Page last updated: 2024-11-06

thyroxine and Harelip

thyroxine has been researched along with Harelip in 6 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"Pregnant A/WySn mice, 20 to 30% of whose offspring have spontaneous cleft lip, were treated with thyroxine."7.67Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain. ( Harris, MJ; Juriloff, DM, 1985)
"Pregnant A/WySn mice, 20 to 30% of whose offspring have spontaneous cleft lip, were treated with thyroxine."3.67Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain. ( Harris, MJ; Juriloff, DM, 1985)
" A study of the value of different thyroid hormones in the diagnosis of secondary and tertiary hypothyroidism showed that in spite of low free thyroxin concentrations the thyroxine and triiodothyronine levels are often normal."3.66Growth hormone deficiency: analysis of 49 patients. ( Bános, C; Gács, G; Kiss, S; Paraicz, E, 1981)
"RAX knockout mice have anophthalmia, cleft palate, and an abnormal hypothalamus and display perinatal lethality."1.51Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. ( Balikova, I; Boros, E; Brachet, C; Heinrichs, C; Kozhemyakina, EA; Mathers, PH; Smits, G; Soblet, J; Vilain, C, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brachet, C1
Kozhemyakina, EA1
Boros, E1
Heinrichs, C1
Balikova, I1
Soblet, J1
Smits, G1
Vilain, C1
Mathers, PH1
WOOLLAM, DH1
MILLEN, JW1
Gács, G1
Kiss, S1
Paraicz, E1
Bános, C1
Kremenová, J1
Bednár, J1
Soutorová, M1
Tolarová, M1
Reisenauer, R1
Juriloff, DM2
Harris, MJ1

Other Studies

6 other studies available for thyroxine and Harelip

ArticleYear
Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men.
    The Journal of clinical endocrinology and metabolism, 2019, 07-01, Volume: 104, Issue:7

    Topics: Animals; Anophthalmos; Antidiuretic Agents; Cleft Lip; Cleft Palate; Deamino Arginine Vasopressin; D

2019
Influence of thyroxine on the incidence of harelip in the "Strong A" line of mice.
    British medical journal, 1960, Apr-23, Volume: 1, Issue:5181

    Topics: Animals; Cleft Lip; Cleft Palate; Incidence; Mice; Thyroxine

1960
Growth hormone deficiency: analysis of 49 patients.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1981, Volume: 22, Issue:1-2

    Topics: Adolescent; Birth Weight; Child; Child, Preschool; Cleft Lip; Cleft Palate; Delivery, Obstetric; Fem

1981
Iodine metabolism in mothers of children with cleft lip and/or palate anomaly and in persons with endemic goitre.
    Endokrinologie, 1981, Volume: 78, Issue:2-3

    Topics: Adult; Cholesterol; Cleft Lip; Cleft Palate; Female; Goiter, Endemic; Humans; Hyperthyroidism; Iodin

1981
Thyroxin-induced differential mortality of mouse embryos with cleft lip.
    Developmental pharmacology and therapeutics, 1981, Volume: 2, Issue:1

    Topics: Animals; Cleft Lip; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Male; Mi

1981
Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain.
    Teratology, 1985, Volume: 31, Issue:3

    Topics: Animals; Cleft Lip; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Mice; Mi

1985