thyroxine has been researched along with Growth Disorders in 128 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Growth Disorders: Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Children with Fanconi anemia (FA) tend to have short stature, mild thyrotropin (TSH) elevation, and borderline low free thyroxine (FT4)." | 5.13 | Improved growth velocity during thyroid hormone therapy in children with Fanconi anemia and borderline thyroid function. ( Blum, S; Eyal, O; Mueller, R; Rose, SR; Smith, FO, 2008) |
| "We studied the clinical and hormonal profiles of patients with central hypothyroidism (CH), the adequacy of levothyroxine (L-T4) treatment and the influence of other pituitary hormone replacement therapies." | 3.72 | Clinical and hormonal characteristics of central hypothyroidism at diagnosis and during follow-up in adult patients. ( Alexopoulou, O; Beguin, C; De Nayer, P; Maiter, D, 2004) |
| " The purpose of our investigation was to test the relationship between the production of the growth factor somatomedin C (insulin growth factor-1) and the thyroxine level in children with congenital hypothyroidism revealed during neonatal screening." | 3.69 | [Growth in children with impairment of thyroid gland function]. ( Hníková, O, 1995) |
| "Prolonged juvenile hypothyroidism results in a permanent loss in height that is related to the duration of thyroxine deficiency before adequate thyroxine replacement treatment." | 3.69 | Attainment of normal height in severe juvenile hypothyroidism. ( Minamitani, K; Murata, A; Niimi, H; Ohnishi, H; Wataki, K; Yasuda, T, 1994) |
| "This report presents an analysis of four patients who suffered from longstanding untreated hypothyroidism, with special attention to the phase of catch-up growth after the start of L-thyroxine treatment." | 3.69 | Catch-up growth after prolonged hypothyroidism. ( Boersma, B; Otten, BJ; Stoelinga, GB; Wit, JM, 1996) |
| " Administration of up to 900 mug of thyroxine or 225 mug of triiodothyronine led to minimal changes in urinary hydroxyproline excretion, pulse rate and body weight." | 3.65 | Peripheral resistance to thyroxine: a cause of short stature in a boy without goitre. ( Bardin, CW; Keiser, HR; Schneider, G, 1975) |
| "Undernutrition is a stressor with long-term consequences, and the effect of nutritional recovery on cortisol and thyroid hormone status is unknown." | 2.82 | Normal cortisol response to cold pressor test, but lower free thyroxine, after recovery from undernutrition. ( Clemente, AP; de Albuquerque, MP; Garcia, MC; Hoffman, DJ; Martins, VJ; Neves, AP; Sawaya, AL; Spadari, RC, 2016) |
| "Isolated central hypothyroidism has been considered rare." | 2.68 | Isolated central hypothyroidism in short stature. ( Rose, SR, 1995) |
| "In developing country like ours if treatment of hypothyroidism can be started even by 6 months of age considerable brain function can be salvaged so that they can attain a self supportive life." | 2.68 | Treating congenital hypothyroidism: maximum age limit up to which a socially compatible child is expected. ( Chakrabartty, S; Kundu, R, 1996) |
| "A total of 14 neoplasms were diagnosed (191/100,000 PY); 7 out of 9 malignancies were recurrent craniopharyngioma found in patients with organic GHD." | 1.51 | Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study. ( Chae, HW; Choi, JH; Chung, S; Hwang, IT; Kim, EY; Kim, HS; Kim, JH; Rhie, YJ; Shin, CH; Yoo, JH, 2019) |
| "They were treated for hypothyroidism but their growth did not improve as expected." | 1.43 | 45,X/46,XY Mosaicism and Possible Association With Hypothyroidism in Males. ( Hojat, L; Schweiger, M, 2016) |
| "His longstanding CH was associated with empty sella syndrome, static encephalopathy, and severe musculoskeletal deformities." | 1.43 | Case Report: The Specter of Untreated Congenital Hypothyroidism in Immigrant Families. ( Drilling, A; Fischer, M; Hamdoun, E; Karachunski, P; Nathan, B; Petryk, A; Torkelson, JL, 2016) |
| "We report on three cases of autoimmune thyroiditis (AT) in young children who presented with constipation, decreased appetite, and increased hours of sleep." | 1.39 | Rare cases of autoimmune hypothyroidism in young children. ( Caiulo, S; Chiumello, G; Di Frenna, M; Tronconi, GM; Vigone, MC; Weber, G, 2013) |
| "He was diagnosed with atrophic autoimmune thyroiditis." | 1.37 | A 5-year-old boy with atrophic autoimmune thyroiditis caused by thyroid-stimulation blocking antibodies. ( Inamo, Y, 2011) |
| "Before GH treatment, 159 patients had treated central hypothyroidism (treated group) while 84 patients were considered euthyroid (untreated group)." | 1.34 | Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patients. ( Agha, A; Chew, SL; Drake, WM; Grossman, AB; Jenkins, PJ; Monson, JP; Perry, L; Walker, D, 2007) |
| "A case of primary hypothyroidism in a pre-pubertal girl presenting with vaginal bleeding and unilateral ovarian cyst is reported." | 1.33 | Ovarian cyst in juvenile hypothyroidism. ( Ammini, AC; Kriplani, A; Singh, BM, 2005) |
| "The hypothyroidism is a frequent endocrinopathos." | 1.31 | [Hypothyroidism in children. 82 cases]. ( Ben Amar, H; Ben Slimen, M; Hachicha, M; Kolsi, S; Loulou, F; Mahfoudh, A; Rekik, S; Triki, A, 2002) |
| " Our data demonstrate that GH treatment of thalassemic children with normal GH reserve and low serum IGF-I concentrations with supraphysiological doses of rhGH for one year can cause a significant increase in serum IGF-I levels and growth velocity, but it remains to be elucidated whether long-term administration will affect the final height." | 1.31 | Growth hormone treatment in short children with beta-thalassemia major. ( Athanasiou-Metaxa, M; Harsoulis, F; Katzos, G; Papakostantinou-Athanasiadou, E, 2000) |
| "The effects of GH therapy on thyroid function among previous reports have shown remarkable discrepancies, probably due to differences in hormone assay methods, degree of purification of former pituitary-derived GH preparations, dosage schedules, diagnostic criteria, patient selection, duration of treatment and study design." | 1.31 | Changes in serum thyroid hormones levels and their mechanisms during long-term growth hormone (GH) replacement therapy in GH deficient children. ( Abucham, J; MacCagnan, P; Oliveira, JH; Portes, ES, 2000) |
| "Hypothyroidism was not present in our iron overloaded thalassaemic patients." | 1.30 | Thyroid function in thalassaemia major. ( Hubert, HD; Senanayake, MP; Suraweera, SA, 1999) |
| "We studied 45 prepubertal children with IDDM (30 males, 15 females) over 1 year period." | 1.29 | Growth parameters, growth hormone (GH) response to clonidine and circulating insulin-like growth factor-I (IGF-I), free thyroxine (FT4) and cortisol concentrations in relation to glycaemic control in children with insulin-dependent diabetes mellitus. ( Ahmed, HI; Asfour, MG; Soliman, AT, 1996) |
| "Graves' disease in a girl with Turner's syndrome (karyotype 46,Xdel(Xp)) is described." | 1.28 | Hyperthyroidism accelerates growth in Turner's syndrome. ( de Zegher, F; Dooms, L; Massa, G; Vanderschueren-Lodeweyckx, M, 1992) |
| "Our data suggest that juvenile primary hypothyroidism results in a permanent height deficit." | 1.28 | Growth prognosis and growth after menarche in primary hypothyroidism. ( Grant, DB; Pantsiouou, S; Preece, MA; Stanhope, R; Uruena, M, 1991) |
| "A case of juvenile hypothyroidism is presented showing evidence of delayed shedding of deciduous teeth, root development, eruption of permanent teeth as well as retarded skeletal growth." | 1.28 | Dental and skeletal changes in juvenile hypothyroidism following treatment: case report. ( Chindia, ML; Mg'ang'a, PM, 1990) |
| "Both had a history of intrauterine growth retardation (IUGR), but showed an appropriate growth rate after infancy (5 cm/y)." | 1.28 | Euthyroid hypothyrotropinemia in children of short stature. ( Hashimoto, H; Miyagawa, K; Sato, T; Sonoda, T, 1989) |
| "A series of 14 children with Crohn's disease and growth retardation was screened for endocrine dysfunction." | 1.27 | Endocrine dysfunction in children with Crohn's disease. ( Chong, SK; Grossman, A; Rees, LH; Walker-Smith, JA, 1984) |
| "Nine patients with Turner's syndrome aged 7 to 13 years were treated with recombinant human growth hormone (hGH) at a dose of 0." | 1.27 | Factors attenuating growth promoting effect of growth hormone therapy for Turner's syndrome. ( Kajiwara, S; Miyagawa, K; Miyamori, C; Sato, T; Shimizu, M, 1988) |
| " After long-term administration of nitrate a significant decrease of serum somatomedin activity was found which also showed a positive correlation with a decrease of body weight gain." | 1.27 | Growth impairment caused by dietary nitrate intake regulated via hypothyroidism and decreased somatomedin. ( Hesse, V; Jahreis, G; Lüdke, H; Schöne, F, 1987) |
| "Failure to recognize and treat hypothyroidism in these pubertal patients may compromise the adult height, since skeletal maturation will proceed under the influence of sex hormones despite the presence of hypothyroidism." | 1.26 | Clinical recognition of juvenile hypothyroidism in the early stage. ( Abbassi, V; Cancellieri, RP; Rigterink, E, 1980) |
| "Compensated hypothyroidism is frequent in cystinosis and may be one factor in the severe growth retardation in this condition." | 1.26 | [Thyroid involvement in cystinosis]. ( Broyer, M; Czernichow, P; Lenoir, G; Rappaport, R; Roy, MP, 1978) |
| " The mean height velocity attained at the optimal dosage (0." | 1.25 | Medical Research Council of Canada therapeutic trial of human growth hormone: first 5 years of therapy. ( Bailey, JD; Beck, JC; Friesen, H; Guyda, H; Leboeuf, G, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (34.38) | 18.7374 |
| 1990's | 33 (25.78) | 18.2507 |
| 2000's | 28 (21.88) | 29.6817 |
| 2010's | 19 (14.84) | 24.3611 |
| 2020's | 4 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Erbaş, İM | 1 |
| Demir, K | 1 |
| Doknic, M | 1 |
| Gasic, V | 1 |
| Stojanovic, M | 1 |
| Pavlovic, S | 1 |
| Marinkovic, S | 1 |
| Miljic, D | 1 |
| Pekic, S | 1 |
| Manojlovic-Gacic, E | 1 |
| Damjanovic, D | 1 |
| Soldatovic, I | 1 |
| Petakov, M | 1 |
| Adamczewska, K | 1 |
| Adamczewski, Z | 1 |
| Łupińska, A | 1 |
| Lewiński, A | 1 |
| Stawerska, R | 1 |
| Zhang, W | 1 |
| Qian, F | 1 |
| Lu, G | 1 |
| Wu, Y | 1 |
| Li, R | 1 |
| Xia, L | 1 |
| Zhao, R | 1 |
| Lin, Y | 1 |
| Gu, M | 1 |
| Chen, W | 1 |
| Wang, W | 1 |
| Jiang, S | 1 |
| Cui, Z | 1 |
| Luo, X | 1 |
| Shi, L | 1 |
| Zheng, H | 1 |
| Rhie, YJ | 1 |
| Yoo, JH | 1 |
| Choi, JH | 1 |
| Chae, HW | 1 |
| Kim, JH | 1 |
| Chung, S | 1 |
| Hwang, IT | 1 |
| Shin, CH | 1 |
| Kim, EY | 1 |
| Kim, HS | 1 |
| Tronconi, GM | 1 |
| Caiulo, S | 1 |
| Di Frenna, M | 1 |
| Vigone, MC | 1 |
| Chiumello, G | 1 |
| Weber, G | 1 |
| García, RJ | 1 |
| Iñiguez, G | 1 |
| Gaete, X | 1 |
| Linares, J | 1 |
| Ocaranza, P | 1 |
| Avila, A | 1 |
| Roman, R | 1 |
| Cassorla, F | 1 |
| Hojat, L | 1 |
| Schweiger, M | 1 |
| Valsesia, A | 1 |
| Chatelain, P | 1 |
| Stevens, A | 1 |
| Peterkova, VA | 1 |
| Belgorosky, A | 1 |
| Maghnie, M | 1 |
| Antoniazzi, F | 1 |
| Koledova, E | 1 |
| Wojcik, J | 1 |
| Farmer, P | 1 |
| Destenaves, B | 1 |
| Clayton, P | 1 |
| Martins, VJ | 1 |
| Neves, AP | 1 |
| Garcia, MC | 1 |
| Spadari, RC | 1 |
| Clemente, AP | 1 |
| de Albuquerque, MP | 1 |
| Hoffman, DJ | 1 |
| Sawaya, AL | 1 |
| Gaspari, L | 1 |
| Paris, F | 1 |
| Leboucq, N | 1 |
| Bonafé, A | 1 |
| Sultan, C | 1 |
| Hamdoun, E | 1 |
| Karachunski, P | 1 |
| Nathan, B | 1 |
| Fischer, M | 1 |
| Torkelson, JL | 1 |
| Drilling, A | 1 |
| Petryk, A | 1 |
| Salerno, M | 1 |
| Capalbo, D | 1 |
| Cerbone, M | 1 |
| De Luca, F | 2 |
| Kim, SJ | 1 |
| Yoon, JH | 1 |
| Kim, HK | 1 |
| Kang, HC | 1 |
| Starzyk, J | 1 |
| Wójcik, M | 1 |
| Eyal, O | 1 |
| Blum, S | 1 |
| Mueller, R | 1 |
| Smith, FO | 1 |
| Rose, SR | 3 |
| Kumar, KV | 1 |
| Muthukrishnan, J | 1 |
| Sinha, R | 1 |
| Modi, KD | 1 |
| Diamanti, A | 1 |
| Ferretti, F | 1 |
| Guglielmi, R | 1 |
| Panetta, F | 1 |
| Colistro, F | 1 |
| Cappa, M | 1 |
| Daniele, A | 1 |
| Sole Basso, M | 1 |
| Noto, C | 1 |
| Crisogianni, M | 1 |
| Castro, M | 1 |
| Hokken-Koelega, AC | 1 |
| Mathew, RP | 1 |
| Kovacs, WJ | 1 |
| Inamo, Y | 1 |
| Bochukova, E | 1 |
| Schoenmakers, N | 1 |
| Agostini, M | 1 |
| Schoenmakers, E | 1 |
| Rajanayagam, O | 1 |
| Keogh, JM | 1 |
| Henning, E | 1 |
| Reinemund, J | 1 |
| Gevers, E | 1 |
| Sarri, M | 1 |
| Downes, K | 1 |
| Offiah, A | 1 |
| Albanese, A | 1 |
| Halsall, D | 1 |
| Schwabe, JW | 1 |
| Bain, M | 1 |
| Lindley, K | 1 |
| Muntoni, F | 1 |
| Vargha-Khadem, F | 1 |
| Khadem, FV | 1 |
| Dattani, M | 1 |
| Farooqi, IS | 1 |
| Gurnell, M | 1 |
| Chatterjee, K | 1 |
| Grasberger, H | 1 |
| De Deken, X | 1 |
| Mayo, OB | 1 |
| Raad, H | 1 |
| Weiss, M | 1 |
| Liao, XH | 1 |
| Refetoff, S | 1 |
| Nebesio, TD | 1 |
| Wise, MD | 1 |
| Perkins, SM | 1 |
| Eugster, EA | 1 |
| Monk, JA | 1 |
| Sims, NA | 1 |
| Dziegielewska, KM | 1 |
| Weiss, RE | 1 |
| Ramsay, RG | 1 |
| Richardson, SJ | 1 |
| Beltroy, E | 1 |
| Umpaichitra, V | 1 |
| Gordon, S | 1 |
| Castells, S | 1 |
| O'Connor, K | 1 |
| Gomez, R | 1 |
| Knoebel, E | 1 |
| Liu, JH | 1 |
| Yi, ZW | 1 |
| Friedrichsen, S | 1 |
| Christ, S | 1 |
| Heuer, H | 1 |
| Schäfer, MK | 1 |
| Mansouri, A | 1 |
| Bauer, K | 1 |
| Visser, TJ | 2 |
| Hachicha, M | 1 |
| Mahfoudh, A | 1 |
| Loulou, F | 1 |
| Ben Amar, H | 1 |
| Kolsi, S | 1 |
| Ben Slimen, M | 1 |
| Rekik, S | 1 |
| Triki, A | 1 |
| Alexopoulou, O | 1 |
| Beguin, C | 1 |
| De Nayer, P | 1 |
| Maiter, D | 1 |
| Singh, BM | 1 |
| Ammini, AC | 1 |
| Kriplani, A | 1 |
| Karges, B | 1 |
| LeHeup, B | 1 |
| Schoenle, E | 1 |
| Castro-Correia, C | 1 |
| Fontoura, M | 1 |
| Pfäffle, R | 1 |
| Andler, W | 1 |
| Debatin, KM | 1 |
| Karges, W | 1 |
| van Buul-Offers, SC | 1 |
| Smink, JJ | 1 |
| Gresnigt, R | 1 |
| Hamers, N | 1 |
| Koedam, J | 1 |
| Karperien, M | 1 |
| Williams, FL | 1 |
| Mires, GJ | 1 |
| Barnett, C | 1 |
| Ogston, SA | 1 |
| van Toor, H | 1 |
| Hume, R | 1 |
| Quintos, JB | 1 |
| Salas, M | 1 |
| Joergensen, JV | 1 |
| Oerbeck, B | 1 |
| Jebsen, P | 1 |
| Heyerdahl, S | 2 |
| Kase, BF | 2 |
| Polak, M | 1 |
| Agha, A | 1 |
| Walker, D | 1 |
| Perry, L | 1 |
| Drake, WM | 1 |
| Chew, SL | 1 |
| Jenkins, PJ | 1 |
| Grossman, AB | 1 |
| Monson, JP | 1 |
| Bossowski, AT | 1 |
| Reddy, V | 1 |
| Perry, LA | 1 |
| Johnston, LB | 1 |
| Banerjee, K | 1 |
| Blair, JC | 1 |
| Savage, MO | 1 |
| Fedi, M | 1 |
| Bach, LA | 1 |
| Berkovic, SF | 1 |
| Willoughby, JO | 1 |
| Scheffer, IE | 1 |
| Reutens, DC | 1 |
| Chong, SK | 1 |
| Grossman, A | 1 |
| Walker-Smith, JA | 1 |
| Rees, LH | 1 |
| Huseman, CA | 2 |
| Hassing, JM | 2 |
| Labbe, A | 1 |
| Dubray, C | 1 |
| Gaillard, G | 1 |
| Besse, G | 1 |
| Assali, P | 1 |
| Malpuech, G | 1 |
| Fisher, JN | 1 |
| Abbassi, V | 1 |
| Rigterink, E | 1 |
| Cancellieri, RP | 1 |
| Soliman, AT | 3 |
| Mohsin, N | 1 |
| al Hasani, M | 1 |
| Elbualy, M | 1 |
| Tomita, K | 1 |
| Yoshida, T | 1 |
| Morita, J | 1 |
| Atsumi, S | 1 |
| Totsuka, T | 1 |
| Hníková, O | 1 |
| Yamamoto, T | 2 |
| Matsuo, S | 1 |
| Ueshima, Y | 1 |
| Inoue, F | 1 |
| Kinugasa, A | 1 |
| Sawada, T | 1 |
| Kaplowitz, P | 1 |
| Webb, J | 1 |
| Minamitani, K | 1 |
| Murata, A | 1 |
| Ohnishi, H | 1 |
| Wataki, K | 1 |
| Yasuda, T | 1 |
| Niimi, H | 1 |
| Grant, DB | 2 |
| Paternostro, MA | 1 |
| Meisami, E | 1 |
| Dacou-Voutetakis, C | 1 |
| Kitra, V | 1 |
| Grafakos, S | 1 |
| Polychronopoulou, S | 1 |
| Drakopoulou, M | 1 |
| Haidas, S | 1 |
| Burman, P | 1 |
| Hetta, J | 1 |
| Wide, L | 1 |
| Månsson, JE | 1 |
| Ekman, R | 1 |
| Karlsson, FA | 1 |
| Boersma, B | 1 |
| Otten, BJ | 1 |
| Stoelinga, GB | 1 |
| Wit, JM | 1 |
| Saenger, P | 1 |
| Attie, KM | 1 |
| DiMartino-Nardi, J | 1 |
| Fine, RN | 1 |
| Kundu, R | 1 |
| Chakrabartty, S | 1 |
| Ahmed, HI | 1 |
| Asfour, MG | 1 |
| Evliyaoğlu, N | 1 |
| Kilinç, Y | 1 |
| Sargin, O | 1 |
| Takamatsu, J | 1 |
| Ito, M | 1 |
| Yamano, Y | 1 |
| Fukao, T | 1 |
| Sakane, S | 1 |
| Ohsawa, N | 1 |
| Ilicki, A | 1 |
| Karlberg, J | 1 |
| Larsson, A | 1 |
| Takano, S | 1 |
| Kanzaki, S | 1 |
| Sato, M | 1 |
| Kubo, T | 1 |
| Seino, Y | 1 |
| de Boer, JA | 1 |
| Schoemaker, J | 1 |
| van der Veen, EA | 1 |
| Krekmanova, L | 1 |
| Carlstedt-Duke, J | 1 |
| Brönnegård, M | 1 |
| Marcus, C | 1 |
| Gröndahl, E | 1 |
| Modéer, T | 1 |
| Dahllöf, G | 1 |
| Vicens-Calvet, E | 1 |
| Seijo, G | 1 |
| Potau, N | 1 |
| de los Llanos Moreno, M | 1 |
| Carrascosa, A | 1 |
| Katzos, G | 1 |
| Papakostantinou-Athanasiadou, E | 1 |
| Athanasiou-Metaxa, M | 1 |
| Harsoulis, F | 1 |
| Westwood, ME | 1 |
| Butler, GE | 1 |
| McLellan, AC | 1 |
| Barth, JH | 1 |
| Senanayake, MP | 1 |
| Suraweera, SA | 1 |
| Hubert, HD | 1 |
| Portes, ES | 1 |
| Oliveira, JH | 1 |
| MacCagnan, P | 1 |
| Abucham, J | 1 |
| Hornick, JL | 1 |
| Van Eenaeme, C | 1 |
| Gérard, O | 1 |
| Dufrasne, I | 1 |
| Istasse, L | 1 |
| Dupuis-Girod, S | 1 |
| Gluckman, E | 1 |
| Souberbielle, JC | 1 |
| Brauner, R | 1 |
| Madkour, A | 1 |
| Galil, MA | 1 |
| El Zalabany, M | 1 |
| Aziz, SM | 1 |
| Ansari, BM | 1 |
| Hasan, W | 1 |
| Cowen, T | 1 |
| Barnett, PS | 1 |
| Elliot, E | 1 |
| Coskeran, P | 1 |
| Bouloux, PM | 1 |
| Mehrotra, P | 1 |
| Chandra, M | 1 |
| Mitra, MK | 1 |
| Quevedo, MF | 1 |
| Pironis, B | 1 |
| Palese, T | 1 |
| Counts, DR | 1 |
| Arii, J | 1 |
| Tanabe, Y | 1 |
| Makino, M | 1 |
| Sato, H | 1 |
| Kohno, Y | 1 |
| Borut, D | 1 |
| Kogut, MD | 1 |
| Guyda, H | 1 |
| Friesen, H | 1 |
| Bailey, JD | 1 |
| Leboeuf, G | 1 |
| Beck, JC | 1 |
| Schneider, G | 1 |
| Keiser, HR | 1 |
| Bardin, CW | 1 |
| Zuppinger, KA | 2 |
| Joss, EE | 2 |
| König, MP | 1 |
| Staub, JJ | 1 |
| Girard, J | 2 |
| Ehrengruber, H | 1 |
| Raiti, S | 1 |
| Trias, E | 1 |
| Maclaren, NK | 1 |
| Madeddu, G | 1 |
| Dore, A | 1 |
| Marongiu, A | 1 |
| Langer-Costanzi, M | 1 |
| Tonini, G | 1 |
| Tecilazich, D | 1 |
| Bertoli, G | 1 |
| Di Giacomo, BE | 1 |
| Mangiarotti Marchi, MA | 1 |
| Nordio, S | 1 |
| Marelli, R | 1 |
| Burstein, PJ | 1 |
| Draznin, B | 1 |
| Johnson, CJ | 1 |
| Schalch, DS | 1 |
| Winter, RJ | 1 |
| Thompson, RG | 1 |
| Green, OC | 1 |
| Parks, JS | 1 |
| Tenore, A | 1 |
| Bongiovanni, AM | 1 |
| Kirkland, RT | 1 |
| Teixeira, D | 1 |
| Guimaräes, A | 1 |
| Rino, W | 1 |
| Muniz, J | 1 |
| Czernichow, P | 1 |
| Lenoir, G | 1 |
| Roy, MP | 1 |
| Rappaport, R | 1 |
| Broyer, M | 1 |
| Daughaday, WH | 1 |
| Herington, AC | 1 |
| Phillips, LS | 1 |
| Herman, SP | 1 |
| Burgert, EO | 1 |
| Lightner, ES | 1 |
| Penny, R | 1 |
| Frasier, SD | 1 |
| Zuppinger, K | 1 |
| Joss, E | 1 |
| Locher, A | 1 |
| Rotter, A | 1 |
| Zurbrügg, R | 1 |
| Matsubara, K | 1 |
| Suzuki, K | 1 |
| Lin, YW | 1 |
| Ohta, S | 1 |
| Massa, G | 1 |
| de Zegher, F | 1 |
| Dooms, L | 1 |
| Vanderschueren-Lodeweyckx, M | 1 |
| Municchi, G | 1 |
| Malozowski, S | 1 |
| Nisula, BC | 1 |
| Cristiano, A | 1 |
| Carta, S | 1 |
| Grandolfo, ME | 1 |
| Moschini, L | 1 |
| Olivieri, A | 1 |
| Stazi, A | 1 |
| Fazzini, C | 1 |
| Battisti, P | 1 |
| Timperi, F | 1 |
| Sorcini, M | 1 |
| Pantsiouou, S | 1 |
| Stanhope, R | 1 |
| Uruena, M | 1 |
| Preece, MA | 1 |
| Hammond, AC | 1 |
| Elsasser, TH | 1 |
| Olson, TA | 1 |
| Hindmarsh, PC | 1 |
| Pringle, PJ | 1 |
| Di Silvio, L | 1 |
| Brook, CG | 1 |
| Chen, GW | 1 |
| Huang, HS | 1 |
| Wang, PW | 1 |
| Lin, JD | 1 |
| Huang, BY | 1 |
| Huang, MJ | 1 |
| Mg'ang'a, PM | 1 |
| Chindia, ML | 1 |
| Randolph, JF | 1 |
| Miller, CL | 1 |
| Cummings, JF | 1 |
| Lothrop, CD | 1 |
| Moreno, L | 1 |
| Ythier, H | 1 |
| Loeuille, GA | 1 |
| Lebecq, MF | 1 |
| Dhondt, JL | 1 |
| Farriaux, JP | 1 |
| Sato, T | 2 |
| Hashimoto, H | 1 |
| Miyagawa, K | 2 |
| Sonoda, T | 1 |
| Gómez-Pan, A | 1 |
| Rodríguez-Arnao, MD | 1 |
| Sibilia, MG | 1 |
| Miyamori, C | 1 |
| Kajiwara, S | 1 |
| Shimizu, M | 1 |
| Farley, JD | 1 |
| Toth, EL | 1 |
| Ryan, EA | 1 |
| Jahreis, G | 1 |
| Schöne, F | 1 |
| Lüdke, H | 1 |
| Hesse, V | 1 |
| Bessho, F | 1 |
| Saggese, G | 1 |
| Federico, G | 1 |
| Man, EB | 1 |
| Jones, WS | 1 |
| Holden, RH | 1 |
| Mellits, ED | 1 |
| Lippe, BM | 1 |
| Crandall, BF | 1 |
| Hamilton, W | 1 |
| Krieger, I | 1 |
| Good, MH | 1 |
| Mosier, HD | 1 |
| Smith, FG | 1 |
| Schultz, MA | 1 |
| Lehr, HJ | 1 |
| Werner, H | 1 |
| Rudorff, KH | 1 |
| Herrmann, J | 1 |
| Lee, PA | 1 |
| Blizzard, RM | 1 |
| Root, AW | 1 |
| Snyder, PJ | 1 |
| Rezvani, I | 1 |
| DiGeorge, AM | 1 |
| Utiger, RD | 1 |
| Rodriguez, JM | 1 |
| Shahidi, NT | 1 |
| Loening, WE | 1 |
| Vinik, AI | 1 |
| Olin, P | 1 |
| Kobielowa, Z | 1 |
| Szybiński, Z | 1 |
| Gumiński, T | 1 |
| Tarnawski, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Observational Long-term Follow-up of the Phase IV Open-label Trial of Predictive Markers in GHD and TS Pre-pubertal Children Treated With Saizen[NCT00699855] | 182 participants (Actual) | Observational | 2008-09-30 | Completed | |||
| A Phase IV Open-label Study of Predictive Markers in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children Treated With SAIZEN®[NCT00256126] | Phase 4 | 318 participants (Actual) | Interventional | 2005-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | Units per liter (U/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 21.13 |
| Growth Hormone Deficiency (GHD) | 14.78 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | millimoles per liter (mmol/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 0.22 |
| Growth Hormone Deficiency (GHD) | 0.13 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | picomole per liter (pmol/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 47.7 |
| Growth Hormone Deficiency (GHD) | 26.9 |
HOMA-IR is used to assess insulin resistance and calculated by an empirical mathematical formula based on fasting plasma glucose and fasting plasma insulin levels. HOMA-IR = fasting plasma insulin (picomole/liter [pmol/L]) * fasting plasma glucose (millimole/liter [mmol/L]) divided by 22.5. (NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | picomole per liter *millimole per liter (Mean) |
|---|---|
| Turner Syndrome (TS) | 2.132 |
| Growth Hormone Deficiency (GHD) | 1.061 |
IGF-1 SDS was calculated using the Elmlinger reference method. Change in within subject IGF-1 levels (standard deviation scores) at Month 1 from Baseline was assessed. Descriptive statistics were determined for the Baseline and Month 1 assessments, and also for the level of change between these two assessments. If either the Baseline or Month 1 IGF-1 level was missing, then the within-subject change in IGF-1 was assumed to be missing. (NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | Standard deviation score (SDS) (Mean) |
|---|---|
| Turner Syndrome (TS) | 1.7692 |
| Growth Hormone Deficiency (GHD) | 1.4007 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | milligram per liter (mg/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 0.86 |
| Growth Hormone Deficiency (GHD) | 0.69 |
9 reviews available for thyroxine and Growth Disorders
| Article | Year |
|---|---|
The Clinical Spectrum of Resistance to Thyroid Hormone Alpha in Children and Adults
Topics: Adult; Autism Spectrum Disorder; Child; Constipation; Developmental Disabilities; Growth Disorders; | 2021 |
Pituitary stalk interruption syndrome: A rare case report and literature review.
Topics: Adrenocorticotropic Hormone; Glucose Tolerance Test; Growth Disorders; Humans; Hydrocortisone; Hypog | 2020 |
Subclinical hypothyroidism in childhood - current knowledge and open issues.
Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic; | 2016 |
[Hypothyroidism in child].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Congenital Hypothyroidism; Consanguinity; F | 2005 |
Mechanisms of reduced and compensatory growth.
Topics: Animals; Body Composition; Cattle; Eating; Female; Growth Disorders; Growth Hormone; Insulin; Insuli | 2000 |
[Aspects of the hypothalamo-hypophyseal function in children].
Topics: Adolescent; Arginine; Calcium; Child; Clomiphene; Gonadotropins; Growth Disorders; Growth Hormone; H | 1979 |
The regulation of growth by endocrines.
Topics: Adrenal Cortex Hormones; Animals; Body Weight; Cartilage; Dwarfism, Pituitary; Endocrine Glands; Glu | 1975 |
[Congenital hypothyroidism: organization and coordination of neonatal screening in Italy].
Topics: Congenital Hypothyroidism; Fetal Blood; Fetus; Follow-Up Studies; Growth Disorders; Humans; Hypothal | 1991 |
[Juvenile hypothyroidism].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Growth Disorders; Humans; Hypothyroidism; Infant | 1985 |
11 trials available for thyroxine and Growth Disorders
| Article | Year |
|---|---|
Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children during therapy with recombinant human growth hormone.
Topics: Child; Female; Growth Disorders; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; R | 2018 |
Effects of levothyroxine on growth hormone (gh) sensitivity in children with idiopathic short stature.
Topics: Body Height; Child; Growth Disorders; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Th | 2014 |
Normal cortisol response to cold pressor test, but lower free thyroxine, after recovery from undernutrition.
Topics: Adolescent; Area Under Curve; Child; Cold Temperature; Cross-Sectional Studies; Female; Growth Disor | 2016 |
Improved growth velocity during thyroid hormone therapy in children with Fanconi anemia and borderline thyroid function.
Topics: Child; Child, Preschool; Cross-Over Studies; Double-Blind Method; Fanconi Anemia; Female; Growth; Gr | 2008 |
Clinical and endocrine features and long-term outcome of Graves' disease in early childhood.
Topics: Age of Onset; Antithyroid Agents; Attention Deficit Disorder with Hyperactivity; Carbimazole; Child; | 2007 |
Isolated central hypothyroidism in short stature.
Topics: Analysis of Variance; Child; Circadian Rhythm; Female; Growth Disorders; Humans; Hypothyroidism; Mal | 1995 |
Growth hormone treatment affects brain neurotransmitters and thyroxine [see comment].
Topics: Adult; Aspartic Acid; Cross-Over Studies; Double-Blind Method; Female; Growth Disorders; Growth Horm | 1996 |
Carbohydrate metabolism in children receiving growth hormone for 5 years. Chronic renal insufficiency compared with growth hormone deficiency, Turner syndrome, and idiopathic short stature. Genentech Collaborative Group.
Topics: Blood Glucose; Carbohydrate Metabolism; Child; Cholesterol; Glycated Hemoglobin; Growth Disorders; G | 1996 |
Treating congenital hypothyroidism: maximum age limit up to which a socially compatible child is expected.
Topics: Activities of Daily Living; Age Factors; Child, Preschool; Congenital Hypothyroidism; Female; Follow | 1996 |
The sweating apparatus in growth hormone deficiency, following treatment with r-hGH and in acromegaly.
Topics: Acetylcholinesterase; Acromegaly; Adult; Antigens, Differentiation; Biopsy; Female; Growth Disorders | 2001 |
TSH secretory pattern and thyroid function in children with growth hormone neurosecretory dysfunction.
Topics: Bone Development; Child; Child, Preschool; Female; Growth Disorders; Human Growth Hormone; Humans; M | 2002 |
108 other studies available for thyroxine and Growth Disorders
| Article | Year |
|---|---|
Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the effects of growth hormone replacement introduction in middle adulthood.
Topics: Absorptiometry, Photon; Adult; Body Composition; Bone Density; Bone Diseases, Metabolic; Brain Neopl | 2020 |
Strong Positive Correlation between TSH and Ghrelin in Euthyroid Non-Growth Hormone-Deficient Children with Short Stature.
Topics: Body Height; Child; Child, Preschool; Female; Ghrelin; Growth Disorders; Human Growth Hormone; Human | 2020 |
Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study.
Topics: Adolescent; Blood Glucose; Body Height; Child; Child, Preschool; Female; Follow-Up Studies; Glycated | 2019 |
Rare cases of autoimmune hypothyroidism in young children.
Topics: Appetite; Child, Preschool; Constipation; Delayed Diagnosis; Drug Monitoring; Fatigue; Female; Growt | 2013 |
45,X/46,XY Mosaicism and Possible Association With Hypothyroidism in Males.
Topics: Body Height; Child; Growth Disorders; Growth Hormone; Humans; Hypothyroidism; Male; Mosaicism; Thyro | 2016 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
Reversible growth failure and complete GH deficiency in a 4-year-old girl with very early Hashimoto's thyroiditis and subsequent hyperplasia of pituitary thyrotroph cells.
Topics: Brain; Child, Preschool; Female; Growth Disorders; Growth Hormone; Hashimoto Disease; Humans; Hyperp | 2016 |
Case Report: The Specter of Untreated Congenital Hypothyroidism in Immigrant Families.
Topics: Adolescent; Brain Diseases; Child; Cognition Disorders; Congenital Hypothyroidism; Delayed Diagnosis | 2016 |
Spontaneous ovarian hyperstimulation syndrome in a young female subject with a lingual thyroid and primary hypothyroidism.
Topics: Adolescent; Female; Growth Disorders; Hormone Replacement Therapy; Humans; Hypothyroidism; Lingual T | 2017 |
[Problems typical for patients with hypopituitarism - a case presentation].
Topics: Bone Density; Child; Estrogens; Female; Follow-Up Studies; Growth Disorders; Growth Hormone; Humans; | 2008 |
Two cases describing the effects of hypothyroidism on puberty and growth.
Topics: Child; Female; Growth Disorders; Hormone Replacement Therapy; Humans; Hypothyroidism; Puberty, Preco | 2008 |
Thyroid autoimmunity in children with coeliac disease: a prospective survey.
Topics: Adolescent; Autoimmune Diseases; Celiac Disease; Child; Child, Preschool; Diet, Gluten-Free; Female; | 2011 |
Diagnostic workup of the short child.
Topics: Blood Chemical Analysis; Body Height; Child; Child, Preschool; Dwarfism, Pituitary; Female; Growth D | 2011 |
Short stature in a patient with familial glucocorticoid deficiency.
Topics: Adrenal Insufficiency; Body Height; Child; Child Development; Congenital Hypothyroidism; Family Heal | 2011 |
A 5-year-old boy with atrophic autoimmune thyroiditis caused by thyroid-stimulation blocking antibodies.
Topics: Antibodies, Blocking; Child Development; Child, Preschool; Growth Disorders; Hormone Replacement The | 2011 |
A mutation in the thyroid hormone receptor alpha gene.
Topics: Child; Codon, Nonsense; Female; Growth Disorders; Heterozygote; Humans; Hypothyroidism; Models, Mole | 2012 |
Mice deficient in dual oxidase maturation factors are severely hypothyroid.
Topics: Animals; Disease Models, Animal; Dual Oxidases; Female; Gene Knockout Techniques; Growth Disorders; | 2012 |
Does clinical management impact height potential in children with severe acquired hypothyroidism?
Topics: Adolescent; Body Height; Bone Development; Child; Child Development; Drug Therapy, Combination; Fema | 2011 |
Delayed development of specific thyroid hormone-regulated events in transthyretin null mice.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Growth and Development; Growth Disorders; Mice; Mic | 2013 |
Visual diagnosis: two infants who have coarse facial features and growth and developmental delay.
Topics: Congenital Hypothyroidism; Developmental Disabilities; Facies; Growth Disorders; Humans; Hypothyroid | 2003 |
[Relationship between serum thyroid hormone and GH-IGF axis, growth failure in nephrotic rats].
Topics: Animals; Doxorubicin; Growth Disorders; Male; Nephrotic Syndrome; Random Allocation; Rats; Rats, Spr | 2001 |
Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism.
Topics: Aging; Animals; Brain; Congenital Hypothyroidism; Disease Models, Animal; DNA-Binding Proteins; Fema | 2003 |
[Hypothyroidism in children. 82 cases].
Topics: Child; Developmental Disabilities; Female; Growth Disorders; Humans; Hypothyroidism; Infant, Newborn | 2002 |
Clinical and hormonal characteristics of central hypothyroidism at diagnosis and during follow-up in adult patients.
Topics: Adult; Age of Onset; Aged; Fatigue; Female; Follow-Up Studies; Growth Disorders; Headache; Human Gro | 2004 |
Ovarian cyst in juvenile hypothyroidism.
Topics: Child; Female; Growth Disorders; Humans; Hypothyroidism; Ovarian Cysts; Puberty, Precocious; Thyroxi | 2005 |
Compound heterozygous and homozygous mutations of the TSHbeta gene as a cause of congenital central hypothyroidism in Europe.
Topics: Child; Child, Preschool; Congenital Hypothyroidism; Europe; Family Health; Female; Genotype; Germ-Li | 2004 |
Thyroid hormone, but not parathyroid hormone, partially restores glucocorticoid-induced growth retardation.
Topics: Animals; Dexamethasone; Female; Glucocorticoids; Growth Disorders; Mice; Parathyroid Hormone; Thyrox | 2005 |
Transient hypothyroxinemia in preterm infants: the role of cord sera thyroid hormone levels adjusted for prenatal and intrapartum factors.
Topics: Chemistry, Clinical; Cohort Studies; Fetal Blood; Gestational Age; Growth Disorders; Humans; Hypothy | 2005 |
Use of growth hormone and gonadotropin releasing hormone agonist in addition to L-thyroxine to attain normal adult height in two patients with severe Hashimoto's thyroiditis.
Topics: Adolescent; Body Height; Body Weight; Drug Therapy, Combination; Female; Gonadotropin-Releasing Horm | 2005 |
Severe hypothyroidism due to atrophic thyroiditis from second year of life influenced developmental outcome.
Topics: Atrophy; Biopsy, Needle; Child, Preschool; Developmental Disabilities; Dose-Response Relationship, D | 2005 |
Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patients.
Topics: Adolescent; Adult; Aged; Chi-Square Distribution; Female; Growth Disorders; Hormone Replacement Ther | 2007 |
Association of a nicotinic receptor mutation with reduced height and blunted physostigmine-stimulated growth hormone release.
Topics: Adolescent; Adult; Aged; Body Height; Body Mass Index; Cholinesterase Inhibitors; Female; Follicle S | 2008 |
Endocrine dysfunction in children with Crohn's disease.
Topics: Adolescent; Blood Sedimentation; Crohn Disease; Endocrine Glands; Female; Folic Acid; Gonadotropin-R | 1984 |
Evidence for dopaminergic stimulation of growth velocity in some hypopituitary children.
Topics: Age Determination by Skeleton; Bromocriptine; Child; Child, Preschool; Estradiol; Female; Follicle S | 1984 |
Familial growth retardation with isolated thyroid-stimulating hormone deficiency.
Topics: Adolescent; Child; Growth Disorders; Humans; Male; Thyrotropin; Thyrotropin-Releasing Hormone; Thyro | 1984 |
A blunted growth curve in an adolescent girl.
Topics: Adolescent; Diagnosis, Differential; Female; Growth Disorders; Humans; Hypothyroidism; Thyroiditis, | 1982 |
Clinical recognition of juvenile hypothyroidism in the early stage.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Goiter; Growth Disorders; Humans; Hypo | 1980 |
Defective clonidine-induced growth hormone secretion and normal thyroid and adrenal functions in prepubertal children with chronic renal insufficiency (CRF).
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Anthropometry; Child; Child, Preschool; Clo | 1995 |
In vivo responsiveness of thyroid glands to TSH in normal and novel 'growth-retarded' mice: transient elevation in normal mice and impairment in 'growth-retarded' mice.
Topics: Aging; Animals; Growth Disorders; Male; Mice; Mice, Mutant Strains; Thyroid Gland; Thyrotropin; Thyr | 1995 |
[Growth in children with impairment of thyroid gland function].
Topics: Congenital Hypothyroidism; Growth Disorders; Humans; Hypothyroidism; Infant; Infant, Newborn; Somato | 1995 |
Plasma levels of insulin-like growth factor-I are reduced at one week of age in monosodium L-glutamate-treated mice.
Topics: Age Factors; Animals; Animals, Newborn; Growth Disorders; Hypothalamus; Insulin; Insulin-Like Growth | 1993 |
Diagnostic evaluation of short children with height 3 SD or more below the mean.
Topics: Body Height; Child; Child, Preschool; Female; Fetal Growth Retardation; Follow-Up Studies; Growth Di | 1994 |
Attainment of normal height in severe juvenile hypothyroidism.
Topics: Adolescent; Age Determination by Skeleton; Body Height; Female; Gonadotropin-Releasing Hormone; Grow | 1994 |
Growth in early treated congenital hypothyroidism.
Topics: Birth Weight; Body Height; Body Mass Index; Body Weight; Cephalometry; Child, Preschool; Congenital | 1994 |
Developmental plasticity of the rat olfactory receptor sheet as shown by complete recovery of surface area and cell number from extensive early hypothyroid growth retardation.
Topics: Animals; Animals, Newborn; Cell Count; Epithelium; Growth Disorders; Hypothyroidism; Male; Neuronal | 1993 |
Auxologic data and hormonal profile in long-term survivors of childhood acute lymphoid leukemia.
Topics: Adolescent; Body Height; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Foll | 1993 |
Catch-up growth after prolonged hypothyroidism.
Topics: Adolescent; Child; Congenital Hypothyroidism; Female; Growth; Growth Disorders; Humans; Hypothyroidi | 1996 |
Growth parameters, growth hormone (GH) response to clonidine and circulating insulin-like growth factor-I (IGF-I), free thyroxine (FT4) and cortisol concentrations in relation to glycaemic control in children with insulin-dependent diabetes mellitus.
Topics: Body Mass Index; Case-Control Studies; Child; Child, Preschool; Clonidine; Diabetes Mellitus, Type 1 | 1996 |
Thyroid functions in mild and severe forms of sickle cell anemia.
Topics: Adolescent; Age Determination by Skeleton; Anemia, Sickle Cell; Body Height; Body Weight; Case-Contr | 1996 |
Defective response of body height to growth hormone treatment in resistance to thyroid hormone with short stature.
Topics: Adolescent; Body Height; Drug Resistance; Female; Growth Disorders; Human Growth Hormone; Humans; In | 1996 |
Linear growth in early treated children with congenital hypothyroidism.
Topics: Age Factors; Body Height; Case-Control Studies; Child; Child, Preschool; Congenital Hypothyroidism; | 1997 |
Effect of growth hormone on fatty liver in panhypopituitarism.
Topics: Adolescent; Anti-Inflammatory Agents; Fatty Liver; Growth Disorders; Growth Hormone; Humans; Hydroco | 1997 |
Impaired reproductive function in women treated for growth hormone deficiency during childhood.
Topics: Adult; Child; Female; Fertilization in Vitro; Follow-Up Studies; Growth Disorders; Growth Hormone; H | 1997 |
Dental maturity in children of short stature, with or without growth hormone deficiency.
Topics: Age Determination by Skeleton; Age Determination by Teeth; Aging; Alkaline Phosphatase; Body Height; | 1997 |
[The effectiveness of recombinant growth hormone in height deficiency due to intrauterine growth retardation].
Topics: Age Determination by Skeleton; Body Constitution; Body Weight; Child; Child, Preschool; Female; Feta | 1999 |
Growth hormone treatment in short children with beta-thalassemia major.
Topics: beta-Thalassemia; Body Height; Child; Growth Disorders; Growth Hormone; Humans; Insulin; Insulin-Lik | 2000 |
The combined pituitary function test in children: an evaluation of the clinical usefulness of TRH and LHRH stimulation tests through a retrospective analysis of one hundred and twenty six cases.
Topics: Adolescent; Area Under Curve; Child; Child, Preschool; Evaluation Studies as Topic; Female; Gonadotr | 2000 |
Thyroid function in thalassaemia major.
Topics: Adolescent; Adult; Age Determination by Skeleton; beta-Thalassemia; Body Height; Child; Child, Presc | 1999 |
Changes in serum thyroid hormones levels and their mechanisms during long-term growth hormone (GH) replacement therapy in GH deficient children.
Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Growth Disorders; Growth Hormone; Hormone Repla | 2000 |
Growth hormone deficiency caused by pituitary stalk interruption in Fanconi's anemia.
Topics: Body Height; Body Weight; Child; Child, Preschool; Fanconi Anemia; Female; Follicle Stimulating Horm | 2001 |
Growth parameters and endocrine function in relation to echocardiographic parameters in children with ventricular septal defect without heart failure.
Topics: Body Mass Index; Case-Control Studies; Child; Child, Preschool; Clonidine; Egypt; Female; Growth Dis | 2001 |
Kocher Debre Semelaigne syndrome: regression of pesudohypertrophy of muscles on thyroxine.
Topics: Child; Growth Disorders; Humans; Hypertrophy; Hypothyroidism; Intellectual Disability; Male; Muscles | 2002 |
Children with irreversible brain damage associated with hypothyroidism and multiple intracranial calcifications.
Topics: Basal Ganglia Diseases; Calcinosis; Cerebral Palsy; Child, Preschool; Female; Growth Disorders; Huma | 2002 |
Short stature in an adolescent due to spondyloepiphysial dysplasia tarda.
Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Follicle Stimulating Hormone; Growth | 1975 |
Medical Research Council of Canada therapeutic trial of human growth hormone: first 5 years of therapy.
Topics: Adolescent; Age Determination by Skeleton; Antibodies; Body Height; Brain Neoplasms; Canada; Child; | 1975 |
Peripheral resistance to thyroxine: a cause of short stature in a boy without goitre.
Topics: Adolescent; Age Determination by Skeleton; Body Weight; Child; Drug Resistance; Growth Disorders; Hu | 1975 |
Effect of oral thyrotrophin-releasing hormone on serum thyroxine in growth hormone deficient and normal children.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Child; Child, Preschool; Diabetes Insipidus; Fema | 1975 |
Primary hypothyroidism. Differentiation from primary hypopituitarism.
Topics: Adolescent; Age Determination by Skeleton; Body Height; Body Weight; Child; Diabetes Mellitus, Type | 1975 |
Growth retardation, skeletal maturation and thyroid function in children with homozygous beta-thalassaemia.
Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Female; Growth Diso | 1978 |
Posttraumatic hypothalamo-pituitary insufficiency. Diagnostic and therapeutic problems in a prepubertal child.
Topics: Adrenal Glands; Child; Craniocerebral Trauma; Growth Disorders; Growth Hormone; Humans; Hydrocortiso | 1977 |
The effect of hypothyroidism on growth, serum growth hormone, the growth hormone-dependent somatomedin, insulin-like growth factor, and its carrier protein in rats.
Topics: Aging; Animals; Body Weight; Carrier Proteins; Female; Growth Disorders; Growth Hormone; Hypothyroid | 1979 |
Serum cholesterol and triglycerides in children with growth hormone deficiency.
Topics: Adolescent; Adult; Body Height; Child; Cholesterol; Female; Growth Disorders; Growth Hormone; Humans | 1979 |
Familial hypopituitarism with large sella turcica.
Topics: Adolescent; Adult; Child; Female; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Hypothy | 1978 |
[Long bone growth changes in thymectomized rats in the pre-puberal stage (author's transl)].
Topics: Age Factors; Animals; Body Weight; Bone Development; Female; Femur; Growth Disorders; Hypothalamus; | 1978 |
[Thyroid involvement in cystinosis].
Topics: Adolescent; Child; Child, Preschool; Cholesterol; Cystinosis; Female; Follow-Up Studies; Growth Diso | 1978 |
Anemia and growth failure.
Topics: Anemia; Child; Female; Growth Disorders; Humans; Infant, Newborn; Myxedema; Pregnancy; Pregnancy Com | 1976 |
Growth hormone excess and sexual precocity in polyostotic fibrous dysplasia (McCune-Albright syndrome): evidence for abnormal hypothalamic function.
Topics: Blood Glucose; Child, Preschool; Estradiol; Fibrous Dysplasia of Bone; Fibrous Dysplasia, Polyostoti | 1975 |
[Treatment of pituitary growth retardation. Own experience with 32 patients (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Cortisone; Estrogens; Female; Growth Disorders; Growth Hormone; | 1975 |
Familial occurrence of growth hormone deficiency and primary hypothyroidism.
Topics: Adolescent; Child; DNA; Genetic Testing; Growth Disorders; Humans; Hypothyroidism; Male; Pedigree; T | 1992 |
Hyperthyroidism accelerates growth in Turner's syndrome.
Topics: Child; Female; Graves Disease; Growth Disorders; Humans; Methimazole; Propranolol; Puberty; Thyroid | 1992 |
Nocturnal thyrotropin surge in growth hormone-deficient children.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Growth Disorders; Growth Hormone; Humans; Hypoth | 1992 |
Growth prognosis and growth after menarche in primary hypothyroidism.
Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Female; Growth Diso | 1991 |
Endocrine characteristics of a miniature condition in Brahman cattle: circulating concentrations of some growth-related hormones.
Topics: Animals; Cattle; Cattle Diseases; Female; Growth Disorders; Growth Hormone; Insulin; Insulin-Like Gr | 1991 |
A preliminary report on the role of somatostatin analogue (SMS 201-995) in the management of children with tall stature.
Topics: Adolescent; Blood Glucose; Body Height; Child; Drug Administration Schedule; Female; Growth Disorder | 1990 |
[Growth catch-up in the case of congenital hypothyroidism after delayed treatment--a case report].
Topics: Adolescent; Body Height; Bone Development; Congenital Hypothyroidism; Growth Disorders; Humans; Hypo | 1990 |
Dental and skeletal changes in juvenile hypothyroidism following treatment: case report.
Topics: Body Height; Child; Growth Disorders; Humans; Hypothyroidism; Male; Thyroxine; Tooth Eruption; Tooth | 1990 |
Delayed growth in two German shepherd dog littermates with normal serum concentrations of growth hormone, thyroxine, and cortisol.
Topics: Adrenal Cortex; Animals; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Growth Disorders; Growth H | 1990 |
[Growth and bone maturity during congenital hypothyroidism screened in the neonatal period. Apropos of 82 cases].
Topics: Body Height; Bone Diseases, Developmental; Child; Child, Preschool; Congenital Hypothyroidism; Femal | 1989 |
Euthyroid hypothyrotropinemia in children of short stature.
Topics: Body Weight; Child; Fetal Growth Retardation; Growth Disorders; Humans; Male; Radioimmunoassay; Stan | 1989 |
Growth hormone treatment and circulating thyroxine.
Topics: Child; Growth Disorders; Growth Hormone; Human Growth Hormone; Humans; Recombinant Proteins; Somatos | 1986 |
Endogenous dopaminergic dysfunction: a novel form of human growth hormone deficiency and short stature.
Topics: Bromocriptine; Child; Child, Preschool; Dopamine; Estradiol; Female; Follicle Stimulating Hormone; G | 1986 |
Factors attenuating growth promoting effect of growth hormone therapy for Turner's syndrome.
Topics: Adolescent; Child; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Glycated Hemoglobin | 1988 |
Primary hypothyroidism presenting as growth delay and pituitary enlargement.
Topics: Child; Growth Disorders; Humans; Hyperplasia; Hypothyroidism; Male; Pituitary Gland; Thyroxine; Tomo | 1988 |
Growth impairment caused by dietary nitrate intake regulated via hypothyroidism and decreased somatomedin.
Topics: Animals; Feeding Behavior; Growth Disorders; Hypothyroidism; Iodine; Nitrates; Somatomedins; Swine; | 1987 |
[Organ dysfunctions caused by cancer therapy in children].
Topics: Antineoplastic Agents; Bone Development; Child; Child, Preschool; Cyclophosphamide; Female; Growth D | 1985 |
Thyroid function in human pregnancy. 8. Retardation of progeny aged 7 years; relationships to maternal age and maternal thyroid function.
Topics: Adolescent; Adult; Child; Child Development; Child, Preschool; Female; Gestational Age; Growth Disor | 1971 |
Turner syndrome with partial deletion of the X chromosome long arm.
Topics: Adolescent; Amenorrhea; Dermatoglyphics; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follicle | 1973 |
Abnormal height in children.
Topics: Adrenocorticotropic Hormone; Anabolic Agents; Body Height; Child; Estrogens; Growth; Growth Disorder | 1969 |
Adrenocortical and thyroid function in the deprivation syndrome. Comparison with growth failure due to undernutrition, congenital heart disease, or prenatal influences.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Basal Metabolism; Body Heigh | 1970 |
Failure of catch-up growth after Cushing's syndrome in childhood.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adrenocorticotropic Hormone; | 1972 |
[T3-thyrotoxicosis in a 3-year-old girl (author's transl)].
Topics: Age Determination by Skeleton; Bone Development; Child, Preschool; Diarrhea; Exophthalmos; Female; G | 1974 |
Serum gonadotropins in hypothyroid girls with and without sexual precocity.
Topics: Antibodies; Binding, Competitive; Blood Urea Nitrogen; Female; Follicle Stimulating Hormone; Growth | 1974 |
Inhibition of thyrotropin releasing hormone-mediated secretion of thyrotropin by human growth hormone.
Topics: Adolescent; Adult; Child; Female; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Male; R | 1973 |
The significance of intermediate plasma growth hormone levels in growth-retarded children.
Topics: Adolescent; Arginine; Blood Glucose; Child; Child, Preschool; Female; Glucose; Growth Disorders; Gro | 1972 |
Erythrocyte 2,3-diphosphoglycerate in adaptive red-cell-volume deficiency.
Topics: Adaptation, Physiological; Adolescent; Anemia; Animals; Child; Chromium Isotopes; Erythrocytes; Fema | 1971 |
The association of growth hormone deficiency and pituitary myxoedema.
Topics: Child; Deficiency Diseases; Female; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Hypot | 1970 |
Case report. Growth hormone response to insulin induced hypoglycemia in a boy with diabetes insipidus and short stature before and after treatment with vasopressin.
Topics: Adolescent; Diabetes Insipidus; Growth; Growth Disorders; Growth Hormone; Humans; Hypoglycemia; Insu | 1970 |
[ 132 -I uptake, the Thiopac test and percentage of free thyroxine in children with arrested somatic development].
Topics: Adolescent; Child; Child, Preschool; Dwarfism; Female; Growth; Growth Disorders; Humans; Hypothyroid | 1971 |