thyroxine has been researched along with Glioma in 17 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have determined the cellular concentration of thyroxine (T4) and triiodothyronine (T3) and the activities of two brain iodothyronine deiodinases, type II (5'-D2) and type III (5-D3), in two types of tissues --tumour (26) and non-tumour (5), derived either from human gliomas with various histological malignancies or from non-tumoural surrounding brain tissue." | 3.72 | The concentration of thyroid hormones and activities of iodothyronine deiodinases are altered in human brain gliomas. ( Bonicki, W; Czernicki, Z; Michalik, R; Nauman, P; Warzecha, A, 2004) |
| "The uptake of 3,5,3'-triiodothyronine (T3) and thyroxine (T4) was studied in human glioma cells (Hs 683) and compared with that in several other neural cell lines." | 3.68 | Thyroid hormone transport in a human glioma cell line. ( Goncalves, E; Lakshmanan, M; Pontecorvi, A; Robbins, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Iersel, L | 1 |
| Xu, J | 1 |
| Potter, BS | 1 |
| Conklin, HM | 1 |
| Zhang, H | 1 |
| Chemaitilly, W | 1 |
| van Santen, HM | 2 |
| Merchant, TE | 1 |
| Lin, HY | 3 |
| Sun, M | 2 |
| Tang, HY | 3 |
| Lin, C | 1 |
| Luidens, MK | 1 |
| Mousa, SA | 2 |
| Incerpi, S | 1 |
| Drusano, GL | 1 |
| Davis, FB | 4 |
| Davis, PJ | 4 |
| Hercbergs, A | 3 |
| Ciesielski, MJ | 1 |
| Leith, JT | 1 |
| Cho, JY | 1 |
| Shen, DH | 1 |
| Yang, W | 1 |
| Williams, B | 1 |
| Buckwalter, TL | 1 |
| La Perle, KM | 1 |
| Hinkle, G | 1 |
| Pozderac, R | 1 |
| Kloos, R | 1 |
| Nagaraja, HN | 1 |
| Barth, RF | 1 |
| Jhiang, SM | 1 |
| Wink, MR | 1 |
| Tamajusuku, AS | 1 |
| Braganhol, E | 1 |
| Casali, EA | 1 |
| Barreto-Chaves, ML | 1 |
| Sarkis, JJ | 1 |
| Battastini, AM | 1 |
| Nauman, P | 1 |
| Bonicki, W | 1 |
| Michalik, R | 1 |
| Warzecha, A | 1 |
| Czernicki, Z | 1 |
| Thonissen, NM | 1 |
| de Kraker, J | 1 |
| Vulsma, T | 1 |
| Shih, A | 2 |
| Keating, T | 2 |
| Lansing, L | 1 |
| Fenstermaker, RA | 1 |
| Mousa, A | 1 |
| Zamoner, A | 1 |
| Funchal, C | 1 |
| Jacques-Silva, MC | 1 |
| Gottfried, C | 1 |
| Barreto Silva, FR | 1 |
| Pessoa-Pureur, R | 1 |
| Wu, YH | 1 |
| Hammond, D | 1 |
| Elkouby, A | 2 |
| Ledig, M | 1 |
| Mandel, P | 2 |
| Farooqui, AA | 1 |
| Ogilvy-Stuart, AL | 1 |
| Shalet, SM | 1 |
| Gattamaneni, HR | 1 |
| Goncalves, E | 1 |
| Lakshmanan, M | 1 |
| Pontecorvi, A | 1 |
| Robbins, J | 1 |
| Walz, MA | 1 |
| Howlett, AC | 1 |
| Yusta, B | 2 |
| Ortiz-Caro, J | 2 |
| Pascual, A | 2 |
| Aranda, A | 2 |
| Montiel, F | 1 |
| Villa, A | 1 |
17 other studies available for thyroxine and Glioma
| Article | Year |
|---|---|
Clinical Importance of Free Thyroxine Concentration Decline After Radiotherapy for Pediatric and Adolescent Brain Tumors.
Topics: Adolescent; Aging; Body Height; Brain Neoplasms; Child; Child, Preschool; Cohort Studies; Disease Pr | 2019 |
L-Thyroxine vs. 3,5,3'-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase.
Topics: Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Glioma; Humans; Hypoxia-I | 2009 |
Radiosensitization of GL261 glioma cells by tetraiodothyroacetic acid (tetrac).
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glioma; Mice; Radiation Tolerance; | 2009 |
In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas.
Topics: Animals; Blotting, Western; Brain Neoplasms; Genetic Therapy; Genetic Vectors; Glioma; Humans; Immun | 2002 |
Thyroid hormone upregulates ecto-5'-nucleotidase/CD73 in C6 rat glioma cells.
Topics: 5'-Nucleotidase; Animals; Cell Line, Tumor; Dactinomycin; Dose-Response Relationship, Drug; Glioma; | 2003 |
The concentration of thyroid hormones and activities of iodothyronine deiodinases are altered in human brain gliomas.
Topics: Adult; Aged; Analysis of Variance; Brain Neoplasms; Female; Glioma; Humans; Iodide Peroxidase; Male; | 2004 |
Changes in thyroid hormone state in children receiving chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 2005 |
Acting via a cell surface receptor, thyroid hormone is a growth factor for glioma cells.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Glioma; Integrin alphaVbeta3; M | 2006 |
Thyroid hormones reorganize the cytoskeleton of glial cells through Gfap phosphorylation and Rhoa-dependent mechanisms.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cytoskeleton; Glial Fibrillar | 2007 |
Resveratrol is pro-apoptotic and thyroid hormone is anti-apoptotic in glioma cells: both actions are integrin and ERK mediated.
Topics: Apoptosis; Brain Neoplasms; Cyclooxygenase 2; Enzyme Activation; Extracellular Signal-Regulated MAP | 2008 |
Effect of hydrocortisone and thyroxine on ATPase activities of neuronal and glial cell lines in culture.
Topics: Adenosine Triphosphatases; Animals; Astrocytes; Ca(2+) Mg(2+)-ATPase; Cell Line; Cricetinae; Glioma; | 1982 |
Effect of hydrocortisone and thyroxine on arylsulphatases A and B of cultured cells of neuronal and glial origin.
Topics: Animals; Arylsulfatases; Cells, Cultured; Cricetinae; Galactosidases; Glioma; Hydrocortisone; Kineti | 1977 |
Thyroid function after treatment of brain tumors in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine | 1991 |
Thyroid hormone transport in a human glioma cell line.
Topics: Aminoisobutyric Acids; Antimycin A; Binding, Competitive; Biological Transport; Cadaverine; Cell Mem | 1990 |
Thyroid effects on adenosine 3',5'-monophosphate levels and adenylate cyclase in cultured neuroblastoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cell Line; Colforsin; Cyclic AMP; Glioma; Guan | 1987 |
Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate.
Topics: Animals; Antimycin A; Azides; Butyrates; Cell Membrane Permeability; Cyanides; Glioma; Rats; Sodium | 1988 |
Identification and characterization of L-triiodothyronine receptors in cells of glial and neuronal origin.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Glioma; Kinetics; Mice; Neuroblastoma; Ne | 1986 |