thyroxine has been researched along with HIV Coinfection in 34 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two patients who had taken levothyroxine at the same dose for several years and who had stable thyroid stimulating hormone (TSH) levels, and who developed clinical and biological hyperthyroidism following switch from ritonavir-boosted protease inhibitors (PIs) to dolutegravir-based HAART." | 7.85 | Early neuropsychological adverse events after switching from PI/r to dolutegravir could be related to hyperthyroidism in patients under levothyroxine. ( Bani-Sadr, F; Berger, JL; Hentzien, M; Lebrun, D; Marty, H; Migault, C; Nguyen, Y, 2017) |
| " Several cases of Cushing's syndrome have been reported when patients received inhaled therapy with fluticasone for asthma, sometimes complicated by secondary adrenal failure after stopping fluticasone." | 7.75 | [Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone]. ( Beressi, J-; Collet-Gaudillat, C; Desforges-Bullet, V; Doll, J; Petit-Aubert, G; Roussin-Bretagne, S, 2009) |
| "A 37-year-old woman with human immunodeficiency virus infection who had recently undergone thyroidectomy for a benign multinodular goiter presented to a clinic with hypothyroidism (she was also found to be pregnant), and treatment with levothyroxine 75 μg daily was initiated." | 4.95 | Probable interaction between levothyroxine and ritonavir: Case report and literature review. ( Ahmed, RA; Foisy, MM; Hughes, CA; Sahajpal, R, 2017) |
| "We report two patients who had taken levothyroxine at the same dose for several years and who had stable thyroid stimulating hormone (TSH) levels, and who developed clinical and biological hyperthyroidism following switch from ritonavir-boosted protease inhibitors (PIs) to dolutegravir-based HAART." | 3.85 | Early neuropsychological adverse events after switching from PI/r to dolutegravir could be related to hyperthyroidism in patients under levothyroxine. ( Bani-Sadr, F; Berger, JL; Hentzien, M; Lebrun, D; Marty, H; Migault, C; Nguyen, Y, 2017) |
| " Clinical data, serum thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels were retrospectively assessed in 137 children receiving anti-tuberculosis treatment including ETH." | 3.77 | Abnormal thyroid function tests in children on ethionamide treatment. ( Hesseling, AC; Magdorf, K; Schaaf, HS; Thee, S; Willemse, M; Zöllner, EW, 2011) |
| " Several cases of Cushing's syndrome have been reported when patients received inhaled therapy with fluticasone for asthma, sometimes complicated by secondary adrenal failure after stopping fluticasone." | 3.75 | [Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone]. ( Beressi, J-; Collet-Gaudillat, C; Desforges-Bullet, V; Doll, J; Petit-Aubert, G; Roussin-Bretagne, S, 2009) |
| " We describe a case of an HIV-infected patient, taking levothyroxine for hypothyroidism and clinically stable, who, after the introduction of an antiretroviral regimen containing indinavir, developed a pharmacological hyperthyroidism." | 3.71 | Interaction between levothyroxine and indinavir in a patient with HIV infection. ( Carolo, G; Concia, E; Faggian, F; Gatti, F; Lanzafame, M; Marcati, P; Trevenzoli, M, 2002) |
| "To assess thyroid function in symptomatic HIV-infected infants and children with failure to thrive and to evaluate clinical response in patients with hyperthyrotropinemia to levothyroxine." | 3.69 | Thyroid dysfunction in HIV-infected children: is L-thyroxine therapy beneficial? ( Iqbal, M; Nunlee-Bland, G; Rana, S; Valyasevi, R, 1996) |
| " Inappropriate maintenance of circulating 3,3',5-triiodothyronine (T3) levels could contribute to weight loss." | 3.68 | Indices of thyroid function and weight loss in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. ( Cavalieri, RR; Doerrler, W; Feingold, KR; Grunfeld, C; Jensen, P; Pang, M; Shimizu, L, 1993) |
| "Under sick euthyroid syndrome, we got only low FT3 as the biochemical abnormality." | 1.91 | Thyroid Function in Newly Diagnosed HIV-positive Patients. ( Dutta, SK; Kalita, BC, 2023) |
| "However, the development of Graves' disease (GD) in this clinical setting has not been reported to date." | 1.32 | Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection. ( Davey, RT; Falloon, J; Jimenez, C; Moran, SA; Sarlis, NJ; Sereti, I; Wynne, S; Yen, PM, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 15 (44.12) | 29.6817 |
| 2010's | 11 (32.35) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Dutta, SK | 1 |
| Kalita, BC | 1 |
| Sahajpal, R | 1 |
| Ahmed, RA | 1 |
| Hughes, CA | 1 |
| Foisy, MM | 1 |
| Ukibe, NR | 1 |
| Ukibe, SN | 1 |
| Emelumadu, OF | 1 |
| Onyenekwe, CC | 1 |
| Ahaneku, JE | 1 |
| Igwegbe, AO | 1 |
| Monago, IN | 1 |
| Ilika, AL | 1 |
| Rateni, L | 1 |
| Lupo, S | 1 |
| Racca, L | 1 |
| Palazzi, J | 1 |
| Ghersevich, S | 1 |
| Thaimuta, ZL | 1 |
| Sekadde-Kigondu, C | 1 |
| Makawiti, DW | 1 |
| Dev, N | 1 |
| Sahoo, R | 1 |
| Kulshreshtha, B | 1 |
| Gadpayle, AK | 1 |
| Sharma, SC | 1 |
| Hatzl, M | 1 |
| Öllinger, A | 1 |
| Geit, M | 1 |
| Wiesinger, K | 1 |
| Angerbauer, K | 1 |
| Auböck, J | 1 |
| Gabriel, M | 1 |
| Báez, MS | 1 |
| Zapata Silva, A | 1 |
| López Benavides, MI | 1 |
| Wilson, G | 1 |
| Ige, OM | 1 |
| Akinlade, KS | 1 |
| Rahamon, SK | 1 |
| Edem, VF | 1 |
| Arinola, OG | 1 |
| Berger, JL | 1 |
| Nguyen, Y | 1 |
| Lebrun, D | 1 |
| Migault, C | 1 |
| Hentzien, M | 1 |
| Marty, H | 1 |
| Bani-Sadr, F | 1 |
| Montes, ML | 1 |
| Fraile, JM | 1 |
| González, JJ | 1 |
| Arribas, JR | 1 |
| Collet-Gaudillat, C | 1 |
| Roussin-Bretagne, S | 1 |
| Desforges-Bullet, V | 1 |
| Petit-Aubert, G | 1 |
| Doll, J | 1 |
| Beressi, J- | 1 |
| Jain, G | 1 |
| Devpura, G | 1 |
| Gupta, BS | 1 |
| Thee, S | 1 |
| Zöllner, EW | 1 |
| Willemse, M | 1 |
| Hesseling, AC | 1 |
| Magdorf, K | 1 |
| Schaaf, HS | 1 |
| Visser, R | 1 |
| de Mast, Q | 1 |
| Netea-Maier, RT | 1 |
| van der Ven, AJ | 1 |
| Van Rossum, AM | 1 |
| Gaakeer, MI | 1 |
| Verweel, S | 1 |
| Hartwig, NG | 1 |
| Wolfs, TF | 1 |
| Geelen, SP | 1 |
| Lamberts, SW | 1 |
| de Groot, R | 1 |
| Collazos, J | 1 |
| Ibarra, S | 1 |
| Mayo, J | 1 |
| Jimenez, C | 1 |
| Moran, SA | 1 |
| Sereti, I | 1 |
| Wynne, S | 1 |
| Yen, PM | 1 |
| Falloon, J | 1 |
| Davey, RT | 1 |
| Sarlis, NJ | 1 |
| Madeddu, G | 2 |
| Spanu, A | 1 |
| Chessa, F | 1 |
| Calia, GM | 1 |
| Lovigu, C | 1 |
| Solinas, P | 1 |
| Mannazzu, M | 1 |
| Falchi, A | 1 |
| Mura, MS | 1 |
| Beltran, S | 1 |
| Lescure, FX | 1 |
| El Esper, I | 1 |
| Schmit, JL | 1 |
| Desailloud, R | 1 |
| Touzot, M | 1 |
| Beller, CL | 1 |
| Touzot, F | 1 |
| Louet, AL | 1 |
| Piketty, C | 1 |
| Afhami, S | 1 |
| Haghpanah, V | 1 |
| Heshmat, R | 1 |
| Rasoulinejad, M | 1 |
| Izadi, M | 1 |
| Lashkari, A | 1 |
| Tavangar, SM | 1 |
| Hajiabdolbaghi, M | 1 |
| Mohraz, M | 1 |
| Larijani, B | 1 |
| Olivieri, A | 1 |
| Sorcini, M | 1 |
| Battisti, P | 1 |
| Fazzini, C | 1 |
| Gilardi, E | 1 |
| Sun, Y | 1 |
| Medda, E | 1 |
| Grandolfo, M | 1 |
| Tossini, G | 1 |
| Natili, S | 1 |
| Grunfeld, C | 1 |
| Pang, M | 1 |
| Doerrler, W | 1 |
| Jensen, P | 1 |
| Shimizu, L | 1 |
| Feingold, KR | 1 |
| Cavalieri, RR | 1 |
| Schürmeyer, TH | 1 |
| Müller, V | 1 |
| von zur Mühlen, A | 1 |
| Schmidt, RE | 1 |
| Tseng, A | 1 |
| Fletcher, D | 1 |
| Jubault, V | 1 |
| Penfornis, A | 1 |
| Schillo, F | 1 |
| Hoen, B | 1 |
| Izembart, M | 1 |
| Timsit, J | 1 |
| Kazatchkine, MD | 1 |
| Gilquin, J | 1 |
| Viard, JP | 1 |
| Ball, SC | 1 |
| Nerad, JL | 1 |
| Kessler, HA | 1 |
| Rana, S | 1 |
| Nunlee-Bland, G | 1 |
| Valyasevi, R | 1 |
| Iqbal, M | 1 |
| Witzke, O | 1 |
| Winterhagen, T | 1 |
| Saller, B | 1 |
| Roggenbuck, U | 1 |
| Lehr, I | 1 |
| Philipp, T | 1 |
| Mann, K | 1 |
| Reinhardt, W | 1 |
| Lanzafame, M | 1 |
| Trevenzoli, M | 1 |
| Faggian, F | 1 |
| Marcati, P | 1 |
| Gatti, F | 1 |
| Carolo, G | 1 |
| Concia, E | 1 |
| Bourdoux, PP | 1 |
| De Wit, SA | 1 |
| Servais, GM | 1 |
| Clumeck, N | 1 |
| Bonnyns, MA | 1 |
| Lambert, M | 1 |
| Zech, F | 1 |
| De Nayer, P | 1 |
| Jamez, J | 1 |
| Vandercam, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Confirmation of Systemic Autoimmune Diseases in the Agricultural Health Study[NCT00341198] | 700 participants | Observational | 2002-04-02 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and HIV Coinfection
| Article | Year |
|---|---|
Probable interaction between levothyroxine and ritonavir: Case report and literature review.
Topics: Adult; Dose-Response Relationship, Drug; Drug Interactions; Female; HIV Infections; HIV Protease Inh | 2017 |
1 trial available for thyroxine and HIV Coinfection
| Article | Year |
|---|---|
Endocrinologic and immunologic factors associated with recovery of growth in children with human immunodeficiency virus type 1 infection treated with protease inhibitors.
Topics: Antiretroviral Therapy, Highly Active; Body Height; Body Mass Index; CD4 Lymphocyte Count; Child, Pr | 2003 |
32 other studies available for thyroxine and HIV Coinfection
| Article | Year |
|---|---|
Thyroid Function in Newly Diagnosed HIV-positive Patients.
Topics: Adult; Euthyroid Sick Syndromes; Female; HIV Infections; HIV Seropositivity; Humans; Hyperthyroidism | 2023 |
Impact of thyroid function abnormalities on reproductive hormones during menstrual cycle in premenopausal HIV infected females at NAUTH, Nnewi, Nigeria.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Est | 2017 |
Assessing endocrine and immune parameters in human immunodeficiency virus-infected patients before and after the immune reconstitution inflammatory syndrome.
Topics: Antiretroviral Therapy, Highly Active; Biomarkers; CD4-CD8 Ratio; Dehydroepiandrosterone Sulfate; En | 2018 |
Thyroid function among HIV/AIDS patients on highly active anti-retroviral therapy.
Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cross-Sectional Studies; F | 2010 |
Prevalence of thyroid dysfunction and its correlation with CD4 count in newly-diagnosed HIV-positive adults--a cross-sectional study.
Topics: Adult; Case-Control Studies; CD4 Lymphocyte Count; Cross-Sectional Studies; Enzyme-Linked Immunosorb | 2015 |
Thyroid screening in HIV-infected patients with antiretroviral therapy.
Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Retroviral Agents; Austria; Causality; Child; Comorb | 2015 |
[Thyroid dysfunction among HIV infected patients].
Topics: Adult; Aged; Antirheumatic Agents; CD4 Lymphocyte Count; Chile; Cross-Sectional Studies; Female; HIV | 2016 |
Thyroid function in multidrug-resistant tuberculosis patients with or without human immunodeficiency virus (HIV) infection before commencement of MDR-TB drug regimen.
Topics: Adult; Antitubercular Agents; Coinfection; Cross-Sectional Studies; Female; HIV Infections; Hospital | 2016 |
Early neuropsychological adverse events after switching from PI/r to dolutegravir could be related to hyperthyroidism in patients under levothyroxine.
Topics: Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Drug Substitution; | 2017 |
[Chorea during treatment with pegylated interferon and ribavirin in HIV-HCV coinfected patient].
Topics: Adult; Anti-HIV Agents; Antidepressive Agents; Antiviral Agents; Anxiety Disorders; Chorea; Citalopr | 2009 |
[Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone].
Topics: Administration, Inhalation; Adrenocorticotropic Hormone; Androstadienes; Blood Glucose; Bronchodilat | 2009 |
Abnormalities in the thyroid function tests as surrogate marker of advancing HIV infection in infected adults.
Topics: Adult; Biomarkers; CD4 Lymphocyte Count; Disease Progression; Epidemiologic Methods; Female; HIV Inf | 2009 |
Abnormal thyroid function tests in children on ethionamide treatment.
Topics: Adolescent; Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Ethionamide; Euthyr | 2011 |
Hashimoto's thyroiditis presenting as acute painful thyroiditis and as a manifestation of an immune reconstitution inflammatory syndrome in a human immunodeficiency virus-seropositive patient.
Topics: Adult; Anti-Retroviral Agents; Female; Hashimoto Disease; HIV Infections; Humans; Immune Reconstitut | 2012 |
Thyroid hormones in HIV-infected patients in the highly active antiretroviral therapy era: evidence of an interrelation between the thyroid axis and the immune system.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; | 2003 |
Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Antigens; Graves Disease; HIV Infections; Humans; Imm | 2004 |
Thyroid function in human immunodeficiency virus patients treated with highly active antiretroviral therapy (HAART): a longitudinal study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Autoantibodies; CD4 Lymphocyte Count; | 2006 |
Subclinical hypothyroidism in HIV-infected patients is not an autoimmune disease.
Topics: Adult; Antiretroviral Therapy, Highly Active; Autoantibodies; Autoimmune Diseases; HIV Infections; H | 2006 |
Dramatic interaction between levothyroxine and lopinavir/ritonavir in a HIV-infected patient.
Topics: Antiretroviral Therapy, Highly Active; Drug Interactions; Female; HIV Infections; HIV Protease Inhib | 2006 |
Assessment of the factors involving in the development of hypothyroidism in HIV-infected patients: a case-control study.
Topics: Adult; Age Factors; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Coun | 2007 |
Thyroid hypofunction related with the progression of human immunodeficiency virus infection.
Topics: Adult; Female; HIV Infections; Humans; Male; Middle Aged; Thyroid Gland; Thyrotropin; Thyroxine; Tri | 1993 |
Indices of thyroid function and weight loss in human immunodeficiency virus infection and the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Analysis of Variance; Eating; HIV Infections; Humans; Severity o | 1993 |
Endocrine testicular function in HIV-infected outpatients.
Topics: Adult; Aldosterone; Analysis of Variance; CD4 Lymphocyte Count; Chi-Square Distribution; Dehydroepia | 1997 |
Interaction between ritonavir and levothyroxine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Interactions; HIV Infections; Humans; Male; Riton | 1998 |
Sequential occurrence of thyroid autoantibodies and Graves' disease after immune restoration in severely immunocompromised human immunodeficiency virus-1-infected patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Autoantibodies; CD4 Lymphocyte Count | 2000 |
When HIV is not the only diagnosis.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; HIV Infectio | 2001 |
Hypercholesterolemia in a health care worker receiving thyroxine after postexposure prophylaxis for human immunodeficiency virus infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; Health Per | 2001 |
Thyroid dysfunction in HIV-infected children: is L-thyroxine therapy beneficial?
Topics: Child, Preschool; Drug Monitoring; Failure to Thrive; Female; Follow-Up Studies; HIV Infections; Hum | 1996 |
Transient stimulatory effects on pituitary-thyroid axis in patients treated with interleukin-2.
Topics: Adult; HIV Infections; Humans; Interleukin-2; Male; Pituitary Gland; Prospective Studies; Thyroid Gl | 2001 |
Interaction between levothyroxine and indinavir in a patient with HIV infection.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors | 2002 |
Biochemical thyroid profile in patients infected with the human immunodeficiency virus.
Topics: Adult; Aged; Antibodies; Female; HIV Infections; Humans; Male; Middle Aged; Thyroglobulin; Thyroid G | 1991 |
Elevation of serum thyroxine-binding globulin (but not of cortisol-binding globulin and sex hormone-binding globulin) associated with the progression of human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Carrier Proteins; Female; HIV Infections; HIV Serop | 1990 |