial C

1997
[Comparative studies of the lipid-lowering activity of etiroxate hydrochloride and dextrothyroxine (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, May-09, Volume: 117, Issue:19

    Topics: Adult; Aged; Cholesterol; Clinical Trials as Topic; Female; Heart; Heart Diseases; Humans; Hyperlipi

1975

Other Studies

57 other studies available for thyroxine and Heart Diseases

ArticleYear
Role of Subclinical Iatrogenic Hyperthyroidism in the Setting of Heart Disease and Arrhythmic Burden.
    Endocrine, metabolic & immune disorders drug targets, 2020, Volume: 20, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Asymptomatic Diseases; Cardiovascular System; Female; Heart Diseases; Ho

2020
Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice.
    Disease markers, 2019, Volume: 2019

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Di

2019
Recovery following Thyroxine Treatment Withdrawal, but Not Propylthiouracil, Averts In Vivo and Ex Vivo Thyroxine-Provoked Cardiac Complications in Adult FVB/N Mice.
    BioMed research international, 2017, Volume: 2017

    Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Ventricles; Male; Mice; Myocardial Contraction

2017
Both experimental hypothyroidism and hyperthyroidism increase cardiac irisin levels in rats.
    Bratislavske lekarske listy, 2018, Volume: 119, Issue:1

    Topics: Animals; Disease Models, Animal; Fibronectins; Heart; Heart Diseases; Hyperthyroidism; Hypothyroidis

2018
    Nuklearmedizin. Nuclear medicine, 2018, Volume: 57, Issue:5

    Topics: Atherosclerosis; Cognition Disorders; Drug Utilization; Heart Diseases; Humans; Hypothyroidism; Rena

2018
Right ventricular and right atrial function and deformation in patients with subclinical hypothyroidism: a two- and three-dimensional echocardiographic study.
    European journal of endocrinology, 2014, Volume: 170, Issue:1

    Topics: Adult; Atrial Function, Right; Atrial Remodeling; Cardiac Volume; Echocardiography, Doppler, Pulsed;

2014
Long-Term Outcome in Levothyroxine Treated Patients With Subclinical Hypothyroidism and Concomitant Heart Disease.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Denmark; Female; Follow-Up Studies; Heart Diseases; Hos

2016
Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Angiogenesis Inducing Agents; Animals; Body Temperature; Coronary Vessels; Diiodothyronines; Disease

2009
[Low T3 syndrome and left ventricular diastolic function].
    Giornale italiano di cardiologia (2006), 2009, Volume: 10, Issue:8

    Topics: Aged; Biomarkers; Case-Control Studies; Diastole; Echocardiography, Doppler; Euthyroid Sick Syndrome

2009
Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.
    Basic research in cardiology, 2010, Volume: 105, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Disease Models, A

2010
[Clinical endocrinologists' perception of the deleterious effects of TSH suppressive therapy in patients with differentiated thyroid carcinoma].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2010, Volume: 57, Issue:8

    Topics: Adult; Attitude of Health Personnel; Carcinoma; Cognition Disorders; Cross-Sectional Studies; Data C

2010
Images in endocrine pathology: thyrotoxicosis associated with destructive thyroiditis.
    Endocrine pathology, 2012, Volume: 23, Issue:3

    Topics: Amiodarone; Heart Diseases; Humans; Male; Middle Aged; Thyroidectomy; Thyroiditis; Thyrotoxicosis; T

2012
Evaluation of left atrial mechanical functions and atrial conduction abnormalities in patients with clinical hypothyroid.
    Cardiology journal, 2012, Volume: 19, Issue:3

    Topics: Adult; Atrial Function, Left; Biomarkers; Biomechanical Phenomena; Case-Control Studies; Echocardiog

2012
Evaulation of atrial conduction abnormalities and left atrial mechanical functions in patients with subclinical thyroid disorders.
    Endokrynologia Polska, 2012, Volume: 63, Issue:4

    Topics: Adult; Atrial Function, Left; Biomarkers; Case-Control Studies; Female; Heart Atria; Heart Conductio

2012
[Immunological characteristics in subjects with heart connective tissue dysplasia depending on thyroid hormone levels and vegetative dysfunction].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:10

    Topics: Connective Tissue Diseases; Female; Heart Diseases; Humans; Immunoglobulin A; Immunoglobulin G; Immu

2012
The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:4

    Topics: Adolescent; Adult; Aged; Antithyroid Agents; Arrhythmias, Cardiac; Diastole; Echocardiography; Elect

2003
Fasting as a protective stressor against the potential cardiotoxic action of various agents.
    Cardiologia, 1962, Volume: 41

    Topics: Action Potentials; Antimalarials; Dihydrotachysterol; Fasting; Heart Diseases; Stress, Physiological

1962
MYXEDEMA HEART DISEASE.
    Radiology, 1965, Volume: 84

    Topics: Angiocardiography; Drug Therapy; Exudates and Transudates; Geriatrics; Heart Diseases; Heart Functio

1965
[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131].
    Archives des maladies du coeur et des vaisseaux, 2004, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Hea

2004
Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats.
    Life sciences, 2006, Feb-02, Volume: 78, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Body Temperature; Body Weight; Eatin

2006
Myocardial antioxidant enzyme activities and concentration and glutathione metabolism in experimental hyperthyroidism.
    Molecular and cellular endocrinology, 2006, Apr-25, Volume: 249, Issue:1-2

    Topics: Animals; Antioxidants; Catalase; Glutathione; Glutathione Transferase; Heart Diseases; Hyperthyroidi

2006
Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Apr-11, Volume: 103, Issue:15

    Topics: Animals; Blood Pressure; Calcium Signaling; Calcium-Transporting ATPases; Gene Expression Regulation

2006
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study.
    Langenbeck's archives of surgery, 2007, Volume: 392, Issue:6

    Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B

2007
PET/CT quantitation of the effect of patient-related factors on cardiac 18F-FDG uptake.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Benzodiazepines; Bezafibrate; Diabetes Mellitus; Drug Interac

2007
Gland handling.
    The American journal of medicine, 2007, Volume: 120, Issue:11

    Topics: Autoimmune Diseases; Female; Heart Diseases; Humans; Hypothyroidism; Middle Aged; Thyroxine

2007
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hypot

1984
[Diagnosis of toxic adenoma in a cardiology service: limits of thyroid hormone levels].
    Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 1983, Volume: 120, Issue:1

    Topics: Aged; Female; Heart Diseases; Humans; Hyperthyroidism; Male; Retrospective Studies; Thyroid Hormones

1983
[Determination of the levels of thyroxine, triiodothyronine and reverse triiodothyronine in heart disease].
    Vnitrni lekarstvi, 1983, Volume: 29, Issue:10

    Topics: Female; Heart Diseases; Humans; Male; Middle Aged; Thyroxine; Triiodothyronine; Triiodothyronine, Re

1983
Changes of triiodothyronine and thyroxine in patients with thyrocardiac disease and their relationship to systolic time intervals.
    Endokrinologie, 1982, Volume: 80, Issue:3

    Topics: Achilles Tendon; Adult; Aged; Coronary Disease; Female; Heart Diseases; Humans; Hyperthyroidism; Mal

1982
Hyperthyroidism in the cat: ten cases.
    Journal of the American Veterinary Medical Association, 1980, Feb-15, Volume: 176, Issue:4

    Topics: Animals; Cat Diseases; Cats; Female; Heart Diseases; Hyperthyroidism; Hypocalcemia; Male; Postoperat

1980
[Disturbed thyroxine and triiodothyronine metabolism in patients with heart involvement in thyrotoxicosis].
    Vnitrni lekarstvi, 1980, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Aged; Female; Heart Diseases; Humans; Hyperthyroidism; Male; Middle Aged; Thyroxi

1980
Primary hypothyroidism.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Costs and Cost Analysis; Heart Diseases; Humans; Hypothyroidism; Thyroxine

1994
[Total thyroxine (T4) and free thyroxine (FT4) in hypothyroidism and nonthyroid diseases of dogs].
    Tierarztliche Praxis, 1994, Volume: 22, Issue:5

    Topics: Alopecia; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; Dogs;

1994
Radioimmunoassay of free thyroxine (T4) using 125I-labeled T4-IgG complex with very large molecular weight.
    Clinica chimica acta; international journal of clinical chemistry, 1996, Jan-31, Volume: 244, Issue:2

    Topics: Female; Heart Diseases; Humans; Hyperthyroidism; Hypothyroidism; Immunoglobulin G; Iodine Radioisoto

1996
Relation between serum interleukin-6 and thyroid hormone concentrations in 270 hospital in-patients with non-thyroidal illness.
    Clinical endocrinology, 1996, Volume: 44, Issue:2

    Topics: Euthyroid Sick Syndromes; Heart Diseases; Humans; Interleukin-6; Kidney Diseases; Liver Diseases; Th

1996
[Thyroid-pituitary response to cardiopulmonary bypass].
    Rinsho kyobu geka = Japanese annals of thoracic surgery, 1988, Volume: 8, Issue:5

    Topics: Adult; Cardiopulmonary Bypass; Female; Heart Diseases; Humans; Male; Middle Aged; Thyrotropin; Thyro

1988
Misleading serum free thyroxine results during low molecular weight heparin treatment.
    Clinical chemistry, 1998, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Artifacts; Blood Proteins; Enoxaparin; Fatty Acids,

1998
[Thyroid function alterations in children with congenital cardiac disease after catheterization with iodinated contrast agents].
    Revista espanola de cardiologia, 2000, Volume: 53, Issue:4

    Topics: Cardiac Catheterization; Child, Preschool; Contrast Media; Female; Heart Diseases; Humans; Hypothyro

2000
Misleadingly low free thyroxine index and usefulness of reverse triiodothyronine measurement in nonthyroidal illnesses.
    Annals of internal medicine, 1979, Volume: 90, Issue:6

    Topics: Adult; Aged; Diagnosis, Differential; Diagnostic Errors; Evaluation Studies as Topic; Heart Diseases

1979
The diagnostic dilemma of isolated hyperthyroxinemia in acute illness.
    JAMA, 1979, Jul-20, Volume: 242, Issue:3

    Topics: Acute Disease; Aged; Asthma; Carcinoma, Bronchogenic; Female; Heart Diseases; Humans; Infections; Li

1979
Hypothyroidism with episodic psychiatric and cardiac manifestations.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:8

    Topics: Cognition Disorders; Confusion; Electrocardiography; Electroencephalography; Female; Heart Diseases;

1976
[Echocardiographic study of myxedematous heart disease].
    Bollettino della Societa italiana di cardiologia, 1976, Volume: 21, Issue:8

    Topics: Adult; Echocardiography; Female; Heart; Heart Diseases; Humans; Hypothyroidism; Male; Middle Aged; M

1976
Therapy of obesity with hormones.
    The New England journal of medicine, 1975, Jan-02, Volume: 292, Issue:1

    Topics: Adult; Animals; Child; Chorionic Gonadotropin; Growth Hormone; Heart Diseases; Humans; Injections, I

1975
Concentric left ventricular wall thickening in a patient with primary hypothyroidism. Response to gradual thyroxine replacement.
    Giornale italiano di cardiologia, 1991, Volume: 21, Issue:5

    Topics: Adult; Heart Diseases; Heart Ventricles; Humans; Hypothyroidism; Male; Thyroxine

1991
[A case of myxedema heart showing the improvement of impaired alpha-hANP secretion by administration of ATP and dibutyryl cAMP].
    Kokyu to junkan. Respiration & circulation, 1990, Volume: 38, Issue:10

    Topics: Adenosine Triphosphate; Adult; Atrial Natriuretic Factor; Bucladesine; Chronic Disease; Drug Therapy

1990
Treatment of hypothyroidism in The Netherlands. Results of a survey of Dutch internists.
    The Netherlands journal of medicine, 1989, Volume: 34, Issue:1-2

    Topics: Age Factors; Heart Diseases; Hospitals, General; Hospitals, Teaching; Humans; Hypothyroidism; Intern

1989
On the albumin-dependence of measurements of free thyroxin. II. Patients with non-thyroidal illness.
    Clinical chemistry, 1987, Volume: 33, Issue:1

    Topics: Diagnostic Errors; Dialysis; Heart Diseases; Humans; Neoplasms; Radioimmunoassay; Serum Albumin; Sta

1987
Secretion of thyrotropin with reduced concanavalin-A-binding activity in patients with severe nonthyroid illness.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 65, Issue:5

    Topics: Adult; Aged; Concanavalin A; Heart Diseases; Humans; Lung Diseases; Middle Aged; Protein Binding; Ra

1987
[The significance of the determination of the "free thyroxine" index in internal diseases].
    Orvosi hetilap, 1967, Volume: 108, Issue:37

    Topics: Heart Diseases; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroxine

1967
[The determination of the "free thyroxine" index in internal diseases].
    Nuclear-Medizin, 1967, Jul-15, Volume: 6, Issue:2

    Topics: Diagnosis, Differential; Erythrocytes; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Hypot

1967
When and how to use higher 131-I doses for hyperthyroidism.
    The New England journal of medicine, 1968, Dec-19, Volume: 279, Issue:25

    Topics: Adult; Age Factors; Aged; Antithyroid Agents; Female; Follow-Up Studies; Graves Disease; Heart Disea

1968
Hypothyroidism and heart-disease.
    Lancet (London, England), 1970, Apr-04, Volume: 1, Issue:7649

    Topics: Angina Pectoris; Heart Diseases; Humans; Hypothyroidism; Propranolol; Thyroxine

1970
Isolated TSH deficiency presenting as myxedema heart disease.
    JAMA, 1971, Jul-12, Volume: 217, Issue:2

    Topics: Adult; Angiography; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Diagnosis, Differential;

1971
Myocardial adenyl cyclase: activation by thyroid hormones and evidence for two adenyl cyclase systems.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:9

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cats; Cyclic AMP; Enzymes;

1969
[Action of an antioxidant substance (alpha-tocopherol) on the myocardium of rats treated with thyroxine].
    Studii si cercetari de endocrinologie, 1972, Volume: 23, Issue:3

    Topics: Animals; Heart; Heart Diseases; Hyperthyroidism; Myocardium; Rats; Thyroxine; Vitamin E

1972
[The heart during hyper- and hypothyroidism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1969, Aug-15, Volume: 89, Issue:16

    Topics: Animals; Dogs; Heart Diseases; Humans; Thyroid Diseases; Thyroxine

1969
Spurious heart disease induced by digitalis-containing reducing pills.
    Archives of internal medicine, 1968, Volume: 122, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Cathartics; Coronary Disease; Dextroamphetamine; Digitalis Glycosides;

1968