Page last updated: 2024-11-06

thyroxine and Germinoblastoma

thyroxine has been researched along with Germinoblastoma in 25 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"EL-4 lymphoma cells transplanted to syngeneic C57BL/6J mice induced a biphasic decrease in inflammation and a bi-phasic increase in serum levels of corticosterone."7.67Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation. ( Besedovsky, H; del Rey, A; Normann, S; Schardt, M, 1988)
"The majority of thyroid cancer patients have normal levels of thyroid hormones; they are rarely hyperthyroid, with no obvious clinical features of thyrotoxicosis."5.37Primary thyroid lymphoma with elevated free thyroxine level. ( Din, SW; Ghazali, MZ; Mustafa, S; Yahaya, N, 2011)
"When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l."5.26Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976)
"In an attempt to reduce the incidence of hypothyroidism following irradiation of the neck, we administered oral L-thyroxine in doses sufficient to suppress serum TSH to 20 patients receiving radiation therapy for Hodgkin's disease or other lymphomas."5.05Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction. ( Bantle, JP; Lee, CK; Levitt, SH, 1985)
" The administration of thyroxine (T4) to dwarf mice increased body weight (BW) gain and the number of splenocytes/g BW."3.69The influence of thyroxine, growth hormone and prolactin alone and in combination on the production of prolactin-like activity by splenocytes from Snell dwarf mice. ( Gala, RR, 1995)
"EL-4 lymphoma cells transplanted to syngeneic C57BL/6J mice induced a biphasic decrease in inflammation and a bi-phasic increase in serum levels of corticosterone."3.67Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation. ( Besedovsky, H; del Rey, A; Normann, S; Schardt, M, 1988)
" A cytotoxic effect of this system on a line of mouse ascitic lymphoma cells (LSTRA) is demonstrated here using four different assay systems: 51Cr release, trypan blue exclusion, inhibition of glucose C-1 oxidation, and loss of oncogenicity for mice."3.65Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells. ( Clark, RA; Einstein, AB; Fefer, A; Klebanoff, SJ, 1975)
"Children with cancer were also evaluated after antineoplasic treatment (CAT, n = 17)."1.38Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment. ( Brito, CX; Guerra, RN; Liberio, SA; Lima, MV; Mendonça, C; Mouchrek-Filho, JC; Nascimento, FR; Oliveira-Junior, JJ; Paim, DB; Pereira, AL, 2012)
"The majority of thyroid cancer patients have normal levels of thyroid hormones; they are rarely hyperthyroid, with no obvious clinical features of thyrotoxicosis."1.37Primary thyroid lymphoma with elevated free thyroxine level. ( Din, SW; Ghazali, MZ; Mustafa, S; Yahaya, N, 2011)
"Whenever thyroid lymphoma is suspected, we recommend an ultrasound scan of the thyroid gland and fine needle aspiration biopsy as initial diagnostic procedures."1.29Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases. ( Ikeda, H; Katayama, S; Kuma, K; Matsuzuka, F; Miyauchi, A; Narabayashi, I; Sugawara, M, 1993)
"The mean thyroid dose for irradiated malignant lymphomas in the prospective and the retrospective group was 45 Gy and 43 Gy respectively."1.28Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis. ( Becker, W; Feyerabend, T; Kapp, B; Reiners, C; Richter, E, 1990)
"Patients with malignant lymphoma and acute myeloid leukemia showed a significant decrease in enzyme activity (p less than 0."1.27Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions. ( Saito, T, 1987)
"When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l."1.26Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976)
"The non-surgical treatment of thyroid cancer is outlined."1.25The non-surgical treatment of thyroid cancer. ( Halnan, KE, 1975)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199017 (68.00)18.7374
1990's5 (20.00)18.2507
2000's1 (4.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frick, LR1
Rapanelli, M1
Bussmann, UA1
Klecha, AJ1
Arcos, ML1
Genaro, AM1
Cremaschi, GA1
Yahaya, N1
Din, SW1
Ghazali, MZ1
Mustafa, S1
Guerra, RN1
Oliveira-Junior, JJ1
Mouchrek-Filho, JC1
Liberio, SA1
Lima, MV1
Paim, DB1
Brito, CX1
Mendonça, C1
Nascimento, FR1
Pereira, AL1
Pavelic, K1
Pekic, B1
Gabrilovac, J1
Bratic-Mikes, V1
Boranic, M1
Simpson, WJ1
Gemsenjäger, E1
Girard, J1
Gala, RR1
Balmaceda, CM1
Fetell, MR1
Selman, JE1
Seplowitz, AJ1
Matsuzuka, F1
Miyauchi, A1
Katayama, S1
Narabayashi, I1
Ikeda, H1
Kuma, K1
Sugawara, M1
Worm, AM2
Brinckmeyer, LM2
Nissen, NI2
Doniach, D1
Bottazzo, GF1
Russell, RC1
Halnan, KE1
Carter, JN1
Eastmen, CJ1
Corcoran, JM1
Lazarus, L1
Clark, RA1
Klebanoff, SJ1
Einstein, AB1
Fefer, A1
Evered, DC1
Feyerabend, T1
Kapp, B1
Richter, E1
Becker, W1
Reiners, C1
Hershman, JM1
Eriksen, E1
Kaufman, N1
Champlin, RE1
Besedovsky, H2
del Rey, A2
Normann, SJ1
Kirkegaard, C1
Hasselbalch, H1
Faber, J1
Poulsen, S1
Bregengård, C1
Hasselstrøm, K1
Baschieri, L1
Antonelli, A1
Del Guerra, P1
Normann, S1
Schardt, M1
Saito, T1
Bantle, JP1
Lee, CK1
Levitt, SH1
Bellabarba, D1
Inada, M1
Varsano-Aharon, N1
Sterling, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Protection From Iatrogenic Hypothyroidism Patients With MBL and Pediatric Patients With HL and Non-HL Needing Radiotherapy on Thyroid Site[NCT05316922]Phase 368 participants (Anticipated)Interventional2021-12-13Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thyroxine and Germinoblastoma

ArticleYear
Goitrous autoimmune thyroiditis (Hashimoto's disease).
    Clinics in endocrinology and metabolism, 1979, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Antibodies; Autoimmune Diseases; Child; Child, Preschool; Diagnosis, Differential

1979

Trials

1 trial available for thyroxine and Germinoblastoma

ArticleYear
Thyroxine administration during radiation therapy to the neck does not prevent subsequent thyroid dysfunction.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:11

    Topics: Adolescent; Adult; Female; Hodgkin Disease; Humans; Hypothyroidism; Lymphoma; Male; Middle Aged; Nec

1985

Other Studies

23 other studies available for thyroxine and Germinoblastoma

ArticleYear
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
    Biological psychiatry, 2009, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres

2009
Primary thyroid lymphoma with elevated free thyroxine level.
    Singapore medical journal, 2011, Volume: 52, Issue:9

    Topics: Aged; Autoantibodies; Hashimoto Disease; Humans; Lymphoma; Malaysia; Male; Thyroid Hormones; Thyroid

2011
Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012, Volume: 41, Issue:7

    Topics: Biomarkers; Blood Glucose; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Stu

2012
Hormonal changes in patients with haematological malignancies.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 35, Issue:6

    Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Aged; Chronic Disease; Female; Growth Hormone; Ho

1981
Thyroid malignancy in the elderly.
    Geriatrics, 1982, Volume: 37, Issue:3

    Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Fibrosarcoma; Human

1982
[Preclinical hyperthyroidism in thyroid invasion by tumors of other organs].
    Schweizerische medizinische Wochenschrift, 1981, Oct-17, Volume: 111, Issue:42

    Topics: Adenocarcinoma; Carcinoma; Female; Humans; Hyperthyroidism; Kidney Neoplasms; Lymphoma; Male; Middle

1981
The influence of thyroxine, growth hormone and prolactin alone and in combination on the production of prolactin-like activity by splenocytes from Snell dwarf mice.
    Life sciences, 1995, Volume: 57, Issue:2

    Topics: Animals; Body Weight; Cells, Cultured; Concanavalin A; Drug Interactions; Female; Growth Hormone; Ly

1995
Diabetes insipidus as first manifestation of primary central nervous system lymphoma.
    Neurology, 1994, Volume: 44, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Cerebellar Neoplasms; Combined Modality

1994
Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases.
    Thyroid : official journal of the American Thyroid Association, 1993,Summer, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cycl

1993
[Thyroid function in malignant lymphoma].
    Ugeskrift for laeger, 1977, Sep-05, Volume: 139, Issue:36

    Topics: Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, N

1977
Thyroid function in malignant lymphoma.
    Acta medica Scandinavica, 1977, Volume: 202, Issue:6

    Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse;

1977
The non-surgical treatment of thyroid cancer.
    The British journal of surgery, 1975, Volume: 62, Issue:10

    Topics: Adenocarcinoma; Age Factors; Aged; Calcitonin; Carcinoma, Papillary; Cell Count; Cell Survival; Chil

1975
Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness.
    Clinical endocrinology, 1976, Volume: 5, Issue:6

    Topics: Chronic Disease; Humans; Lymphoma; Myocardial Infarction; Thyrotropin; Thyroxine; Triiodothyronine

1976
Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells.
    Blood, 1975, Volume: 45, Issue:2

    Topics: Animals; Ascitic Fluid; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Chromium Radioisotopes; F

1975
Endocrine and metabolic diseases. Treatment of thyroid diseases--II. Goitre.
    British medical journal, 1976, Feb-07, Volume: 1, Issue:6005

    Topics: Autoimmune Diseases; Goiter; Goiter, Endemic; Humans; Iodine; Lymphatic Metastasis; Lymphoma; Thyroi

1976
Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyr

1990
Thyroid function tests in patients undergoing bone marrow transplantation.
    Bone marrow transplantation, 1990, Volume: 6, Issue:1

    Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Female; Humans; Leukemia; Lymphoma; Male; Thyr

1990
Host endocrine responses during tumor growth.
    Progress in clinical and biological research, 1989, Volume: 288

    Topics: Animals; Ascitic Fluid; Corticosterone; Female; Insulin; Lymphoma; Male; Mice; Mice, Inbred BALB C;

1989
Thyroid hormone metabolism in hypermetabolic patients with haematological disorders.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Midd

1989
[Therapeutic strategy in thyroid carcinoma].
    La Clinica terapeutica, 1987, Jun-30, Volume: 121, Issue:6

    Topics: Adenoma; Adolescent; Adult; Carcinoma; Carcinoma, Papillary; Child; Female; Follow-Up Studies; Human

1987
Hormonal changes following tumor transplantation: factors increasing corticosterone and the relationship of corticosterone to tumor-induced anti-inflammation.
    International journal of cancer, 1988, Jun-15, Volume: 41, Issue:6

    Topics: Animals; Corticosterone; Female; Inflammation; Insulin; Lymphoma; Male; Mice; Mice, Inbred BALB C; M

1988
Superoxide dismutase level in human erythrocytes and its clinical application to the patients with cancers and thyroidal dysfunctions.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1987, Volume: 62, Issue:2

    Topics: Erythrocytes; Humans; Leukemia; Lung Neoplasms; Lymphoma; Superoxide Dismutase; Thyroid Diseases; Th

1987
Thyroxine transport and turnover in major nonthyroidal illness.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Biological Transport; Blood Proteins; Carcinoma; Carcinoma, Bronchogeni

1968