thyroxine has been researched along with Gestational Hypertension in 17 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The incidences of preterm birth, abortion, postpartum hemorrhage, and low birth weight infants in the pregnant women treated with levothyroxine sodium were lower than those in the control group [odds ratio (OR) =0." | 9.22 | Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism. ( Chen, Y; Geng, X; Li, N; Ma, J; Sun, C; Wang, W; Wu, W, 2022) |
| "To investigate the association between hypothyroxinemia and the risk of preeclampsia-eclampsia and gestational hypertension." | 8.02 | Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension. ( Du, Q; Duan, T; Huang, S; Li, G; Liu, X; Liu, Y; Su, X, 2021) |
| "This was a secondary analysis of two parallel multicenter clinical trials of thyroxine therapy for subclinical hypothyroid disorders in pregnancy." | 5.51 | Association between Hypertensive Disorders of Pregnancy and Long-Term Neurodevelopmental Outcomes in the Offspring. ( Caritis, SN; Casey, BM; Costantine, MM; Mele, L; Mercer, BM; Palatnik, A; Reddy, UM; Rouse, DJ; Saade, GR; Sibai, B; Sorokin, Y; Thorp, JM; Tita, ATN; Tolosa, JE; Varner, MW; Wapner, RJ, 2022) |
| " The incidences of preterm birth, abortion, postpartum hemorrhage, and low birth weight infants in the pregnant women treated with levothyroxine sodium were lower than those in the control group [odds ratio (OR) =0." | 5.22 | Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism. ( Chen, Y; Geng, X; Li, N; Ma, J; Sun, C; Wang, W; Wu, W, 2022) |
| "To investigate the association between hypothyroxinemia and the risk of preeclampsia-eclampsia and gestational hypertension." | 4.02 | Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension. ( Du, Q; Duan, T; Huang, S; Li, G; Liu, X; Liu, Y; Su, X, 2021) |
| " The patient had an elevated thyroid-stimulating hormone with normal free thyroxine (T4) levels and was positive for thyroid peroxidase antibodies resulting in a diagnosis of subclinical hypothyroidism." | 3.83 | Subclinical hypothyroidism causing hypertension in pregnancy. ( Dhanoo, A; Ramtahal, R, 2016) |
| " Serum levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), TSH-receptor antibody (TRAb), the duration of hyperthyroidism in pregnancy, doses of antithyroid medication, and the duration of maternal antithyroid medication throughout pregnancy were compared." | 3.80 | Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease. ( Ebina, Y; Morioka, I; Tairaku, S; Tanimura, K; Uenaka, M; Yamada, H, 2014) |
| "These results quantify the risks of gestational hypertension or pre-eclampsia in women with thyroid function test abnormalities, adding to the total body of evidence on the risk of adverse maternal and fetal outcomes of thyroid dysfunction during pregnancy." | 2.82 | Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. ( Alexander, EK; Auvinen, J; Bassols, J; Bliddal, S; Boucai, L; Brito, JP; Brown, SJ; Carty, DM; Chaker, L; Chatzi, L; Chen, L; Delles, C; Derakhshan, A; Feldt-Rasmussen, U; Grineva, EN; Guxens, M; Hisada, A; Itoh, S; Jiménez-Zabala, A; Kishi, R; Korevaar, TIM; López-Bermejo, A; Lopez-Espinosa, MJ; Lu, X; Männistö, T; Maraka, S; Mosso, L; Nelson, SM; Oken, E; Pearce, EN; Peeters, RP; Pop, VJM; Popova, PV; Prokop, LJ; Riaño-Galan, I; Rodriguez-Gutierrez, R; Roeters van Lennep, JE; Shilova, E; Singh Ospina, N; Sunyer, J; Suvanto, E; Taylor, P; Toloza, FJK; Vrijkotte, TGM; Walsh, JP; Yoshinaga, J, 2022) |
| "There was a 73% less chance of gestational hypertension for thyroid autoimmune groups." | 1.62 | Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4). ( Islam, N; Kiran, Z; Sheikh, A, 2021) |
| "Maternal hypothyroidism is associated with several pregnancy and perinatal complications, but consistent LT4 use may reduce many of the risks." | 1.51 | Pregnancy and Perinatal Outcome Among Hypothyroid Mothers: A Population-Based Cohort Study. ( Gissler, M; Hartikainen, AL; Lahesmaa-Korpinen, AM; Männistö, T; Suvanto, E; Turunen, S; Vääräsmäki, M, 2019) |
| "Perinatal outcomes of women with treated overt hypothyroidism were similar to women with euthyroidism." | 1.42 | An analysis of population-based prenatal screening for overt hypothyroidism. ( Bryant, SN; Casey, BM; Cunningham, FG; McIntire, DD; Nelson, DB, 2015) |
| "The incidence of the pregnancy complications in the TPOAb (+) treated group was higher than those in the control group, but the differences were not statistically significant (P > 0." | 1.42 | [Effect of the treatment acceptance on the perinatal outcomes in women with subclinical hypothyroidism, positive thyroid gland peroxidase antibody in early pregnancy]. ( Ding, S; Guo, H; Tao, B; Yang, J; Zhang, X, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 8 (47.06) | 2.80 |
| Authors | Studies |
|---|---|
| Palatnik, A | 1 |
| Mele, L | 1 |
| Casey, BM | 3 |
| Varner, MW | 1 |
| Sorokin, Y | 1 |
| Reddy, UM | 1 |
| Wapner, RJ | 1 |
| Thorp, JM | 1 |
| Saade, GR | 1 |
| Tita, ATN | 1 |
| Rouse, DJ | 1 |
| Sibai, B | 1 |
| Costantine, MM | 1 |
| Mercer, BM | 1 |
| Tolosa, JE | 1 |
| Caritis, SN | 1 |
| Su, X | 1 |
| Liu, Y | 2 |
| Li, G | 1 |
| Liu, X | 1 |
| Huang, S | 1 |
| Duan, T | 1 |
| Du, Q | 1 |
| Di Girolamo, R | 1 |
| Liberati, M | 1 |
| Silvi, C | 1 |
| D'Antonio, F | 1 |
| Toloza, FJK | 1 |
| Derakhshan, A | 1 |
| Männistö, T | 2 |
| Bliddal, S | 1 |
| Popova, PV | 1 |
| Carty, DM | 1 |
| Chen, L | 1 |
| Taylor, P | 1 |
| Mosso, L | 1 |
| Oken, E | 1 |
| Suvanto, E | 2 |
| Itoh, S | 1 |
| Kishi, R | 1 |
| Bassols, J | 1 |
| Auvinen, J | 1 |
| López-Bermejo, A | 1 |
| Brown, SJ | 1 |
| Boucai, L | 1 |
| Hisada, A | 1 |
| Yoshinaga, J | 1 |
| Shilova, E | 1 |
| Grineva, EN | 1 |
| Vrijkotte, TGM | 1 |
| Sunyer, J | 1 |
| Jiménez-Zabala, A | 1 |
| Riaño-Galan, I | 1 |
| Lopez-Espinosa, MJ | 1 |
| Prokop, LJ | 1 |
| Singh Ospina, N | 1 |
| Brito, JP | 1 |
| Rodriguez-Gutierrez, R | 1 |
| Alexander, EK | 1 |
| Chaker, L | 1 |
| Pearce, EN | 1 |
| Peeters, RP | 1 |
| Feldt-Rasmussen, U | 1 |
| Guxens, M | 1 |
| Chatzi, L | 1 |
| Delles, C | 1 |
| Roeters van Lennep, JE | 1 |
| Pop, VJM | 1 |
| Lu, X | 1 |
| Walsh, JP | 1 |
| Nelson, SM | 1 |
| Korevaar, TIM | 1 |
| Maraka, S | 1 |
| Han, Y | 1 |
| Wang, J | 1 |
| Wang, X | 1 |
| Ouyang, L | 1 |
| Li, Y | 1 |
| Geng, X | 1 |
| Chen, Y | 1 |
| Wang, W | 1 |
| Ma, J | 1 |
| Wu, W | 1 |
| Li, N | 1 |
| Sun, C | 1 |
| Aryee, NA | 1 |
| Adu-Bonsaffoh, K | 1 |
| Arko-Boham, B | 1 |
| Quaye, O | 1 |
| Asazu, H | 1 |
| Tagoe, E | 1 |
| Gao, B | 1 |
| Zeng, X | 1 |
| Yang, J | 2 |
| Zhang, L | 1 |
| Xu, G | 1 |
| Jia, R | 1 |
| Xu, Z | 1 |
| Kiran, Z | 1 |
| Sheikh, A | 1 |
| Islam, N | 1 |
| Turunen, S | 1 |
| Vääräsmäki, M | 1 |
| Hartikainen, AL | 1 |
| Lahesmaa-Korpinen, AM | 1 |
| Gissler, M | 1 |
| Uenaka, M | 1 |
| Tanimura, K | 1 |
| Tairaku, S | 1 |
| Morioka, I | 1 |
| Ebina, Y | 1 |
| Yamada, H | 1 |
| Bryant, SN | 1 |
| Nelson, DB | 1 |
| McIntire, DD | 2 |
| Cunningham, FG | 2 |
| Guo, H | 1 |
| Ding, S | 1 |
| Tao, B | 1 |
| Zhang, X | 1 |
| Kattah, A | 1 |
| Garovic, VD | 1 |
| Ramtahal, R | 1 |
| Dhanoo, A | 1 |
| Wilson, KL | 1 |
| Halvorson, LM | 1 |
| Buimer, M | 1 |
| van Wassenaer, AG | 1 |
| Ganzevoort, W | 1 |
| Wolf, H | 1 |
| Bleker, OP | 1 |
| Kok, JH | 1 |
4 reviews available for thyroxine and Gestational Hypertension
| Article | Year |
|---|---|
Levothyroxine Supplementation in Euthyroid Pregnant Women With Positive Autoantibodies: A Systematic Review and Meta-Analysis.
Topics: Abortion, Spontaneous; Abruptio Placentae; Autoantibodies; Dietary Supplements; Female; Humans; Hype | 2022 |
Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis.
Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hyperthyroidism; Hypothyroidism; Male; Pre-Eclampsi | 2022 |
Relationship Between Subclinical Hypothyroidism in Pregnancy and Hypertensive Disorder of Pregnancy: A Systematic Review and Meta-Analysis.
Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pregnancy; Pregnancy Complications; | 2022 |
Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism.
Topics: Abortion, Spontaneous; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Infant, Newb | 2022 |
1 trial available for thyroxine and Gestational Hypertension
| Article | Year |
|---|---|
Association between Hypertensive Disorders of Pregnancy and Long-Term Neurodevelopmental Outcomes in the Offspring.
Topics: Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Language Development Disorders; Pr | 2022 |
12 other studies available for thyroxine and Gestational Hypertension
| Article | Year |
|---|---|
Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension.
Topics: Adult; China; Cohort Studies; Eclampsia; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroi | 2021 |
Thyroid hormone profile in preeclampsia patients: a case control study.
Topics: Case-Control Studies; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pre-Eclampsia | 2023 |
Association between thyroid-stimulating hormone and maternal hemodynamics in hypertensive disorders of pregnancy: an observational study.
Topics: Adult; Biomarkers; Birth Weight; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pregnan | 2019 |
Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4).
Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Apgar Score; Autoantibodies; Autoimmune Diseases; | 2021 |
Pregnancy and Perinatal Outcome Among Hypothyroid Mothers: A Population-Based Cohort Study.
Topics: Adult; Cesarean Section; Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Hyp | 2019 |
Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease.
Topics: Abortion, Spontaneous; Adult; Antithyroid Agents; Congenital Hypothyroidism; Female; Fetal Growth Re | 2014 |
An analysis of population-based prenatal screening for overt hypothyroidism.
Topics: Adolescent; Adult; Asymptomatic Diseases; Cohort Studies; Female; Humans; Hypertension, Pregnancy-In | 2015 |
[Effect of the treatment acceptance on the perinatal outcomes in women with subclinical hypothyroidism, positive thyroid gland peroxidase antibody in early pregnancy].
Topics: Abortion, Spontaneous; Autoantibodies; Case-Control Studies; Diabetes, Gestational; Female; Humans; | 2015 |
Subclinical hypothyroidism and gestational hypertension: causal or coincidence?
Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pregnancy; Thyrotropin; Thyroxine | 2016 |
Subclinical hypothyroidism causing hypertension in pregnancy.
Topics: Adult; Antihypertensive Agents; Autoantibodies; Diagnosis, Differential; Female; Humans; Hypertensio | 2016 |
Subclinical thyroid disease and the incidence of hypertension in pregnancy.
Topics: Adult; Analysis of Variance; Eclampsia; Female; Humans; Hypertension, Pregnancy-Induced; Hyperthyroi | 2012 |
Transient hypothyroxinemia in severe hypertensive disorders of pregnancy.
Topics: Adult; Autoimmunity; Cohort Studies; Female; Fetal Blood; Humans; Hypertension, Pregnancy-Induced; I | 2005 |