thyroxine has been researched along with Head and Neck Neoplasms in 27 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thyroid function was measured by means of thyroid stimulating hormone (TSH), free thyroxine (FT4) and free triiodthyronine (FT3) in 43 patients who had nonthyroid head-neck carcinomas treated by radiotherapy or radiotherapy in combination with other modalities." | 3.80 | Hypothyroidism after radiotherapy of head and neck cancer. ( Bernát, L; Hrušák, D, 2014) |
| "Primary hypothyroidism is one of the late complications that can occur after radiation therapy for malignant tumors in the head and neck region." | 1.56 | Model-based calculation of thyroid gland normal tissue complication probability in head and neck cancer patients after radiation therapy. ( Balentová, S; Ďuroška, M; Hajtmanová, E; Kinclová, I; Kozlíková, K; Matula, P; Muríň, P, 2020) |
| "Hypothyroidism is an established adverse effect of radiation therapy for head and neck cancer, and computed tomography (CT) density of the thyroid gland is lower in hypothyroid than euthyroid individuals." | 1.48 | Computed Tomography Density Change in the Thyroid Gland Before and After Radiation Therapy. ( Aizawa, T; Ishibashi, N; Maebayashi, T; Matsushita, J; Okada, M; Sakaguchi, M, 2018) |
| "Hypothyroidism is a late side effect after curative radiotherapy in the head and neck region." | 1.42 | Thyroid dysfunction after intra-arterial chemotherapy for hypopharyngeal and laryngeal cancer. ( Endo, K; Kondo, S; Masatani, T; Murono, S; Tsuji, A; Wakisaka, N; Yoshizaki, T, 2015) |
| "A total of 114 patients with head and neck cancer whose radiotherapy fields included the thyroid gland were analysed." | 1.40 | Dose-volumetric parameters for predicting hypothyroidism after radiotherapy for head and neck cancer. ( Kim, MY; Wu, HG; Yu, T, 2014) |
| "To determine the dose-response relationship of the thyroid for radiation-induced hypothyroidism in head-and-neck radiation therapy, according to 6 normal tissue complication probability models, and to find the best-fit parameters of the models." | 1.39 | Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy. ( Bakhshandeh, M; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A; Vasheghani, M, 2013) |
| "Radiation-induced thyroiditis is regarded as primary damage to the thyroid gland." | 1.38 | Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography. ( Bakhshandeh, M; Edraki, HR; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A, 2012) |
| "Hypothyroidism was defined as elevated serum TSH with decreased or normal free thyroxin (T4)." | 1.38 | A prospective cohort study on radiation-induced hypothyroidism: development of an NTCP model. ( Beetz, I; Bijl, HP; Boomsma, MJ; Chouvalova, O; Christianen, ME; Langendijk, JA; Oosting, SF; Schilstra, C; Steenbakkers, RJ; van der Laan, BF; Wolffenbuttel, BH, 2012) |
| "Hypothyroidism is recognized as a common complication of treatment in patients with head and neck carcinoma (HNC) and is reported in up to 75% of patients who receive combined treatment." | 1.31 | Pretreatment prevalence of hypothyroidism in patients with head and neck carcinoma. ( Bedrin, L; Dori, S; Horowitz, Z; Kronenberg, J; Mini, S; Peleg, M; Shoshani, Y; Taicher, S; Talmi, YP; Wolf, M, 2001) |
| "Another 16% had mild primary hypothyroidism (TSH, 5-15 mU/L)." | 1.30 | Diagnosis of hidden central hypothyroidism in survivors of childhood cancer. ( Broome, DC; Burghen, GA; Heideman, RL; Hudson, MM; Kun, LE; Li, H; Lustig, RH; Pitukcheewanont, P; Rose, SR, 1999) |
| "Hypothyroidism is not commonly considered a complication of radiotherapy for head and neck cancer." | 1.28 | Hypothyroidism following radiotherapy for head and neck cancer. ( Blakeslee, DB; Duncan, NO; Liening, DA; Smith, DB, 1990) |
| "The mean thyroid dose for irradiated malignant lymphomas in the prospective and the retrospective group was 45 Gy and 43 Gy respectively." | 1.28 | Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis. ( Becker, W; Feyerabend, T; Kapp, B; Reiners, C; Richter, E, 1990) |
| "Eleven patients with head and neck cancer (ten men, one woman; mean age, 65 years) (larynx, six; oropharynx, two; tongue, one; skin, one; thyroid, one) with regional lymph node enlargements either in contiguity or firmly adherent to the vascular structures of the neck have been treated by means of external microwaves (915, 434 MHz) applicators." | 1.28 | Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis. ( Airoldi, M; Brossa, PC; D'Alberto, M; Gabriele, P; Pedani, F; Ragona, R; Tseroni, V, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Gülses, A | 1 |
| Wagner, J | 1 |
| Torst, P | 1 |
| Wieker, H | 1 |
| Schulte, DM | 1 |
| Spille, DC | 1 |
| Wiltfang, J | 1 |
| Spille, J | 1 |
| Kinclová, I | 1 |
| Hajtmanová, E | 1 |
| Matula, P | 1 |
| Balentová, S | 1 |
| Muríň, P | 1 |
| Ďuroška, M | 1 |
| Kozlíková, K | 1 |
| Zhu, L | 1 |
| Zhu, X | 1 |
| Zhou, B | 1 |
| Mao, WB | 1 |
| Wu, Y | 1 |
| Cheng, F | 1 |
| Ishibashi, N | 1 |
| Maebayashi, T | 1 |
| Aizawa, T | 1 |
| Sakaguchi, M | 1 |
| Okada, M | 1 |
| Matsushita, J | 1 |
| Bernát, L | 1 |
| Hrušák, D | 1 |
| Kim, MY | 1 |
| Yu, T | 1 |
| Wu, HG | 1 |
| Endo, K | 1 |
| Masatani, T | 1 |
| Tsuji, A | 1 |
| Kondo, S | 1 |
| Wakisaka, N | 1 |
| Murono, S | 1 |
| Yoshizaki, T | 1 |
| Bölling, T | 1 |
| Geisenheiser, A | 1 |
| Pape, H | 1 |
| Martini, C | 1 |
| Rübe, C | 1 |
| Timmermann, B | 1 |
| Fischedick, K | 1 |
| Kortmann, RD | 1 |
| Gerss, J | 1 |
| Koch, R | 1 |
| Willich, N | 1 |
| Bakhshandeh, M | 2 |
| Hashemi, B | 2 |
| Mahdavi, SR | 2 |
| Nikoofar, A | 2 |
| Edraki, HR | 1 |
| Kazemnejad, A | 2 |
| Vasheghani, M | 1 |
| Boomsma, MJ | 1 |
| Bijl, HP | 1 |
| Christianen, ME | 1 |
| Beetz, I | 1 |
| Chouvalova, O | 1 |
| Steenbakkers, RJ | 1 |
| van der Laan, BF | 1 |
| Wolffenbuttel, BH | 1 |
| Oosting, SF | 1 |
| Schilstra, C | 1 |
| Langendijk, JA | 1 |
| Kasner, DL | 1 |
| Spieth, ME | 1 |
| Starkman, ME | 1 |
| Zdor-North, D | 1 |
| Iguma, Y | 1 |
| Iwai, C | 1 |
| Okuyama, M | 1 |
| Futami, T | 1 |
| Asato, R | 1 |
| Inui, K | 1 |
| Koc, M | 1 |
| Unuvar, N | 1 |
| Sen, RC | 1 |
| Capoglu, I | 1 |
| Sen, M | 1 |
| Alterio, D | 1 |
| Jereczek-Fossa, BA | 1 |
| Franchi, B | 1 |
| D'Onofrio, A | 1 |
| Piazzi, V | 1 |
| Rondi, E | 1 |
| Ciocca, M | 1 |
| Gibelli, B | 1 |
| Grosso, E | 1 |
| Tradati, N | 1 |
| Mariani, L | 1 |
| Boboc, GI | 1 |
| Orecchia, R | 1 |
| Holten, I | 1 |
| Schimpff, SC | 1 |
| Diggs, CH | 1 |
| Wiswell, JG | 1 |
| Salvatore, PC | 1 |
| Wiernik, PH | 1 |
| Turner, SL | 1 |
| Tiver, KW | 1 |
| Boyages, SC | 1 |
| Shafford, EA | 1 |
| Kingston, JE | 1 |
| Healy, JC | 1 |
| Webb, JA | 1 |
| Plowman, PN | 1 |
| Reznek, RH | 1 |
| Rose, SR | 1 |
| Lustig, RH | 1 |
| Pitukcheewanont, P | 1 |
| Broome, DC | 1 |
| Burghen, GA | 1 |
| Li, H | 1 |
| Hudson, MM | 1 |
| Kun, LE | 1 |
| Heideman, RL | 1 |
| Mini, S | 1 |
| Dori, S | 1 |
| Horowitz, Z | 1 |
| Bedrin, L | 1 |
| Peleg, M | 1 |
| Wolf, M | 1 |
| Shoshani, Y | 1 |
| Taicher, S | 1 |
| Kronenberg, J | 1 |
| Talmi, YP | 1 |
| Olsholt, R | 1 |
| Stangeland, N | 1 |
| Liening, DA | 1 |
| Duncan, NO | 1 |
| Blakeslee, DB | 1 |
| Smith, DB | 1 |
| Feyerabend, T | 1 |
| Kapp, B | 1 |
| Richter, E | 1 |
| Becker, W | 1 |
| Reiners, C | 1 |
| Airoldi, M | 1 |
| Gabriele, P | 1 |
| Brossa, PC | 1 |
| Pedani, F | 1 |
| Tseroni, V | 1 |
| D'Alberto, M | 1 |
| Ragona, R | 1 |
| Glatstein, E | 1 |
| McHardy-Young, S | 1 |
| Brast, N | 1 |
| Eltringham, JR | 1 |
| Kriss, JP | 1 |
| Hales, I | 1 |
| Reeve, T | 1 |
| Johnson, D | 1 |
27 other studies available for thyroxine and Head and Neck Neoplasms
| Article | Year |
|---|---|
Changes in hormones of the thyroid axis after tracheostomy and their influence on regeneration in patients with head and neck cancer: A prospective study.
Topics: Aged; Head and Neck Neoplasms; Humans; Prospective Studies; Regeneration; Thyroid Gland; Thyrotropin | 2022 |
Model-based calculation of thyroid gland normal tissue complication probability in head and neck cancer patients after radiation therapy.
Topics: Adult; Aged; Algorithms; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Dose-Response Rela | 2020 |
Multiple simple cystic metastases in the lateral neck at presentation with papillary thyroid microcarcinoma: A case report.
Topics: Carcinoma, Papillary; Head and Neck Neoplasms; Hormone Replacement Therapy; Humans; Lymphangioma; Ly | 2021 |
Computed Tomography Density Change in the Thyroid Gland Before and After Radiation Therapy.
Topics: Adult; Aged; Aged, 80 and over; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middl | 2018 |
Hypothyroidism after radiotherapy of head and neck cancer.
Topics: Aged; Carcinoma; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Follow-Up Studies; | 2014 |
Dose-volumetric parameters for predicting hypothyroidism after radiotherapy for head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Head and Neck Neoplasms; Huma | 2014 |
Thyroid dysfunction after intra-arterial chemotherapy for hypopharyngeal and laryngeal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Case-Control Studies; Chem | 2015 |
Hypothyroidism after head-and-neck radiotherapy in children and adolescents: preliminary results of the "Registry for the Evaluation of Side Effects After Radiotherapy in Childhood and Adolescence" (RiSK).
Topics: Adolescent; Child; Child, Preschool; Cranial Irradiation; Germany; Head and Neck Neoplasms; Hormone | 2011 |
Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography.
Topics: Adult; Aged; Aged, 80 and over; Arteries; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged | 2012 |
Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Confidence Intervals; Dose-Response Relationship, Radiation; Female; | 2013 |
A prospective cohort study on radiation-induced hypothyroidism: development of an NTCP model.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Area Under Curve; Chemoradiotherapy; Cohort Studies; | 2012 |
Thyroid carcinoma: iodine-131-negative whole-body scan reverses to positive after a combination of thyrogen stimulation and withdrawal.
Topics: Adenocarcinoma, Follicular; Carcinoma, Papillary; False Negative Reactions; Female; Head and Neck Ne | 2002 |
[Clinical usefulness of serum total cholesterol as an index of hypothyroidism in patients after cervical radiation].
Topics: Aged; Biomarkers; Cholesterol; Female; Head and Neck Neoplasms; Humans; Hypercholesterolemia; Hypoth | 2003 |
A prospective evaluation of early thyroid dysfunction on completion of neck radiotherapy.
Topics: Adult; Aged; Case-Control Studies; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neck | 2003 |
Thyroid disorders in patients treated with radiotherapy for head-and-neck cancer: a retrospective analysis of seventy-three patients.
Topics: Adult; Aged; Biomarkers; Dose-Response Relationship, Radiation; Female; Head and Neck Neoplasms; Hum | 2007 |
Acute response of the thyroid to external radiation.
Topics: Adult; Aged; Animals; Autoantibodies; Biopsy, Needle; Cell Nucleus; Cytoplasm; Female; Follow-Up Stu | 1983 |
Radiation-related thyroid dysfunction: implications for the treatment of Hodgkin's disease.
Topics: Adolescent; Adult; Child; Drug-Related Side Effects and Adverse Reactions; Follow-Up Studies; Head a | 1980 |
Thyroid dysfunction following radiotherapy for head and neck cancer.
Topics: Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middle Aged; Radia | 1995 |
Thyroid nodular disease after radiotherapy to the neck for childhood Hodgkin's disease.
Topics: Adolescent; Biopsy, Needle; Child; Child, Preschool; Dose-Response Relationship, Radiation; Female; | 1999 |
Diagnosis of hidden central hypothyroidism in survivors of childhood cancer.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Head and Neck Neoplasms; Humans; Hypot | 1999 |
Pretreatment prevalence of hypothyroidism in patients with head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; H | 2001 |
[Ectopic thyroid gland].
Topics: Child; Diagnosis, Differential; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radionuclide Ima | 1977 |
Hypothyroidism following radiotherapy for head and neck cancer.
Topics: Edema; Female; Head; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middle Aged; Neck; Radio | 1990 |
Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis.
Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyr | 1990 |
Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis.
Topics: Aged; Aged, 80 and over; Carcinoma; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Human | 1990 |
Alterations in serum thyrotropin (TSH) and thyroid function following radiotherapy in patients with malignant lymphoma.
Topics: Adolescent; Adult; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Hypothyroidism; Ion Exc | 1971 |
Managment of functioning thyroid cancer.
Topics: Adenocarcinoma; Adult; Aged; Biopsy; Digestive System; Female; Head and Neck Neoplasms; Hospitalizat | 1969 |