Page last updated: 2024-11-06

thyroxine and Gestational Hypertension

thyroxine has been researched along with Gestational Hypertension in 17 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
" The incidences of preterm birth, abortion, postpartum hemorrhage, and low birth weight infants in the pregnant women treated with levothyroxine sodium were lower than those in the control group [odds ratio (OR) =0."9.22Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism. ( Chen, Y; Geng, X; Li, N; Ma, J; Sun, C; Wang, W; Wu, W, 2022)
"To investigate the association between hypothyroxinemia and the risk of preeclampsia-eclampsia and gestational hypertension."8.02Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension. ( Du, Q; Duan, T; Huang, S; Li, G; Liu, X; Liu, Y; Su, X, 2021)
"This was a secondary analysis of two parallel multicenter clinical trials of thyroxine therapy for subclinical hypothyroid disorders in pregnancy."5.51Association between Hypertensive Disorders of Pregnancy and Long-Term Neurodevelopmental Outcomes in the Offspring. ( Caritis, SN; Casey, BM; Costantine, MM; Mele, L; Mercer, BM; Palatnik, A; Reddy, UM; Rouse, DJ; Saade, GR; Sibai, B; Sorokin, Y; Thorp, JM; Tita, ATN; Tolosa, JE; Varner, MW; Wapner, RJ, 2022)
" The incidences of preterm birth, abortion, postpartum hemorrhage, and low birth weight infants in the pregnant women treated with levothyroxine sodium were lower than those in the control group [odds ratio (OR) =0."5.22Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism. ( Chen, Y; Geng, X; Li, N; Ma, J; Sun, C; Wang, W; Wu, W, 2022)
"To investigate the association between hypothyroxinemia and the risk of preeclampsia-eclampsia and gestational hypertension."4.02Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension. ( Du, Q; Duan, T; Huang, S; Li, G; Liu, X; Liu, Y; Su, X, 2021)
" The patient had an elevated thyroid-stimulating hormone with normal free thyroxine (T4) levels and was positive for thyroid peroxidase antibodies resulting in a diagnosis of subclinical hypothyroidism."3.83Subclinical hypothyroidism causing hypertension in pregnancy. ( Dhanoo, A; Ramtahal, R, 2016)
" Serum levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), TSH-receptor antibody (TRAb), the duration of hyperthyroidism in pregnancy, doses of antithyroid medication, and the duration of maternal antithyroid medication throughout pregnancy were compared."3.80Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease. ( Ebina, Y; Morioka, I; Tairaku, S; Tanimura, K; Uenaka, M; Yamada, H, 2014)
"These results quantify the risks of gestational hypertension or pre-eclampsia in women with thyroid function test abnormalities, adding to the total body of evidence on the risk of adverse maternal and fetal outcomes of thyroid dysfunction during pregnancy."2.82Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. ( Alexander, EK; Auvinen, J; Bassols, J; Bliddal, S; Boucai, L; Brito, JP; Brown, SJ; Carty, DM; Chaker, L; Chatzi, L; Chen, L; Delles, C; Derakhshan, A; Feldt-Rasmussen, U; Grineva, EN; Guxens, M; Hisada, A; Itoh, S; Jiménez-Zabala, A; Kishi, R; Korevaar, TIM; López-Bermejo, A; Lopez-Espinosa, MJ; Lu, X; Männistö, T; Maraka, S; Mosso, L; Nelson, SM; Oken, E; Pearce, EN; Peeters, RP; Pop, VJM; Popova, PV; Prokop, LJ; Riaño-Galan, I; Rodriguez-Gutierrez, R; Roeters van Lennep, JE; Shilova, E; Singh Ospina, N; Sunyer, J; Suvanto, E; Taylor, P; Toloza, FJK; Vrijkotte, TGM; Walsh, JP; Yoshinaga, J, 2022)
"There was a 73% less chance of gestational hypertension for thyroid autoimmune groups."1.62Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4). ( Islam, N; Kiran, Z; Sheikh, A, 2021)
"Maternal hypothyroidism is associated with several pregnancy and perinatal complications, but consistent LT4 use may reduce many of the risks."1.51Pregnancy and Perinatal Outcome Among Hypothyroid Mothers: A Population-Based Cohort Study. ( Gissler, M; Hartikainen, AL; Lahesmaa-Korpinen, AM; Männistö, T; Suvanto, E; Turunen, S; Vääräsmäki, M, 2019)
"Perinatal outcomes of women with treated overt hypothyroidism were similar to women with euthyroidism."1.42An analysis of population-based prenatal screening for overt hypothyroidism. ( Bryant, SN; Casey, BM; Cunningham, FG; McIntire, DD; Nelson, DB, 2015)
"The incidence of the pregnancy complications in the TPOAb (+) treated group was higher than those in the control group, but the differences were not statistically significant (P > 0."1.42[Effect of the treatment acceptance on the perinatal outcomes in women with subclinical hypothyroidism, positive thyroid gland peroxidase antibody in early pregnancy]. ( Ding, S; Guo, H; Tao, B; Yang, J; Zhang, X, 2015)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's8 (47.06)24.3611
2020's8 (47.06)2.80

Authors

AuthorsStudies
Palatnik, A1
Mele, L1
Casey, BM3
Varner, MW1
Sorokin, Y1
Reddy, UM1
Wapner, RJ1
Thorp, JM1
Saade, GR1
Tita, ATN1
Rouse, DJ1
Sibai, B1
Costantine, MM1
Mercer, BM1
Tolosa, JE1
Caritis, SN1
Su, X1
Liu, Y2
Li, G1
Liu, X1
Huang, S1
Duan, T1
Du, Q1
Di Girolamo, R1
Liberati, M1
Silvi, C1
D'Antonio, F1
Toloza, FJK1
Derakhshan, A1
Männistö, T2
Bliddal, S1
Popova, PV1
Carty, DM1
Chen, L1
Taylor, P1
Mosso, L1
Oken, E1
Suvanto, E2
Itoh, S1
Kishi, R1
Bassols, J1
Auvinen, J1
López-Bermejo, A1
Brown, SJ1
Boucai, L1
Hisada, A1
Yoshinaga, J1
Shilova, E1
Grineva, EN1
Vrijkotte, TGM1
Sunyer, J1
Jiménez-Zabala, A1
Riaño-Galan, I1
Lopez-Espinosa, MJ1
Prokop, LJ1
Singh Ospina, N1
Brito, JP1
Rodriguez-Gutierrez, R1
Alexander, EK1
Chaker, L1
Pearce, EN1
Peeters, RP1
Feldt-Rasmussen, U1
Guxens, M1
Chatzi, L1
Delles, C1
Roeters van Lennep, JE1
Pop, VJM1
Lu, X1
Walsh, JP1
Nelson, SM1
Korevaar, TIM1
Maraka, S1
Han, Y1
Wang, J1
Wang, X1
Ouyang, L1
Li, Y1
Geng, X1
Chen, Y1
Wang, W1
Ma, J1
Wu, W1
Li, N1
Sun, C1
Aryee, NA1
Adu-Bonsaffoh, K1
Arko-Boham, B1
Quaye, O1
Asazu, H1
Tagoe, E1
Gao, B1
Zeng, X1
Yang, J2
Zhang, L1
Xu, G1
Jia, R1
Xu, Z1
Kiran, Z1
Sheikh, A1
Islam, N1
Turunen, S1
Vääräsmäki, M1
Hartikainen, AL1
Lahesmaa-Korpinen, AM1
Gissler, M1
Uenaka, M1
Tanimura, K1
Tairaku, S1
Morioka, I1
Ebina, Y1
Yamada, H1
Bryant, SN1
Nelson, DB1
McIntire, DD2
Cunningham, FG2
Guo, H1
Ding, S1
Tao, B1
Zhang, X1
Kattah, A1
Garovic, VD1
Ramtahal, R1
Dhanoo, A1
Wilson, KL1
Halvorson, LM1
Buimer, M1
van Wassenaer, AG1
Ganzevoort, W1
Wolf, H1
Bleker, OP1
Kok, JH1

Reviews

4 reviews available for thyroxine and Gestational Hypertension

ArticleYear
Levothyroxine Supplementation in Euthyroid Pregnant Women With Positive Autoantibodies: A Systematic Review and Meta-Analysis.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Abortion, Spontaneous; Abruptio Placentae; Autoantibodies; Dietary Supplements; Female; Humans; Hype

2022
Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis.
    The lancet. Diabetes & endocrinology, 2022, Volume: 10, Issue:4

    Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hyperthyroidism; Hypothyroidism; Male; Pre-Eclampsi

2022
Relationship Between Subclinical Hypothyroidism in Pregnancy and Hypertensive Disorder of Pregnancy: A Systematic Review and Meta-Analysis.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pregnancy; Pregnancy Complications;

2022
Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism.
    Annals of palliative medicine, 2022, Volume: 11, Issue:4

    Topics: Abortion, Spontaneous; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Infant, Newb

2022

Trials

1 trial available for thyroxine and Gestational Hypertension

ArticleYear
Association between Hypertensive Disorders of Pregnancy and Long-Term Neurodevelopmental Outcomes in the Offspring.
    American journal of perinatology, 2022, Volume: 39, Issue:9

    Topics: Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Language Development Disorders; Pr

2022

Other Studies

12 other studies available for thyroxine and Gestational Hypertension

ArticleYear
Associations of Hypothyroxinemia With Risk of Preeclampsia-Eclampsia and Gestational Hypertension.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; China; Cohort Studies; Eclampsia; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroi

2021
Thyroid hormone profile in preeclampsia patients: a case control study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2023, Volume: 39, Issue:1

    Topics: Case-Control Studies; Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pre-Eclampsia

2023
Association between thyroid-stimulating hormone and maternal hemodynamics in hypertensive disorders of pregnancy: an observational study.
    BMC pregnancy and childbirth, 2019, Nov-01, Volume: 19, Issue:1

    Topics: Adult; Biomarkers; Birth Weight; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pregnan

2019
Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4).
    BMC pregnancy and childbirth, 2021, Feb-15, Volume: 21, Issue:1

    Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Apgar Score; Autoantibodies; Autoimmune Diseases;

2021
Pregnancy and Perinatal Outcome Among Hypothyroid Mothers: A Population-Based Cohort Study.
    Thyroid : official journal of the American Thyroid Association, 2019, Volume: 29, Issue:1

    Topics: Adult; Cesarean Section; Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Hyp

2019
Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 177

    Topics: Abortion, Spontaneous; Adult; Antithyroid Agents; Congenital Hypothyroidism; Female; Fetal Growth Re

2014
An analysis of population-based prenatal screening for overt hypothyroidism.
    American journal of obstetrics and gynecology, 2015, Volume: 213, Issue:4

    Topics: Adolescent; Adult; Asymptomatic Diseases; Cohort Studies; Female; Humans; Hypertension, Pregnancy-In

2015
[Effect of the treatment acceptance on the perinatal outcomes in women with subclinical hypothyroidism, positive thyroid gland peroxidase antibody in early pregnancy].
    Zhonghua fu chan ke za zhi, 2015, Volume: 50, Issue:9

    Topics: Abortion, Spontaneous; Autoantibodies; Case-Control Studies; Diabetes, Gestational; Female; Humans;

2015
Subclinical hypothyroidism and gestational hypertension: causal or coincidence?
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:9

    Topics: Female; Humans; Hypertension, Pregnancy-Induced; Hypothyroidism; Pregnancy; Thyrotropin; Thyroxine

2016
Subclinical hypothyroidism causing hypertension in pregnancy.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:9

    Topics: Adult; Antihypertensive Agents; Autoantibodies; Diagnosis, Differential; Female; Humans; Hypertensio

2016
Subclinical thyroid disease and the incidence of hypertension in pregnancy.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:2 Pt 1

    Topics: Adult; Analysis of Variance; Eclampsia; Female; Humans; Hypertension, Pregnancy-Induced; Hyperthyroi

2012
Transient hypothyroxinemia in severe hypertensive disorders of pregnancy.
    Obstetrics and gynecology, 2005, Volume: 106, Issue:5 Pt 1

    Topics: Adult; Autoimmunity; Cohort Studies; Female; Fetal Blood; Humans; Hypertension, Pregnancy-Induced; I

2005