thyroxine has been researched along with Germinoblastoma in 25 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "EL-4 lymphoma cells transplanted to syngeneic C57BL/6J mice induced a biphasic decrease in inflammation and a bi-phasic increase in serum levels of corticosterone." | 7.67 | Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation. ( Besedovsky, H; del Rey, A; Normann, S; Schardt, M, 1988) |
| "The majority of thyroid cancer patients have normal levels of thyroid hormones; they are rarely hyperthyroid, with no obvious clinical features of thyrotoxicosis." | 5.37 | Primary thyroid lymphoma with elevated free thyroxine level. ( Din, SW; Ghazali, MZ; Mustafa, S; Yahaya, N, 2011) |
| "When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l." | 5.26 | Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976) |
| "In an attempt to reduce the incidence of hypothyroidism following irradiation of the neck, we administered oral L-thyroxine in doses sufficient to suppress serum TSH to 20 patients receiving radiation therapy for Hodgkin's disease or other lymphomas." | 5.05 | Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction. ( Bantle, JP; Lee, CK; Levitt, SH, 1985) |
| " The administration of thyroxine (T4) to dwarf mice increased body weight (BW) gain and the number of splenocytes/g BW." | 3.69 | The influence of thyroxine, growth hormone and prolactin alone and in combination on the production of prolactin-like activity by splenocytes from Snell dwarf mice. ( Gala, RR, 1995) |
| "EL-4 lymphoma cells transplanted to syngeneic C57BL/6J mice induced a biphasic decrease in inflammation and a bi-phasic increase in serum levels of corticosterone." | 3.67 | Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation. ( Besedovsky, H; del Rey, A; Normann, S; Schardt, M, 1988) |
| " A cytotoxic effect of this system on a line of mouse ascitic lymphoma cells (LSTRA) is demonstrated here using four different assay systems: 51Cr release, trypan blue exclusion, inhibition of glucose C-1 oxidation, and loss of oncogenicity for mice." | 3.65 | Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells. ( Clark, RA; Einstein, AB; Fefer, A; Klebanoff, SJ, 1975) |
| "Children with cancer were also evaluated after antineoplasic treatment (CAT, n = 17)." | 1.38 | Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment. ( Brito, CX; Guerra, RN; Liberio, SA; Lima, MV; Mendonça, C; Mouchrek-Filho, JC; Nascimento, FR; Oliveira-Junior, JJ; Paim, DB; Pereira, AL, 2012) |
| "The majority of thyroid cancer patients have normal levels of thyroid hormones; they are rarely hyperthyroid, with no obvious clinical features of thyrotoxicosis." | 1.37 | Primary thyroid lymphoma with elevated free thyroxine level. ( Din, SW; Ghazali, MZ; Mustafa, S; Yahaya, N, 2011) |
| "Whenever thyroid lymphoma is suspected, we recommend an ultrasound scan of the thyroid gland and fine needle aspiration biopsy as initial diagnostic procedures." | 1.29 | Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases. ( Ikeda, H; Katayama, S; Kuma, K; Matsuzuka, F; Miyauchi, A; Narabayashi, I; Sugawara, M, 1993) |
| "The mean thyroid dose for irradiated malignant lymphomas in the prospective and the retrospective group was 45 Gy and 43 Gy respectively." | 1.28 | Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis. ( Becker, W; Feyerabend, T; Kapp, B; Reiners, C; Richter, E, 1990) |
| "Patients with malignant lymphoma and acute myeloid leukemia showed a significant decrease in enzyme activity (p less than 0." | 1.27 | Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions. ( Saito, T, 1987) |
| "When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l." | 1.26 | Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976) |
| "The non-surgical treatment of thyroid cancer is outlined." | 1.25 | The non-surgical treatment of thyroid cancer. ( Halnan, KE, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (68.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frick, LR | 1 |
| Rapanelli, M | 1 |
| Bussmann, UA | 1 |
| Klecha, AJ | 1 |
| Arcos, ML | 1 |
| Genaro, AM | 1 |
| Cremaschi, GA | 1 |
| Yahaya, N | 1 |
| Din, SW | 1 |
| Ghazali, MZ | 1 |
| Mustafa, S | 1 |
| Guerra, RN | 1 |
| Oliveira-Junior, JJ | 1 |
| Mouchrek-Filho, JC | 1 |
| Liberio, SA | 1 |
| Lima, MV | 1 |
| Paim, DB | 1 |
| Brito, CX | 1 |
| Mendonça, C | 1 |
| Nascimento, FR | 1 |
| Pereira, AL | 1 |
| Pavelic, K | 1 |
| Pekic, B | 1 |
| Gabrilovac, J | 1 |
| Bratic-Mikes, V | 1 |
| Boranic, M | 1 |
| Simpson, WJ | 1 |
| Gemsenjäger, E | 1 |
| Girard, J | 1 |
| Gala, RR | 1 |
| Balmaceda, CM | 1 |
| Fetell, MR | 1 |
| Selman, JE | 1 |
| Seplowitz, AJ | 1 |
| Matsuzuka, F | 1 |
| Miyauchi, A | 1 |
| Katayama, S | 1 |
| Narabayashi, I | 1 |
| Ikeda, H | 1 |
| Kuma, K | 1 |
| Sugawara, M | 1 |
| Worm, AM | 2 |
| Brinckmeyer, LM | 2 |
| Nissen, NI | 2 |
| Doniach, D | 1 |
| Bottazzo, GF | 1 |
| Russell, RC | 1 |
| Halnan, KE | 1 |
| Carter, JN | 1 |
| Eastmen, CJ | 1 |
| Corcoran, JM | 1 |
| Lazarus, L | 1 |
| Clark, RA | 1 |
| Klebanoff, SJ | 1 |
| Einstein, AB | 1 |
| Fefer, A | 1 |
| Evered, DC | 1 |
| Feyerabend, T | 1 |
| Kapp, B | 1 |
| Richter, E | 1 |
| Becker, W | 1 |
| Reiners, C | 1 |
| Hershman, JM | 1 |
| Eriksen, E | 1 |
| Kaufman, N | 1 |
| Champlin, RE | 1 |
| Besedovsky, H | 2 |
| del Rey, A | 2 |
| Normann, SJ | 1 |
| Kirkegaard, C | 1 |
| Hasselbalch, H | 1 |
| Faber, J | 1 |
| Poulsen, S | 1 |
| Bregengård, C | 1 |
| Hasselstrøm, K | 1 |
| Baschieri, L | 1 |
| Antonelli, A | 1 |
| Del Guerra, P | 1 |
| Normann, S | 1 |
| Schardt, M | 1 |
| Saito, T | 1 |
| Bantle, JP | 1 |
| Lee, CK | 1 |
| Levitt, SH | 1 |
| Bellabarba, D | 1 |
| Inada, M | 1 |
| Varsano-Aharon, N | 1 |
| Sterling, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protection From Iatrogenic Hypothyroidism Patients With MBL and Pediatric Patients With HL and Non-HL Needing Radiotherapy on Thyroid Site[NCT05316922] | Phase 3 | 68 participants (Anticipated) | Interventional | 2021-12-13 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and Germinoblastoma
| Article | Year |
|---|---|
Goitrous autoimmune thyroiditis (Hashimoto's disease).
Topics: Adolescent; Adult; Antibodies; Autoimmune Diseases; Child; Child, Preschool; Diagnosis, Differential | 1979 |
1 trial available for thyroxine and Germinoblastoma
| Article | Year |
|---|---|
Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction.
Topics: Adolescent; Adult; Female; Hodgkin Disease; Humans; Hypothyroidism; Lymphoma; Male; Middle Aged; Nec | 1985 |
23 other studies available for thyroxine and Germinoblastoma
| Article | Year |
|---|---|
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres | 2009 |
Primary thyroid lymphoma with elevated free thyroxine level.
Topics: Aged; Autoantibodies; Hashimoto Disease; Humans; Lymphoma; Malaysia; Male; Thyroid Hormones; Thyroid | 2011 |
Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.
Topics: Biomarkers; Blood Glucose; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Stu | 2012 |
Hormonal changes in patients with haematological malignancies.
Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho | 1981 |
Thyroid malignancy in the elderly.
Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Fibrosarcoma; Human | 1982 |
[Preclinical hyperthyroidism in thyroid invasion by tumors of other organs].
Topics: Adenocarcinoma; Carcinoma; Female; Humans; Hyperthyroidism; Kidney Neoplasms; Lymphoma; Male; Middle | 1981 |
The influence of thyroxine, growth hormone and prolactin alone and in combination on the production of prolactin-like activity by splenocytes from Snell dwarf mice.
Topics: Animals; Body Weight; Cells, Cultured; Concanavalin A; Drug Interactions; Female; Growth Hormone; Ly | 1995 |
Diabetes insipidus as first manifestation of primary central nervous system lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Cerebellar Neoplasms; Combined Modality | 1994 |
Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cycl | 1993 |
[Thyroid function in malignant lymphoma].
Topics: Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, N | 1977 |
Thyroid function in malignant lymphoma.
Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; | 1977 |
The non-surgical treatment of thyroid cancer.
Topics: Adenocarcinoma; Age Factors; Aged; Calcitonin; Carcinoma, Papillary; Cell Count; Cell Survival; Chil | 1975 |
Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness.
Topics: Chronic Disease; Humans; Lymphoma; Myocardial Infarction; Thyrotropin; Thyroxine; Triiodothyronine | 1976 |
Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells.
Topics: Animals; Ascitic Fluid; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Chromium Radioisotopes; F | 1975 |
Endocrine and metabolic diseases. Treatment of thyroid diseases--II. Goitre.
Topics: Autoimmune Diseases; Goiter; Goiter, Endemic; Humans; Iodine; Lymphatic Metastasis; Lymphoma; Thyroi | 1976 |
Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis.
Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyr | 1990 |
Thyroid function tests in patients undergoing bone marrow transplantation.
Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Female; Humans; Leukemia; Lymphoma; Male; Thyr | 1990 |
Host endocrine responses during tumor growth.
Topics: Animals; Ascitic Fluid; Corticosterone; Female; Insulin; Lymphoma; Male; Mice; Mice, Inbred BALB C; | 1989 |
Thyroid hormone metabolism in hypermetabolic patients with haematological disorders.
Topics: Adult; Aged; Aged, 80 and over; Female; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Midd | 1989 |
[Therapeutic strategy in thyroid carcinoma].
Topics: Adenoma; Adolescent; Adult; Carcinoma; Carcinoma, Papillary; Child; Female; Follow-Up Studies; Human | 1987 |
Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation.
Topics: Animals; Corticosterone; Female; Inflammation; Insulin; Lymphoma; Male; Mice; Mice, Inbred BALB C; M | 1988 |
Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions.
Topics: Erythrocytes; Humans; Leukemia; Lung Neoplasms; Lymphoma; Superoxide Dismutase; Thyroid Diseases; Th | 1987 |
Thyroxine transport and turnover in major nonthyroidal illness.
Topics: Adenocarcinoma; Adult; Aged; Biological Transport; Blood Proteins; Carcinoma; Carcinoma, Bronchogeni | 1968 |